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Paula Pinto
Life Quality Research Centre (CIEQV), IPSantarém/IPLeiria, 2040-413 Rio Maior, Portugal

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Journal article
Published: 23 April 2021 in Nutrients
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The Mediterranean diet (MD) has been sponsored worldwide as a healthy and sustainable diet. Our aim was to update and compare MD adherence and food choices across several Southern European countries: Spain (SP), Portugal (PT), Italy (IT), Greece (GR), and Cyprus (CY) (MED, Mediterranean), and Bulgaria (BG) and the Republic of North Macedonia (NMK) (non-MED, non-Mediterranean). Participants (N = 3145, ≥18 y) completed a survey (MeDiWeB) with sociodemographic, anthropometric, and food questions (14-item Mediterranean Diet Adherence Screener, 14-MEDAS). The MED and non-MED populations showed moderate (7.08 ± 1.96) and weak (5.58 ± 1.82) MD adherence, respectively, with significant yet small differences across countries (SP > PT > GR > IT > CY > BG > NMK, p-value < 0.001). The MED participants scored higher than the non-MED ones for most of the Mediterranean-typical foods, with the greatest differences found for olive oil (OO) and white meat preference. In most countries, ≥70% of the participants reported quantities of red meat, butter, sweet drinks, and desserts below the recommended cutoff points, whereas <50% achieved the targets for plant-based foods, OO, fish, and wine. Being a woman and increasing age were associated with superior adherence (p-value < 0.001), but differences were rather small. Our results suggest that the campaigns carried out to support and reinforce the MD and to promote plant-based foods have limited success across Southern Europe, and that more hard-hitting strategies are needed.

ACS Style

Stefano Quarta; Marika Massaro; Mihail Chervenkov; Teodora Ivanova; Dessislava Dimitrova; Rui Jorge; Vanda Andrade; Elena Philippou; Constantinos Zisimou; Viktorija Maksimova; Katarina Smilkov; Darinka Ackova; Lence Miloseva; Tatjana Ruskovska; Georgia Deligiannidou; Christos Kontogiorgis; Julio Sánchez-Meca; Paula Pinto; María-Teresa García-Conesa. Persistent Moderate-to-Weak Mediterranean Diet Adherence and Low Scoring for Plant-Based Foods across Several Southern European Countries: Are We Overlooking the Mediterranean Diet Recommendations? Nutrients 2021, 13, 1432 .

AMA Style

Stefano Quarta, Marika Massaro, Mihail Chervenkov, Teodora Ivanova, Dessislava Dimitrova, Rui Jorge, Vanda Andrade, Elena Philippou, Constantinos Zisimou, Viktorija Maksimova, Katarina Smilkov, Darinka Ackova, Lence Miloseva, Tatjana Ruskovska, Georgia Deligiannidou, Christos Kontogiorgis, Julio Sánchez-Meca, Paula Pinto, María-Teresa García-Conesa. Persistent Moderate-to-Weak Mediterranean Diet Adherence and Low Scoring for Plant-Based Foods across Several Southern European Countries: Are We Overlooking the Mediterranean Diet Recommendations? Nutrients. 2021; 13 (5):1432.

Chicago/Turabian Style

Stefano Quarta; Marika Massaro; Mihail Chervenkov; Teodora Ivanova; Dessislava Dimitrova; Rui Jorge; Vanda Andrade; Elena Philippou; Constantinos Zisimou; Viktorija Maksimova; Katarina Smilkov; Darinka Ackova; Lence Miloseva; Tatjana Ruskovska; Georgia Deligiannidou; Christos Kontogiorgis; Julio Sánchez-Meca; Paula Pinto; María-Teresa García-Conesa. 2021. "Persistent Moderate-to-Weak Mediterranean Diet Adherence and Low Scoring for Plant-Based Foods across Several Southern European Countries: Are We Overlooking the Mediterranean Diet Recommendations?" Nutrients 13, no. 5: 1432.

Journal article
Published: 16 December 2020 in Nutrients
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The Mediterranean diet (MD) and other lifestyle characteristics have been associated with well-being, a broad multiparameter concept that includes individual’s subjective assessment of their own well-being (SWB). Some studies have suggested that diet influences SWB, thus, this work aimed to add novel information on the association of MD and SWB in a sample of Portuguese adults. Data on sociodemographic, economic, lifestyle, diet, and SWB were collected through a self-filled online questionnaire. MD adherence was assessed by the Mediterranean Diet Adherence Screener (MEDAS) score ]. Results showed a moderate adherence to the MD in 490 Portuguese adults (mean MEDAS of 7.4 ± 2.1). A higher MD adherence was found to be significantly positively associated with women, employed individuals, a higher number of meals per day, and those with frequent contact with nature (p-value < 0.0025, using Bonferroni adjustment). As a novelty, this study divided the participants into low SWB, medium SWB, and medium to high SWB profiles (3.9 ± 1.0; 6.2 ± 1.0; 8.2 ± 1.3, respectively; p-value < 0.05), which reported significantly increasing MEDAS scores (6.5 ± 2.1; 7.3 ± 2.1; 7.8 ± 1.9; respectively, p-value < 0.05).

ACS Style

Vanda Andrade; Rui Jorge; María-Teresa García-Conesa; Elena Philippou; Marika Massaro; Mihail Chervenkov; Teodora Ivanova; Viktorija Maksimova; Katarina Smilkov; Darinka Gjorgieva Ackova; Lence Miloseva; Tatjana Ruskovska; Georgia Eirini Deligiannidou; Christos A. Kontogiorgis; Paula Pinto. Mediterranean Diet Adherence and Subjective Well-Being in a Sample of Portuguese Adults. Nutrients 2020, 12, 3837 .

AMA Style

Vanda Andrade, Rui Jorge, María-Teresa García-Conesa, Elena Philippou, Marika Massaro, Mihail Chervenkov, Teodora Ivanova, Viktorija Maksimova, Katarina Smilkov, Darinka Gjorgieva Ackova, Lence Miloseva, Tatjana Ruskovska, Georgia Eirini Deligiannidou, Christos A. Kontogiorgis, Paula Pinto. Mediterranean Diet Adherence and Subjective Well-Being in a Sample of Portuguese Adults. Nutrients. 2020; 12 (12):3837.

Chicago/Turabian Style

Vanda Andrade; Rui Jorge; María-Teresa García-Conesa; Elena Philippou; Marika Massaro; Mihail Chervenkov; Teodora Ivanova; Viktorija Maksimova; Katarina Smilkov; Darinka Gjorgieva Ackova; Lence Miloseva; Tatjana Ruskovska; Georgia Eirini Deligiannidou; Christos A. Kontogiorgis; Paula Pinto. 2020. "Mediterranean Diet Adherence and Subjective Well-Being in a Sample of Portuguese Adults." Nutrients 12, no. 12: 3837.

