Marco Piccirelli

Dr. Marco Piccirelli


Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 September 2001 in Applied Physics Letters
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Journal Article
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JKJessica Krüger
Jessica Krüger
RPRobert Plass
Robert Plass
LCLe Cevey
Le Cevey
MPMarco Piccirelli
Marco Piccirelli
MGMichael Grätzel
Michael Grätzel
UBUdo Bach
Udo Bach
The performance of solid-state dye-sensitized solar cells based on spiro-MeOTAD was considerably improved by controlling charge recombination across the interface of the heterojunction. This was achieved by blending the hole conductor matrix with a combination of 4-tert-butylpyridine (tBP) and Li[CF3SO2]2N. Open circuit voltages Uoc over 900 mV and short circuit currents Isc up to 5.1 mA were obtained, yielding an overall efficiency of 2.56% at AM1.5 illumination. These values have been fully confirmed at the National Renewable Energy Laboratories for a device with an active area of 1.07 cm2, signifying a dramatic improvement compared to previously reported values for a similar device.

1 October 2013 in Neuron
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Journal Article
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SISandra Iglesias
Sandra Iglesias
CMChristoph Mathys
Christoph Mathys
KBKay H. Brodersen
Kay H. Brodersen
LKLars Kasper
Lars Kasper
MPMarco Piccirelli
Marco Piccirelli
KSKlaas E. Stephan
Klaas E. Stephan

1 November 2016 in European Journal of Radiology
Verified
Journal Article
Closed access
ABAndreas Boss
Andreas Boss
BBBorna Barth
Borna Barth
LFLukas Filli
Lukas Filli
DKDavid Kenkel
David Kenkel
MWMoritz C. Wurnig
Moritz C. Wurnig
CRCaecilia S. Reiner
Caecilia S. Reiner

1 March 2017 in Investigative Radiology
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Journal Article
Closed access
DKDavid Kenkel
David Kenkel
BBBorna K. Barth
Borna K. Barth
MPMarco Piccirelli
Marco Piccirelli
LFLukas Filli
Lukas Filli
TFTim Finkenstaedt
Tim Finkenstaedt
ABAndreas Boss
Andreas Boss
Objectives: The aims of this study were to implement a protocol for simultaneous multislice (SMS) accelerated diffusion-weighted imaging (DWI) of the kidneys and to perform a systematic analysis of image quality of the data sets. Materials and Methods: Ten healthy subjects and 5 patients with renal masses underwent DWI of the kidney in this prospective institutional review board–approved study on a 3 T magnetic resonance scanner. Simultaneous multislice DWI echo-planar sequences (acceleration factors [AFs] 2 and 3) were compared with conventional echo-planar DWI as reference standard for each acquisition scheme. The following 3 acquisition schemes were applied: comparison A, with increased number of acquisitions at constant scan time; comparison B, with reduction of acquisition time; and comparison C, with increased slice resolution (constant acquisition time, increasing number of slices). Interreader reliability was analyzed by calculating the intraclass correlation coefficient (ICC). Qualitative image quality features were evaluated by 2 independent radiologists on a 5-point Likert scale. Quantification accuracy of the apparent diffusion coefficients (ADCs) and signal-to-noise ratios (SNRs) were assessed by region of interest analysis. Furthermore, lesion conspicuity in the 5 patients was assessed using a 5-point Likert scale by 2 independent radiologists. Results: Interreader agreement was substantial with an ICC of 0.68 for the overall image quality and an ICC of 0.73 for the analysis of artifacts. In comparison A, AF2 resulted in increased SNR (P < 0.05) by 21% at stable image quality scores (image quality: P = 0.76, artifacts: P = 0.21). In comparison B, applying AF2, the scan time could be reduced by 46% without significant reduction in qualitative image quality scores (P = 0.059) or SNR (P = 0.126). In comparison C, slice resolution could be improved by 28% using AF2 with stable image quality scores and SNR. In general, AF3 resulted in reduced image quality and SNR. Significantly reduced ADC values were observed for AF3 in comparison C (cortex: P = 0.003; medulla: P = 0.001) compared with the standard echo-planar imaging sequence. The conventional DWI and the SMS DWI with AF2 showed stable lesion conspicuity ([AF1/AF2]: reader 1 [1.8/1.4] and reader 2 [1.8/1.4]). The lesion conspicuity was lower using AF3 (reader 1: 2.2 and reader 2: 1.8). Conclusions: In conclusion, SMS DWI of the kidney is a potential tool to substantially reduce scan time without negative effects on SNR, ADC quantification accuracy, and image quality if an AF2 is used. Although AF3 results in even higher scan time reduction, a negative impact on image quality, SNR, ADC quantification accuracy, and lesion conspicuity must be considered.

