Jorge Manuel Silva Jara

Dr. Jorge Manuel Silva Jara

Farmacobiología, Universidad de Guadalajara, CUCEI, Guadalajara, Jalisco, Mexico
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 May 2024 in Resources
Verified
Journal Article
Open access
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Zuamí VillagránZuamí Villagrán
Zuamí Villagrán
LALuis Anaya
Luis Anaya
CVCarlos Arnulfo Velázquez-Carriles
Carlos Arnulfo Velázquez-Carriles
JJJorge Manuel Silva Jara
Jorge Manuel Silva Jara
JGJOSE RUVALCABA GOMEZ
JOSE RUVALCABA GOMEZ
FMFernando Martínez-Esquivias
Fernando Martínez-Esquivias
The synthesis of inorganic nanoparticles for diverse applications is an active research area that involves physical and chemical methods, which typically are expensive, involve hazardous chemical reagents, use complex equipment and synthesis conditions, and consume large amounts of time and energy. Thus, green synthesis methods have emerged as eco-friendly and easy alternatives for inorganic nanoparticle synthesis, particularly the use of plant-based extracts from fruit juice, leaves, seeds, peel, stem, barks, and roots, which act as reducing, capping, and stabilizing agents, contributing to the Sustainable Development Goals and circular economy principles. Therefore, diverse inorganic nanoparticles have been synthesized using plant-based extracts, including gold, silver, titanium dioxide, zinc, copper, platinum, zirconium, iron, selenium, magnesium, nickel, sulfur, cobalt, palladium, and indium nanoparticles, which exhibit different biological activities such as antioxidant, antimicrobial, dye degradation, cytotoxic, analgesic, sedative, wound-healing, skin protection, sensor development, and plant-growth-promoting effects. Therefore, this review summarizes the advantages and limitations of plant-based extracts as reducing, capping, and stabilizing agents for inorganic nanoparticle green synthesis.

30 April 2025 in Foods
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Journal Article
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YGYaquelin Flores Garcia
Yaquelin Flores Garcia
Martha Fabiola Martin del Campo SolísMartha Fabiola Martin del Campo Solís
Martha Fabiola Martin del Campo Solís
JGJorge H. Gómez-Angulo
Jorge H. Gómez-Angulo
APALMA HORTENSIA MARTINEZ PRECIADO
ALMA HORTENSIA MARTINEZ PRECIADO
JJJorge Manuel Silva Jara
Jorge Manuel Silva Jara
ZGZazil Yadel Escalante García
Zazil Yadel Escalante García
Galactomannans (GMs) are polysaccharides with diverse industrial applications due to their functional properties, such as their use in thickeners, stabilizers, and gelling agents. Their use originated in the food industry and has rapidly expanded to other industries due to their biocompatibility, biodegradability, non-toxicity, and low cost. Galactomannans can be extracted from different plant species, resulting in gums with diverse physicochemical properties. Furthermore, there are different methods for their extraction and purification, each with their own advantages and disadvantages. The structure of galactomannans determines their application in industry, so their characterization is also important. This article presents a comprehensive review of galactomannan sources, as well as their extraction, purification, and characterization methods. It also includes the main applications of these polysaccharides in various sectors.

20 September 2022 in Molecules
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CVCarlos Arnulfo Velázquez-Carriles
Carlos Arnulfo Velázquez-Carriles
María Macías-RodríguezMaría Macías-Rodríguez
María Macías-Rodríguez
OROmar Ramírez-Alvarado
Omar Ramírez-Alvarado
RCRosa Isela Corona-Gonzalez
Rosa Isela Corona-Gonzalez
ALAdriana Macaria Macias Lamas
Adriana Macaria Macias Lamas
JJJorge Manuel Silva Jara
Jorge Manuel Silva Jara
Due to the current concerns against opportunistic pathogens and the challenge of antimicrobial resistance worldwide, alternatives to control pathogen growth are required. In this sense, this work offers a new nanohybrid composed of zinc-layered hydroxide salt (Simonkolleite) and thymol for preventing bacterial growth. Materials were characterized with XRD diffraction, FTIR and UV–Vis spectra, SEM microscopy, and dynamic light scattering. It was confirmed that the Simonkolleite structure was obtained, and thymol was adsorbed on the hydroxide in a web-like manner, with a concentration of 0.863 mg thymol/mg of ZnLHS. Absorption kinetics was described with non-linear models, and a pseudo-second-order equation was the best fit. The antibacterial test was conducted against Escherichia coli O157:H7 and Staphylococcus aureus strains, producing inhibition halos of 21 and 24 mm, respectively, with a 10 mg/mL solution of thymol–ZnLHS. Moreover, biofilm formation of Pseudomonas aeruginosa inhibition was tested, with over 90% inhibition. Nanohybrids exhibited antioxidant activity with ABTS and DPPH evaluations, confirming the presence of the biomolecule in the inorganic matrix. These results can be used to develop a thymol protection vehicle for applications in food, pharmaceutics, odontology, or biomedical industries.