Journal article
Published: 10 October 2020 in Antioxidants
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Chronic neuroinflammation associated with neurodegenerative disorders has been reported to be prevented by dietary components. Particularly, dietary (poly)phenols have been identified as having anti-inflammatory and neuroprotective actions, and their ingestion is considered a major preventive factor for such disorders. To assess the relation between (poly)phenol classes and their bioactivity, we used five different raspberry genotypes, which were markedly different in their (poly)phenol profiles within a similar matrix. In addition, gastro-intestinal bio-accessible fractions were produced, which simulate the (poly)phenol metabolites that may be absorbed after digestion, and evaluated for anti-inflammatory potential using LPS-stimulated microglia. Interestingly, the fraction from genotype 2J19 enriched in ellagitannins, their degradation products and ellagic acid, attenuated pro-inflammatory markers and mediators CD40, NO, TNF-α, and intracellular superoxide via NF-κB, MAPK and NFAT pathways. Importantly, it also increased the release of the anti-inflammatory cytokine IL-10. These effects contrasted with fractions richer in anthocyanins, suggesting that ellagitannins and its derivatives are major anti-inflammatory (poly)phenols and promising compounds to alleviate neuroinflammation

ACS Style

Gonçalo Garcia; Teresa Faria Pais; Paula Pinto; Gary Dobson; Gordon J. McDougall; Derek Stewart; Cláudia Nunes Santos. Bioaccessible Raspberry Extracts Enriched in Ellagitannins and Ellagic Acid Derivatives Have Anti-Neuroinflammatory Properties. Antioxidants 2020, 9, 970 .

AMA Style

Gonçalo Garcia, Teresa Faria Pais, Paula Pinto, Gary Dobson, Gordon J. McDougall, Derek Stewart, Cláudia Nunes Santos. Bioaccessible Raspberry Extracts Enriched in Ellagitannins and Ellagic Acid Derivatives Have Anti-Neuroinflammatory Properties. Antioxidants. 2020; 9 (10):970.

Chicago/Turabian Style

Gonçalo Garcia; Teresa Faria Pais; Paula Pinto; Gary Dobson; Gordon J. McDougall; Derek Stewart; Cláudia Nunes Santos. 2020. "Bioaccessible Raspberry Extracts Enriched in Ellagitannins and Ellagic Acid Derivatives Have Anti-Neuroinflammatory Properties." Antioxidants 9, no. 10: 970.

Journal article
Published: 27 September 2020 in Nutrients
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This study provides comprehensive validation of the 14-item Mediterranean Diet Adherence Screener (14-MEDAS) in an adult population from Greece (GR), Portugal (PT), Italy (IT), Spain (SP), Cyprus (CY), Republic of North Macedonia (NMK), and Bulgaria (BG). A moderate association between the 14-MEDAS and the reference food diary was estimated for the entire population (Pearson r = 0.573, p-value < 0.001; Intraclass Correlation Coefficient (ICC) = 0.692, p-value < 0.001) with the strongest correlation found in GR, followed by PT, IT, SP, and CY. These results were supported by kappa statistics in GR, PT, IT, and SP with ≥50% of food items exhibiting a fair or better agreement. Bland–Altman analyses showed an overestimation of the 14-MEDAS score in the whole population (0.79 ± 1.81, 95%Confidence Interval (CI) 0.61, 0.96), but this value was variable across countries, with GR, NMK, and BG exhibiting the lowest bias. Taking all analyses together, the validation achieved slightly better results in the Mediterranean countries but a definitive validation ranking order was not evident. Considering growing evidence of the shift from Mediterranean Diet (MD) adherence and of the importance of culture in making food choices it is crucial that we further improve validation protocols with specific applications to compare MD adherence across countries.

ACS Style

María-Teresa García-Conesa; Elena Philippou; Christos Pafilas; Marika Massaro; Stefano Quarta; Vanda Andrade; Rui Jorge; Mihail Chervenkov; Teodora Ivanova; Dessislava Dimitrova; Viktorija Maksimova; Katarina Smilkov; Darinka Gjorgieva Ackova; Lence Miloseva; Tatjana Ruskovska; Georgia Eirini Deligiannidou; Christos A. Kontogiorgis; Paula Pinto. Exploring the Validity of the 14-Item Mediterranean Diet Adherence Screener (MEDAS): A Cross-National Study in Seven European Countries around the Mediterranean Region. Nutrients 2020, 12, 2960 .

AMA Style

María-Teresa García-Conesa, Elena Philippou, Christos Pafilas, Marika Massaro, Stefano Quarta, Vanda Andrade, Rui Jorge, Mihail Chervenkov, Teodora Ivanova, Dessislava Dimitrova, Viktorija Maksimova, Katarina Smilkov, Darinka Gjorgieva Ackova, Lence Miloseva, Tatjana Ruskovska, Georgia Eirini Deligiannidou, Christos A. Kontogiorgis, Paula Pinto. Exploring the Validity of the 14-Item Mediterranean Diet Adherence Screener (MEDAS): A Cross-National Study in Seven European Countries around the Mediterranean Region. Nutrients. 2020; 12 (10):2960.

Chicago/Turabian Style

María-Teresa García-Conesa; Elena Philippou; Christos Pafilas; Marika Massaro; Stefano Quarta; Vanda Andrade; Rui Jorge; Mihail Chervenkov; Teodora Ivanova; Dessislava Dimitrova; Viktorija Maksimova; Katarina Smilkov; Darinka Gjorgieva Ackova; Lence Miloseva; Tatjana Ruskovska; Georgia Eirini Deligiannidou; Christos A. Kontogiorgis; Paula Pinto. 2020. "Exploring the Validity of the 14-Item Mediterranean Diet Adherence Screener (MEDAS): A Cross-National Study in Seven European Countries around the Mediterranean Region." Nutrients 12, no. 10: 2960.

Review
Published: 12 February 2020 in European Journal of Nutrition
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(Poly)phenols have been reported to confer protective effects against type 2 diabetes but the precise association remains elusive. This meta-analysis aimed to assess the effects of (poly)phenol intake on well-established biomarkers in people with type 2 diabetes or at risk of developing diabetes. A systematic search was conducted using the following selection criteria: (1) human randomized controlled trials involving individuals with prediabetes and type 2 diabetes; (2) one or more of the following biomarkers: glucose, glycated haemoglobin (HbA1c), insulin, pro-insulin, homeostatic model assessment of insulin resistance (HOMA-IR), islet amyloid polypeptide (IAPP)/amylin, pro-IAPP/pro-amylin, glucagon, C-peptide; (3) chronic intervention with pure or enriched mixtures of (poly)phenols. From 488 references, 88 were assessed for eligibility; data were extracted from 27 studies and 20 were used for meta-analysis. The groups included in the meta-analysis were: (poly)phenol mixtures, isoflavones, flavanols, anthocyanins and resveratrol. Estimated intervention/control mean differences evidenced that, overall, the consumption of (poly)phenols contributed to reduced fasting glucose levels (− 3.32 mg/dL; 95% CI − 5.86, − 0.77; P = 0.011). Hb1Ac was only slightly reduced (− 0.24%; 95% CI − 0.43, − 0.044; P = 0.016) whereas the levels of insulin and HOMA-IR were not altered. Subgroup comparative analyses indicated a stronger effect on blood glucose in individuals with diabetes (− 5.86 mg/dL, 95% CI − 11.34, − 0.39; P = 0.036) and this effect was even stronger in individuals taking anti-diabetic medication (− 10.17 mg/dL, 95% CI − 16.59, − 3.75; P = 0.002). Our results support that the consumption of (poly)phenols may contribute to lower glucose levels in individuals with type 2 diabetes or at risk of diabetes and that these compounds may also act in combination with anti-diabetic drugs.

