Diabetes is a widespread disease in the world and can lead to diabetic retinopathy, macular edema, and other obvious microvascular complications in the retina of the human eye. This study attempts to detect diabetic retinopathy (DR), which has been the main reason behind the blindness of people in the last decade. Timely or early treatment is necessary to prevent some DR complications and control blood glucose. DR is very difficult to detect in time-consuming manual diagnosis because of its diversity and complexity. This work utilizes a deep learning application, a convolutional neural network (CNN), in fundus photography to distinguish the stages of DR. The images dataset in this study is obtained from Xiangya No. 2 Hospital Ophthalmology (XHO), Changsha, China, which is very large, little and the labels are unbalanced. Thus, this study first solves the problem of the existing dataset by proposing a method that uses preprocessing, regularization, and augmentation steps to increase and prepare the image dataset of XHO for training and improve performance. Then, it takes the advantages of the power of CNN with different residual neural network (ResNet) structures, namely, ResNet-101, ResNet-50, and VggNet-16, to detect DR on XHO datasets. ResNet-101 achieved the maximum level of accuracy, 0.9888, with a training loss of 0.3499 and a testing loss of 0.9882. ResNet-101 is then assessed on 1787 photos from the HRF, STARE, DIARETDB0, and XHO databases, achieving an average accuracy of 0.97, which is greater than prior efforts. Results prove that the CNN model (ResNet-101) has better accuracy than ResNet-50 and VggNet-16 in DR image classification.

Recently, convolutional neural networks have shown good performance in many counterfeit detection tasks. However, accurate counterfeit detection is still challenging due to the following three issues: (1) fine-grained classification, (2) class imbalance, and (3) high imitation samples. To address these issues, we propose a hybrid attention network (HANet) for counterfeit luxury handbag detection. In HANet, a hybrid attention module is first designed. Compared with existing methods that directly use classic CNNs for counterfeit detection, the HA module jointly uses a channel attention unit and a spatial attention unit to learn important information on both the channel and spatial dimensions. The HA modules can be easily integrated into the ResNet architecture to enhance the discriminative representation ability of CNNs, so as to help the network find subtle differences between the real and counterfeit products. In addition, an appraiser-guided loss is proposed to train HANet. Considering the factor of class imbalance and high imitation samples, the proposed loss gives the counterfeit class a higher weighting, and meanwhile gives the high imitation samples a much higher weighting. The proposed loss introduces the knowledge of appraisers, which allows HANet to not only treat real and counterfeit samples relatively fairly, but also pay more attention to the learning of difficult samples. To evaluate the performance of our method, we have constructed a well-benchmarked luxury handbag dataset. On this dataset, the performance of HANet, ResNet50, and the state-of-the-art attention methods is compared. The results demonstrate that HANet achieve superior performance against all its competitors.