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Marcello Campagna
Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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Journal article
Published: 28 April 2021 in Environmental Health
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Background The International Agency for Research on Cancer (IARC) recently classified glyphosate, the most used herbicide worldwide, as a probable human carcinogen. We inquired into the association between occupational exposure to glyphosate and risk of lymphoma subtypes in a multicenter case-control study conducted in Italy. Methods The Italian Gene-Environment Interactions in Lymphoma Etiology (ItGxE) study took place in 2011–17 in six Italian centres. Overall, 867 incident lymphoma cases and 774 controls participated in the study. Based on detailed questionnaire information, occupational experts classified duration, confidence, frequency, and intensity of exposure to glyphosate for each study subject. Using unconditional regression analysis, we modelled risk of major lymphoma subtypes associated with exposure to glyphosate adjusted by age, gender, education, and study centre. Results Very few study subjects (2.2%) were classified as ever exposed to glyphosate. Risk of follicular lymphoma (FL) was elevated 7-fold in subjects classified as ever exposed to glyphosate with medium-high confidence, 4.5-fold in association with medium-high cumulative exposure level, 12-fold with medium-high exposure intensity, and 6-fold with exposure for 10 days or more per year. Significant upward trends were detected with all the exposure metrics, but duration. The overall p-value for an upward trend with four independent metrics was 1.88 × 10− 4. There was no association with risk of lymphoma (any subtype), Non Hodgkin Lymphoma, B-cell lymphoma, or the major lymphoma subtypes other than FL. Conclusions Our findings provide limited support to the IARC decision to classify glyphosate as Group 2A human carcinogen.

ACS Style

Federico Meloni; Giannina Satta; Marina Padoan; Andrea Montagna; Ilaria Pilia; Alessandra Argiolas; Sara Piro; Corrado Magnani; Angela Gambelunghe; Giacomo Muzi; Giovanni Maria Ferri; Luigi Vimercati; Roberta Zanotti; Aldo Scarpa; Mariagrazia Zucca; Sara De Matteis; Marcello Campagna; Lucia Miligi; Pierluigi Cocco. Occupational exposure to glyphosate and risk of lymphoma:results of an Italian multicenter case-control study. Environmental Health 2021, 20, 1 -8.

AMA Style

Federico Meloni, Giannina Satta, Marina Padoan, Andrea Montagna, Ilaria Pilia, Alessandra Argiolas, Sara Piro, Corrado Magnani, Angela Gambelunghe, Giacomo Muzi, Giovanni Maria Ferri, Luigi Vimercati, Roberta Zanotti, Aldo Scarpa, Mariagrazia Zucca, Sara De Matteis, Marcello Campagna, Lucia Miligi, Pierluigi Cocco. Occupational exposure to glyphosate and risk of lymphoma:results of an Italian multicenter case-control study. Environmental Health. 2021; 20 (1):1-8.

Chicago/Turabian Style

Federico Meloni; Giannina Satta; Marina Padoan; Andrea Montagna; Ilaria Pilia; Alessandra Argiolas; Sara Piro; Corrado Magnani; Angela Gambelunghe; Giacomo Muzi; Giovanni Maria Ferri; Luigi Vimercati; Roberta Zanotti; Aldo Scarpa; Mariagrazia Zucca; Sara De Matteis; Marcello Campagna; Lucia Miligi; Pierluigi Cocco. 2021. "Occupational exposure to glyphosate and risk of lymphoma:results of an Italian multicenter case-control study." Environmental Health 20, no. 1: 1-8.

Journal article
Published: 27 April 2021 in International Journal of Environmental Research and Public Health
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Background: The main anthropic sources of exposure to airborne benzene include vehicular traffic, cigarette smoke, and industrial emissions. Methods: To detect early genotoxic effects of environmental exposure to benzene, we monitored environmental, personal, and indoor airborne benzene in children living in an urban area and an area near a petrochemical plant. We also used urinary benzene and S-phenylmercapturic acid (S-PMA) as biomarkers of benzene exposure and urinary 8-hydroxydeoxyguanosine (8-OHdG) as a biomarker of early genotoxic effects. Results: Although always below the European Union limit of 5 μg/m3, airborne benzene levels were more elevated in the indoor, outdoor, and personal samples from the industrial surroundings compared to the urban area (p = 0.026, p = 0.005, and p = 0.001, respectively). Children living in the surroundings of the petrochemical plant had urinary benzene values significantly higher than those from the urban area in both the morning and evening samples (p = 0.01 and p = 0.02, respectively). Results of multiple regression modelling showed that age was a significant predictor of 8-OHdG excretion, independent of the sampling hour. Moreover, at the low exposure level experienced by the children participating in this study, neither personal or indoor airborne benzene level, nor personal monitoring data, affected 8-OHdG excretion. Conclusions: Our results suggest the importance of biological monitoring of low-level environmental exposure and its relation to risk of genotoxic effects among children.

ACS Style

Ilaria Pilia; Marcello Campagna; Gabriele Marcias; Daniele Fabbri; Federico Meloni; Giovanna Spatari; Danilo Cottica; Claudio Cocheo; Elena Grignani; Fabio De-Giorgio; Pierluigi Cocco; Ernesto D’Aloja. Biomarkers of Low-Level Environmental Exposure to Benzene and Oxidative DNA Damage in Primary School Children in Sardinia, Italy. International Journal of Environmental Research and Public Health 2021, 18, 4644 .

AMA Style

Ilaria Pilia, Marcello Campagna, Gabriele Marcias, Daniele Fabbri, Federico Meloni, Giovanna Spatari, Danilo Cottica, Claudio Cocheo, Elena Grignani, Fabio De-Giorgio, Pierluigi Cocco, Ernesto D’Aloja. Biomarkers of Low-Level Environmental Exposure to Benzene and Oxidative DNA Damage in Primary School Children in Sardinia, Italy. International Journal of Environmental Research and Public Health. 2021; 18 (9):4644.

Chicago/Turabian Style

Ilaria Pilia; Marcello Campagna; Gabriele Marcias; Daniele Fabbri; Federico Meloni; Giovanna Spatari; Danilo Cottica; Claudio Cocheo; Elena Grignani; Fabio De-Giorgio; Pierluigi Cocco; Ernesto D’Aloja. 2021. "Biomarkers of Low-Level Environmental Exposure to Benzene and Oxidative DNA Damage in Primary School Children in Sardinia, Italy." International Journal of Environmental Research and Public Health 18, no. 9: 4644.

