We present a continuous-flow active micromixer based on channel-wall deflection in a polydimethylsiloxane (PDMS) chip for volume flows in the range up to 2 μL s−1 which is intended as a novel unit operation for the microfluidic Braille pin actuated platform. The chip design comprises a main microchannel connected to a series of side channels with dead ends aligned on the Braille pins. Computer-controlled deflection of the side-channel walls induces chaotic advection in the main-channel, which substantially accelerates mixing in low-Reynolds number flow. Sufficient mixing (mixing index MI below 0.1) of volume flows up to 0.5 μL s−1 could be achieved within residence times ~500 ms in the micromixer. As an application, continuous dilution of a yeast cell sample by a ratio down to 1:10 was successfully demonstrated. The mixer is intended to serve as a component of bio-analytical devices or as a unit operation in the microfluidic Braille pin actuated platform.
A time-dependent electrochemical impedance spectroscopy (EIS) model is presented using the finite element method (FEM) to simulate a 2D interdigitated electrode in an aqueous NaCl electrolyte. Developed in COMSOL Multiphysics, the model incorporates ion transport, electric field distribution, Stern layer effects, and electrode sheet resistance, governed by the Poisson and Nernst–Planck equations. This model can predict the transient current response to an applied excitation voltage, which gives information about the dynamics of the electrochemical system. The simulation results are compared with the experimental data, reproducing key features of the measurements. The transient current response indicates the need for multiple excitation cycles to stabilize the impedance measurement. At low frequencies (100 kHz), the voltage drop due to sheet resistance dominates. Moreover, the amplitude of the excitation voltage influences the EIS measurement, higher amplitudes (above 0.1 V) lead to non-linear impedance behavior, particularly at low ion concentrations. Discrepancies at low frequencies suggest that Faradaic processes may need to be incorporated for improved accuracy. Overall, this model provides quantitative insights for optimizing EIS sensor design and highlights critical factors for high-frequency and low-concentration conditions, laying the foundation for future biosensing applications with functionalized electrodes.
Modern infrastructure heavily relies on robust concrete structures, underscoring the critical need for effective monitoring to ensure their safety and durability. This paper addresses this imperative issue by introducing an innovative automated and wireless system for continuous structural monitoring. By employing embedded electrical resistivity sensors coupled with a wireless-based data transmission mechanism, real-time data collection becomes feasible. We provide a general description of the system’s architecture and its application in a pilot study covering the effects of the devices on concrete properties and data transmission. The dielectric properties of concrete specimens were investigated under natural and accelerated curing/degradation and the results were used in the final design of the antenna device. Furthermore, a pilot test comprising four reinforced concrete columns was used to investigate the range of data transmission from inside to outside of the concrete, the effects of the hardware device on the compressive strength and concrete distribution in the columns, and the data transmission quality in real time under realistic exposure conditions.