Christos Stefanis

Dr. Christos Stefanis

Medical School, Laboratory of Hygiene and Envrionmental Protection, Democritus University of Thrace, Alexandroúpoli, Anatolikí Makedonía kai Thráki, Greece
orcid

Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 February 2023 in Antioxidants
Verified
Journal Article
Open access
PDF file
CSChristos Stefanis
Christos Stefanis
ESElisavet Stavropoulou
Elisavet Stavropoulou
EGElpida Giorgi
Elpida Giorgi
CVChrysoula (Chrysa) Voidarou
Chrysoula (Chrysa) Voidarou
TCTheodoros Constantinidis Constantinidis
Theodoros Constantinidis Constantinidis
Athanasios TsakrisAthanasios Tsakris
Athanasios Tsakris
Research attention has been drawn to honey’s nutritional status and beneficial properties for human health. This study aimed to provide a bibliometric analysis of honey’s antioxidant and antimicrobial properties. The research advancements within this field from 2001 to 2022 were addressed using the Scopus database, R, and VOSviewer. Of the 383 results, articles (273) and reviews (81) were the most common document types, while the annual growth rate of published manuscripts reached 17.5%. The most relevant topics about honey’s antimicrobial and antioxidant properties were related to the agricultural and biological sciences, biochemistry, and pharmacology. According to a keyword analysis, the most frequent terms in titles, abstracts, and keywords were honey, antimicrobial, antioxidant, bee, propolis, phenolic compounds, wound, antibacterial, anti-inflammatory, and polyphenols. A trend topic analysis showed that the research agenda mainly encompassed antioxidants, pathogens, and anti-infection and chemical agents. In a co-occurrence analysis, antioxidants, anti-infection agents, and chemistry were connected to honey research. The initial research focus of this domain was primarily on honey’s anti-inflammatory and antineoplastic activity, wound healing, and antibacterial agents. The research agenda was enriched in the subsequent years by pathogens, propolis, oxidative stress, and flavonoids. It was possible to pinpoint past trends and ongoing developments and provide a valuable insight into the field of honey research.

12 July 2012 in Folia Microbiologica
Verified
Journal Article
Closed access
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CSChristos Stefanis
Christos Stefanis
AAAthanasios Alexopoulos
Athanasios Alexopoulos
CVChrysoula (Chrysa) Voidarou
Chrysoula (Chrysa) Voidarou
SVStavros Vavias
Stavros Vavias
EBEugenia Bezirtzoglou
Eugenia Bezirtzoglou

30 May 2024 in Sustainability
Verified
Journal Article
Open access
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CSChristos Stefanis
Christos Stefanis
ASAgathangelos Stavropoulos
Agathangelos Stavropoulos
ESElisavet Stavropoulou
Elisavet Stavropoulou
Christina TsigalouChristina Tsigalou
Christina Tsigalou
TCTheodoros Constantinidis Constantinidis
Theodoros Constantinidis Constantinidis
EUGENIA BEZIRTZOGLOUEUGENIA BEZIRTZOGLOU
EUGENIA BEZIRTZOGLOU
This bibliometric study investigates the scientific landscape of environmental sustainability within the European Green Deal (EGD) framework. Utilizing data from the Scopus and Science Direct databases, the study aims to map research trends and frontiers, providing a comprehensive overview of the evolving discourse on sustainability. The EGD’s ambitious goal to render the European Union climate-neutral by 2050 is highlighted, showcasing its significant impact across multiple sectors. The study reveals the integration of new methods and broadening research scopes by employing modern bibliometric techniques. Key thematic focuses include the transition to a circular economy and the emphasis on sustainable resource management, underpinning the EGD’s comprehensive approach to combining economic growth with environmental protection. The analysis unveils the critical role of technological innovation and policy reforms in advancing toward a sustainable, competitive, and climate-neutral economy. The research demonstrates the pivotal role of empirical studies in guiding policy formulation and implementation, showing how targeted measures in resource and energy productivity, combined with a decisive shift towards renewable energy, are integral to fostering a sustainable, competitive, and climate-neutral economy. This convergence of findings reinforces the argument that a multifaceted approach, encompassing policy, technology, and innovation, is essential for navigating the challenges of environmental sustainability and climate change, aligning closely with the overarching aims of the EGD.