Journal article
Published: 20 March 2021 in BMC Musculoskeletal Disorders
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Background General physiotherapy is a common means of rehabilitation after surgery for proximal humeral fracture (PHF). Better-targeted exercises seem worthy of investigation and the aim of this study was to assess the efficacy of a rehabilitation program including task-oriented exercises in improving disability, pain, and quality of life in patients after a PHF. Methods By means of a randomized controlled trial with one-year follow-up, 70 working patients (mean age of 49 ± 11 years; 41 females), who were selected for open reduction and internal fixation with plates caused by PHF, were randomized to be included in an experimental (n = 35) or control group (n = 35). There was a permuted-block randomization plan, and a list of program codes was previously created; subsequently, an automatic assignment system was used to conceal the allocation. The first group underwent a supervised rehabilitation program of task-oriented exercises based on patients’ specific job activities, and occupational therapy. The second group underwent general physiotherapy, including supervised mobility, strengthening and stretching exercises. Both groups individually followed programs of 60-min session three times per week for 12 weeks in the outpatient setting. The Disability Arm Shoulder Hand questionnaire (DASH; scores range from 0 to 100; primary outcome), a Pain intensity Numerical Rating Scale (scores range 0 to 10; secondary outcomes), and the Short-Form Health Survey (scores range from 0 to 100; secondary outcomes) assessed the interventions. Participants were evaluated before surgery, before and after rehabilitation (primary endpoint), and at the one-year follow-up (secondary endpoint). A linear mixed model analysis for repeated measures was carried out for each outcome measure (p < 0.05). Results Time, group and time by group showed significant effects for all outcome measures in favour of the experimental group. The DASH and the DASH work achieved clinically important between-group differences of 16.0 points (95% confidence interval [C.I.] 7.3 to 24.7) and 19.7 (95% C.I. 9.0 to 30.5) at follow-up, respectively. The NRS achieved a between-group difference of 2.9 (95% C.I. 1.0 to 3.9) at follow-up. As for SF-36, there were between-group differences ranging from 17.9 to 37.0 at follow-up. Conclusions A rehabilitation program based on task-oriented exercises was useful in improving disability, pain, and quality of life in working patients after PHFs. Improvements lasted for at least 12 months. Trial registration On 16/12/2019, the trial was retrospectively registered in the ISRCTN registry with the ID number 17996552.

ACS Style

Marco Monticone; Igor Portoghese; Daniele Cazzaniga; Valentina Liquori; Giuseppe Marongiu; Antonio Capone; Marcello Campagna; Giovanni Zatti. Task-oriented exercises improve disability of working patients with surgically-treated proximal humeral fractures. A randomized controlled trial with one-year follow-up. BMC Musculoskeletal Disorders 2021, 22, 1 -11.

AMA Style

Marco Monticone, Igor Portoghese, Daniele Cazzaniga, Valentina Liquori, Giuseppe Marongiu, Antonio Capone, Marcello Campagna, Giovanni Zatti. Task-oriented exercises improve disability of working patients with surgically-treated proximal humeral fractures. A randomized controlled trial with one-year follow-up. BMC Musculoskeletal Disorders. 2021; 22 (1):1-11.

Chicago/Turabian Style

Marco Monticone; Igor Portoghese; Daniele Cazzaniga; Valentina Liquori; Giuseppe Marongiu; Antonio Capone; Marcello Campagna; Giovanni Zatti. 2021. "Task-oriented exercises improve disability of working patients with surgically-treated proximal humeral fractures. A randomized controlled trial with one-year follow-up." BMC Musculoskeletal Disorders 22, no. 1: 1-11.

Journal article
Published: 03 March 2021 in International Journal of Environmental Research and Public Health
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Airport activity causes the emission of particulate matter and noise, two environmental contaminants and potential health hazards, particularly for the personnel operating nearby taxiways. We explored the association between exposure to fine/ultrafine particles (UFPs) and noise with heart rate variability (HRV), an early indicator of cardiovascular autonomic response, among a sample of airport ground staff. Between May and June 2018, thirty-four male operators (mean age = 43 years and SD = 6.7) underwent personal monitoring of exposure to nanoparticles and noise, and HRV during their work activity. We conducted univariate and multivariate analysis to test the effect of UFP and noise exposure HRV. Total Lung Deposition Surface Area (LDSA) was significantly associated with a decrease in HRV Total Power and Triangular index (β = −0.038 p = 0.016 and β = −7.8 × 10−5, p = 0.042, respectively). Noise peak level showed an opposite effect, which was significant for Total Power (β = 153.03, p = 0.027), and for Triangular index (β = 0.362, p = 0.035). Further investigation is warranted to clarify the effect of the concurrent exposure to UFPs and noise on early changes of cardiac autonomic regulation.

ACS Style

Luigi Lecca; Gabriele Marcias; Michele Uras; Federico Meloni; Nicola Mucci; Francesca Larese Filon; Giorgio Massacci; Giorgio Buonanno; Pierluigi Cocco; Marcello Campagna. Response of the Cardiac Autonomic Control to Exposure to Nanoparticles and Noise: A Cross-Sectional Study of Airport Ground Staff. International Journal of Environmental Research and Public Health 2021, 18, 2507 .

AMA Style

Luigi Lecca, Gabriele Marcias, Michele Uras, Federico Meloni, Nicola Mucci, Francesca Larese Filon, Giorgio Massacci, Giorgio Buonanno, Pierluigi Cocco, Marcello Campagna. Response of the Cardiac Autonomic Control to Exposure to Nanoparticles and Noise: A Cross-Sectional Study of Airport Ground Staff. International Journal of Environmental Research and Public Health. 2021; 18 (5):2507.

Chicago/Turabian Style

Luigi Lecca; Gabriele Marcias; Michele Uras; Federico Meloni; Nicola Mucci; Francesca Larese Filon; Giorgio Massacci; Giorgio Buonanno; Pierluigi Cocco; Marcello Campagna. 2021. "Response of the Cardiac Autonomic Control to Exposure to Nanoparticles and Noise: A Cross-Sectional Study of Airport Ground Staff." International Journal of Environmental Research and Public Health 18, no. 5: 2507.

Journal article
Published: 16 December 2020 in International Journal of Environmental Research and Public Health
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In the Job Demand–Control–Support (JDCS) model, the combination of job demands, job control, and social support was hypothesized to lead to eight different constellations of job types. According to the model, these constellations are linked to wellbeing/health and learning outcomes. In the last three decades, these constellations of job types have been investigated by adopting a variable-centered perspective. However, latent profile analyses (LPA) enable a person-centered approach and empirically capture constellations of job types. In the present study, we used LPA to empirically identify distinct profiles of JDCS among Italian healthcare workers. Furthermore, we investigated the role of social stressors (workplace relationships and coworkers’ incivility) as antecedents of these profiles and the association of these profiles with job burnout and work motivation. Results from LPA (n = 1671) revealed four profiles: Isolated Prisoner, Participatory Leader, Moderate Strain, and Low Strain. Negative relationships at work and coworkers’ incivility increased the chances of being included in both Isolated prisoner and Participatory Leader profiles. Finally, the Isolated Prisoner and Moderate Strain profiles showed the highest levels of emotional exhaustion and cynicism and the lower levels of intrinsic work motivation. This study extends previous JDCS research, highlighting that researchers should consider empirically identified profiles rather than theoretically defined subgroups. Implications for stress theory, future research, and practice are discussed.

