Cristina Grippaudo

Prof. Dr. Cristina Grippaudo

Head, neck and sensory organs, Università Cattolica del Sacro Cuore, Rome, Lazio, Italy
orcid

Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 October 2016 in Acta Otorhinolaryngologica Italica
Verified
Journal Article
Open access
Cristina GrippaudoCristina Grippaudo
Cristina Grippaudo
EPE.G. Paolantonio
E.G. Paolantonio
GAG. Antonini
G. Antonini
RSR. Saulle
R. Saulle
Giuseppe La TorreGiuseppe La Torre
Giuseppe La Torre
RDR. Deli
R. Deli
Il rapporto fra abitudini viziate, respirazione orale e malocclusione è fondamentale in tema di prevenzione e trattamento precoce dei disturbi della crescita cranio-facciale. Infatti così come le abitudini viziate possono interferire negativamente con la posizione dei denti e con il normale pattern di crescita scheletrica cranio-facciale, così l’ostruzione delle vie aeree superiori, con conseguente respirazione orale, cambia il modello di crescita craniofacciale con sviluppo di malocclusioni da moderate a severe. Questo studio trasversale, effettuato su 3.017 bambini applicando il ROMA index, vuole verificare l’esistenza di una correlazione significativa tra abitudini viziate/respirazione orale e malocclusione. Dai risultati emerge che all’aumentare del grado dell’indice aumenta anche la prevalenza di abitudini viziate e respirazione orale, significando che questi fattori sono associati alle malocclusioni più gravi. Inoltre abbiamo riscontrato un’associazione statisticamente significativa fra abitudini viziate e overjet e openbite aumentati, ma non con il morso inverso. Dal lavoro è emerso che la respirazione orale è strettamente correlata ad overjet aumentato, overjet inverso, morso crociato, openbite e displacement. Riteniamo quindi che abitudini viziate e respirazione orale, rientrando fra i fattori di rischio di malocclusione, vadano intercettati e corretti precocemente per prevenire lo sviluppo di malocclusioni o il peggioramento di quelle preesistenti.

21 April 2023 in Pharmaceutics
Verified
Journal Article
Open access
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MAMariacristina Amato
Mariacristina Amato
SSSimona Santonocito
Simona Santonocito
Alessandro PolizziAlessandro Polizzi
Alessandro Polizzi
Gianluca TartagliaGianluca Tartaglia
Gianluca Tartaglia
VRVincenzo Ronsivalle
Vincenzo Ronsivalle
Gaetano IsolaGaetano Isola
Gaetano Isola
Periodontitis is an inflammatory disease of the gums characterized by the degeneration of periodontal ligaments, the formation of periodontal pockets, and the resorption of the alveolar bone, which results in the destruction of the teeth’s supporting structure. Periodontitis is caused by the growth of diverse microflora (particularly anaerobes) in the pockets, releasing toxins and enzymes and stimulating the immune system. Various approaches, both local and systemic, have been used to treat periodontitis effectively. Successful treatment depends on reducing bacterial biofilm, bleeding on probing (BOP), and reducing or eliminating pockets. Currently, the use of local drug delivery systems (LDDSs) as an adjunctive therapy to scaling and root planing (SRP) in periodontitis is a promising strategy, resulting in greater efficacy and fewer adverse effects by controlling drug release. Selecting an appropriate bioactive agent and route of administration is the cornerstone of a successful periodontitis treatment plan. In this context, this review focuses on applications of LDDSs with varying properties in treating periodontitis with or without systemic diseases to identify current challenges and future research directions.

1 January 2022 in BioMed Research International
Verified
Journal Article
Open access
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Sabina SaccomannoSabina Saccomanno
Sabina Saccomanno
SSStefano Saran
Stefano Saran
DLD. Laganà
D. Laganà
RMRodolfo Francesco Mastrapasqua
Rodolfo Francesco Mastrapasqua
Cristina GrippaudoCristina Grippaudo
Cristina Grippaudo
Purpose. The article is aimed at improving the understanding of the sociocultural profile of adult orthodontic patients and their expectations. In particular, it addresses three main aspects: the motivation and needs that underpin the decision to start orthodontic treatment, how it influences the patients’ daily life, and the different oral hygiene demands. Materials and Methods. An online survey was completed by 276 patients undergoing orthodontic treatment with different techniques. The questions asked concerned gender, age, type of appliance, any previous orthodontic treatments, type of any previous retainers, reasons for therapy, satisfaction, pain, problems in eating, daily number of teeth brushings and flossings before and during the treatment, perception of cost, sensation of visibility of the appliance, and if they would recommend orthodontic treatment. Results. A significant role within our sample is played by gender; 87.94% consisted of female patients out of which 72.57% wanted to improve their aesthetics, while only 54.84% of male patients cited the same reason. Invisible aligners were preferred by 67.70% of the patients due to them being considered the least painful, causing the fewest problems with eating, and the least visible. Metal braces were perceived as the less expensive treatment. Over a third of the patients (33.85%) had previously undergone orthodontic treatment, among them 54.05% wore a mobile retainer, 31.08% a fixed one, and 14.86% both. Daily tooth brushing and flossing increased during therapy with clear aligners by 48.94% and 126.39%, respectively. Conclusions. The greatest demand for orthodontic treatments comes from women, as they pay more attention to aesthetics, which makes the clear aligners the most common choice. The relapse after orthodontic treatment seems to cause a higher demand for retreatment, and oral hygiene habits significantly improve during orthodontic treatment, especially with the clear aligners.

