Rajendra Rohokale

Dr. Rajendra Rohokale

Chemistry, University of Florida, Gainesville, Florida, USA
orcid
Research Scientist

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 March 2016 in Synthesis
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Journal Article
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UKUmesh A. Kshirsagar
Umesh A. Kshirsagar
Rajendra RohokaleRajendra Rohokale
Rajendra Rohokale
Quinazolinones are important heterocyclic scaffolds because of their broad spectrum of medicinal and pharmacological properties. The development of advanced synthetic methods to construct the quinazolinone motif is therefore an important aspect of synthetic chemistry. This review emphasises the recent developments in methodologies and advanced synthetic strategies for the quinazolinone core. 1 Introduction 2 Synthesis of 2-Substituted Quinazolinones 2.1 Oxidative Condensation/Cyclization 2.2 Acid-Catalyzed Condensation/Cyclization 2.3 Transition-Metal-Catalyzed C–N Bond Formation 2.4 Transition-Metal-Catalyzed Cyclocarbonylation 3 Synthesis of 3-Substituted Quinazolinones 3.1 Using a Coupling Agent 3.2 Oxidative Condensation/Cyclization 3.3 Transition-Metal-Catalyzed C–N Bond Formation 3.4 Transition-Metal-Catalyzed Cyclocarbonylation 4 Synthesis of 2,3-Disubstituted Quinazolinones 4.1 Dehydrative/Reductive Cyclization 4.2 Oxidative Condensation/Cyclization 4.3 Radical Cyclization 4.4 Transition-Metal-Catalyzed C–N Bond Formation 4.5 Transition-Metal-Catalyzed Cyclocarbonylation 4.6 Acid-Catalyzed Condensation/Cyclization 5 Conclusion


11 July 2016 in The Journal of Organic Chemistry
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Journal Article
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Rajendra RohokaleRajendra Rohokale
Rajendra Rohokale
Burkhard KoenigBurkhard Koenig
Burkhard Koenig
DDDilip D. Dhavale
Dilip D. Dhavale

21 December 2017 in Organic & Biomolecular Chemistry
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Journal Article
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Rajendra RohokaleRajendra Rohokale
Rajendra Rohokale
STShrikant D. Tambe
Shrikant D. Tambe
UKUmesh A. Kshirsagar
Umesh A. Kshirsagar
An eosin Y photoredox catalyzed net redox neutral process for 3-sulfonylindoles via the anionic oxidation of sodium sulfinate salts and its radical cascade cyclization with 2-alkynyl-azidoarenes was developed with visible light as a mediator. The reaction offers metal and oxidant/reductant free, visible light mediated vicinal sulfonamination of alkynes to 2-aryl/alkyl-3-sulfonylindoles and proceeds via the generation of a sulfur-centered radical through direct oxidation of the sulfinate anion by an excited photocatalyst with a reductive quenching cycle. The mild conditions, use of an organic dye as photo-catalyst, bench stability and easily accessible starting materials make the present approach green and attractive.


24 August 2018 in European Journal of Organic Chemistry
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Journal Article
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STShrikant D. Tambe
Shrikant D. Tambe
MJMahesh S. Jadhav
Mahesh S. Jadhav
Rajendra RohokaleRajendra Rohokale
Rajendra Rohokale
UKUmesh A. Kshirsagar
Umesh A. Kshirsagar