This study aimed to investigate the effects of oral administration of Platonia insignis Mart. (“bacuri”) seed butter (BSB) on oxidative stress and diabetes mellitus-related parameters in streptozotocin-induced (STZ) diabetic rats. Diabetes mellitus was induced in female Wistar rats (180–250 g) by the intraperitoneal administration of STZ (45 mg/kg, b.w). BSB (25, 50, and 100 mg/kg) was administered to animals for four weeks. The effect on weight gain, food intake, blood glucose, glycated hemoglobin, hepatic transaminases, plasma and liver TBARS and MPO activity, erythrocyte SOD activity, non-protein sulfhydryl groups (SH-NP), and histopathology of the liver tissue was investigated. BSB at the dose of 100 mg/kg had a positive effect on the reduction in glycated hemoglobin percentage and increased albumin concentration, as well as decreased ALT and AST levels and increased SH-NP liver levels in treated animals compared to normal control rats. Moreover, BSB had no effects on weight gain, food intake, and fasting glucose. Thus, the BSB presented marked properties in improvement of hepatic antioxidant defenses, which demonstrates BSB as a potential hepatoprotective agent in metabolic disorders.

The present report describes a case of conjoined twins of the cephalo-thoraco-omphalopagus deradelphous type in cats. A feline female was transferred to our veterinary hospital as an emergency for dystocic labor. The stillborn was subjected to radiographic evaluation, and a single skull and two complete distinct vertebral columns were found. Anatomopathological examination revealed that the twins presented the head, chest, and umbilicus as the main points of union and were classified as the cephalo-thoraco-omphalopagus type. In addition, the twins had unique and well-developed faces, which allowed them to be classified as deradelphous. This malformation is rare in domestic animals, and to the best of our knowledge, this type has not been reported in felines. Further studies are warranted on this embryonic alteration, primarily because its etiology remains unknown.

Objetivou-se, com o presente relato, descrever um caso de colite hiperplásica associada ao parasitismo por Strongyloides sp. em um gato macho de dois anos de idade, atendido na emergência apresentando tenesmo e prolapso retal. Foi realizada uma laparotomia exploratória em que foi possível observar nódulos transmurais no ceco e cólon, com diâmetro variando entre 2 e 4mm, de distribuição multifocal a coalescente, consistência firme e que, ao corte, continham sangue. Histologicamente, os nódulos eram áreas circulares compostas por projeções da mucosa intestinal para a submucosa, formadas por estruturas tubulares revestidas por uma camada de enterócitos volumosos monomórficos e raras células caliciformes. Larvas rabditoides, filarioides e adultos com morfologias compatíveis com nematoides do gênero Strongyloides foram observados no lume do epitélio hiperplásico, entre os túbulos e no limite dos nódulos, possivelmente constituindo a causa primária dessas alterações no animal.

A zoofilia pode possibilitar a prática de outros crimes mais graves contra o ser humano, pois a violência doméstica, o abuso de crianças, o álcool e os animais estão intimamente ligados. O objetivo deste trabalho foi descrever um caso de zoofilia em um cão, relatar como as medidas legais têm sido adotadas e destacar o papel do médico veterinário como coadjuvante da justiça. Foi atendido no Hospital Veterinário da Universidade Federal do Piauí (HVU/UFPI), na cidade de Teresina, um cão macho, mestiço, 5 anos, apresentando sinais clínicos de dor abdominal. O exame clínico revelou excitação comportamental, hemorragia subconjuntival no olho direito, paralisia dos membros pélvicos, mucosa anal congestionada e edemaciada, laceração da junção mucocutânea anal com falta de sensibilidade e presença de secreção fluida. Após exames, a análise do material reprodutivo exógeno revelou a presença de espermatozoides humanos. O animal foi submetido a fluidoterapia e medicado. 72 horas após o atendimento de emergência, o animal veio a óbito. Diante desse precedente, o HV/UFPI apresentou queixa na Delegacia Especializada de Polícia Ambiental (DEMA) em Teresina, PI, Brasil. Na audiência de instrução e no julgamento do presente caso, o autor do crime e seu advogado aceitaram a proposta de transação penal, que estabelecia um valor penal em benefício de uma associação de proteção aos animais do estado do Piauí, com prazo para confirmação do depósito na conta indicada.

The aim of this study was to describe the pathological findings and causes of jaundice in 44 cats (Felis catus) over a six-year period. The cats were from two Brazilian metropolitan areas: 34.1% were female, 56.8% were male, and 9.1% had no information regarding their sex. Their ages ranged from 6 months to 13 years. Most of the cats examined were of a mixed breed (40/44), whereas the others were Angora (2/44), Oriental Short Hair (1/44) and Persian (1/44). All animals had mild to marked jaundice, and 39 were diagnosed with mild to marked anemia. The classification of icterus types (pre-hepatic, hepatic and post-hepatic) was based on gross and microscopic findings. Of the 44 animals, 10 were classified as pre-hepatic icterus, 33 with hepatic icterus and seven with post-hepatic icterus. In some cats, two types of icterus were found, of which five were classified as pre-hepatic and hepatic icterus, and one case was hepatic and post-hepatic icterus. According to the gross and microscopic findings, the cause of pre-hepatic icterus was idiopathic hemolytic anemia. The most frequent cause of hepatic icterus was hepatic lipidosis (26/44), followed by perihepatitis and hepatitis compatible with feline infectious peritonitis, lymphoma, glycogenic degeneration, cholangiocarcinoma and metastatic myeloid leukemia. In animals with post-hepatic icterus, the causes included cholangitis due to Platynosomum spp. infection, cholangioma of the common hepatic duct, and chronic cholangitis. Understanding the etiopathogenesis of jaundice requires an accurate clinic-pathological study and concomitant causes of the disease in cats should be considered.