8 February 2023 in Biomedicines
Verified
Journal Article
Open access
PDF file
GVGeorgios Vakadaris
Georgios Vakadaris
CSChristos Stefanis
Christos Stefanis
EGElpida Giorgi
Elpida Giorgi
MBMerkourios Brouvalis
Merkourios Brouvalis
CVChrysoula (Chrysa) Voidarou
Chrysoula (Chrysa) Voidarou
EUGENIA BEZIRTZOGLOUEUGENIA BEZIRTZOGLOU
EUGENIA BEZIRTZOGLOU
Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract affecting millions of patients worldwide. The gut microbiome partly determines the pathogenesis of both diseases. Even though probiotics have been widely used as a potential treatment, their efficacy in inducing and maintaining remission is still controversial. Our study aims to review the present-day literature about the possible role of probiotics in treating inflammatory bowel diseases in adults. This research was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. We included studies concerning adult patients who compared probiotics with placebo or non-probiotic intervention. We identified thirty-three studies, including 2713 patients from fourteen countries. The role of probiotics in Crohn’s disease was examined in eleven studies. Only four studies presented statistically significant results in the remission of disease, primarily when used for three to six months. On the other hand, in twenty-one out of twenty-five studies, probiotics proved effective in achieving or maintaining remission in ulcerative colitis. Supplementation with Bifidobacterium sp. or a combination of probiotics is the most effective intervention, especially when compared with a placebo. There is strong evidence supporting the usage of probiotic supplementation in patients with ulcerative colitis, yet more research is needed to justify their efficacy in Crohn’s disease.

23 August 2025 in Discover Applied Sciences
Verified
Journal Article
Open access
PDF file
CSChristos Stefanis
Christos Stefanis
ESElisavet Stavropoulou
Elisavet Stavropoulou
ASAgathangelos Stavropoulos
Agathangelos Stavropoulos
Despoina GyrikiDespoina Gyriki
Despoina Gyriki
Christos G. NikolaidisChristos G. Nikolaidis
Christos G. Nikolaidis
EUGENIA BEZIRTZOGLOUEUGENIA BEZIRTZOGLOU
EUGENIA BEZIRTZOGLOU
Bibliometric analysis is a vital methodological tool for mapping scientific knowledge and identifying research trends. However, challenges in structuring, sorting, and interpreting bibliometric results, as well as a lack of standardized workflows, often hinder their practical application, especially for novice researchers. This study introduces a structured methodological framework that improves the design and interpretability of bibliometric analyses. We propose and discuss four key methodological pillars: (i) formulation of precise research questions to guide design and metrics; (ii) the application of artificial intelligence (AI)-based tools for efficient and unbiased article screening; (iii) the normalization of research output data using economic indicators, such as gross domestic product, to improve cross-country comparisons and (iv) the use of dual-tool analysis—specifically VOSviewer and Biblioshiny—to validate bibliometric findings. This integrated framework improves the transparency, clarity and robustness of bibliometric studies. AI-powered article screening leads to faster and more consistent inclusion decisions. Normalizing bibliometric data based on economic output enhances the interpretability of national research performance. Cross-referencing bibliometric models with two complementary tools allows for a more robust depiction of knowledge structures and emerging themes. In conclusion, the introduction of this methodological framework advances the practice of bibliometric analysis, contributing to a more reliable and informative bibliometric approach.

27 September 2023 in Stats
Verified
Journal Article
Open access
PDF file
CSChristos Stefanis
Christos Stefanis
EGElpida Giorgi
Elpida Giorgi
GTGiorgios Tselemponis
Giorgios Tselemponis
CVChrysoula (Chrysa) Voidarou
Chrysoula (Chrysa) Voidarou
ISIoannis Alexandros Skoufos
Ioannis Alexandros Skoufos
EUGENIA BEZIRTZOGLOUEUGENIA BEZIRTZOGLOU
EUGENIA BEZIRTZOGLOU
This study aimed to perform a bibliometric analysis of terroir and explore its conceptual horizons. Advancements in terroir research until 2022 were investigated using the Scopus database, R, and VOSviewer. Out of the 907 results, the most prevalent document types were articles (771) and reviews (70). The annual growth rate of published manuscripts in this field was 7.8%. The research on terroir encompassed a wide range of disciplines, with significant contributions from Agricultural and Biological Sciences, Social Sciences, Environmental Science, Biochemistry, Genetics, and Molecular Biology. Through keyword analysis, the study identified the most frequently occurring terms in titles, abstracts, and keywords fields, including ‘terroir’, ‘wine’, ‘soil’, ‘wines’, ‘grape’, ‘analysis’, ‘vineyard’, ‘composition’, and ‘climate’. A trend topic analysis revealed that research in terroir primarily focused on the geo-ecology and physiology of grapes. Furthermore, considerable attention was given to methods and techniques related to the physicochemical, sensory, and microbial characterization of terroir and various aspects of the wine industry. Initially, the research in this domain was focused on terroir, authenticity, grapevine, soils, soil moisture, and wine quality. However, over time, the research agenda expanded to include topics such as food analysis, viticulture, wine, taste, sustainability, and climate change. New research areas emerged, including phenolic compounds, anthocyanin, phenols, sensory analysis, and precision agriculture—all of which became integral components of the scientific studies on terroir. Overall, this study provided valuable insights into the historical trends and current developments in terroir research, contributing to our understanding of the frontiers in this field.