A series of novel indole Schiff base derivatives (2a–2t) containing a 1,3,4-thiadiazole scaffold modified with a thioether group were synthesized, and their structures were confirmed using FT-IR, ¹H NMR, ¹³C NMR, and HR-MS. In addition, the antifungal activity of synthesized indole derivatives was investigated against Fusarium graminearum (F. graminearum), Fusarium oxysporum (F. oxysporum), Fusariummoniliforme (F.moniliforme), Curvularia lunata (C. lunata), and Phytophthora parasitica var. nicotiana (P. p. var. nicotianae) using the mycelium growth rate method. Among the synthesized indole derivatives, compound 2j showed the highest inhibition rates of 100%, 95.7%, 89%, and 76.5% at a concentration of 500 μg/mL against F. graminearum, F. oxysporum, F.moniliforme, and P. p. var. nicotianae, respectively. Similarly, compounds 2j and 2q exhibited higher inhibition rates of 81.9% and 83.7% at a concentration of 500 μg/mL against C. lunata. In addition, compound 2j has been recognized as a potential compound for further investigation in the field of fungicides.

With the rapid development of digital inkjet printing, it will inevitably lead to the uneven quality of inkjet printing ink products on the market. Therefore, making a more comprehensive and accurate quality evaluation of digital printing ink is particularly important. In this study, a short process and environment-friendly washing-free disperse dye ink was prepared based on the research on ink quality. The quality of printing ink is closely related to its physical properties, printing ink stability, inkjet performance, and inkjet printing effect. The microdistribution state of water for washing-free disperse dye ink was analyzed by LF-NMR, and the influence of the microstate of water on the macro physical properties of the ink was clarified. The physical properties (particle size, pH value, surface tension, viscosity, rheological properties, etc.) of the washing-free disperse dye ink were systematically tested and analyzed. At the same time, the stability (weatherability, the temperature sensitivity of viscosity, and shear stability) and inkjet performance (drive waveform A, B, and C) of washing-free disperse dye ink were systematically investigated. Finally, the inkjet printing effect of washing-free disperse dye ink was evaluated. This study systematically examined the quality and printing effect of the prepared washing-free disperse dye ink and provided quality evaluation reference for the development of high-quality washing-free disperse dye ink.

3,n-fused (n = 4–7) tricyclic indoles are pervasive motifs, embedded in a variety of biologically active molecules and natural products. Thus, numerous catalytic methods have been developed for the synthesis of these skeletons over the past few decades. In particular, palladium-catalyzed transformations have received much attention in recent years. This review summarizes recent developments in the synthesis of these tricyclic indoles with palladium-catalyzed domino reactions and their applications in the total synthesis of representative natural products.

A versatile and environmentally friendly method for the synthesis of various organophosphorus compounds have been developed under microware conditions. We have synthesized a series of the trifluoromethyl phosphonates via Phospha-Brook rearrangement between dialkylphosphite and 3-(trifluoroacetyl)coumarins using KF/Al₂O₃ as a highly efficient solid catalyst under solventless conditions. Catalyst reuse, ease of separation of the pure product, and high yields are some of the unique features of this process. In addition, the mycelial growth rate method was used to examine the in vitro antifungal activities of the phosphates 4a-o against Phytophthora capsici, Fusarium oxysporum vasinfectum, Bipolaris maydis and Alternaria solani at 500 µg/mL. The results showed that compound 4n exhibited significant anti-Phytophthora capsici activity with inhibitory index of 86%.