Dr. Evgenia Sitnikova
Institute of Higher Nervous Activity and Neurophysiology, Moscow, Moskva, Russia
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Academic Career Length
30Years (1997-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 January 2006 in Neuroscience & Biobehavioral Reviews
Journal Article
GVG Vanluijtelaar
G VanluijtelaarEvgenia Sitnikova1 June 2009 in Journal of Neuroscience Methods
Journal Article
Evgenia Sitnikova
Alexander E. HramovAKAlexey A. Koronovsky
Alexey A. KoronovskyGLGilles van Luijtelaar
Gilles van Luijtelaar30 September 2012 in Physics-Uspekhi
Journal Article
APAlexey Pavlov
Alexey PavlovAlexander E. HramovAKAlexey A. Koronovsky
Alexey A. KoronovskyEvgenia Sitnikova
Valeri A. MakarovAOAlexey A Ovchinnikov
Alexey A Ovchinnikov
1 January 2014 in Brain Research
Journal Article
Evgenia SitnikovaAlexander E. Hramov
Vadim GrubovAKAlexey A. Koronovsky
Alexey A. Koronovsky5 October 2007 in Epilepsia
Journal Article
Evgenia SitnikovaGLGilles Van Luijtelaar
Gilles Van Luijtelaar
Summary:
Purpose: The waveform of spontaneous spike‐wave discharges (SWD) in the electroencephalogram (EEG) was delineated in the WAG/Rij rat model of absence epilepsy according to the definitions of clinical electroencephalography. We defined four elements in SWD based on the schema of Weir (1965): Spike 1 and 2, Positive Transient (PT), and Wave. The EEG patterns of generalized type I and local type II SWD in cortical and thalamic areas were analyzed.
Methods: EEGs were recorded in freely moving rats epidurally from different cortical regions and with deep electrodes from the specific and reticular thalamic nuclei. Grand average SWD waveforms were computed to assess spatiotemporal patterns of seizures.
Results: SWD I in the frontal cortex comprised of a large Spike 2 + Wave, and in the thalamus PT + Wave. Small transient spikes were associated with SWD I in the anterior‐middle part of the cortex. SWD II were found in the occipital cortex as a sequence of (occasional) Spike 1 + PT + Wave.
Conclusions: The EEG structure of SWD in WAG/Rij rats was comparable with that of epileptic patients, suggesting face validity of the WAG/Rij model. Fast transients spikes are an integrative part of SWD I. Time‐amplitude linkage between cortical and thalamic counterparts of SWD I suggests a complex spatiotemporal organization of SWD I. The thalamus sustained SWD I, but not SWD II.
1 April 2011 in Clinical Neurophysiology
Journal Article
GLGilles van Luijtelaar
Gilles van LuijtelaarAlexander E. HramovEvgenia SitnikovaAKAlexey A. Koronovsky
Alexey A. KoronovskyAbout Me
Dr. Evgenia Sitnikova is a Head Researcher (Principle Investigator) at the Institute of Higher Nervous Activity and Neurophysiology RAS (IHNA RAS), Moscow, Russia. She obtained her Ph.D. in Physiology of Humans and Animals at IHNA RAS in 2001 and also a Ph.D. in Biological Psychology at Radboud Universiteit Nijmegen in 2008. She has been holding a habilitation degree since 2014. Her research keywords include genetic rat models, absence epilepsy, sleep, adrenergic system, whisker system, somatosensory cortex, thalamo-cortical system, behavioral tests and ultrasonic vocalization.