The human gastrointestinal (GI) tract is an important part of the body. According to World Health Organization (WHO) research, GI tract infections kill 1.8 million people each year. In the year 2019, almost 5 million individuals were detected with gastrointestinal disease. Radiation therapy has the potential to improve cure rates in GI cancer patients. Radiation oncologists direct X-ray beams at the tumour while avoiding the stomach and intestines. The current objective is to direct the X-ray beam toward the malignancy while avoiding the stomach and intestines in order to improve dose delivery to the tumour. This study offered a technique for segmenting GI tract organs (small bowel, big intestine, and stomach) to assist radio oncologists to treat cancer patients more quickly and accurately. The suggested model is a U-Net model designed from scratch and used for the segmentation of a small size of images to extract the local features more efficiently. Furthermore, in the proposed model, six transfer learning models were employed as the backbone of the U-Net topology. The six transfer learning models used are Inception V3, SeResNet50, VGG19, DenseNet121, InceptionResNetV2, and EfficientNet B0. The suggested model was analysed with model loss, dice coefficient, and IoU. The results specify that the suggested model outperforms all transfer learning models, with performance parameter values as 0.122 model loss, 0.8854 dice coefficient, and 0.8819 IoU.

One of the toughest biometrics and document forensics problems is confirming a signature’s authenticity and legal identity. A forgery may vary from a genuine signature by specific distortions. Therefore, it is necessary to continuously monitor crucial distinctions between real and forged signatures for secure work and economic growth, but this is particularly difficult in writer-independent tasks. We thus propose an innovative and sustainable writer-independent approach based on a Siamese neural network for offline signature verification. The Siamese network is a twin-like structure with shared weights and parameters. Similar and dissimilar images are exposed to this network, and the Euclidean distances between them are calculated. The distance is reduced for identical signatures, and the distance is increased for different signatures. Three datasets, namely GPDS, BHsig260 Hindi, and BHsig260 Bengali datasets, were tested in this work. The proposed model was analyzed by comparing the results of different parameters such as optimizers, batch size, and the number of epochs on all three datasets. The proposed Siamese neural network outperforms the GPDS synthetic dataset in the English language, with an accuracy of 92%. It also performs well for the Hindi and Bengali datasets while considering skilled forgeries.

The segmentation of gastrointestinal (GI) organs is crucial in radiation therapy for treating GI cancer. It allows for developing a targeted radiation therapy plan while minimizing radiation exposure to healthy tissue, improving treatment success, and decreasing side effects. Medical diagnostics in GI tract organ segmentation is essential for accurate disease detection, precise differential diagnosis, optimal treatment planning, and efficient disease monitoring. This research presents a hybrid encoder–decoder-based model for segmenting healthy organs in the GI tract in biomedical images of cancer patients, which might help radiation oncologists treat cancer more quickly. Here, EfficientNet B0 is used as a bottom-up encoder architecture for downsampling to capture contextual information by extracting meaningful and discriminative features from input images. The performance of the EfficientNet B0 encoder is compared with that of three encoders: ResNet 50, MobileNet V2, and Timm Gernet. The Feature Pyramid Network (FPN) is a top-down decoder architecture used for upsampling to recover spatial information. The performance of the FPN decoder was compared with that of three decoders: PAN, Linknet, and MAnet. This paper proposes a segmentation model named as the Feature Pyramid Network (FPN), with EfficientNet B0 as the encoder. Furthermore, the proposed hybrid model is analyzed using Adam, Adadelta, SGD, and RMSprop optimizers. Four performance criteria are used to assess the models: the Jaccard and Dice coefficients, model loss, and processing time. The proposed model can achieve Dice coefficient and Jaccard index values of 0.8975 and 0.8832, respectively. The proposed method can assist radiation oncologists in precisely targeting areas hosting cancer cells in the gastrointestinal tract, allowing for more efficient and timely cancer treatment.

Knee osteoarthritis (OA) is a chronic degenerative joint disease affecting millions worldwide, particularly those over 60. It is a significant cause of disability and can impact an individual's quality of life. The condition occurs when the cartilage in the knee joint wears away over time, leading to bone-on-bone contact, which can result in pain, stiffness, swelling, and decreased range of motion. Deep neural networks, especially convolutional neural networks (CNN), are powerful tools in medical applications such as diagnosis and detection. This research proposes a CNN model to classify knee osteoarthritis into five categories using x-ray images. These classes are labeled: Minimal, Healthy, Moderate, Doubtful, and Severe. Furthermore, the proposed CNN model has been compared with two pre-trained transfer learning models: Xception and InceptionResNet V2. These models were evaluated based on precision, recall, F1 score, and accuracy. The results showed that although all three models performed very well, the proposed model outperformed both transfer learning models with 98% accuracy. It also achieved the highest values for other parameters such as precision, recall, and F1 score. The proposed model has several potential applications in clinical practice, such as assisting doctors in accurately classifying knee osteoarthritis severity levels by analyzing single X-ray images.

The gastrointestinal (GI) tract, an integral part of the digestive system, absorbs nutrients from ingested food, starting from the mouth to the anus. GI tract cancer significantly impacts global health, necessitating precise treatment methods. Radiation oncologists use X-ray beams to target tumors while avoiding the stomach and intestines, making the accurate segmentation of these organs crucial. This research explores various combinations of encoders and decoders to segment the small bowel, large bowel, and stomach in MRI images, using the UW-Madison GI tract dataset consisting of 38,496 scans. Encoders tested include ResNet50, EfficientNetB1, MobileNetV2, ResNext50, and Timm_Gernet_S, paired with decoders UNet, FPN, PSPNet, PAN, and DeepLab V3+. The study identifies ResNet50 with DeepLab V3+ as the most effective combination, assessed using the Dice coefficient, Jaccard index, and model loss. The proposed model, a combination of DeepLab V3+ and ResNet 50, obtained a Dice value of 0.9082, an IoU value of 0.8796, and a model loss of 0.117. The findings demonstrate the method’s potential to improve radiation therapy for GI cancer, aiding radiation oncologists in accurately targeting tumors while avoiding healthy organs. The results of this study will assist healthcare professionals involved in biomedical image analysis.