Estimating the burden of tuberculosis disease is relevant for assessing and identifying population health status and progress in policies and programs aimed at epidemic control. The objective of this study was to estimate disability-adjusted life years attributable to Tuberculosis in Colombia 2010–2018. A longitudinal descriptive study was conducted. The variables, sex, age groups and origin were studied. This study included 110,475 cases of morbidity and 8514 cases of mortality. Indicators of years of life lost, years of life with disability and disability-adjusted life years at the subnational level were determined using the methodology of the World Health Organization. With the results of this last indicator, an epidemiological risk stratification was carried out. The DALY rate of the study period was 684 (95% CI 581.2–809.1) per 100,000 inhabitants. According to sex, 68.4% occurred in men; for every DALY in women, 2.21 occur in men. People of productive age (15 to 69 years) account for 56% of DALYs. Amazonas (1857.1 CI 95% 1177.1–2389.6) was the territorial entity with the highest rate. A total of 51.5% of the territorial entities of departmental order of the country are of high burden for Tuberculosis. For the first time in Colombia, a comprehensive assessment of the status of the disease burden at a subnational (departmental) territorial level attributable to Tuberculosis is being carried out using the updated World Health Organization methodology. The results obtained allow us to specify that there is a knowledge gap in terms of the realization and clear understanding of the burden of the disease in Colombia. There are territorial gaps that are necessary to know in order to plan, develop, implement and redirect policies to improve health and eliminate disparities according to the territorial context.

Pediatric tuberculosis is a serious infectious disease and a hidden global epidemic. The objective of this study was to describe the epidemiological situation of tuberculosis mortality in children under 15 years of age in Colombia in the period 2010–2018. A longitudinal descriptive study was conducted. The variables sex, age groups, and origin were studied. This study had 260 cases for analysis and was carried out in three phases. The first phase was the determination of the sociodemographic and clinical characteristics. The second phase was the construction of indicators by territorial entities. The third phase was stratification into four epidemiological situations according to the mortality rate and years of life lost. The median age was 7 years (range 0–14), 66.5% of cases were pulmonary tuberculosis (97.7% without bacteriological confirmation), 14.3781 years of life lost were recorded (95% CI: 142.811–168.333), and in children under 10–14 years, the loss was 110,057. Amazonas had the highest adjusted YLL rate (3979.7). In total, 36.4% of the territories had a high mortality, and 30.3% adjusted to the situation designated as 1. This is the first study that has used composite indicators to address the problem of premature mortality from childhood tuberculosis in Colombia. Our results allow us to specify that this disease remains a challenge for public health. It requires models of care and differential strategies by region. It also requires ensuring opportunities in diagnosis with sensitive methods, as well as intersectoral work for the optimal approach.

Introducción. Una tercera parte del incremento de los casos de tuberculosis se atribuye a la propagación del HIV.Objetivo. Describir la infección concomitante de tuberculosis y HIV en el departamento del Meta durante el periodo de 2010 a 2015.Materiales y métodos. Se hizo un estudio observacional, descriptivo y retrospectivo. Se seleccionaron los 219 casos de análisis y se elaboraron dos nuevas bases de datos que fueron analizadas en tres fases: determinación de las características sociodemográficas y clínicas, construcción de indicadores por municipio (prevalencia y éxito terapéutico) y estratificación en situaciones epidemiológicas según la prevalencia (carga) de la enfermedad.Resultados. El 60 % de los municipios se ajustó a la situación designada como 2. El tratamiento de las personas con infección concomitante de tuberculosis y HIV cuya condición de ingreso era nueva, tuvo 2,39 veces más probabilidades de ser exitoso que el de los previamente tratados, siendo esta asociación estadísticamente significativa (razón de posibilidades, RP=2,39; IC95% 1,3-9,6; p=0,01). Conclusión. La estratificación por situaciones epidemiológicas es útil para planificar actividades de prevención y control.