ACS Style

Ana F. Raimundo; Filipa Félix; Rita Andrade; María-Teresa García-Conesa; Antonio González-Sarrías; João Gilsa-Lopes; Dulce Do O; Rogério Ribeiro; Ana Rodriguez-Mateos; Cláudia N. Santos; Manuel Schär; Ana Silva; Inês Cruz; Brian Wang; Paula Pinto; Regina Menezes. Combined effect of interventions with pure or enriched mixtures of (poly)phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of randomized controlled human trials. European Journal of Nutrition 2020, 59, 1329 -1343.

AMA Style

Ana F. Raimundo, Filipa Félix, Rita Andrade, María-Teresa García-Conesa, Antonio González-Sarrías, João Gilsa-Lopes, Dulce Do O, Rogério Ribeiro, Ana Rodriguez-Mateos, Cláudia N. Santos, Manuel Schär, Ana Silva, Inês Cruz, Brian Wang, Paula Pinto, Regina Menezes. Combined effect of interventions with pure or enriched mixtures of (poly)phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of randomized controlled human trials. European Journal of Nutrition. 2020; 59 (4):1329-1343.

Chicago/Turabian Style

Ana F. Raimundo; Filipa Félix; Rita Andrade; María-Teresa García-Conesa; Antonio González-Sarrías; João Gilsa-Lopes; Dulce Do O; Rogério Ribeiro; Ana Rodriguez-Mateos; Cláudia N. Santos; Manuel Schär; Ana Silva; Inês Cruz; Brian Wang; Paula Pinto; Regina Menezes. 2020. "Combined effect of interventions with pure or enriched mixtures of (poly)phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of randomized controlled human trials." European Journal of Nutrition 59, no. 4: 1329-1343.

Review
Published: 28 February 2018 in International Journal of Molecular Sciences
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Understanding interindividual variability in response to dietary polyphenols remains essential to elucidate their effects on cardiometabolic disease development. A meta-analysis of 128 randomized clinical trials was conducted to investigate the effects of berries and red grapes/wine as sources of anthocyanins and of nuts and pomegranate as sources of ellagitannins on a range of cardiometabolic risk biomarkers. The potential influence of various demographic and lifestyle factors on the variability in the response to these products were explored. Both anthocyanin- and ellagitannin-containing products reduced total-cholesterol with nuts and berries yielding more significant effects than pomegranate and grapes. Blood pressure was significantly reduced by the two main sources of anthocyanins, berries and red grapes/wine, whereas waist circumference, LDL-cholesterol, triglycerides, and glucose were most significantly lowered by the ellagitannin-products, particularly nuts. Additionally, we found an indication of a small increase in HDL-cholesterol most significant with nuts and, in flow-mediated dilation by nuts and berries. Most of these effects were detected in obese/overweight people but we found limited or non-evidence in normoweight individuals or of the influence of sex or smoking status. The effects of other factors, i.e., habitual diet, health status or country where the study was conducted, were inconsistent and require further investigation.

ACS Style

María-Teresa García-Conesa; Karen Chambers; Emilie Combet; Paula Pinto; Mar Garcia-Aloy; Cristina Andrés-Lacueva; Sonia De Pascual-Teresa; Pedro Mena; Aleksandra Konic Ristic; Wendy J. Hollands; Paul A. Kroon; Ana Rodríguez-Mateos; Geoffrey Istas; Christos A. Kontogiorgis; Dilip K. Rai; Eileen R. Gibney; Christine Morand; Juan Carlos Espín; Antonio González-Sarrías. Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses. International Journal of Molecular Sciences 2018, 19, 694 .

AMA Style

María-Teresa García-Conesa, Karen Chambers, Emilie Combet, Paula Pinto, Mar Garcia-Aloy, Cristina Andrés-Lacueva, Sonia De Pascual-Teresa, Pedro Mena, Aleksandra Konic Ristic, Wendy J. Hollands, Paul A. Kroon, Ana Rodríguez-Mateos, Geoffrey Istas, Christos A. Kontogiorgis, Dilip K. Rai, Eileen R. Gibney, Christine Morand, Juan Carlos Espín, Antonio González-Sarrías. Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses. International Journal of Molecular Sciences. 2018; 19 (3):694.

Chicago/Turabian Style

María-Teresa García-Conesa; Karen Chambers; Emilie Combet; Paula Pinto; Mar Garcia-Aloy; Cristina Andrés-Lacueva; Sonia De Pascual-Teresa; Pedro Mena; Aleksandra Konic Ristic; Wendy J. Hollands; Paul A. Kroon; Ana Rodríguez-Mateos; Geoffrey Istas; Christos A. Kontogiorgis; Dilip K. Rai; Eileen R. Gibney; Christine Morand; Juan Carlos Espín; Antonio González-Sarrías. 2018. "Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses." International Journal of Molecular Sciences 19, no. 3: 694.

Journal article
Published: 13 September 2017 in Scientific Reports
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Age-related complications such as neurodegenerative disorders are increasing and remain cureless. The possibility of altering the progression or the development of these multifactorial diseases through diet is an emerging and attractive approach with increasing experimental support. We examined the potential of known bioavailable phenolic sulfates, arising from colonic metabolism of berries, to influence hallmarks of neurodegenerative processes. In silico predictions and in vitro transport studies across blood-brain barrier (BBB) endothelial cells, at circulating concentrations, provided evidence for differential transport, likely related to chemical structure. Moreover, endothelial metabolism of these phenolic sulfates produced a plethora of novel chemical entities with further potential bioactivies. Pre-conditioning with phenolic sulfates improved cellular responses to oxidative, excitotoxicity and inflammatory injuries and this attenuation of neuroinflammation was achieved via modulation of NF-κB pathway. Our results support the hypothesis that these small molecules, derived from dietary (poly)phenols may cross the BBB, reach brain cells, modulate microglia-mediated inflammation and exert neuroprotective effects, with potential for alleviation of neurodegenerative diseases.

ACS Style

Inês Figueira; G. Garcia; R. C. Pimpão; Ana Terrasso; I. Costa; A. F. Almeida; L. Tavares; Teresa Faria Pais; Paula Pinto; M. Rita Ventura; A. Filipe; G. J. McDougall; D. Stewart; K. S. Kim; I. Palmela; Dora Brites; M. A. Brito; C. Brito; C. N. Santos. Polyphenols journey through blood-brain barrier towards neuronal protection. Scientific Reports 2017, 7, 1 -16.

