ALEX A SAEZ

Dr. ALEX A SAEZ

orcid

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 March 2024 in Biology
Verified
Journal Article
Open access
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AMAlejandra M. Miranda
Alejandra M. Miranda
FHFabian Hernandez-Tenorio
Fabian Hernandez-Tenorio
FRFabián Villalta Romero
Fabián Villalta Romero
GVGabriel Jaime Vargas
Gabriel Jaime Vargas
ASALEX A SAEZ
ALEX A SAEZ
Microalgae have commercial potential in different sectors of the industry. Specifically in modern agriculture, they can be used because they have the ability to supply nutrients to the soil and produce plant growth hormones, polysaccharides, antimicrobial compounds, and other metabolites that improve agricultural productivity. Therefore, products formulated from microalgae as biofertilizers and biostimulants turn out to be beneficial for agriculture and are positioned as a novel and environmentally friendly strategy. However, these bioproducts present challenges in preparation that affect their shelf life due to the rapid degradation of bioformulated products. Therefore, this work aimed to provide a comprehensive review of biofertilizers and biostimulants from microalgae, for which a bibliometric analysis was carried out to establish trends using scientometric indicators, technological advances were identified in terms of formulation methods, and the global market for these bioproducts was analyzed.

27 October 2022 in Agronomy
Verified
Journal Article
Open access
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FHFabian Hernandez-Tenorio
Fabian Hernandez-Tenorio
AMAlejandra M. Miranda
Alejandra M. Miranda
CRCarlos A. Rodríguez
Carlos A. Rodríguez
CGCatalina Giraldo-Estrada
Catalina Giraldo-Estrada
ASALEX A SAEZ
ALEX A SAEZ
Biopesticides are pest and pathogen management agents based on living microorganisms or natural products (botanical origin). Due to their natural origins, they stand out as an environmentally friendly tool, since they quickly decompose and minimize pollution problems produced by synthetic pesticides. However, these products present significant challenges that affect the bioactivities of the active components, due to the degradation of the biomass or bioactive metabolite by factors such as air, light, and temperature. Therefore, in this study, a systematic search of the Scopus database was conducted and scientometric tools were used to evaluate formulation techniques and approaches that seek to improve the bioactivities of natural preparations. The results showed that published research on biopesticides has significantly increased by 71.24% in the last decade (2011–2021). Likewise, the bibliometrics showed, through temporal flow analysis, and in the period from 2010 to 2021, investigations evolved have toward the use of nanotechnology, with the purpose of improving and potentiating the formulations of biopesticides. Consequently, nanotechnology tools can be classified as current strategies of interest that allow the increase and protection of bioefficacy to a greater extent than traditional biopesticide preparations. This review constitutes an important contribution to future research and expands the panorama in relation to biopesticide formulations for the control of agricultural pests.

22 July 2022 in Molecules
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Journal Article
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AMAlejandra M. Miranda
Alejandra M. Miranda
FHFabian Hernandez-Tenorio
Fabian Hernandez-Tenorio
DEDAVID OCAMPO ECHEVERRI
DAVID OCAMPO ECHEVERRI
GVGabriel Jaime Vargas
Gabriel Jaime Vargas
ASALEX A SAEZ
ALEX A SAEZ
The alarming levels of carbon dioxide (CO2) are an environmental problem that affects the economic growth of the world. CO2 emissions represent penalties and restrictions due to the high carbon footprint. Therefore, sustainable strategies are required to reduce the negative impact that occurs. Among the potential systems for CO2 capture are microalgae. These are defined as photosynthetic microorganisms that use CO2 and sunlight to obtain oxygen (O2) and generate value-added products such as biofuels, among others. Despite the advantages that microalgae may present, there are still technical–economic challenges that limit industrial-scale commercialization and the use of biomass in the production of added-value compounds. Therefore, this study reviews the current state of research on CO2 capture with microalgae, for which bibliometric analysis was used to establish the trends of the subject in terms of scientometric parameters. Technological advances in the use of microalgal biomass were also identified. Additionally, it was possible to establish the different cooperation networks between countries, which showed interactions in the search to reduce CO2 concentrations through microalgae.