ACS Style

Igor Portoghese; Maura Galletta; Michael P. Leiter; Gabriele Finco; Ernesto D’Aloja; Marcello Campagna. Job Demand–Control–Support Latent Profiles and Their Relationships with Interpersonal Stressors, Job Burnout, and Intrinsic Work Motivation. International Journal of Environmental Research and Public Health 2020, 17, 9430 .

AMA Style

Igor Portoghese, Maura Galletta, Michael P. Leiter, Gabriele Finco, Ernesto D’Aloja, Marcello Campagna. Job Demand–Control–Support Latent Profiles and Their Relationships with Interpersonal Stressors, Job Burnout, and Intrinsic Work Motivation. International Journal of Environmental Research and Public Health. 2020; 17 (24):9430.

Chicago/Turabian Style

Igor Portoghese; Maura Galletta; Michael P. Leiter; Gabriele Finco; Ernesto D’Aloja; Marcello Campagna. 2020. "Job Demand–Control–Support Latent Profiles and Their Relationships with Interpersonal Stressors, Job Burnout, and Intrinsic Work Motivation." International Journal of Environmental Research and Public Health 17, no. 24: 9430.

Multicenter study
Published: 04 December 2020 in Frontiers in Immunology
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AimSARS-CoV-2 infection is a world-wide public health problem. Several aspects of its pathogenesis and the related clinical consequences still need elucidation. In Italy, Sardinia has had very low numbers of infections. Taking advantage of the low genetic polymorphism in the Sardinian population, we analyzed clinical, genetic and immunogenetic factors, with particular attention to HLA class I and II molecules, to evaluate their influence on susceptibility to SARS-CoV-2 infection and the clinical outcome.Method and MaterialsWe recruited 619 healthy Sardinian controls and 182 SARS-CoV-2 patients. Thirty-nine patients required hospital care and 143 were without symptoms, pauci-symptomatic or with mild disease. For all participants, we collected demographic and clinical data and analyzed the HLA allele and haplotype frequencies.ResultsMale sex and older age were more frequent in hospitalized patients, none of whom had been vaccinated during the previous seasonal flu vaccination campaignes. Compared to the group of asymptomatic or pauci-symptomatic patients, hospitalized patients also had a higher frequency of autoimmune diseases and glucose-6-phosphate-dehydrogenase (G6PDH) deficiency. None of these patients carried the beta-thalassemia trait, a relatively common finding in the Sardinian population. The extended haplotype HLA-A*02:05, B*58:01, C*07:01, DRB1*03:01 [OR 0.1 (95% CI 0–0.6), Pc = 0.015] was absent in all 182 patients, while the HLA-C*04:01 allele and the three-loci haplotype HLA-A*30:02, B*14:02, C*08:02 [OR 3.8 (95% CI 1.8–8.1), Pc = 0.025] were more frequently represented in patients than controls. In a comparison between in-patients and home care patients, the HLA-DRB1*08:01 allele was exclusively present in the hospitalized patients [OR > 2.5 (95% CI 2.7–220.6), Pc = 0.024].ConclusionThe data emerging from our study suggest that the extended haplotype HLA-A*02:05, B*58:01, C*07:01, DRB1*03:01 has a protective effect against SARS-CoV-2 infection in the Sardinian population. Genetic factors that resulted to have a negative influence on the disease course were presence of the HLA-DRB1*08:01 allele and G6PDH deficiency, but not the beta-thalassemic trait. Absence of influenza vaccination could be a predisposing factor for more severe disease.

ACS Style

Roberto Littera; Marcello Campagna; Silvia Deidda; Goffredo Angioni; Selene Cipri; Maurizio Melis; Davide Firinu; Simonetta Santus; Alberto Lai; Rita Porcella; Sara Lai; Stefania Rassu; Rosetta Scioscia; Federico Meloni; Daniele Schirru; William Cordeddu; Marta Anna Kowalik; Maria Serra; Paola Ragatzu; Mauro Giovanni Carta; Stefano Del Giacco; Angelo Restivo; Simona Deidda; Sandro Orrù; Antonella Palimodde; Roberto Perra; Germano Orrù; Maria Conti; Cinzia Balestrieri; Giancarlo Serra; Simona Onali; Francesco Marongiu; Andrea Perra; Luchino Chessa. Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience. Frontiers in Immunology 2020, 11, 605688 .

AMA Style

Roberto Littera, Marcello Campagna, Silvia Deidda, Goffredo Angioni, Selene Cipri, Maurizio Melis, Davide Firinu, Simonetta Santus, Alberto Lai, Rita Porcella, Sara Lai, Stefania Rassu, Rosetta Scioscia, Federico Meloni, Daniele Schirru, William Cordeddu, Marta Anna Kowalik, Maria Serra, Paola Ragatzu, Mauro Giovanni Carta, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Sandro Orrù, Antonella Palimodde, Roberto Perra, Germano Orrù, Maria Conti, Cinzia Balestrieri, Giancarlo Serra, Simona Onali, Francesco Marongiu, Andrea Perra, Luchino Chessa. Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience. Frontiers in Immunology. 2020; 11 ():605688.

Chicago/Turabian Style

Roberto Littera; Marcello Campagna; Silvia Deidda; Goffredo Angioni; Selene Cipri; Maurizio Melis; Davide Firinu; Simonetta Santus; Alberto Lai; Rita Porcella; Sara Lai; Stefania Rassu; Rosetta Scioscia; Federico Meloni; Daniele Schirru; William Cordeddu; Marta Anna Kowalik; Maria Serra; Paola Ragatzu; Mauro Giovanni Carta; Stefano Del Giacco; Angelo Restivo; Simona Deidda; Sandro Orrù; Antonella Palimodde; Roberto Perra; Germano Orrù; Maria Conti; Cinzia Balestrieri; Giancarlo Serra; Simona Onali; Francesco Marongiu; Andrea Perra; Luchino Chessa. 2020. "Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience." Frontiers in Immunology 11, no. : 605688.

Journal article
Published: 25 April 2020 in Environmental Health
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Background Evidence linking risk of lymphoma and B-cell lymphoma subtypes to ionizing radiation is inconclusive, particularly at low exposure levels. Methods We investigated risk of lymphoma (all subtypes), B-cell lymphomas, and its major subtypes, associated with low-level occupational exposure to ionizing radiation, in 2346 lymphoma cases and 2463 controls, who participated in the multicenter EpiLymph case-control study. We developed a job-exposure matrix to estimate exposure to ionizing radiation, distinguishing between internal and external radiation, and we applied it to the lifetime occupational history of study subjects, We calculated the Odds Ratio (OR) and its 95% confidence interval (95% CI) for lymphoma (all subtypes combined), B-cell lymphoma, and its major subtypes using unconditional, polytomous logistic regression adjusting for age, gender, and education. Results We did not observe an association between exposure metrics of external and internal radiation and risk of lymphoma (all subtypes), nor with B-cell lymphoma, or its major subtypes, at the levels regularly experienced in occupational settings. An elevated risk of diffuse large B cell lymphoma was observed among the most likely exposed study subjects with relatively higher exposure intensity, which would be worth further investigation. Conclusions Further investigation is warranted on risk of B cell lymphoma subtypes associated with low-level occupational exposure to external ionizing radiation, and to clarify whether lymphoma should be included among the cancer outcomes related to ionizing radiation.

