Pavol Alexy

Prof. Pavol Alexy

orcid

Research Focus & Metrics

Academic Career Length

31Years (1996-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2000 in Polymer
Verified
Journal Article
Closed access
PAPavol Alexy
Pavol Alexy
BKB Košı́ková
B Košı́ková
GPG Podstránska
G Podstránska

1 January 2002 in Polymer Degradation and Stability
Verified
Journal Article
Closed access
PAPavol Alexy
Pavol Alexy
DKDarina Káchová
Darina Káchová
MKMiroslav Kršiak
Miroslav Kršiak
DBDušan Bakoš
Dušan Bakoš
BŠBarbora Šimková
Barbora Šimková

1 July 2018 in International Journal of Biological Macromolecules
Verified
Journal Article
Closed access
MSMichaela Sedničková
Michaela Sedničková
SPSilvie Pekařová
Silvie Pekařová
PKPavel Kucharczyk
Pavel Kucharczyk
JBJán Bočkaj
Ján Bočkaj
IJIvica Janigová
Ivica Janigová
Ivan ChodákIvan Chodák
Ivan Chodák

8 June 2023 in Materials
Verified
Journal Article
Open access
PDF file
SASara Vach Agocsova
Sara Vach Agocsova
MCMartina Culenova
Martina Culenova
IBIvana Bírová
Ivana Bírová
LOLeona Omaníková
Leona Omaníková
BMBarbora Moncmanova
Barbora Moncmanova
PAPavol Alexy
Pavol Alexy
This article provides a thorough overview of the available resorbable biomaterials appropriate for producing replacements for damaged tissues. In addition, their various properties and application possibilities are discussed as well. Biomaterials are fundamental components in tissue engineering (TE) of scaffolds and play a critical role. They need to exhibit biocompatibility, bioactivity, biodegradability, and non-toxicity, to ensure their ability to function effectively with an appropriate host response. With ongoing research and advancements in biomaterials for medical implants, the objective of this review is to explore recently developed implantable scaffold materials for various tissues. The categorization of biomaterials in this paper includes fossil-based materials (e.g., PCL, PVA, PU, PEG, and PPF), natural or bio-based materials (e.g., HA, PLA, PHB, PHBV, chitosan, fibrin, collagen, starch, and hydrogels), and hybrid biomaterials (e.g., PCL/PLA, PCL/PEG, PLA/PEG, PLA/PHB PCL/collagen, PCL/chitosan, PCL/starch, and PLA/bioceramics). The application of these biomaterials in both hard and soft TE is considered, with a particular focus on their physicochemical, mechanical, and biological properties. Furthermore, the interactions between scaffolds and the host immune system in the context of scaffold-driven tissue regeneration are discussed. Additionally, the article briefly mentions the concept of in situ TE, which leverages the self-renewal capacities of affected tissues and highlights the crucial role played by biopolymer-based scaffolds in this strategy.

9 October 2019 in Food Additives & Contaminants: Part A
Verified
Journal Article
Open access
PAPavol Alexy
Pavol Alexy
EAElke Anklam
Elke Anklam
TETon Emans
Ton Emans
AFAntonino Furfari
Antonino Furfari
FGFrancois Galgani
Francois Galgani
BKBirgit Sokull Kluettgen
Birgit Sokull Kluettgen
This paper identifies knowledge gaps on the sustainability and impacts of plastics and presents some recommendations from an expert group that met at a special seminar organised by the European Commission at the end of 2018. The benefits of plastics in society are unquestionable, but there is an urgent need to better manage their value chain. The recently adopted European Strategy for Plastics stressed the need to tackle the challenges related to plastics with a focus on plastic litter including microplastics. Microplastics have been detected mainly in the marine environment, but also in freshwater, soil and air. Based on today’s knowledge they may also be present in food products. Although nanoplastics have not yet been detected, it can be assumed that they are also present in the environment. This emerging issue presents challenges to better understand future research needs and the appropriate immediate actions to be taken to support the necessary societal and policy initiatives. It has become increasingly apparent that a broad and systematic approach is required to achieve sustainable actions and solutions along the entire supply chain. It is recognised that there is a pressing need for the monitoring of the environment and food globally. However, despite the number of research projects increasing, there is still a lack of suitable and validated analytical methods for detection and quantification of micro- and nanoplastics. There is also a lack of hazard and fate data which would allow for their risk assessment. Some priorities are identified in this paper to bridge the knowledge gaps for appropriate management of these challenges. At the same time it is acknowledged that there is a great complexity in the challenges that need to be tackled before a really comprehensive environmental assessment of plastics, covering their entire life cycle, will be possible.

30 September 2022 in Polymers
Verified
Journal Article
Open access
PDF file
MFMária Fogašová
Mária Fogašová
SFSilvestr Figalla
Silvestr Figalla
LDLucia Danišová
Lucia Danišová
EMElena Medlenová
Elena Medlenová
SHSlávka Hlaváčiková
Slávka Hlaváčiková
MKMarkéta Kadlečková
Markéta Kadlečková
In order to make bioplastics accessible for a wider spectrum of applications, ready-to-use plastic material formulations should be available with tailored properties. Ideally, these kinds of materials should also be “home-compostable” to simplify their organic recycling. Therefore, materials based on PLA (polylactid acid) and PHB (polyhydroxybutyrate) blends are presented which contain suitable additives, and some of them contain also thermoplastic starch as a filler, which decreases the price of the final compound. They are intended for various applications, as documented by products made out of them. The produced materials are fully biodegradable under industrial composting conditions. Surprisingly, some of the materials, even those which contain more PLA than PHB, are also fully biodegradable under home-composting conditions within a period of about six months. Experiments made under laboratory conditions were supported with data obtained from a kitchen waste pilot composter and from municipal composting plant experiments. Material properties, environmental conditions, and microbiology data were recorded during some of these experiments to document the biodegradation process and changes on the surface and inside the materials on a molecular level.