Yaling Zhao

Prof. Dr. Yaling Zhao

Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, China
orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 December 2017 in BMC Public Health
Verified
Journal Article
Open access
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YZYaling Zhao
Yaling Zhao
Liang WangLiang Wang
Liang Wang
HXHong Xue
Hong Xue
HWHuijun Wang
Huijun Wang
YWYoufa Wang
Youfa Wang
China has seen rapid increase in obesity and hypertension prevalence and fast food consumption over the past decade. We examined status and risk factors for Western- and Chinese fast food consumption and their associations with health outcomes in Chinese children, and examined how maternal factors were associated with child health outcomes. Data of 1626 students aged 7–16 (11.6 ± 2.0) years and their parents in four mega-cities across China (Beijing, Shanghai, Nanjing, and Xi’an) were collected in the 2015 baseline survey of the Childhood Obesity Study in China Mega-cities. Weight, height, waist circumference, and blood pressure were measured. Food intake was assessed using questionnaire. Mixed models were used to examine the associations. Among the children, 11.1% were obese, 19.7% were centrally obese, and 9.0% had hypertension. Obesity prevalence was much higher in boys than in girls (15.2% vs. 6.9% and 27.4% vs. 11.7%, respectively, both P < 0.001). About half (51.9% and 43.6%) of children consumed Western and Chinese fast food, respectively, over the past 3 months. Compared to those with college or above maternal education level, those with elementary school or below maternal education level were 49% more likely to consume Western fast food (odds ratio [OR] and 95% confidence interval [CI]: 1.49 [1.10–2.03]). Chinese fast food consumption rate increased by 12% with each year of increase in child’s age (OR and 95% CI: 1.12 [1.02–1.23]). No significant associations between fast food consumption and health outcomes were detected. Adjusting for Western fast food consumption, children with lower maternal education were 71% and 43% more likely to have obesity and central obesity (ORs and 95% CIs: 1.71 [1.12–2.61] and 1.43 [1.00–2.03], respectively), and maternal body mass index was positively associated with child obesity, central obesity, and hypertension (ORs and 95% CIs: 1.11 [1.06–1.17], 1.12 [1.07–1.17], and 1.09 [1.03–1.15], respectively). Results were similar when Chinese fast food consumption was adjusted for. The prevalence of fast food consumption, obesity and hypertension is high among children in major cities in China. Maternal factors affect child outcomes.

21 January 2023 in Journal of Clinical Medicine
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Journal Article
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SCshiyu chen
shiyu chen
WHWeiwei Hu
Weiwei Hu
YYYuhui Yang
Yuhui Yang
JCJiaxin Cai
Jiaxin Cai
YLYaqi Luo
Yaqi Luo
FCFangyao Chen
Fangyao Chen
Since most patients with heart failure are re-admitted to the hospital, accurately identifying the risk of re-admission of patients with heart failure is important for clinical decision making and management. This study plans to develop an interpretable predictive model based on a Chinese population for predicting six-month re-admission rates in heart failure patients. Research data were obtained from the PhysioNet portal. To ensure robustness, we used three approaches for variable selection. Six different machine learning models were estimated based on selected variables. The ROC curve, prediction accuracy, sensitivity, and specificity were used to evaluate the performance of the established models. In addition, we visualized the optimized model with a nomogram. In all, 2002 patients with heart failure were included in this study. Of these, 773 patients experienced re-admission and a six-month re-admission incidence of 38.61%. Based on evaluation metrics, the logistic regression model performed best in the validation cohort, with an AUC of 0.634 (95%CI: 0.599–0.646) and an accuracy of 0.652. A nomogram was also generated. The established prediction model has good discrimination ability in predicting. Our findings are helpful and could provide useful information for the allocation of healthcare resources and for improving the quality of survival of heart failure patients.

21 February 2022 in ChemistrySelect
Verified
Journal Article
Open access
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SWShouting Wang
Shouting Wang
Yang LiuYang Liu
Yang Liu
XLXupo Liu
Xupo Liu
YCYe Chen
Ye Chen
YZYaling Zhao
Yaling Zhao
Shuyan GaoShuyan Gao
Shuyan Gao
Exploring low‐cost and efficient oxygen reduction reaction (ORR) electrocatalysts is essential for clean energy conversion devices, such as fuel cells. Herein, a series of N, S co‐doped carbon‐based materials were synthesized by the one‐step pyrolysis route, using ZnCl 2 ‐Zn(OH) 2 as templates and solidago biomass as carbon and heteroatom sources. The double‐templated ZnCl 2 ‐Zn(OH) 2 system was employed to prepare the appealing carbon materials with hierarchical macro‐meso‐micro structure and high specific area. The invasive species of solidagos, as the precursors, have advantages of low cost and improved ecological diversification to some extent. The optimized catalyst (NSC‐Z 2 ‐L) contains abundant hierarchical macro‐meso‐micro pores, high specific surface area (∼1581 m 2 g −1 ) and N, S content (∼2.25 at.%). The special structure endows the catalyst with excellent ORR half‐wave potential (E 1/2 ) of 0.85 V, 0.77 V and 0.76 V in the alkaline, acidic and neutral media, respectively, which are compatible with those of commercial Pt/C. The remarkable ORR performances are attributed to the hierarchically porous structure, high specific surface area and the synergistic effect of pyridinic‐N, graphitic‐N and C−S−C species. This work provides a valuable reference for achieving high‐performance ORR catalysts derived from low‐cost biomass materials.