ACS Style

Giannina Satta; Matteo Loi; Nickolaus Becker; Yolanda Benavente; Silvia De Sanjose; Lenka Foretova; Anthony Staines; Marc Maynadie; Alexandra Nieters; Federico Meloni; Ilaria Pilia; Marcello Campagna; Marco Pau; Lydia B. Zablotska; Pierluigi Cocco. Occupational exposure to ionizing radiation and risk of lymphoma subtypes: results of the Epilymph European case-control study. Environmental Health 2020, 19, 1 -11.

AMA Style

Giannina Satta, Matteo Loi, Nickolaus Becker, Yolanda Benavente, Silvia De Sanjose, Lenka Foretova, Anthony Staines, Marc Maynadie, Alexandra Nieters, Federico Meloni, Ilaria Pilia, Marcello Campagna, Marco Pau, Lydia B. Zablotska, Pierluigi Cocco. Occupational exposure to ionizing radiation and risk of lymphoma subtypes: results of the Epilymph European case-control study. Environmental Health. 2020; 19 (1):1-11.

Chicago/Turabian Style

Giannina Satta; Matteo Loi; Nickolaus Becker; Yolanda Benavente; Silvia De Sanjose; Lenka Foretova; Anthony Staines; Marc Maynadie; Alexandra Nieters; Federico Meloni; Ilaria Pilia; Marcello Campagna; Marco Pau; Lydia B. Zablotska; Pierluigi Cocco. 2020. "Occupational exposure to ionizing radiation and risk of lymphoma subtypes: results of the Epilymph European case-control study." Environmental Health 19, no. 1: 1-11.

Journal article
Published: 08 April 2020 in Sustainability
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The new context of the Psychology of Sustainability and Sustainable Development has reached the attention of the scientific community in recent years, due to its comprehensive approach aimed at enhancing the sustainability of interpersonal and intrapersonal talent, as well as of groups and communities. In this scenario, research on employee cross-cultural adjustment (CCA) is considered a key theme in human resource management. It is known that psychological support in the host country may alleviate distress and facilitate the integration of the expatriate workers. However, there is a lack of research investigating expatriate adjustment as an antecedent of the perceived organizational support. The aim of the study was to investigate the relationship among cross-cultural adjustment (CCA), perception of organizational support (POS), work-related stress (WRS), and innovation, considering these factors as a part of a unique innovative framework. A cross sectional study was performed using a sample of 234 expatriate workers of a multinational organization. Data were collected through a monitoring survey for the assessment of work-related stress risk factors of their expatriate staff. The results showed a positive correlation between CCA, POS, and innovation. On the other hand, a negative correlational effect of CCA and WRS, CCA and POS on WRS, and POS and WRS was found. Finally, POS was found to be a significant antecedent of CCA. These findings have implications for both international human resource management researchers and practitioners.

ACS Style

Gabriele Giorgi; Luigi Isaia Lecca; Antonio Ariza-Montes; Chiara Di Massimo; Marcello Campagna; Georgia Libera Finstad; Giulio Arcangeli; Nicola Mucci. The Dark and the Light Side of the Expatriate’s Cross-Cultural Adjustment: A Novel Framework Including Perceived Organizational Support, Work Related Stress and Innovation. Sustainability 2020, 12, 2969 .

AMA Style

Gabriele Giorgi, Luigi Isaia Lecca, Antonio Ariza-Montes, Chiara Di Massimo, Marcello Campagna, Georgia Libera Finstad, Giulio Arcangeli, Nicola Mucci. The Dark and the Light Side of the Expatriate’s Cross-Cultural Adjustment: A Novel Framework Including Perceived Organizational Support, Work Related Stress and Innovation. Sustainability. 2020; 12 (7):2969.

Chicago/Turabian Style

Gabriele Giorgi; Luigi Isaia Lecca; Antonio Ariza-Montes; Chiara Di Massimo; Marcello Campagna; Georgia Libera Finstad; Giulio Arcangeli; Nicola Mucci. 2020. "The Dark and the Light Side of the Expatriate’s Cross-Cultural Adjustment: A Novel Framework Including Perceived Organizational Support, Work Related Stress and Innovation." Sustainability 12, no. 7: 2969.

Journal article
Published: 25 February 2020 in BMC Palliative Care
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Background Hospice workers are required to regularly use emotional regulation strategies in an attempt to encourage and sustain terminally ill patients and families. Daily emotional regulation in reaction to constantly watching suffering patients may be intensified among those hospice professionals who have high levels of compassion fatigue. The main object of this study was to examine the relationship between daily exposition to seeing patient suffering and daily emotional work, and to assess whether compassion fatigue (secondary traumatic stress and burnout) buffers this relationship. Methods We used a diary research design for collecting daily fluctuations in seeing patients suffering and emotional work display. Participants filled in a general survey and daily survey over a period of eight consecutive workdays. A total of 39 hospice professionals from two Italian hospices participated in the study. Results Multilevel analyses demonstrated that daily fluctuations in seeing patients suffering was positively related to daily emotional work display after controlling for daily death of patients. Moreover, considering previous levels of compassion fatigue, a buffering effect of high burnout on seeing patients suffering - daily emotional work display relationship was found. Conclusions A central finding of our study is that fluctuations in daily witness of patients suffering are positively related to daily use of positive emotional regulations. Further, our results show that burnout buffers this relationship such that hospice professionals with high burnout use more emotional display in days where they recurrently witness patients suffering.

ACS Style

Igor Portoghese; Maura Galletta; Philip Larkin; Salvatore Sardo; Marcello Campagna; Gabriele Finco; Ernesto D’Aloja. Compassion fatigue, watching patients suffering and emotional display rules among hospice professionals: a daily diary study. BMC Palliative Care 2020, 19, 1 -7.

AMA Style

Igor Portoghese, Maura Galletta, Philip Larkin, Salvatore Sardo, Marcello Campagna, Gabriele Finco, Ernesto D’Aloja. Compassion fatigue, watching patients suffering and emotional display rules among hospice professionals: a daily diary study. BMC Palliative Care. 2020; 19 (1):1-7.

Chicago/Turabian Style

Igor Portoghese; Maura Galletta; Philip Larkin; Salvatore Sardo; Marcello Campagna; Gabriele Finco; Ernesto D’Aloja. 2020. "Compassion fatigue, watching patients suffering and emotional display rules among hospice professionals: a daily diary study." BMC Palliative Care 19, no. 1: 1-7.