AMA Style

Inês Figueira, G. Garcia, R. C. Pimpão, Ana Terrasso, I. Costa, A. F. Almeida, L. Tavares, Teresa Faria Pais, Paula Pinto, M. Rita Ventura, A. Filipe, G. J. McDougall, D. Stewart, K. S. Kim, I. Palmela, Dora Brites, M. A. Brito, C. Brito, C. N. Santos. Polyphenols journey through blood-brain barrier towards neuronal protection. Scientific Reports. 2017; 7 (1):1-16.

Chicago/Turabian Style

Inês Figueira; G. Garcia; R. C. Pimpão; Ana Terrasso; I. Costa; A. F. Almeida; L. Tavares; Teresa Faria Pais; Paula Pinto; M. Rita Ventura; A. Filipe; G. J. McDougall; D. Stewart; K. S. Kim; I. Palmela; Dora Brites; M. A. Brito; C. Brito; C. N. Santos. 2017. "Polyphenols journey through blood-brain barrier towards neuronal protection." Scientific Reports 7, no. 1: 1-16.

Review
Published: 13 July 2017 in Nutrients
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Several randomized controlled trials (RCTs) and meta-analyses support the benefits of flavanols on cardiometabolic health, but the factors affecting variability in the responses to these compounds have not been properly assessed. The objectives of this meta-analysis were to systematically collect the RCTs-based-evidence of the effects of flavanol-containing tea, cocoa and apple products on selected biomarkers of cardiometabolic risk and to explore the influence of various factors on the variability in the responses to the consumption of these products. A total of 120 RCTs were selected. Despite a high heterogeneity, the intake of the flavanol-containing products was associated using a random model with changes (reported as standardized difference in means (SDM)) in body mass index (−0.15, p < 0.001), waist circumference (−0.29, p < 0.001), total-cholesterol (−0.21, p < 0.001), LDL-cholesterol (−0.23, p < 0.001), and triacylglycerides (−0.11, p = 0.027), and with an increase of HDL-cholesterol (0.15, p = 0.005). Through subgroup analyses, we showed the influence of baseline-BMI, sex, source/form of administration, medication and country of investigation on some of the outcome measures and suggest that flavanols may be more effective in specific subgroups such as those with a BMI ≥ 25.0 kg/m2, non-medicated individuals or by specifically using tea products. This meta-analysis provides the first robust evidence of the effects induced by the consumption of flavanol-containing tea, cocoa and apple products on weight and lipid biomarkers and shows the influence of various factors that can affect their bioefficacy in humans. Of note, some of these effects are quantitatively comparable to those produced by drugs, life-style changes or other natural products. Further, RCTs in well-characterized populations are required to fully comprehend the factors affecting inter-individual responses to flavanol and thereby improve flavanols efficacy in the prevention of cardiometabolic disorders.

ACS Style

Antonio González-Sarrías; Emilie Combet; Paula Pinto; Pedro Mena; Margherita Dall’Asta; Mar Garcia-Aloy; Ana Rodríguez-Mateos; Eileen R. Gibney; Julie Dumont; Marika Massaro; Julio Sánchez-Meca; Christine Morand; María-Teresa García-Conesa. A Systematic Review and Meta-Analysis of the Effects of Flavanol-Containing Tea, Cocoa and Apple Products on Body Composition and Blood Lipids: Exploring the Factors Responsible for Variability in Their Efficacy. Nutrients 2017, 9, 746 .

AMA Style

Antonio González-Sarrías, Emilie Combet, Paula Pinto, Pedro Mena, Margherita Dall’Asta, Mar Garcia-Aloy, Ana Rodríguez-Mateos, Eileen R. Gibney, Julie Dumont, Marika Massaro, Julio Sánchez-Meca, Christine Morand, María-Teresa García-Conesa. A Systematic Review and Meta-Analysis of the Effects of Flavanol-Containing Tea, Cocoa and Apple Products on Body Composition and Blood Lipids: Exploring the Factors Responsible for Variability in Their Efficacy. Nutrients. 2017; 9 (7):746.

Chicago/Turabian Style

Antonio González-Sarrías; Emilie Combet; Paula Pinto; Pedro Mena; Margherita Dall’Asta; Mar Garcia-Aloy; Ana Rodríguez-Mateos; Eileen R. Gibney; Julie Dumont; Marika Massaro; Julio Sánchez-Meca; Christine Morand; María-Teresa García-Conesa. 2017. "A Systematic Review and Meta-Analysis of the Effects of Flavanol-Containing Tea, Cocoa and Apple Products on Body Composition and Blood Lipids: Exploring the Factors Responsible for Variability in Their Efficacy." Nutrients 9, no. 7: 746.

Review
Published: 01 May 2017 in Critical Reviews in Food Science and Nutrition
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Inflammation is a major biological process regulating the interaction between organisms and the environment, including the diet. Because of the increase in chronic inflammatory diseases, and in light of the immune-regulatory properties of breastfeeding, the ability of dairy products to modulate inflammatory processes in humans is an important but unresolved issue. Here, we report a systematic review of 52 clinical trials investigating inflammatory markers in relation to the consumption of dairy products. An inflammatory score (IS) was defined to quantitatively evaluate this interaction. The IS was significantly positive for the entire data set, indicating an anti-inflammatory activity in humans. When the subjects were stratified according to their health status, the IS was strongly indicative of an anti-inflammatory activity in subjects with metabolic disorders and of a pro-inflammatory activity in subjects allergic to bovine milk. Stratifying the data by product categories associated both low-fat and high-fat products, as well as fermented products, with an anti-inflammatory activity. Remarkably, the literature is characterized by a large gap in knowledge on bioavailability of bioactive nutrients. Future research should thus better combine food and nutritional sciences to adequately follow the fate of these nutrients along the gastrointestinal and metabolic axes.

ACS Style

Alessandra Bordoni; Francesca Danesi; Dominique Dardevet; Didier Dupont; Aida S. Fernandez; Doreen Gille; Claudia Nunes dos Santos; Paula Pinto; Roberta Re; Didier Rémond; Danit Shahar; Guy Vergères. Dairy products and inflammation: A review of the clinical evidence. Critical Reviews in Food Science and Nutrition 2017, 57, 2497 -2525.

AMA Style

Alessandra Bordoni, Francesca Danesi, Dominique Dardevet, Didier Dupont, Aida S. Fernandez, Doreen Gille, Claudia Nunes dos Santos, Paula Pinto, Roberta Re, Didier Rémond, Danit Shahar, Guy Vergères. Dairy products and inflammation: A review of the clinical evidence. Critical Reviews in Food Science and Nutrition. 2017; 57 (12):2497-2525.

Chicago/Turabian Style

Alessandra Bordoni; Francesca Danesi; Dominique Dardevet; Didier Dupont; Aida S. Fernandez; Doreen Gille; Claudia Nunes dos Santos; Paula Pinto; Roberta Re; Didier Rémond; Danit Shahar; Guy Vergères. 2017. "Dairy products and inflammation: A review of the clinical evidence." Critical Reviews in Food Science and Nutrition 57, no. 12: 2497-2525.