21 April 2022 in Nutrients
Verified
Journal Article
Open access
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MYMiaoJIA Yan
MiaoJIA Yan
YLYezhou Liu
Yezhou Liu
LWLichen Wu
Lichen Wu
Huimeng LiuHuimeng Liu
Huimeng Liu
YWYuotng Wang
Yuotng Wang
BMbaibing mi
baibing mi
Objectives: To investigate the association between dietary purine intake and mortality among Chinese adults. Methods: Based on data from the 2004–2015 China Health and Nutrition Survey (CHNS) and the corresponding edition of China Food Composition, the average purine intake per day (mg/day) from 2004 to 2011 was calculated, and the surveyed population was divided into five groups by quintiles. The outcome event and timepoint of concern were defined as death and time, respectively, as reported by family members, recorded until the 2015 survey. Cox proportional hazards regression was used to estimate the hazard ratios (HRs) with 95% confidence intervals (CIs) for death. The possibly nonlinear relationship between purine intake and mortality was examined with restricted cubic splines. Results: We included 17,755 subjects, and the average purine intake among them was 355.07 ± 145.32 mg/day. Purine intake was inversely associated with mortality (Ptrend < 0.001). Compared with the lowest quintiles of purine intake, the highest quintiles (HR = 0.60; 95% CI: 0.46, 0.77) showed a significant association with lower mortality. The negative association with mortality was mainly found in plant-derived purine (Ptrend = 0.001) and, weakly, in animal-derived purine (Ptrend = 0.052). In addition, a U-shaped relationship between purine intake and mortality was observed in males; however, there was no statistically significant dose–response relationship in females. Conclusion: Considering the low-purine-intake levels of the Chinese population, we observed a U-shaped relationship between purine intake and mortality in males, but purine intake may not relate to mortality in females. Future studies should investigate the causal relationship between purine intake and disease burden in China.

19 July 2024 in Scientific Reports
Verified
Journal Article
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JWJinxiang Wang
Jinxiang Wang
GCGuo-hua Chang
Guo-hua Chang
HLHao Liu
Hao Liu
ZYZhuoxin Yin
Zhuoxin Yin
PLPanliang Liu
Panliang Liu
Tianpeng GaoTianpeng Gao
Tianpeng Gao
China is the biggest emitter of greenhouse gases (GHGs) in the world, and agricultural GHG emission accounts for nearly a fifth of the total emission in China. To understand the carbon absorption and emission characteristics of agricultural production systems in those arid oasis areas, a typical representative city in northwestern China, Zhangye City, was selected for study.The emission factor method was used to analyze and calculate the characteristics of changing carbon emission dynamics in the whole agricultural production system in Zhangye city region (38,592 km2) from 2010 to 2021.The results revealed that carbon emissions during agricultural planting mainly come from fertilizers, which account for the highest proportion (47.9%) of total carbon emissions in agricultural planting. Animal enteric fermentation emissions from local livestock farming are the main contributor (86%) to GHG emissions. The annual average carbon absorption intensity is 4.4 t C-eq ha−1 for crop and 2.6 t C-eq ha−1 for the agricultural production system. The ratio of total carbon emissions from agricultural production to carbon sequestration of crops is 1:1.7. We find that the total carbon sequestration slightly exceeds its total carbon emissions in the study region, with an annual average of 41% for its sustainable development index. Carbon emissions of the agricultural production system in this oasis area are mainly driven by the livestock industry, mostly CH4 emissions from cattle raising.Reducing the local carbon emissions from the livestock industry, typically the cattle raising, will play a crucial role in reducing carbon emissions from this local agricultural production system and maintaining its net positive carbon balance.

17 August 2022 in Nutrients
Verified
Journal Article
Open access
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CWChenlu Wu
Chenlu Wu
BMbaibing mi
baibing mi
LWLuo wanrong
Luo wanrong
CBChen binghua Chen binghua Chen binghua
Chen binghua Chen binghua Chen binghua
JMJiao Ma
Jiao Ma
YZYaling Zhao
Yaling Zhao
Objectives: This study assessed the associations between long-term trajectories of percentage of energy from fat (PEF) and obesity among Chinese adults. Methods: Longitudinal data collected by the China Health and Nutrition Survey from 1991 to 2015 were analyzed. A body mass index ≥28.0 was defined as general obesity. Participants’ baseline PEF levels were categorized as lower than the recommendation of the Chinese Dietary Guideline (30%). Patterns of PEF trajectories were identified by latent class trajectory analysis for overall participants and participants in different baseline PEF groups, respectively. Cox proportional hazards regression models with shared frailty were used to estimate associations between PEF and obesity. Results: Data on 13,025 participants with 72,191 visits were analyzed. Four patterns of PEF trajectory were identified for overall participants and participants in three different baseline PEF groups, respectively. Among overall participants, compared with “Baseline Low then Increase Pattern” (from 12% to 20%), participants with “Baseline Normal-Low then Increase-to-High Pattern” (from 20% to 32%) had a higher hazard of obesity (hazard ratio (HR) and 95% confident interval (CI) at 1.18 (1.01–1.37)). Compared with the “Stable Pattern” group (stable at around 18% and 22%, respectively), participants with “Sudden-Increase Pattern” (from 18% to 30%) in the baseline group whose PEF levels were lower than the recommendation and those with “Sudden-Increase then Decrease Pattern” (rapidly increased from 25% to 40%, and then decreased) in the baseline group who met the recommendation had higher hazards of obesity (HRs and 95% CIs being 1.65 (1.13–2.41) and 1.59 (1.03–2.46), respectively). Conclusions: Adults with a trajectory that involved a sudden increase to a high-level PEF had a higher risk of general obesity. People should avoid increasing PEF suddenly.