Journal article
Published: 25 February 2020
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ACS Style

Luigi I Lecca; Daniele Fabbri; Igor Portoghese; Ilaria Pilia; Federico Meloni; Gabriele Marcias; Maura Galletta; Nicola Mucci; Marcello Campagna; Marco Monticone. Manual handling of patients: role of kinesiophobia and catastrophising on health workers with chronic low back pain. A cross-sectional observational study. 2020, 1 .

AMA Style

Luigi I Lecca, Daniele Fabbri, Igor Portoghese, Ilaria Pilia, Federico Meloni, Gabriele Marcias, Maura Galletta, Nicola Mucci, Marcello Campagna, Marco Monticone. Manual handling of patients: role of kinesiophobia and catastrophising on health workers with chronic low back pain. A cross-sectional observational study. . 2020; ():1.

Chicago/Turabian Style

Luigi I Lecca; Daniele Fabbri; Igor Portoghese; Ilaria Pilia; Federico Meloni; Gabriele Marcias; Maura Galletta; Nicola Mucci; Marcello Campagna; Marco Monticone. 2020. "Manual handling of patients: role of kinesiophobia and catastrophising on health workers with chronic low back pain. A cross-sectional observational study." , no. : 1.

Commentary
Published: 04 February 2020 in Cancers
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Breast cancer is one of the most common diseases worldwide, mainly affecting the female gender. Considering the increase of breast cancer incidence and the decrease of mortality due to news diagnostic and therapeutic tools, the return to work issue after treatment is going to be very common in the next years. Occupational physicians therefore need to face the return to work and the fitness for work of workers previously diagnosed with breast cancer with a sufficient cultural and technical background. In addition to individual characteristics preceding the diagnosis, clinical outcome, lifestyles and occupational variables are the most impactful factors on return to work that need to be taken into account. The aim of this work is to analyze these factors and discuss the central role of occupational physicians in the decision-making process of returning to work in breast cancer survivors.

ACS Style

Marcello Campagna; Roberto Loscerbo; Ilaria Pilia; Federico Meloni. Return to Work of Breast Cancer Survivors: Perspectives and Challenges for Occupational Physicians. Cancers 2020, 12, 355 .

AMA Style

Marcello Campagna, Roberto Loscerbo, Ilaria Pilia, Federico Meloni. Return to Work of Breast Cancer Survivors: Perspectives and Challenges for Occupational Physicians. Cancers. 2020; 12 (2):355.

Chicago/Turabian Style

Marcello Campagna; Roberto Loscerbo; Ilaria Pilia; Federico Meloni. 2020. "Return to Work of Breast Cancer Survivors: Perspectives and Challenges for Occupational Physicians." Cancers 12, no. 2: 355.

Reply
Published: 14 January 2020 in International Journal of Environmental Research and Public Health
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We appreciate the interest raised by our paper on the association between conditions linked to work-related stress and the prolongation of the QT interval on the electrocardiogram [...].

ACS Style

Luigi Isaia Lecca; Igor Portoghese; Nicola Mucci; Maura Galletta; Federico Meloni; Ilaria Pilia; Gabriele Marcias; Daniele Fabbri; Jacopo Fostinelli; Roberto G. Lucchini; Pierluigi Cocco; Marcello Campagna. Reply to Comment on Lecca, L.I.; Portoghese, I.; Mucci, N.; Galletta, M.; Meloni, F.; Pilia, I.; Marcias, G.; Fabbri, D.; Fostinelli, J.; Lucchini, R.G.; Cocco, P.; Campagna, M. Association between Work-Related Stress and QT Prolongation in Male Workers. International Journal of Environmental Research and Public Health 2020, 17, 510 .

AMA Style

Luigi Isaia Lecca, Igor Portoghese, Nicola Mucci, Maura Galletta, Federico Meloni, Ilaria Pilia, Gabriele Marcias, Daniele Fabbri, Jacopo Fostinelli, Roberto G. Lucchini, Pierluigi Cocco, Marcello Campagna. Reply to Comment on Lecca, L.I.; Portoghese, I.; Mucci, N.; Galletta, M.; Meloni, F.; Pilia, I.; Marcias, G.; Fabbri, D.; Fostinelli, J.; Lucchini, R.G.; Cocco, P.; Campagna, M. Association between Work-Related Stress and QT Prolongation in Male Workers. International Journal of Environmental Research and Public Health. 2020; 17 (2):510.

Chicago/Turabian Style

Luigi Isaia Lecca; Igor Portoghese; Nicola Mucci; Maura Galletta; Federico Meloni; Ilaria Pilia; Gabriele Marcias; Daniele Fabbri; Jacopo Fostinelli; Roberto G. Lucchini; Pierluigi Cocco; Marcello Campagna. 2020. "Reply to Comment on Lecca, L.I.; Portoghese, I.; Mucci, N.; Galletta, M.; Meloni, F.; Pilia, I.; Marcias, G.; Fabbri, D.; Fostinelli, J.; Lucchini, R.G.; Cocco, P.; Campagna, M. Association between Work-Related Stress and QT Prolongation in Male Workers." International Journal of Environmental Research and Public Health 17, no. 2: 510.

Journal article
Published: 19 December 2019 in International Journal of Environmental Research and Public Health
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Background: In spite of the reduced exposure level, and its ban in numerous countries, compensation claims for asbestos-related diseases are far from decreasing. Methods: We used retrospective exposure assessment techniques to explore respiratory function and a computerized tomography (CT) scan in relation to past asbestos exposure in 115 male workers retired from an acrylic and polyester fiber plant. Based, on detailed information on exposure circumstances, we reconstructed a cumulative exposure estimate for each patient. Results: Time-weighted average exposure in our study population was 0.24 fibers/ml (95% confidence inteval (CI) 0.19–0.29), and the average cumulative exposure was 4.51 fibers/mL-years (95% CI 3.95–5.07). Exposure was elevated among maintenance workers, compared to other jobs (p = 0.00001). Respiratory function parameters did not vary in relation to the exposure estimates, nor to CT scan results. Risk of interstitial fibrosis showed a significant upward trend (Wald test for trend = 2.62, p = 0.009) with cumulative exposure to asbestos; risk associated with 5.26 fibers/mL-years or more, was 8-fold (95% CI 1.18–54.5). Conclusions: Our results suggest that a CT scan can detect pleuro-parenchymal lung alterations at asbestos exposure levels lower than previously thought, in absence of respiratory impairment. Further studies are required to validate our techniques of retrospective assessment of asbestos exposure.