21 June 2020 in Materials
Verified
Journal Article
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Antonino Lo GiudiceAntonino Lo Giudice
Antonino Lo Giudice
VRVincenzo Ronsivalle
Vincenzo Ronsivalle
Cristina GrippaudoCristina Grippaudo
Cristina Grippaudo
Alessandra LuccheseAlessandra Lucchese
Alessandra Lucchese
SMSimone Muraglie
Simone Muraglie
Gaetano IsolaGaetano Isola
Gaetano Isola
The accuracy of 3D reconstructions of the craniomaxillofacial region using cone beam computed tomography (CBCT) is important for the morphological evaluation of specific anatomical structures. Moreover, an accurate segmentation process is fundamental for the physical reconstruction of the anatomy (3D printing) when a preliminary simulation of the therapy is required. In this regard, the objective of this study is to evaluate the accuracy of four different types of software for the semiautomatic segmentation of the mandibular jaw compared to manual segmentation, used as a gold standard. Twenty cone beam computed tomography (CBCT) with a manual approach (Mimics) and a semi-automatic approach (Invesalius, ITK-Snap, Dolphin 3D, Slicer 3D) were selected for the segmentation of the mandible in the present study. The accuracy of semi-automatic segmentation was evaluated: (1) by comparing the mandibular volumes obtained with semi-automatic 3D rendering and manual segmentation and (2) by deviation analysis between the two mandibular models. An analysis of variance (ANOVA) was used to evaluate differences in mandibular volumetric recordings and for a deviation analysis among the different software types used. Linear regression was also performed between manual and semi-automatic methods. No significant differences were found in the total volumes among the obtained 3D mandibular models (Mimics = 40.85 cm3, ITK-Snap = 40.81 cm3, Invesalius = 40.04 cm3, Dolphin 3D = 42.03 cm3, Slicer 3D = 40.58 cm3). High correlations were found between the semi-automatic segmentation and manual segmentation approach, with R coefficients ranging from 0,960 to 0,992. According to the deviation analysis, the mandibular models obtained with ITK-Snap showed the highest matching percentage (Tolerance A = 88.44%, Tolerance B = 97.30%), while those obtained with Dolphin 3D showed the lowest matching percentage (Tolerance A = 60.01%, Tolerance B = 87.76%) (p < 0.05). Colour-coded maps showed that the area of greatest mismatch between semi-automatic and manual segmentation was the condylar region and the region proximate to the dental roots. Despite the fact that the semi-automatic segmentation of the mandible showed, in general, high reliability and high correlation with the manual segmentation, caution should be taken when evaluating the morphological and dimensional characteristics of the condyles either on CBCT-derived digital models or physical models (3D printing).

7 November 2013 in Progress in Orthodontics
Verified
Journal Article
Open access
PDF file
Cristina GrippaudoCristina Grippaudo
Cristina Grippaudo
BOBruno Oliva
Bruno Oliva
AGAnna Lucia Greco
Anna Lucia Greco
SSSimone Sferra
Simone Sferra
RDRoberto Deli
Roberto Deli
The purpose of this study is to evaluate the relationship between dental arch form and the vertical facial pattern determined by the angle between the mandibular plane and the anterior cranial base (Sella-nasion/mandibular plane angle (SN-MP)) in skeletal class II untreated patients.

1 July 2019 in International Journal of Oral and Maxillofacial Surgery
Verified
Journal Article
Closed access
DSD. Soverina
D. Soverina
GGGiulio Gasparini
Giulio Gasparini
SPS. Pelo
S. Pelo
PDP. Doneddu
P. Doneddu
MTmattia todaro
mattia todaro
AMAlessandro Moro
Alessandro Moro