Michela Maria Dimuccio

Dr. Michela Maria Dimuccio

University of Bari Aldo Moro, Bari, Puglia, Italy
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 December 2022 in Antibiotics
Verified
Journal Article
Open access
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Rifat ullah khanRifat ullah khan
Rifat ullah khan
Prof. Dr. Shabana NazProf. Dr. Shabana Naz
Prof. Dr. Shabana Naz
DMdavide de marzo
davide de marzo
Michela Maria DimuccioMichela Maria Dimuccio
Michela Maria Dimuccio
GBGiancarlo Bozzo
Giancarlo Bozzo
Marco RagniMarco Ragni
Marco Ragni
Over the past 50 years, there has been a rapid increase in the need for poultry meat on a global scale to meet the rising demand from health, ecology, safety and equity. However, there has been a significant rise in recent years in both public demand and scientific interest for organic poultry farming, particularly when using medicinal herbs due to the rising concern of antibiotic resistance in end users. Ban on the use of antibiotics in the poultry industry has resulted in the demand of herbs as alternatives to antibiotics. Various research efforts have illustrated the nutritional value of Aloe vera in improving growth performance and immune status and acting as an antibacterial and anticoccidial agent in poultry. Aloe vera has been used as a supplement in the form of gel, alcoholic extract, powder, polysaccharide and aqueous extract. Aloe vera contains more than 200 nutrients, bioactive compounds, polysaccharides and saponins. In the current review, we have detailed the effect of Aloe vera as an alternative to antibiotics on growth performance, antimicrobial and antiparasitic activities and blood biochemical alternations in poultry.

9 December 2021 in Agriculture
Verified
Journal Article
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GBGiancarlo Bozzo
Giancarlo Bozzo
Marialaura CorrenteMarialaura Corrente
Marialaura Corrente
GTGiovanni Testa
Giovanni Testa
GCGaia Casalino
Gaia Casalino
Michela Maria DimuccioMichela Maria Dimuccio
Michela Maria Dimuccio
FCFrancesco Emanuele Celentano
Francesco Emanuele Celentano
Climate change is internationally recognized as a source of concern by governments, scientists and public opinion. In this context, the need to find concrete solutions becomes increasingly urgent. Numerous economic sectors contribute to alteration of climate, especially livestock and, more generally, food production-related activities. For this reason, animal welfare policies, the complex of norms and regulations adopted by single Member States and the European Union in the field of meat production, could be a useful instrument in the climate transition invoked by policy makers and scientists. The aim of this paper was to analyze the current system of animal welfare from a legal and veterinary perspective, and to demonstrate how important and useful, it could be in the fight against climate change; at least if correctly implemented and applied.

8 January 2026 in Antibiotics
Verified
Journal Article
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Michela Maria DimuccioMichela Maria Dimuccio
Michela Maria Dimuccio
VCVirginia Conforti
Virginia Conforti
FCFrancesco Emanuele Celentano
Francesco Emanuele Celentano
Elena CircellaElena Circella
Elena Circella
Anna SalvaggiuloAnna Salvaggiulo
Anna Salvaggiulo
Marialaura CorrenteMarialaura Corrente
Marialaura Corrente
Antimicrobial resistance (AMR) represents a significant global concern, undermining the efficacy of treatments in both human and veterinary medicine. Livestock production plays a major role in the emergence and dissemination of AMR, primarily due to the extensive use of antibiotics for therapeutic, prophylactic, and metaphylactic purposes. Addressing this multifaceted issue necessitates a One Health approach. At the international level, regulatory frameworks are predominantly non-binding, relying on soft-law instruments developed by the World Health Organization (WHO), the Food and Agriculture Organization (FAO), and the World Organization for Animal Health (WOAH, formerly OIE), which advocate for harmonized guidelines and national action plans. In contrast, the European Union has implemented binding regulations, including Regulation (EU) 2019/6 and Regulation (EU) 2019/4, which restrict non-essential antimicrobial use (AMU) and reinforce veterinary accountability. Initiatives such as the Farm to Fork Strategy and platforms like ClassyFarm further advance antimicrobial stewardship by integrating animal welfare, sustainability, and access to EU funding. Achieving substantial reductions in AMR within livestock systems requires coordinated, cross-disciplinary, and multi-level governance efforts. The EU model illustrates how enforceable legal frameworks, combined with science-based monitoring and welfare incentives, can facilitate prudent antibiotic use and promote sustainable animal production. This review aims to provide an integrated overview of international and European strategies for regulating antibiotic use in food-producing animals, focusing on how scientific, veterinary and legal perspectives contribute to combating AMR and promoting animal welfare by emphasizing prevention, and a prudent and responsible AMU.