7 July 2023 in Journal of Food Science and Technology
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DRDulce María Romero-García
Dulce María Romero-García
CVCarlos Arnulfo Velázquez-Carriles
Carlos Arnulfo Velázquez-Carriles
CGCesar Gomez
Cesar Gomez
GVGilberto Velázquez-Juárez
Gilberto Velázquez-Juárez
JJJorge Manuel Silva Jara
Jorge Manuel Silva Jara

6 May 2023 in Molecules
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MLMiguel Ángel López-Alvarez
Miguel Ángel López-Alvarez
JJJorge Manuel Silva Jara
Jorge Manuel Silva Jara
JSJazmín Silva
Jazmín Silva
MRMartha Reyes-Becerril
Martha Reyes-Becerril
CVCarlos Arnulfo Velázquez-Carriles
Carlos Arnulfo Velázquez-Carriles
CRCésar Alberto Reynoso-García
César Alberto Reynoso-García
YMnO3 is a P-type semiconductor with a perovskite-type structure (ABO3). It presents two crystalline systems: rhombohedral and hexagonal, the latter being the most stable and studied. In the hexagonal system, Mn3+ ions are coordinated by five oxygen ions forming a trigonal bipyramid, and the Y3+ ions are coordinated by five oxygen ions. This arrangement favors its ferroelectric and ferromagnetic properties, which have been widely studied since 1963. However, applications based on their optical properties have yet to be explored. This work evaluates the photoelectric response and the photocatalytic activity of yttrium manganite in visible spectrum wavelengths. To conduct this, a rod-obelisk-shaped yttrium manganite with a reduced indirect bandgap value of 1.43 eV in its hexagonal phase was synthesized through the precipitation method. The synthesized yttrium manganite was elucidated by solid-state techniques, such as DRX, XPS, and UV-vis. It was non-toxic as shown by the 100% leukocyte viability of mice BALB/c.

3 September 2024 in Sustainability
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Iván Balderas-LeónIván Balderas-León
Iván Balderas-León
JJJorge Manuel Silva Jara
Jorge Manuel Silva Jara
MLMiguel Ángel López-Alvarez
Miguel Ángel López-Alvarez
POPedro Pedro Ortega-Gudiño
Pedro Pedro Ortega-Gudiño
ARArturo Rodríguez
Arturo Rodríguez
CNCristina Neri-Cortés
Cristina Neri-Cortés
The green synthesis of metal oxide nanoparticles (NPs) offers an alternative to chemical procedures, which can be harmful to human health due to exposure to hazardous substances and harsh synthesis conditions. The following work synthesized titanium dioxide nanoparticles (TiO2 NPs) using a green synthesis method. As a precursor, food-grade TiO2 was used with blueberry extract. This approach makes the process safer, cheaper, and simpler, requiring minimal effort to achieve effective TiO2 NP synthesis. The TiO2 NP characterization was performed by solid-state techniques, such as Ultraviolet-visible (UV-Vis) spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and transmission electron microscopy (TEM). According to the XRD diffractograms, TiO2 NPs were obtained in the anatase phase with incidence peaks of 25.28 (101). TEM confirmed their pseudo-spherical shape with an average size of 170 nm. The 3.2 eV bandgap of TiO2 NPs enables UV absorption, making them ideal for efficient photocatalytic degradation under sunlight. On the other hand, the photocatalytic activity of TiO2 NPs was examined using malachite green (MG) dye as a pollutant model under direct sunlight. After 30 min, a degradation of 94% was achieved. The kinetic analysis identified parabolic diffusion and modified-Freundlich kinetics as primary mechanisms, emphasizing diffusion and adsorption in electron transfer. The main reactive oxygen species (ROS) involved in the photodegradation of MG dye were h+ and OH•.