ACS Style

Giannina Satta; Tiziana Serra; Federico Meloni; Achille Lazzarato; Alessandra Argiolas; Elisa Bosu; Antonella Coratza; Nicola Frau; Michele Lai; Luigi Isaia Lecca; Nicola Mascia; Ilaria Pilia; Veronica Piras; Giovanni Sferlazzo; Marcello Campagna; Pierluigi Cocco. Pulmonary Function and CT Scan Imaging at Low-Level Occupational Exposureto Asbestos. International Journal of Environmental Research and Public Health 2019, 17, 50 .

AMA Style

Giannina Satta, Tiziana Serra, Federico Meloni, Achille Lazzarato, Alessandra Argiolas, Elisa Bosu, Antonella Coratza, Nicola Frau, Michele Lai, Luigi Isaia Lecca, Nicola Mascia, Ilaria Pilia, Veronica Piras, Giovanni Sferlazzo, Marcello Campagna, Pierluigi Cocco. Pulmonary Function and CT Scan Imaging at Low-Level Occupational Exposureto Asbestos. International Journal of Environmental Research and Public Health. 2019; 17 (1):50.

Chicago/Turabian Style

Giannina Satta; Tiziana Serra; Federico Meloni; Achille Lazzarato; Alessandra Argiolas; Elisa Bosu; Antonella Coratza; Nicola Frau; Michele Lai; Luigi Isaia Lecca; Nicola Mascia; Ilaria Pilia; Veronica Piras; Giovanni Sferlazzo; Marcello Campagna; Pierluigi Cocco. 2019. "Pulmonary Function and CT Scan Imaging at Low-Level Occupational Exposureto Asbestos." International Journal of Environmental Research and Public Health 17, no. 1: 50.

Journal article
Published: 28 November 2019 in International Journal of Environmental Research and Public Health
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: Background: Work-related stress is a potential cardiovascular risk factor, but the underlying mechanism is not fully explained. The autonomic nervous system control of cardiac function might play a specific role; therefore, monitoring the QT interval in the electrocardiogram can highlight an autonomic imbalance induced by occupational stressors. The aim of our study was to explore the QT interval parameters as early indicators of imbalance of the autonomic cardiac function in relation to work-related stress. Methods: During 2015–2016 annual workplace health surveillance, we measured work-related stress in 484 workers of a logistic support company using the Health and Safety Executive (HSE) tool. We assessed the frequency-corrected QT (QTc) interval and the QT index (QTi) on the electrocardiogram of each participant, and collected demographic and clinical data. We compared the QTc values by the four Karasek’s categories (active/passive jobs, low/high strain job), and by job support (present/lacking), and conducted multivariate analysis to adjust for possible confounders. Results: The results of the multivariate regression analysis showed that QTc was prolonged among workers operating at a specific site where stress level was found to be elevated. Regular physical activity showed a beneficial effect against QTc prolongation. We did not observe an effect on QTc length by the cross-combined Karasek’s categories of job control, job demand, and job support. Conclusions: Our study suggests subclinical effects of conditions associated with work-related stress on the autonomic regulation of cardiac function. Further research is warranted to elucidate the combined effect of work organization and lifestyle factors on autonomic cardiac function.

ACS Style

Luigi Isaia Lecca; Igor Portoghese; Nicola Mucci; Maura Galletta; Federico Meloni; Ilaria Pilia; Gabriele Marcias; Daniele Fabbri; Jacopo Fostinelli; Roberto G. Lucchini; Pierluigi Cocco; Marcello Campagna. Association between Work-Related Stress and QT Prolongation in Male Workers. International Journal of Environmental Research and Public Health 2019, 16, 4781 .

AMA Style

Luigi Isaia Lecca, Igor Portoghese, Nicola Mucci, Maura Galletta, Federico Meloni, Ilaria Pilia, Gabriele Marcias, Daniele Fabbri, Jacopo Fostinelli, Roberto G. Lucchini, Pierluigi Cocco, Marcello Campagna. Association between Work-Related Stress and QT Prolongation in Male Workers. International Journal of Environmental Research and Public Health. 2019; 16 (23):4781.

Chicago/Turabian Style

Luigi Isaia Lecca; Igor Portoghese; Nicola Mucci; Maura Galletta; Federico Meloni; Ilaria Pilia; Gabriele Marcias; Daniele Fabbri; Jacopo Fostinelli; Roberto G. Lucchini; Pierluigi Cocco; Marcello Campagna. 2019. "Association between Work-Related Stress and QT Prolongation in Male Workers." International Journal of Environmental Research and Public Health 16, no. 23: 4781.

Journal article
Published: 15 March 2019 in Environments
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The occupational exposure to airborne fine and ultrafine particles (UFPs) and noise in aircraft personnel employed in airport taxiway was investigated. Stationary samplings and multiple personal sampling sites and job tasks were considered. Size distribution, particle number concentrations, lung dose surface area were measured by personal particle counters and by means of an electric low pressure impactor (ELPI+TM). Morphological and chemical characterization of UFPs were performed by transmission and scanning electron microscopy, the latter together with energy dispersive X-Ray spectroscopy based spatially resolved compositional mapping. A-weighted noise exposure level A-weighted noise exposure level normalized to an 8 h working day and Peak Sound C-weighted Pressure Level was calculated for single worker and for homogeneous exposure groups. Our study provides evidence on the impact of aviation-related emissions on occupational exposure to ultrafine particles and noise exposure of workers operating in an airport taxiway. Main exposure peaks are related to pre-flight operations of engine aircrafts. Although exposure to ultrafine particles and noise appears to not be critical if compared with other occupational scenarios, the coincidence in time of high peaks of exposure to ultrafine particles and noise suggest that further investigations are warranted in order to assess possible subclinical and clinical adverse health effects in exposed workers, especially for cardiovascular apparatus.

ACS Style

Gabriele Marcias; Maria Francesca Casula; Michele Uras; Andrea Falqui; Edoardo Miozzi; Elisa Sogne; Sergio Pili; Ilaria Pilia; Daniele Fabbri; Federico Meloni; Marco Pau; Andrea Maurizio Sanna; Jacopo Fostinelli; Giorgio Massacci; Ernesto D’Aloja; Francesca Larese Filon; Marcello Campagna; Luigi Isaia Lecca. Occupational Fine/Ultrafine Particles and Noise Exposure in Aircraft Personnel Operating in Airport Taxiway. Environments 2019, 6, 35 .

AMA Style

Gabriele Marcias, Maria Francesca Casula, Michele Uras, Andrea Falqui, Edoardo Miozzi, Elisa Sogne, Sergio Pili, Ilaria Pilia, Daniele Fabbri, Federico Meloni, Marco Pau, Andrea Maurizio Sanna, Jacopo Fostinelli, Giorgio Massacci, Ernesto D’Aloja, Francesca Larese Filon, Marcello Campagna, Luigi Isaia Lecca. Occupational Fine/Ultrafine Particles and Noise Exposure in Aircraft Personnel Operating in Airport Taxiway. Environments. 2019; 6 (3):35.

