Introduction: the article discusses the effect of the complex of active mineral additives consisting of silica and fly ash, and a fine aggregate, including finely ground natural-white quartz sand for partial replacement of river sand, on the mechanical properties of high-strength concrete containing steel fiber. Materials and methods: high-strength concrete containing Dramix^®3D 65/35 steel fiber in the amount of 100 kg per 1 m³ of concrete mixture was suggested where 22% to 100% of river sand was replaced by finely ground white natural sand of the particle size of 5 to 1800 μm and containing the complex of active mineral additives for partial replacement of cement as part of a multicomponent binder, consisting of low-calcium fly ash of thermal power plants and silica and containing, respectively, 20, 30, 40% fly ash and from 5 to 15% silica by weight of the binder. Results: research results have shown that 100% replacement of river sand with finely ground natural white sand, in concrete containing 20% of the mass as part of a multicomponent binder, fly ash and from 5 to 15% by weight of silica, contributes to the increase of its strength properties: the values of concrete compressive strength after 28 days were in the range from 118.5 to 128 MPa, tensile strength during bending and splitting, respectively, from 18.8 to 25.4 MPa and from 10.2 to 11.9 MPa, which is higher than the strength of concrete samples containing river sand. Conclusions: the achieved results have demonstrated the efficiency of using finely ground natural white sand as an alternative to river sand for producing high-strength concrete, thus helping to save the river sand resources in Vietnam. The use of fly ash and micro silicon, which are power and metallurgy wastes, as part of a multicomponent binder in order to partially replace cement reduces the carbon footprint in the production of binders and will also have a beneficial effect on environmental protection against industrial waste pollution.