12 May 2023 in Biology
Verified
Journal Article
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BHBrenda S. Hoyos
Brenda S. Hoyos
FHFabian Hernandez-Tenorio
Fabian Hernandez-Tenorio
AMAlejandra M. Miranda
Alejandra M. Miranda
Diego Villanueva-MejíaDiego Villanueva-Mejía
Diego Villanueva-Mejía
ASALEX A SAEZ
ALEX A SAEZ
Se is one of the essential nutrients for human health and animal growth; it participates in various physiological functions, such as antioxidant and immune response and metabolism. Se deficiency is related in the animal industry to poor production performance and the appearance of health problems in humans. Therefore, interest has arisen in producing fortified foods, nutritional supplements, and animal feed products enriched with Se. A sustainable strategy for bio-based products enriched with Se is microalgae. These are characterized by the ability to bioaccumulate inorganic Se and metabolize it into organic Se for product formulations of industrial interest. Although there are some reports on Se bioaccumulation, further exploration is needed to understand the effects of Se bioaccumulation in microalgae. Therefore, this article presents a systematic review of the genes or groups of genes that trigger biological responses associated with the metabolization of Se in microalgae. A total of 54,541 genes related to Se metabolization distributed in 160 different classes were found. Similarly, trends were identified through bibliometric networks on strains of greatest interest, bioproducts, and scientific production.

1 February 2019 in Información tecnológica
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Journal Article
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AMAlejandra M. Miranda
Alejandra M. Miranda
AOAlex Ossa
Alex Ossa
GVGabriel Jaime Vargas
Gabriel Jaime Vargas
ASALEX A SAEZ
ALEX A SAEZ
En este trabajo se evalúa el efecto de la concentración de nitrógeno y fósforo sobre la acumulación de Astaxantina en Haematococcus pluvialis UTEX 2505, utilizando un diseño de experimentos factorial 32. Las variables de respuestas cuantificadas fueron el crecimiento celular, la producción de Astaxantina, perfil lipídico y el módulo de Young de la membrana celular. Se encontró que la productividad celular aumenta al incrementar los niveles de nitrógeno, en contraste con las bajas concentraciones de nitrógeno y fósforo que muestra un efecto positivo sobre la producción de Astaxantina. El estrés generado por la limitación de nutrientes (fuente de nitrógeno y fósforo) disminuye la rigidez de la pared celular en la microalga. Como conclusión, para obtener concentraciones más altas de Astaxantina, es necesario limitar los niveles de nitrógeno y fósforo.

10 October 2022 in Polymers
Verified
Journal Article
Open access
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FHFabian Hernandez-Tenorio
Fabian Hernandez-Tenorio
HMHector Andres Arroyave Miranda
Hector Andres Arroyave Miranda
AMAlejandra M. Miranda
Alejandra M. Miranda
SGSandra Milena Gonzalez
Sandra Milena Gonzalez
CRCarlos A. Rodríguez
Carlos A. Rodríguez
ASALEX A SAEZ
ALEX A SAEZ
Natural Rubber Field Latex (NRFL) allergens restrict its use in some markets due to health-threatening allergic reactions. These molecules are proteins that are related to asymptomatic sensitization and hypersensitivity mediated by immunoglobulin E (IgE). Although NRFL allergens have been investigated since the 1980s, there are still gaps in knowledge regarding the development of deproteinized natural rubber (DPNR). Therefore, in this study, the deproteinization of NRFL from the lower basin of the Cauca River, Antioquia-Colombia was evaluated using eight systems. The highest removal value was 84.4% and was obtained from the treatment containing SDS (Sodium dodecyl sulfate), Urea, and Ethanol. It was also possible to determine that at high concentrations of SDS, removal percentages higher than 70% are reached. On the other hand, all deproteinizing systems decreased NRFL Zeta potentials without self-coagulation, suggesting enhanced colloidal stability in DPNR latex. On the other hand, the bibliometric analysis presented technological advances in DPRN through different parameters and bibliometric networks. The analysis presented makes an important contribution from the bibliometric approach that could be positive for the development of research on DPNR.