10 November 2024 in Toxins
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Journal Article
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EBElisabetta Bonerba
Elisabetta Bonerba
AMAlessio Manfredi
Alessio Manfredi
Michela Maria DimuccioMichela Maria Dimuccio
Michela Maria Dimuccio
PLPatrizio Lorusso
Patrizio Lorusso
APAnnamaria Pandiscia
Annamaria Pandiscia
GBGiancarlo Bozzo
Giancarlo Bozzo
Ochratoxin A (OTA) is a mycotoxin produced by fungi species belonging to the genera Aspergillus spp. and Penicillium spp. The proliferation of OTA-producing fungal species may occur due to inadequate practices during both the pre-harvest and post-harvest stages of feed. Consequently, poultry species may be exposed to high concentrations of this mycotoxin that can be transferred to animal tissues due to its carry-over, reaching dangerous concentrations in meat and meat products. Therefore, this review aims to propose a comprehensive overview of the effects of OTA on human health, along with data from global studies on the prevalence and concentrations of this mycotoxin in avian feeds, as well as in poultry meat, edible offal, and eggs. Moreover, the review examines significant gross and histopathological lesions in the kidneys and livers of poultry linked to OTA exposure. Finally, the key methods for OTA prevention and decontamination of feed are described.

16 August 2023 in Animals
Verified
Journal Article
Open access
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GCGaia Casalino
Gaia Casalino
FDFrancesca Dinardo
Francesca Dinardo
Francesco D'AmicoFrancesco D'Amico
Francesco D'Amico
GBGiancarlo Bozzo
Giancarlo Bozzo
ABAntonella Bove
Antonella Bove
Elena CircellaElena Circella
Elena Circella
Colibacillosis, caused by E. coli, is responsible for economic losses in the poultry industry due to mortality, decreased production, and the cost of antibiotic treatments. Prevention of colibacillosis is based on improved biosecurity measures and the use of the vaccine performed with O78 E. coli strains, which is responsible for most cases of colibacillosis. Recently, there has been increased interest in other infection control methods, such as the use of natural compounds. The aim of this study was to evaluate the antimicrobial efficacy of cinnamon essential oil (CEO) against E. coli strains isolated from poultry. The MIC50 and MIC90 of CEO were determined by testing 117 strains belonging to serogroups O78, O2, O128, O139, isolated from laying hens (91 strains), broilers (10 strains), and turkeys (16 strains). The bacterial strains were tested at cell densities of 108 and 106 CFU/mL. At the cell density of 108 CFU/mL, MIC50 and MIC90 were 0.4 and 0.5 µL/mL for most of the tested strains, while they corresponded to 0.5 µL/mL for all strains isolated from broilers and for strains belonging to serogroup O139. At the cell density of 106 CFU/mL, MIC50 and MIC90 were 0.3 and 0.4 µL/mL, regardless of bird species of origin and for strains belonging to serogroups O78 and O2. In addition, a concentration of 0.04 µL/mL of CEO corresponded both to MIC50 and MIC90 for strains belonging to serogroups O139 and O128. Based on these results, cinnamon essential oil showed an effective antibacterial activity against E. coli strains from poultry and could find field application for the prevention of colibacillosis.

10 December 2021 in Saudi Journal of Biological Sciences
Verified
Journal Article
Open access
RBRoberta Barrasso
Roberta Barrasso
ECEdmondo Ceci
Edmondo Ceci
Vincenzo TufarelliVincenzo Tufarelli
Vincenzo Tufarelli
GCGaia Casalino
Gaia Casalino
Francesco LuposellaFrancesco Luposella
Francesco Luposella
GBGiancarlo Bozzo
Giancarlo Bozzo
The main objective of this study was to investigate the influence of different types of slaughtering on the variations of pH and temperature. Ninety entire male beef cattle, belonging to the Charolais breed, were distributed in three groups based on method of slaughtering. A total of 30 subjects (group K) were slaughtered without stunning, according to the Koscher rite; thirty bovines (group T) were stunned with a captive bolt gun, following the common slaughtering reported by Council Regulation (EC) 1099/2009; other thirty animals (group H) were slaughtered without stunning, based on Halal procedures. The temperature and pH values of carcasses were determined at 3, 6 and 24 h post-mortem, respectively. At 24 h post-mortem of the 30 carcasses evaluated for each group, muscle temperature decreased in all three types of slaughtering. In particular, the average temperature was 4.0, 4.9 and 3.0 °C for traditional, Halal and Koscher slaughtering, respectively. Moreover, at the same time step (24 h post-mortem), muscle pH decreased showing values equal to 5.72, 5.83, 5.81 for traditional, Halal and Koscher slaughtering, respectively. The findings of the present study may be useful to highlight the influence of slaughtering method on pH and, more generally, on meat quality. Additionally, our results show that, in slaughtering carried out without prior stunning, the carcass could be more susceptible to alterations because of the high pH values.