Review
Published: 09 February 2017 in Nutrients
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Several epidemiological studies have linked flavonols with decreased risk of cardiovascular disease (CVD). However, some heterogeneity in the individual physiological responses to the consumption of these compounds has been identified. This meta‐analysis aimed to study the effect of flavonol supplementation on biomarkers of CVD risk such as, blood lipids, blood pressure and plasma glucose, as well as factors affecting their inter‐individual variability. Data from 18 human randomized controlled trials were pooled and the effect was estimated using fixed or random effects meta‐analysis model and reported as difference in means (DM). Variability in the response of blood lipids to supplementation with flavonols was assessed by stratifying various population subgroups: age, sex, country, and health status. Results showed significant reductions in total cholesterol (DM = −0.10 mmol/L; 95% CI: −0.20, −0.01), LDL cholesterol (DM = −0.14 mmol/L; Nutrients 2017, 9, 117 2 of 21 95% CI: −0.21, 0.07), and triacylglycerol (DM = −0.10 mmol/L; 95% CI: −0.18, 0.03), and a significant increase in HDL cholesterol (DM = 0.05 mmol/L; 95% CI: 0.02, 0.07). A significant reduction was also observed in fasting plasma glucose (DM = −0.18 mmol/L; 95%CI: −0.29, −0.08), and in blood pressure (SBP: DM = −4.84 mmHg; 95% CI: −5.64, −4.04; DBP: DM = −3.32 mmHg; 95% CI: -4.09, -2.55). Subgroup analysis showed a more pronounced effect of flavonol intake in participants from Asian countries and in participants with diagnosed disease or dyslipidemia, compared to healthy and normal baseline values. In conclusion, flavonol consumption improved biomarkers of CVD risk, however, country of origin and health status may influence the effect of flavonol intake on blood lipid levels

ACS Style

Regina Menezes; Ana Rodriguez‐Mateos; Antonia Kaltsatou; Antonio González‐Sarrías; Arno Greyling; Christoforos Giannaki; Cristina Andres‐Lacueva; Dragan Milenkovic; Eileen R. Gibney; Eileen R Gibney Julie Dumont; Manuel Schär; Mar Garcia‐Aloy; Susana Alejandra Palma‐Duran; Tatjana Ruskovska; Viktorija Maksimova; Emilie Combet; Paula Pinto. Impact of Flavonols on Cardiometabolic Biomarkers: A Meta‐Analysis of Randomized Controlled Human Trials to Explore the Role of Inter‐Individual Variability. Nutrients 2017, 9, 117 .

AMA Style

Regina Menezes, Ana Rodriguez‐Mateos, Antonia Kaltsatou, Antonio González‐Sarrías, Arno Greyling, Christoforos Giannaki, Cristina Andres‐Lacueva, Dragan Milenkovic, Eileen R. Gibney, Eileen R Gibney Julie Dumont, Manuel Schär, Mar Garcia‐Aloy, Susana Alejandra Palma‐Duran, Tatjana Ruskovska, Viktorija Maksimova, Emilie Combet, Paula Pinto. Impact of Flavonols on Cardiometabolic Biomarkers: A Meta‐Analysis of Randomized Controlled Human Trials to Explore the Role of Inter‐Individual Variability. Nutrients. 2017; 9 (2):117.

Chicago/Turabian Style

Regina Menezes; Ana Rodriguez‐Mateos; Antonia Kaltsatou; Antonio González‐Sarrías; Arno Greyling; Christoforos Giannaki; Cristina Andres‐Lacueva; Dragan Milenkovic; Eileen R. Gibney; Eileen R Gibney Julie Dumont; Manuel Schär; Mar Garcia‐Aloy; Susana Alejandra Palma‐Duran; Tatjana Ruskovska; Viktorija Maksimova; Emilie Combet; Paula Pinto. 2017. "Impact of Flavonols on Cardiometabolic Biomarkers: A Meta‐Analysis of Randomized Controlled Human Trials to Explore the Role of Inter‐Individual Variability." Nutrients 9, no. 2: 117.

Review
Published: 19 January 2017 in European Journal of Nutrition
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(Poly)phenols (PPs) are plant secondary metabolites widely distributed in dietary sources, and several evidences show that consumption of PP has a positive impact in human health. However, the correct estimation of food intake and the estimation of PP content of foods are essential to associate PPs intake with health effects. This review aimed to gather information from several studies on PP intake in different countries, compare methods used for both assessment of food intake and PP quantification and highlight existing gaps and future directions. Twenty-four studies of PP intake from thirteen countries were selected for analysis. The selected studies included assessment of all plant food groups contributing to PP intake, total PP content and/or content of major classes (flavonoids or phenolic acids), a large study population and both genders. Most studies presented daily intakes of extractable (poly)phenols. Very few studies have determined intake of non-extractable (poly)phenols, which is a very important fraction of PPs contributing to total PP intake. High heterogeneity was observed among countries regarding the intake of total PP intake and the two main PP classes. This may reflect not only different diet patterns, but also different methods used for collecting food consumption data and estimation of PP content. Thus, criteria of harmonization are suggested regarding assessment of food intake, determination of PP content in foods and validation with biomarkers.

ACS Style

Paula Pinto; Cláudia N. Santos. Worldwide (poly)phenol intake: assessment methods and identified gaps. European Journal of Nutrition 2017, 56, 1393 -1408.

AMA Style

Paula Pinto, Cláudia N. Santos. Worldwide (poly)phenol intake: assessment methods and identified gaps. European Journal of Nutrition. 2017; 56 (4):1393-1408.

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Paula Pinto; Cláudia N. Santos. 2017. "Worldwide (poly)phenol intake: assessment methods and identified gaps." European Journal of Nutrition 56, no. 4: 1393-1408.

Journal article
Published: 28 July 2016 in Food Chemistry
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Neuroinflammation is an integral part of the neurodegeneration process inherent to several aging dysfunctions. Within the central nervous system, microglia are the effective immune cells, responsible for neuroinflammatory responses. In this study, raspberries were subjected to in vitro digestion simulation to obtain the components that result from the gastrointestinal (GI) conditions, which would be bioaccessible and available for blood uptake. Both the original raspberry extract and the gastrointestinal bioaccessible (GIB) fraction protected neuronal and microglia cells against H2O2-induced oxidative stress and lipopolysaccharide (LPS)-induced inflammation, at low concentrations. Furthermore, this neuroprotective capacity was independent of intracellular ROS scavenging mechanisms. We show for the first time that raspberry metabolites present in the GIB fraction significantly inhibited microglial pro-inflammatory activation by LPS, through the inhibition of Iba1 expression, TNF-α release and NO production. Altogether, this study reveals that raspberry polyphenols may present a dietary route to the retardation or amelioration of neurodegenerative-related dysfunctions.

ACS Style

Gonçalo Garcia; Sara Nanni; Inês Figueira; Ines Ivanov; Gordon J. McDougall; Derek Stewart; Ricardo Boavida Ferreira; Paula Pinto; Rui F.M. Silva; Dora Brites; Cláudia N. Santos. Bioaccessible (poly)phenol metabolites from raspberry protect neural cells from oxidative stress and attenuate microglia activation. Food Chemistry 2016, 215, 274 -283.

