Diabetic foot ulcers (DFUs) are the fastest growing chronic complication of diabetes mellitus, with more than 400 million people diagnosed globally, and the condition is responsible for lower extremity amputation in 85% of people affected, leading to high-cost hospital care and increased mortality risk. Neuropathy and peripheral arterial disease trigger deformities or trauma, and aggravating factors such as infection and edema are the etiological factors for the development of DFUs. DFUs require identifying the etiology and assessing the co-morbidities to provide the correct therapeutic approach, essential to reducing lower-extremity amputation risk. This review focuses on the current treatment strategies for DFUs with a special emphasis on tissue engineering techniques and regenerative medicine that collectively target all components of chronic wound pathology.

Agricultural greenhouses must accurately predict environmental factors to ensure optimal crop growth and energy management efficiency. However, the existing predictors have limitations when dealing with dynamic, non-linear, and massive temporal data. This study proposes four supervised learning techniques focused on linear regression (LR) and Support Vector Regression (SVR) to predict the internal temperature of a greenhouse. A meteorological station is installed in the greenhouse to collect internal data (temperature, humidity, and dew point) and external data (temperature, humidity, and solar radiation). The data comprises a one year, and is divided into seasons for better analysis and modeling of the internal temperature. The study involves sixteen experiments corresponding to the four models and the four seasons and evaluating the models’ performance using R${}^2$, RMSE, MAE, and MAPE metrics, considering an acceptability interval of ±2 ${}^{°}$C. The results show that LR models had difficulty maintaining the acceptability interval, while the SVR models adapted to temperature outliers, presenting the highest forecast accuracy among the proposed algorithms.

Breast cancer is one of the diseases of most profound concern, with the most prevalence worldwide, where early detections and diagnoses play the leading role against this disease achieved through imaging techniques such as mammography. Radiologists tend to have a high false positive rate for mammography diagnoses and an accuracy of around 82%. Currently, deep learning (DL) techniques have shown promising results in the early detection of breast cancer by generating computer-aided diagnosis (CAD) systems implementing convolutional neural networks (CNNs). This work focuses on applying, evaluating, and comparing the architectures: AlexNet, GoogLeNet, Resnet50, and Vgg19 to classify breast lesions after using transfer learning with fine-tuning and training the CNN with regions extracted from the MIAS and INbreast databases. We analyzed 14 classifiers, involving 4 classes as several researches have done it before, corresponding to benign and malignant microcalcifications and masses, and as our main contribution, we also added a 5th class for the normal tissue of the mammary parenchyma increasing the correct detection; in order to evaluate the architectures with a statistical analysis based on the received operational characteristics (ROC), the area under the curve (AUC), F1 Score, accuracy, precision, sensitivity, and specificity. We generate the best results with the CNN GoogLeNet trained with five classes on a balanced database with an AUC of 99.29%, F1 Score of 91.92%, the accuracy of 91.92%, precision of 92.15%, sensitivity of 91.70%, and specificity of 97.66%, concluding that GoogLeNet is optimal as a classifier in a CAD system to deal with breast cancer.

The early and precise identification of the different phenological stages of the bean (Phaseolus vulgaris L.) allows for the determination of critical and timely moments for the implementation of certain agricultural activities that contribute in a significant manner to the output and quality of the harvest, as well as the necessary actions to prevent and control possible damage caused by plagues and diseases. Overall, the standard procedure for phenological identification is conducted by the farmer. This can lead to the possibility of overlooking important findings during the phenological development of the plant, which could result in the appearance of plagues and diseases. In recent years, deep learning (DL) methods have been used to analyze crop behavior and minimize risk in agricultural decision making. One of the most used DL methods in image processing is the convolutional neural network (CNN) due to its high capacity for learning relevant features and recognizing objects in images. In this article, a transfer learning approach and a data augmentation method were applied. A station equipped with RGB cameras was used to gather data from images during the complete phenological cycle of the bean. The information gathered was used to create a set of data to evaluate the performance of each of the four proposed network models: AlexNet, VGG19, SqueezeNet, and GoogleNet. The metrics used were accuracy, precision, sensitivity, specificity, and F1-Score. The results of the best architecture obtained in the validation were those of GoogleNet, which obtained 96.71% accuracy, 96.81% precision, 95.77% sensitivity, 98.73% specificity, and 96.25% F1-Score.

The choice of structural parameters in the design of artificial neural networks is generally based on trial-and-error procedures. They are regularly estimated based on the previous experience of the researcher, investing large amounts of time and processing resources during network training, which are usually limited and do not guarantee the optimal selection of parameters. This paper presents a procedure for the optimization of the training dataset and the optimization of the structural parameters of a neural network through the application of a robust neural network design methodology based on the design philosophy proposed by Genichi Taguchi, applied to the solution of inverse kinematics in an open source, six-degrees-of-freedom robotic manipulator. The results obtained during the optimization process of the structural parameters of the network show an improvement in the accuracy of the results, reaching a high prediction percentage and maintaining a margin of error of less than 5%.