Chicago/Turabian Style

Gabriele Marcias; Maria Francesca Casula; Michele Uras; Andrea Falqui; Edoardo Miozzi; Elisa Sogne; Sergio Pili; Ilaria Pilia; Daniele Fabbri; Federico Meloni; Marco Pau; Andrea Maurizio Sanna; Jacopo Fostinelli; Giorgio Massacci; Ernesto D’Aloja; Francesca Larese Filon; Marcello Campagna; Luigi Isaia Lecca. 2019. "Occupational Fine/Ultrafine Particles and Noise Exposure in Aircraft Personnel Operating in Airport Taxiway." Environments 6, no. 3: 35.

Journal article
Published: 18 February 2019 in BMC Nursing
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Work–family conflict (WFC) is a crucial problem in nursing because of the demanding conditions of the job, such as strenuous shifts, physical and emotional workload, and intense patient involvement. Using a multilevel approach, this study investigated the moderating role of collective affective commitment as a protective resource in the relationship between WFC and emotional exhaustion. The sample included 647 nurses from 66 working units in 4 Italian hospitals. A self-administrated questionnaire was administered to nurses. To analyze data, hierarchical linear modeling was used to examine cross-level relationships between variables. The results indicated that emotional exhaustion increased with augmenting of WFC and that this relationship was stronger when collective affective commitment was low and weaker when it was high. The study thus suggests that collective affective commitment may be considered a protective resource for nurses. Moreover, the results show that high work–family conflict should not represent a serious problem when nurses have high affective commitment. Interventions at both individual and group level are discussed in order to mitigate WFC, promoting collective affective commitment and thus reducing emotional exhaustion.

ACS Style

Maura Galletta; Igor Portoghese; Paola Melis; Cesar Ivan Aviles Gonzalez; Gabriele Finco; Ernesto D’Aloja; Paolo Contu; Marcello Campagna. The role of collective affective commitment in the relationship between work–family conflict and emotional exhaustion among nurses: a multilevel modeling approach. BMC Nursing 2019, 18, 1 -9.

AMA Style

Maura Galletta, Igor Portoghese, Paola Melis, Cesar Ivan Aviles Gonzalez, Gabriele Finco, Ernesto D’Aloja, Paolo Contu, Marcello Campagna. The role of collective affective commitment in the relationship between work–family conflict and emotional exhaustion among nurses: a multilevel modeling approach. BMC Nursing. 2019; 18 (1):1-9.

Chicago/Turabian Style

Maura Galletta; Igor Portoghese; Paola Melis; Cesar Ivan Aviles Gonzalez; Gabriele Finco; Ernesto D’Aloja; Paolo Contu; Marcello Campagna. 2019. "The role of collective affective commitment in the relationship between work–family conflict and emotional exhaustion among nurses: a multilevel modeling approach." BMC Nursing 18, no. 1: 1-9.

Journal article
Published: 01 February 2019 in Metals
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Several studies have shown an increased mortality rate for different types of tumors, respiratory disease and cardiovascular morbidity associated with foundry work. Airborne particles were investigated in a steelmaking foundry using an electric low-pressure impactor (ELPI+™), a Philips Aerasense Nanotracer and traditional sampling equipment. Determination of metallic elements in the collected particles was carried out by inductively coupled plasma mass spectrometry. The median of ultrafine particle (UFP) concentration was between 4.91 × 103 and 2.33 × 105 part/cm3 (max. 9.48 × 106 part/cm3). Background levels ranged from 1.97 × 104 to 3.83 × 104 part/cm3. Alveolar and deposited tracheobronchial surface area doses ranged from 1.3 × 102 to 8.7 × 103 mm2, and 2.6 × 101 to 1.3 × 103 mm2, respectively. Resulting inhalable and respirable fraction and metallic elements were below limit values set by Italian legislation. A variable concentration of metallic elements was detected in the different fractions of UFPs in relation to the sampling site, the emission source and the size range. This data could be useful in order to increase the knowledge about occupational exposure to fine and ultrafine particles and to design studies aimed to investigate early biological effects associated with the exposure to particulate matter in the foundry industries.

ACS Style

Gabriele Marcias; Jacopo Fostinelli; Andrea Maurizio Sanna; Michele Uras; Simona Catalani; Sergio Pili; Daniele Fabbri; Ilaria Pilia; Federico Meloni; Luigi Isaia Lecca; Egidio Madeo; Giorgio Massacci; Luca Stabile; Ernesto D’Aloja; Giorgio Buonanno; Giuseppe De Palma; Marcello Campagna. Occupational Exposure to Fine Particles and Ultrafine Particles in a Steelmaking Foundry. Metals 2019, 9, 163 .

AMA Style

Gabriele Marcias, Jacopo Fostinelli, Andrea Maurizio Sanna, Michele Uras, Simona Catalani, Sergio Pili, Daniele Fabbri, Ilaria Pilia, Federico Meloni, Luigi Isaia Lecca, Egidio Madeo, Giorgio Massacci, Luca Stabile, Ernesto D’Aloja, Giorgio Buonanno, Giuseppe De Palma, Marcello Campagna. Occupational Exposure to Fine Particles and Ultrafine Particles in a Steelmaking Foundry. Metals. 2019; 9 (2):163.

Chicago/Turabian Style

Gabriele Marcias; Jacopo Fostinelli; Andrea Maurizio Sanna; Michele Uras; Simona Catalani; Sergio Pili; Daniele Fabbri; Ilaria Pilia; Federico Meloni; Luigi Isaia Lecca; Egidio Madeo; Giorgio Massacci; Luca Stabile; Ernesto D’Aloja; Giorgio Buonanno; Giuseppe De Palma; Marcello Campagna. 2019. "Occupational Exposure to Fine Particles and Ultrafine Particles in a Steelmaking Foundry." Metals 9, no. 2: 163.

Observational study
Published: 07 September 2018 in International Journal of Environmental Research and Public Health
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Work-related stress is a known occupational hazard, with a putative role on the development of cardiovascular diseases (CVD). Although several investigations have explored the association in various workplace scenarios, none have focused on the airport flight logistic support personnel, a transportation business of crucial importance, potentially exposed to job stress and consequently to an increase in CVD risk. We explored the relationship between work-related stress and cardiovascular risk in 568 healthy workers of a flight logistic support company using the Health and Safety Executive questionnaire, the Framingham Heart Study General Cardiovascular Disease (CVD) Risk Prediction Score, and the WHO general well-being index (WHO-5). We used univariate and multivariate statistical methods to take account of possible confounders. Our results show that a low job support significantly increases the CVD risk score and decreases the WHO well-being index with reference to subjects reporting high support on the job. In addition, the well-being index of workers with high strain jobs appears lower in respect to workers employed in low strain job. The multivariate analysis confirms a protective effect of job support, and shows a detrimental influence on CVD risk by physical inactivity, regular intake of alcohol, and a low educational level. In addition, job control, job support, low strain, and high demand coupled with high control (active job) showed a beneficial effect on psychological well-being. Our results suggest that a combination of general risk factors and organizational factors contributes to increase CVD risk and well-being, representing a crucial target for intervention strategies to promote health in the workplace.