AMA Style

Gonçalo Garcia, Sara Nanni, Inês Figueira, Ines Ivanov, Gordon J. McDougall, Derek Stewart, Ricardo Boavida Ferreira, Paula Pinto, Rui F.M. Silva, Dora Brites, Cláudia N. Santos. Bioaccessible (poly)phenol metabolites from raspberry protect neural cells from oxidative stress and attenuate microglia activation. Food Chemistry. 2016; 215 ():274-283.

Chicago/Turabian Style

Gonçalo Garcia; Sara Nanni; Inês Figueira; Ines Ivanov; Gordon J. McDougall; Derek Stewart; Ricardo Boavida Ferreira; Paula Pinto; Rui F.M. Silva; Dora Brites; Cláudia N. Santos. 2016. "Bioaccessible (poly)phenol metabolites from raspberry protect neural cells from oxidative stress and attenuate microglia activation." Food Chemistry 215, no. : 274-283.

Journal article
Published: 15 December 2015 in Revista Brasileira de Ciências do Envelhecimento Humano
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O envelhecimento é considerado um processo natural de ir ficando mais velho e um reconhecido factor de risco para o desenvolvimento de doenças crónicas incluindo as doenças neurodegenerativas. A nutrição têm vindo a ser indicada como um factor importante e modificável com impacto na sáude e bem estar dos idosos. Entre os compostos bioativos da dieta destacam-se os polifenóis, que estão presents em grandes quantidades nos pequenos frutos. A procura de um envelhecimento saudável levou a uma investigação extensiva das propriedades benéficas para a saúde dos polifenóis de pequenos frutos por estudos in vitro, baseados em modelos celulares, modelos animais assim como estudos em humanos. Esta revisão discute o estado-da-arte do conhecimento sobre o impacto dos polifenóis de frutas vermelhas na saúde humana, as lacunas e a estratégia do laboratório de investigação Nutrição Molecular e Saúde para suportar a exploração dos polifenóis de pequenos frutos como moduladores de um envelhecimento saudável.

ACS Style

Cláudia Nunes Dos Santos; Inês Sousa Costa; Ricardo Boavida Ferreira; Inês Figueira; Diana Macedo; Regina Menezes; Paula Pinto; Lucélia Tavares. Metabolitos de frutas vermelhas para um envelhecimento saudável do cérebro. Revista Brasileira de Ciências do Envelhecimento Humano 2015, 12, 1 .

AMA Style

Cláudia Nunes Dos Santos, Inês Sousa Costa, Ricardo Boavida Ferreira, Inês Figueira, Diana Macedo, Regina Menezes, Paula Pinto, Lucélia Tavares. Metabolitos de frutas vermelhas para um envelhecimento saudável do cérebro. Revista Brasileira de Ciências do Envelhecimento Humano. 2015; 12 (3):1.

Chicago/Turabian Style

Cláudia Nunes Dos Santos; Inês Sousa Costa; Ricardo Boavida Ferreira; Inês Figueira; Diana Macedo; Regina Menezes; Paula Pinto; Lucélia Tavares. 2015. "Metabolitos de frutas vermelhas para um envelhecimento saudável do cérebro." Revista Brasileira de Ciências do Envelhecimento Humano 12, no. 3: 1.

Review
Published: 27 May 2015 in Oncotarget
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// Didier Rémond 1, 2 , Danit R. Shahar 3 , Doreen Gille 4 , Paula Pinto 5, 6 , Josefa Kachal 7 , Marie-Agnès Peyron 1, 2 , Claudia Nunes Dos Santos 6, 8 , Barbara Walther 4 , Alessandra Bordoni 9 , Didier Dupont 10 , Lidia Tomás-Cobos 11 , Guy Vergères 4 1 UMR 1019, UNH, CRNH Auvergne, INRA, 63000 Clermont-Ferrand, France 2 Clermont Université, Université d’Auvergne, Unité de Nutrition Humaine, BP 10448, 63000 Clermont-Ferrand, France 3 Department of Public Health, The S. Daniel Abraham International Center for Health and Nutrition, Ben-Gurion University of the Negev, 84105 Beer-Sheva, Israel 4 Institute for Food Sciences IFS, Agroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Berne, Switzerland 5 Escola Superior Agrária, Insituto Politécnico de Santarém, 2001-904 Santarem, Portugal 6 Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal 7 Israeli Ministry of Health, 93591 Jerusalem, Israel 8 Instituto de Biologia Experimental e Tecnológica, 2780-157 Oeiras, Portugal 9 Department of Agri-Food Sciences and Technologies, University of Bologna, 47521 Cesena, Italy 10 UMR 1253, Science et Technologie du Lait & de l’Œuf, INRA, 35000 Rennes, France 11 ainia Centro Tecnológico, E46980 Paterna (Valencia), Spain Correspondence to: Guy Vergères, e-mail: [email protected] Keywords: malnutrition, gastrointestinal tract, aging, dietary solutions, gerotarget Received: May 06, 2015 Accepted: May 13, 2015 Published: May 27, 2015 ABSTRACT Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking. This review article aims at filling the gap in knowledge between the functional decline of the aging gastrointestinal tract (GIT) and the consequences of malnutrition on the health status of elderly. Changes in the aging GIT include the mechanical disintegration of food, gastrointestinal motor function, food transit, chemical food digestion, and functionality of the intestinal wall. These alterations progressively decrease the ability of the GIT to provide the aging organism with adequate levels of nutrients, what contributes to the development of malnutrition. Malnutrition, in turn, increases the risks for the development of a range of pathologies associated with most organ systems, in particular the nervous-, muscoskeletal-, cardiovascular-, immune-, and skin systems. In addition to psychological, economics, and societal factors, dietary solutions preventing malnutrition should thus propose dietary guidelines and food products that integrate knowledge on the functionality of the aging GIT and the nutritional status of the elderly. Achieving this goal will request the identification, validation, and correlative analysis of biomarkers of food intake, nutrient bioavailability, and malnutrition. Didier Rémond1,2, Danit R. Shahar3, Doreen Gille4, Paula Pinto5,6, Josefa Kachal7, Marie-Agnès Peyron1,2, Claudia Nunes Dos Santos6,8, Barbara Walther4, Alessandra Bordoni9, Didier Dupont10, Lidia Tomás-Cobos11, Guy Vergères4 1UMR 1019, UNH, CRNH Auvergne, INRA, 63000 Clermont-Ferrand, France 2Clermont Université, Université d’Auvergne, Unité de Nutrition Humaine, BP 10448, 63000 Clermont-Ferrand, France 3Department of Public Health, The S. Daniel Abraham International Center for Health and Nutrition, Ben-Gurion University of the Negev, 84105 Beer-Sheva, Israel 4Institute for Food Sciences IFS, Agroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Berne, Switzerland 5Escola Superior Agrária, Insituto Politécnico de Santarém, 2001-904 Santarem, Portugal 6Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal 7Israeli Ministry of Health, 93591 Jerusalem, Israel 8Instituto de Biologia Experimental e Tecnológica, 2780-157 Oeiras, Portugal 9Department of Agri-Food Sciences and Technologies, University of Bologna, 47521 Cesena, Italy 10UMR 1253, Science et Technologie du Lait & de l’Œuf, INRA, 35000 Rennes, France 11ainia Centro Tecnológico, E46980 Paterna (Valencia), Spain Correspondence to: Guy Vergères, e-mail: [email protected] Keywords: malnutrition, gastrointestinal tract, aging, dietary solutions, gerotarget Received: May 06, 2015 Accepted: May 13, 2015 Published: May 27, 2015 ABSTRACT Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking. This review article aims at filling the gap in knowledge between the functional decline of the aging gastrointestinal tract (GIT) and the consequences of malnutrition on the health status of elderly. Changes in the aging GIT include the mechanical disintegration of food, gastrointestinal motor function, food transit, chemical food digestion, and functionality of the intestinal wall. These alterations progressively decrease the ability of the GIT to provide the aging organism with adequate levels of nutrients, what contributes to the development of malnutrition. Malnutrition, in turn, increases the risks for the development of a range of pathologies associated with most organ systems, in particular the nervous-, muscoskeletal-, cardiovascular-, immune-, and skin systems. In addition to psychological, economics, and societal factors, dietary solutions preventing malnutrition should thus propose dietary guidelines and food products that integrate knowledge on the functionality of the aging GIT and the nutritional status of the elderly. Achieving this goal will request the...

