Bakhtawar Shafique

Ms. Bakhtawar Shafique

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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12 August 2021 in Molecules
Verified
Journal Article
Open access
PDF file
Modassar RanjhaModassar Ranjha
Modassar Ranjha
RKRabia Kanwal
Rabia Kanwal
BSBakhtawar Shafique
Bakhtawar Shafique
RARai Naveed Arshad
Rai Naveed Arshad
Shafeeqa IrfanShafeeqa Irfan
Shafeeqa Irfan
Rana Muhammad AadilRana Muhammad Aadil
Rana Muhammad Aadil
Different parts of a plant (seeds, fruits, flower, leaves, stem, and roots) contain numerous biologically active compounds called “phytoconstituents” that consist of phenolics, minerals, amino acids, and vitamins. The conventional techniques applied to extract these phytoconstituents have several drawbacks including poor performance, low yields, more solvent use, long processing time, and thermally degrading by-products. In contrast, modern and advanced extraction nonthermal technologies such as pulsed electric field (PEF) assist in easier and efficient identification, characterization, and analysis of bioactive ingredients. Other advantages of PEF include cost-efficacy, less time, and solvent consumption with improved yields. This review covers the applications of PEF to obtain bioactive components, essential oils, proteins, pectin, and other important materials from various parts of the plant. Numerous studies compiled in the current evaluation concluded PEF as the best solution to extract phytoconstituents used in the food and pharmaceutical industries. PEF-assisted extraction leads to a higher yield, utilizes less solvents and energy, and it saves a lot of time compared to traditional extraction methods. PEF extraction design should be safe and efficient enough to prevent the degradation of phytoconstituents and oils.

14 August 2021 in Processes
Verified
Journal Article
Open access
PDF file
Modassar RanjhaModassar Ranjha
Modassar Ranjha
Shafeeqa IrfanShafeeqa Irfan
Shafeeqa Irfan
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
BSBakhtawar Shafique
Bakhtawar Shafique
RKRabia Kanwal
Rabia Kanwal
Rana Muhammad AadilRana Muhammad Aadil
Rana Muhammad Aadil
Traditional extraction techniques have lost their optimum performance because of rising consumer demand and novel technologies. In this regard, several techniques were developed by humans for the extraction of plant materials from various indigenous sources, which are no longer in use. Many of the techniques are not efficient enough to extract maximum plant material. By this time, evolution in extraction has led to development of various techniques including microfiltration, pulsed electric fields, high pressure, microwave assistance, enzyme assistance, supercritical fluid, subcritical fluid and ultrasonication. These innovations in food processing/extraction are known as “Green Food Processing”. These technologies were basically developed by focusing on three universal parameters: simplicity, energy efficiency and economy. These green technologies are practical in a number of different food sectors, mostly for preservation, inhibition of microorganisms, inactivation of enzymes and extraction of plant material. Like the others, ultrasonication could also be used for the said purposes. The primary objective of this review is to confine the potential use of ultrasonication for extraction of oils, pectin and phytochemicals by reviewing the literature systematically.

25 November 2021 in Applied Sciences
Verified
Journal Article
Open access
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Modassar RanjhaModassar Ranjha
Modassar Ranjha
BSBakhtawar Shafique
Bakhtawar Shafique
MBMaria Batool
Maria Batool
Przemysław Łukasz KowalczewskiPrzemysław Łukasz Kowalczewski
Przemysław Łukasz Kowalczewski
QSQayyum Shehzad
Qayyum Shehzad
Rana Muhammad AadilRana Muhammad Aadil
Rana Muhammad Aadil
Several products consist of probiotics that are available in markets, and their potential uses are growing day by day, mainly because some strains of probiotics promote the health of gut microbiota, especially Furmicutes and Bacteroidetes, and may prevent certain gastrointestinal tract (GIT) problems. Some common diseases are inversely linked with the consumption of probiotics, i.e., obesity, type 2 diabetes, autism, osteoporosis, and some immunological disorders, for which the disease progression gets delayed. In addition to disease mitigating properties, these microbes also improve oral, nutritional, and intestinal health, followed by a robust defensive mechanism against particular gut pathogens, specifically by antimicrobial substances and peptides producing probiotics (AMPs). All these positive attributes of probiotics depend upon the type of microbial strains dispensed. Lactic acid bacteria (LAB) and Bifidobacteria are the most common microbes used, but many other microbes are available, and their use depends upon origin and health-promoting properties. This review article focuses on the most common probiotics, their health benefits, and the alleviating mechanisms against chronic kidney diseases (CKD), type 1 diabetes (T1D), type 2 diabetes (T2D), gestational diabetes mellitus (GDM), and obesity.