1 July 2015 in Investigative Radiology
Verified
Journal Article
Closed access
LFLukas Filli
Lukas Filli
MPMarco Piccirelli
Marco Piccirelli
DKDavid Kenkel
David Kenkel
RGRoman Guggenberger
Roman Guggenberger
GAGustav Md Andreisek
Gustav Md Andreisek
ABAndreas Boss
Andreas Boss
Objective The aim of this study was to investigate the feasibility of accelerated diffusion tensor imaging (DTI) of skeletal muscle using echo planar imaging (EPI) applying simultaneous multislice excitation with a blipped controlled aliasing in parallel imaging results in higher acceleration unaliasing technique. Materials and Methods After federal ethics board approval, the lower leg muscles of 8 healthy volunteers (mean [SD] age, 29.4 [2.9] years) were examined in a clinical 3-T magnetic resonance scanner using a 15-channel knee coil. The EPI was performed at a b value of 500 s/mm2 without slice acceleration (conventional DTI) as well as with 2-fold and 3-fold acceleration. Fractional anisotropy (FA) and mean diffusivity (MD) were measured in all 3 acquisitions. Fiber tracking performance was compared between the acquisitions regarding the number of tracks, average track length, and anatomical precision using multivariate analysis of variance and Mann-Whitney U tests. Results Acquisition time was 7:24 minutes for conventional DTI, 3:53 minutes for 2-fold acceleration, and 2:38 minutes for 3-fold acceleration. Overall FA and MD values ranged from 0.220 to 0.378 and 1.595 to 1.829 mm2/s, respectively. Two-fold acceleration yielded similar FA and MD values (P ≥ 0.901) and similar fiber tracking performance compared with conventional DTI. Three-fold acceleration resulted in comparable MD (P = 0.199) but higher FA values (P = 0.006) and significantly impaired fiber tracking in the soleus and tibialis anterior muscles (number of tracks, P < 0.001; anatomical precision, P ≤ 0.005). Conclusions Simultaneous multislice EPI with blipped controlled aliasing in parallel imaging results in higher acceleration can remarkably reduce acquisition time in DTI of skeletal muscle with similar image quality and quantification accuracy of diffusion parameters. This may increase the clinical applicability of muscle anisotropy measurements.

24 November 2016 in Scientific Reports
Verified
Journal Article
Open access
DPDavid Perruchoud
David Perruchoud
LMLars Michels
Lars Michels
MPMarco Piccirelli
Marco Piccirelli
RGRoger Gassert
Roger Gassert
Silvio IontaSilvio Ionta
Silvio Ionta
Sensorimotor processing specifically impacts mental body representations. In particular, deteriorated somatosensory input (as after complete spinal cord injury) increases the relative weight of visual aspects of body parts’ representations, leading to aberrancies in how images of body parts are mentally manipulated (e.g. mental rotation). This suggests that a sensorimotor or visual reference frame, respectively, can be relatively dominant in local (hands) versus global (full-body) bodily representations. On this basis, we hypothesized that the recruitment of a specific reference frame could be reflected in the activation of sensorimotor versus visual brain networks. To this aim, we directly compared the brain activity associated with mental rotation of hands versus full-bodies. Mental rotation of hands recruited more strongly the supplementary motor area, premotor cortex, and secondary somatosensory cortex. Conversely, mental rotation of full-bodies determined stronger activity in temporo-occipital regions, including the functionally-localized extrastriate body area. These results support that (1) sensorimotor and visual frames of reference are used to represent the body, (2) two distinct brain networks encode local or global bodily representations, and (3) the extrastriate body area is a multimodal region involved in body processing both at the perceptual and representational level.