ACS Style

Didier Rémond; Danit Shahar; Doreen Gille; Paula Pinto; Josefa Kachal; Marie-Agnès Peyron; Claudia Nunes dos Santos; Barbara Walther; Alessandra Bordoni; Didier Dupont; Lidia Tomás-Cobos; Guy Vergères. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget 2015, 6, 13858 -13898.

AMA Style

Didier Rémond, Danit Shahar, Doreen Gille, Paula Pinto, Josefa Kachal, Marie-Agnès Peyron, Claudia Nunes dos Santos, Barbara Walther, Alessandra Bordoni, Didier Dupont, Lidia Tomás-Cobos, Guy Vergères. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget. 2015; 6 (16):13858-13898.

Chicago/Turabian Style

Didier Rémond; Danit Shahar; Doreen Gille; Paula Pinto; Josefa Kachal; Marie-Agnès Peyron; Claudia Nunes dos Santos; Barbara Walther; Alessandra Bordoni; Didier Dupont; Lidia Tomás-Cobos; Guy Vergères. 2015. "Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition." Oncotarget 6, no. 16: 13858-13898.

Journal article
Published: 01 February 2015 in Mediterranean Journal of Nutrition and Metabolism
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Paula Pinto. Folate intake in a Portuguese female student population and its relation to body mass index, physical activity level and intake of other nutrients. Mediterranean Journal of Nutrition and Metabolism 2015, 8, 75 -83.

AMA Style

Paula Pinto. Folate intake in a Portuguese female student population and its relation to body mass index, physical activity level and intake of other nutrients. Mediterranean Journal of Nutrition and Metabolism. 2015; 8 (1):75-83.

Chicago/Turabian Style

Paula Pinto. 2015. "Folate intake in a Portuguese female student population and its relation to body mass index, physical activity level and intake of other nutrients." Mediterranean Journal of Nutrition and Metabolism 8, no. 1: 75-83.

Journal article
Published: 19 June 2013 in International Journal of Food Sciences and Nutrition
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Fresh fruits, particularly berries, are rich in polyphenols. These bioactive compounds are important in the prevention of chronic inflammatory diseases. The present study aimed to assess polyphenol intake from fresh fruit in Portugal and the relative contribution of berries to overall intake, using an online semi quantitative food frequency questionnaire. Consumption of processed berry products was also studied. Mean fresh fruit consumption was 365.6 ± 8.2 g/day. Berries accounted for 9% of total fresh fruit intake, from which 80% were due to strawberries. Total polyphenol intake from fresh fruits was 783.9 ± 31.7 mg of Gallic Acid Equivalents (GAE) per day, from which 14% were from berries. Within berries, strawberries accounted for 11% of total polyphenol intake, with the other consumed berries accounting for 3% of the total polyphenol intake per day. Main reasons reported for relative low consumption of berries were market availability and price. The most consumed processed berry product was yogurt.

ACS Style

Paula Pinto; Susana Cardoso; Rui Carlos Pimpão; Lucélia Tavares; Ricardo Boavida Ferreira; Cláudia Nunes Santos. Daily polyphenol intake from fresh fruits in Portugal: contribution from berry fruits. International Journal of Food Sciences and Nutrition 2013, 64, 1022 -1029.

AMA Style

Paula Pinto, Susana Cardoso, Rui Carlos Pimpão, Lucélia Tavares, Ricardo Boavida Ferreira, Cláudia Nunes Santos. Daily polyphenol intake from fresh fruits in Portugal: contribution from berry fruits. International Journal of Food Sciences and Nutrition. 2013; 64 (8):1022-1029.

Chicago/Turabian Style

Paula Pinto; Susana Cardoso; Rui Carlos Pimpão; Lucélia Tavares; Ricardo Boavida Ferreira; Cláudia Nunes Santos. 2013. "Daily polyphenol intake from fresh fruits in Portugal: contribution from berry fruits." International Journal of Food Sciences and Nutrition 64, no. 8: 1022-1029.

Journal article
Published: 01 January 2013 in Journal of Berry Research
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BACKGROUND: Blackberries consumption has been associated with health benefits. However, these fruits present a short shelf-life. Thus, food irradiation is a potential alternative technology for conservation of these fruits without use of chemicals. OBJECTIVE: Analyse the potentiality of gamma radiation as a decontamination method for blackberry fruits. METHODS: Fresh packed blackberries were irradiated in a Co-60 source at two doses (1.0 and 1.5 kGy). Bioburden, physical and rheological, sensorial and total soluble content parameters were assessed before irradiation, immediately after and at two days storage time at 4°C. RESULTS: The characterization of blackberries microbiota point out to an average bioburden value of 104 CFU/g and to a microbial population predominantly composed by filamentous fungi. The inactivation studies on the blackberries mesophilic population indicated a limited microbial inactivation (<1 log decimal reduction) for the applied radiation doses, being the surviving population mainly constituted by filamentous fungi and yeast. No effect of irradiation on colour of blackberries was observed. Concerning texture parameters, no significant differences were observed in both fracturability and firmness between non-irradiated and irradiated blackberries immediately after irradiation. In blackberries stored for two days, both parameters were slightly lower in irradiated blackberries, compared to non-irradiated blackberries. The performed sensorial analysis indicated a similar acceptability among irradiated and non-irradiated fruits. CONCLUSION: This work reveals gamma irradiation treatment potential since no major impact was detected on blackberries physical, rheological and sensory attributes. Further studies with longer periods of storage are needed to elucidate the advantages of irradiation as a conservation treatment.© 2013 - IOS Press and the authors. All rights reserved

ACS Style

M. Oliveira; J. Pereira; S. Cabo Verde; M.G. Lima; P. Pinto; P.B. de Oliveira; C. Junqueira; H. Marcos; T. Silva; R. Melo; C.N. Santos; M.L. Botelho. Evaluation of potential of gamma radiation as a conservation treatment for blackberry fruits. Journal of Berry Research 2013, 3, 93 -102.