ACS Style

Luigi Isaia Lecca; Marcello Campagna; Igor Portoghese; Maura Galletta; Nicola Mucci; Michele Meloni; Pierluigi Cocco. Work Related Stress, Well-Being and Cardiovascular Risk among Flight Logistic Workers: An Observational Study. International Journal of Environmental Research and Public Health 2018, 15, 1952 .

AMA Style

Luigi Isaia Lecca, Marcello Campagna, Igor Portoghese, Maura Galletta, Nicola Mucci, Michele Meloni, Pierluigi Cocco. Work Related Stress, Well-Being and Cardiovascular Risk among Flight Logistic Workers: An Observational Study. International Journal of Environmental Research and Public Health. 2018; 15 (9):1952.

Chicago/Turabian Style

Luigi Isaia Lecca; Marcello Campagna; Igor Portoghese; Maura Galletta; Nicola Mucci; Michele Meloni; Pierluigi Cocco. 2018. "Work Related Stress, Well-Being and Cardiovascular Risk among Flight Logistic Workers: An Observational Study." International Journal of Environmental Research and Public Health 15, no. 9: 1952.

Journal article
Published: 26 July 2018 in Molecules
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High-throughput screening of samples is the strategy of choice to detect occupational exposure biomarkers, yet it requires a user-friendly apparatus that gives relatively prompt results while ensuring high degrees of selectivity, precision, accuracy and automation, particularly in the preparation process. Miniaturization has attracted much attention in analytical chemistry and has driven solvent and sample savings as easier automation, the latter thanks to the introduction on the market of the three axis autosampler. In light of the above, this contribution describes a novel user-friendly solid-phase microextraction (SPME) off- and on-line platform coupled with gas chromatography and triple quadrupole-mass spectrometry to determine urinary metabolites of polycyclic aromatic hydrocarbons 1- and 2-hydroxy-naphthalene, 9-hydroxy-phenanthrene, 1-hydroxy-pyrene, 3- and 9-hydroxy-benzoantracene, and 3-hydroxy-benzo[a]pyrene. In this new procedure, chromatography’s sensitivity is combined with the user-friendliness of N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide on-fiber SPME derivatization using direct immersion sampling; moreover, specific isotope-labelled internal standards provide quantitative accuracy. The detection limits for the seven OH-PAHs ranged from 0.25 to 4.52 ng/L. Intra-(from 2.5 to 3.0%) and inter-session (from 2.4 to 3.9%) repeatability was also evaluated. This method serves to identify suitable risk-control strategies for occupational hygiene conservation programs.

ACS Style

Stefano Dugheri; Alessandro Bonari; Matteo Gentili; Giovanni Cappelli; Ilenia Pompilio; Costanza Bossi; Giulio Arcangeli; Marcello Campagna; Nicola Mucci. High-Throughput Analysis of Selected Urinary Hydroxy Polycyclic Aromatic Hydrocarbons by an Innovative Automated Solid-Phase Microextraction. Molecules 2018, 23, 1869 .

AMA Style

Stefano Dugheri, Alessandro Bonari, Matteo Gentili, Giovanni Cappelli, Ilenia Pompilio, Costanza Bossi, Giulio Arcangeli, Marcello Campagna, Nicola Mucci. High-Throughput Analysis of Selected Urinary Hydroxy Polycyclic Aromatic Hydrocarbons by an Innovative Automated Solid-Phase Microextraction. Molecules. 2018; 23 (8):1869.

Chicago/Turabian Style

Stefano Dugheri; Alessandro Bonari; Matteo Gentili; Giovanni Cappelli; Ilenia Pompilio; Costanza Bossi; Giulio Arcangeli; Marcello Campagna; Nicola Mucci. 2018. "High-Throughput Analysis of Selected Urinary Hydroxy Polycyclic Aromatic Hydrocarbons by an Innovative Automated Solid-Phase Microextraction." Molecules 23, no. 8: 1869.

Journal article
Published: 07 June 2018 in International Journal of Environmental Research and Public Health
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Background: The characteristics of aerosol, in particular particle size and chemical composition, can have an impact on human health. Particle size distribution and chemical composition is a necessary parameter in occupational exposure assessment conducted in order to understand possible health effects. The aim of this study was to characterize workplace airborne particulate matter in a metallurgical setting by synergistically using two different approaches; Methodology: Analysis of inhalable fraction concentrations through traditional sampling equipment and ultrafine particles (UFP) concentrations and size distribution was conducted by an Electric Low-Pressure Impactor (ELPI+™). The determination of metallic elements (ME) in particles was carried out by inductively coupled plasma mass spectrometry; Results: Inhalable fraction and ME concentrations were below the limits set by Italian legislation and the American Conference of Governmental Industrial Hygienists (ACGIH, 2017). The median of UFP was between 4.00 × 104 and 2.92 × 105 particles/cm3. ME concentrations determined in the particles collected by ELPI show differences in size range distribution; Conclusions: The adopted synergistic approach enabled a qualitative and quantitative assessment of the particles in steelmaking factories. The results could lead to a better knowledge of occupational exposure characterization, in turn affording a better understanding of occupational health issues due to metal fumes exposure.

ACS Style

Gabriele Marcias; Jacopo Fostinelli; Simona Catalani; Michele Uras; Andrea Maurizio Sanna; Giuseppe Avataneo; Giuseppe De Palma; Daniele Fabbri; Matteo Paganelli; Luigi Isaia Lecca; Giorgio Buonanno; Marcello Campagna. Composition of Metallic Elements and Size Distribution of Fine and Ultrafine Particles in a Steelmaking Factory. International Journal of Environmental Research and Public Health 2018, 15, 1192 .

AMA Style

Gabriele Marcias, Jacopo Fostinelli, Simona Catalani, Michele Uras, Andrea Maurizio Sanna, Giuseppe Avataneo, Giuseppe De Palma, Daniele Fabbri, Matteo Paganelli, Luigi Isaia Lecca, Giorgio Buonanno, Marcello Campagna. Composition of Metallic Elements and Size Distribution of Fine and Ultrafine Particles in a Steelmaking Factory. International Journal of Environmental Research and Public Health. 2018; 15 (6):1192.

Chicago/Turabian Style

Gabriele Marcias; Jacopo Fostinelli; Simona Catalani; Michele Uras; Andrea Maurizio Sanna; Giuseppe Avataneo; Giuseppe De Palma; Daniele Fabbri; Matteo Paganelli; Luigi Isaia Lecca; Giorgio Buonanno; Marcello Campagna. 2018. "Composition of Metallic Elements and Size Distribution of Fine and Ultrafine Particles in a Steelmaking Factory." International Journal of Environmental Research and Public Health 15, no. 6: 1192.