12 March 2023 in Trends in Food Science & Technology
Verified
Journal Article
Closed access
Modassar RanjhaModassar Ranjha
Modassar Ranjha
BSBakhtawar Shafique
Bakhtawar Shafique
Rana Muhammad AadilRana Muhammad Aadil
Rana Muhammad Aadil
Muhammad Faisal ManzoorMuhammad Faisal Manzoor
Muhammad Faisal Manzoor
Junhu ChengJunhu Cheng
Junhu Cheng

28 December 2022 in Microorganisms
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Journal Article
Open access
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BSBakhtawar Shafique
Bakhtawar Shafique
Modassar RanjhaModassar Ranjha
Modassar Ranjha
MMMian Anjum Murtaza
Mian Anjum Murtaza
Noman WalayatNoman Walayat
Noman Walayat
Asad NawazAsad Nawaz
Asad Nawaz
Salam IbrahimSalam Ibrahim
Salam Ibrahim
Bacteriocins are ribosomal-synthesized peptides or proteins produced by bacterial strains and can inhibit pathogenic bacteria. Numerous factors influence the potential activity of bacteriocins in food matrices. For example, food additives usage, chemical composition, physical conditions of food, and sensitivity of proteolytic enzymes can constrain the application of bacteriocins as beneficial food preservatives. However, novel bacteriocin nanoencapsulation has appeared as an encouraging solution. In this review, we highlight the bacteriocins produced by Gram-negative bacteria and Gram-positive bacteria including lactic acid bacteria that have shown positive results as potential food preservatives. In addition, this review encompasses the major focus on bacteriocins encapsulation with nanotechnology to enhance the antimicrobial action of bacteriocins. Several strategies can be employed to encapsulate bacteriocins; however, the nanotechnological approach is one of the most effective strategies for avoiding limitations. Nanoparticles such as liposomes, chitosan, protein, and polysaccharides have been discussed to show their importance in the nanoencapsulation method. The nanoparticles are combined with bacteriocins to develop the nano-encapsulated bacteriocins from Gram-negative and Gram-positive bacteria including LAB. In food systems, nanoencapsulation enhances the stability and antimicrobial functionality of active peptides. This nanotechnological application provides a formulation of a broad range of antimicrobial peptides at the industry-scale level. Nano-formulated bacteriocins have been discussed along with examples to show a broader antimicrobial spectrum, increase bacteriocins’ applicability, extend antimicrobial spectrum and enhance stability.

8 September 2022 in Open Life Sciences
Verified
Journal Article
Open access
PDF file
WKWaseem Khalid
Waseem Khalid
MNMehr Nisa
Mehr Nisa
Modassar RanjhaModassar Ranjha
Modassar Ranjha
Maria Barbara RóżańskaMaria Barbara Różańska
Maria Barbara Różańska
Shafeeqa IrfanShafeeqa Irfan
Shafeeqa Irfan
Przemysław Łukasz KowalczewskiPrzemysław Łukasz Kowalczewski
Przemysław Łukasz Kowalczewski
Plant-based foods are becoming an increasingly frequent topic of discussion, both scientific and social, due to the dissemination of information and exchange of experiences in the media. Plant-based diets are considered beneficial for human health due to the supply of many valuable nutrients, including health-promoting compounds. Replacing meat-based foods with plant-based products will provide many valuable compounds, including antioxidants, phenolic compounds, fibers, vitamins, minerals, and some ω3 fatty acids. Due to their high nutritional and functional composition, plant-based foods are beneficial in acute and chronic diseases. This article attempts to review the literature to present the most important data on nutrients of plant-based foods that can then help in the prevention of many diseases, such as different infections, such as coronavirus disease, pneumonia, common cold and flu, asthma, and bacterial diseases, such as bronchitis. A properly structured plant-based diet not only provides the necessary nutrients but also can help in the prevention of many diseases.