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Prof. Dr. Sumin BIAN
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Academic Career Length
11Years (2016-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications2 October 2023 in ACS Nano
Journal Article
SYSisi Yan
Sisi Yan
JSJiacheng Sun
Jiacheng Sun
BCBin Chen
Bin ChenLWLang Wang
Lang Wang
SBSumin BIAN
Sumin BIANGMGuowen Meng
Guowen Meng +3
23 January 2023 in Analytica Chimica Acta
Journal Article
YZYuqiao Zheng
Yuqiao Zheng
XSXixi Song
Xixi Song
ZFZina Fredj
Zina Fredj
SBSumin BIAN
Sumin BIAN
Mohamad Sawan31 August 2023 in Journal of Pharmaceutical Analysis
Journal Article
XSXixi Song
Xixi Song
ZFZina Fredj
Zina Fredj
YZYuqiao Zheng
Yuqiao Zheng
HZHongyong Zhang
Hongyong Zhang
GRGuoguang Rong
Guoguang Rong
Mohamad Sawan +1
Waterborne viruses that can be harmful to human health pose significant challenges globally, affecting health care systems and the economy. Identifying these waterborne pathogens is essential for preventing diseases and protecting public health. However, handling complex samples such as human and wastewater can be challenging due to their dynamic and complex composition and the ultralow concentration of target analytes. This review presents a comprehensive overview of the latest breakthroughs in waterborne virus biosensors. It begins by highlighting several promising strategies that enhance the sensing performance of optical and electrochemical biosensors in human samples. These strategies include optimizing bioreceptor selection, transduction elements, signal amplification, and integrated sensing systems. Furthermore, the insights gained from biosensing waterborne viruses in human samples are applied to improve biosensing in wastewater, with a particular focus on sampling and sample pretreatment due to the dispersion characteristics of waterborne viruses in wastewater. This review suggests that implementing a comprehensive system that integrates the entire waterborne virus detection process with high-accuracy analysis could enhance virus monitoring. These findings provide valuable insights for improving the effectiveness of waterborne virus detection, which could have significant implications for public health and environmental management.
23 August 2017 in Drug Testing and Analysis
Journal Article
SBSumin BIAN
Sumin BIANJLJiadi Lu
Jiadi Lu
FDFilip Delport
Filip Delport
SVSeverine Vermeire
Severine VermeireDSDragana Spasic
Dragana Spasic
AGAnn Gils
Ann Gils
+1
30 April 2025 in Journal of Pharmaceutical Analysis
Journal Article
Brain organoid-on-chip platforms have emerged as groundbreaking tools in neural disease modeling and drug discovery, offering a unique and highly accurate simulation of human organ physiology and function compared with traditional cell culture systems. This technology is a harmonious fusion of organ-on-a-chip and organoid culture technologies, leveraging their strengths to provide the most realistic in vitro replication of the in vivo environment, both physically and biologically. As both technologies continue to advance rapidly, this platform is highly promising in vitro platform for disease modeling. In this review, we summarize the historical developments, recent advancements, limitations, and future prospects of brain organoid-on-chip technology, aiming to illuminate the transformative potential of this platform in advancing our understanding and treatment of neural diseases.
Journal Article
YZYuqiao Zheng
Yuqiao ZhengSBSumin BIAN
Sumin BIANJSJiacheng Sun
Jiacheng SunLWLiaoyong Wen
Liaoyong Wen
Guoguang RongMohamad SawanCost-effective, rapid, and sensitive detection of SARS-CoV-2, in high-throughput, is crucial in controlling the COVID-19 epidemic. In this study, we proposed a vertical microcavity and localized surface plasmon resonance hybrid biosensor for SARS-CoV-2 detection in artificial saliva and assessed its efficacy. The proposed biosensor monitors the valley shifts in the reflectance spectrum, as induced by changes in the refractive index within the proximity of the sensor surface. A low-cost and fast method was developed to form nanoporous gold (NPG) with different surface morphologies on the vertical microcavity wafer, followed by immobilization with the SARS-CoV-2 antibody for capturing the virus. Modeling and simulation were conducted to optimize the microcavity structure and the NPG parameters. Simulation results revealed that NPG-deposited sensors performed better in resonance quality and in sensitivity compared to gold-deposited and pure microcavity sensors. The experiment confirmed the effect of NPG surface morphology on the biosensor sensitivity as demonstrated by simulation. Pre-clinical validation revealed that 40% porosity led to the highest sensitivity for SARS-CoV-2 pseudovirus at 319 copies/mL in artificial saliva. The proposed automatic biosensing system delivered the results of 100 samples within 30 min, demonstrating its potential for on-site coronavirus detection with sufficient sensitivity.
About Me
Sumin Bian is a research associate professor at Westlake University. She obtained her Ph.D. in Pharmaceutical Sciences from KU Leuven, Belgium in 2018. Currently, Sumin has multidisciplinary research interests in pharmaceutical science, biosensors, and organoids-on-chips for personalized treatment applications. To date, she has authored 30 articles with 17 as the (co-)first/corresponding author in peer-reviewed journals (including Biosensors & Bioelectronics, J. Pharm. Anal. (Cover Paper; Best Paper Award), Anal. Chim. Acta and Front. Bioeng. Biotechnol. and as a strong collaborator contributed to works published in ACS Nano, Clin Gastroenterol Hepatol, J Crohns Colitis and Aliment Pharmacol Ther. She holds three national innovation and three PCTs as the first applicant. She was awarded multiple Chinese National Scholarships in recognition of her passionate pursuit of science during her educational endeavors and doctoral research scholarships from both the China Scholarship Council and KU Leuven. She was granted the Travel Award by United European Gastroenterology Week (Aug-2016), the Best Poster Award in Westlake International Symposium in Engineering (Oct-2021), the National Silver Award in the first China Postdoctoral Innovation & Entrepreneurship Competition (21-Dec-2021) and Best Staff Award (30-Aug-2022). She serves as a Youth Editor of The Innovation-Cell Press. In 2022, she was awarded a Youth Science Fund grant from the National Natural Science Foundation of China.