AMA Style

M. Oliveira, J. Pereira, S. Cabo Verde, M.G. Lima, P. Pinto, P.B. de Oliveira, C. Junqueira, H. Marcos, T. Silva, R. Melo, C.N. Santos, M.L. Botelho. Evaluation of potential of gamma radiation as a conservation treatment for blackberry fruits. Journal of Berry Research. 2013; 3 (2):93-102.

Chicago/Turabian Style

M. Oliveira; J. Pereira; S. Cabo Verde; M.G. Lima; P. Pinto; P.B. de Oliveira; C. Junqueira; H. Marcos; T. Silva; R. Melo; C.N. Santos; M.L. Botelho. 2013. "Evaluation of potential of gamma radiation as a conservation treatment for blackberry fruits." Journal of Berry Research 3, no. 2: 93-102.

Website
Published: 21 August 2006 in Radionuclide Concentrations in Food and the Environment
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During the past two decades, the Food and Agriculture Organization (FAO), the International Atomic Energy Agency (IAEA), and the World Health Organization (WHO) have become closely involved with the issue of food irradiation, since several aspects of this technology fall within their operating mandates. Among the main activities of the IAEA is the encouragement of peaceful uses of nuclear energy. The FAO, on the other hand, must guarantee a global reduction of post-harvest losses as well as the advancement of food quality, safety, and nutrition. The WHO is predominantly concerned with global public health, namely through the reduction of foodborne diseases. 412Under the tutelage of these three United Nations (UN) agencies, irradiation has become one of the most extensively investigated and controversial technologies in food processing. Expert committees have regularly evaluated studies on the safety and proprieties of irradiated foods and have concluded that the process and the resulting foods are safe. WHO has recently reviewed a previous report, and on the basis of extensive scientific evidence, concluded that food irradiated to any dose appropriate to achieve the intended technological objective is both safe to consume and nutritionally adequate [1]. The experts further conclude that no upper dose limit needs to be imposed.

ACS Style

Paula Pinto; Sandra Cabo Verde; Maria João Trigo; Antonieta Santana; Maria Luísa Botelho. Food Irradiation: Microbiological, Nutritional, and Functional Assessment. Radionuclide Concentrations in Food and the Environment 2006, 411 -438.

AMA Style

Paula Pinto, Sandra Cabo Verde, Maria João Trigo, Antonieta Santana, Maria Luísa Botelho. Food Irradiation: Microbiological, Nutritional, and Functional Assessment. Radionuclide Concentrations in Food and the Environment. 2006; ():411-438.

Chicago/Turabian Style

Paula Pinto; Sandra Cabo Verde; Maria João Trigo; Antonieta Santana; Maria Luísa Botelho. 2006. "Food Irradiation: Microbiological, Nutritional, and Functional Assessment." Radionuclide Concentrations in Food and the Environment , no. : 411-438.

Journal article
Published: 01 June 2005 in Biologia plantarum
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Based on the NH2-terminal sequence of three PR-10 isoforms previously identified in Lupinus albus leaves and a conserved amino-acid region in the PR-10 proteins from leguminosae, a pair of oligonucleotides was designed and used to amplify the corresponding cDNA fragment from a L. albus leaves cDNA library. A fragment of DNA of 200 bp was isolated from the polymerase chain reaction (PCR) mixture and subsequently used to screen the cDNA library. A cDNA coding for a PR-10 protein of 158 amino acid residues was cloned and sequenced. Subsequent studies involving Northern and Western blot analysis have shown that the PR-10 protein isoforms are differentially expressed during the development of the healthy lupin plant. High mRNA and protein contents were detected in roots and hypocotyls of both 7- and 20-d-old plants. In young leaves, the mRNA and protein contents were low and increasead in mature leaves. Tissue printing experiments with root sections suggest that the proteins are extracellular and are mainly associated with the vascular tissues in mature roots.

ACS Style

Paula Pinto; Ana I Ribeiro-Barros; Ana Regalado; Claudina Rodrigues-Pousada; C. P. P. Ricardo. Expression of Lupinus albus PR-10 proteins during root and leaf development. Biologia plantarum 2005, 49, 187 -193.

AMA Style

Paula Pinto, Ana I Ribeiro-Barros, Ana Regalado, Claudina Rodrigues-Pousada, C. P. P. Ricardo. Expression of Lupinus albus PR-10 proteins during root and leaf development. Biologia plantarum. 2005; 49 (2):187-193.

Chicago/Turabian Style

Paula Pinto; Ana I Ribeiro-Barros; Ana Regalado; Claudina Rodrigues-Pousada; C. P. P. Ricardo. 2005. "Expression of Lupinus albus PR-10 proteins during root and leaf development." Biologia plantarum 49, no. 2: 187-193.

Journal article
Published: 01 September 2004 in Radiation Physics and Chemistry
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Alternative technologies must be developed and implemented considering sanitation and preservation of eggs mainly for risk population. Food irradiation is an alternative to free Salmonella spp. and Campylobacter spp. eggs, as a low dose point to a safety assurance. This study presents the correlation between irradiation doses (0.5 kGy up to 5 kGy at dose rate of 1.0 kGy/h) and some of functional and nutritional egg properties. Viscosimetry of non-irradiated and irradiated eggs was evaluated by means of VT550 Haake with an NV sensor and co-axes cylinders. After irradiation at 5 kGy, the yolk colour die (pale yellow) and the white egg was modified to a turbid yellow. The Cross equation was utilized to viscosimetry curves. Based on the assymptotics viscosimetry data indicated that increase of doses corresponds to an increase of the yolk and a decrease of white egg viscosimetry as such a Newton behaviour. Irradiation effects on nutritional properties were evaluated by means of egg protein patterns that were assessed by polyacrylamide gel electrophoresis. Lipids were identified by TLC. Based on results the sanitation dose is lower than the limit dose for the decrease of the main eggs properties

ACS Style

P Pinto; R Ribeiro; L Sousa; S.Cabo Verde; M.G Lima; M Dinis; A Santana; M.L Botelho. Sanitation of chicken eggs by ionizing radiation: functional and nutritional assessment. Radiation Physics and Chemistry 2004, 71, 35 -38.

AMA Style

P Pinto, R Ribeiro, L Sousa, S.Cabo Verde, M.G Lima, M Dinis, A Santana, M.L Botelho. Sanitation of chicken eggs by ionizing radiation: functional and nutritional assessment. Radiation Physics and Chemistry. 2004; 71 (1-2):35-38.

Chicago/Turabian Style

P Pinto; R Ribeiro; L Sousa; S.Cabo Verde; M.G Lima; M Dinis; A Santana; M.L Botelho. 2004. "Sanitation of chicken eggs by ionizing radiation: functional and nutritional assessment." Radiation Physics and Chemistry 71, no. 1-2: 35-38.