Surgical sutures are widely used for closing wounds in skin. However, the monitoring of wound integrity and promoting tissue regeneration at the same time still remains a challenge. To address this, we developed a drug-releasing electronic suture system (DRESS) to monitor the suture integrity in real-time and enhance tissue regeneration by triggered drug release. DRESS was fabricated by using a single fiber with a core–shell structure consisting of a stretchable conductive fiber core and a thermoresponsive polymer shell containing drugs. The highly conductive fiber core acts as a strain sensor that enables continuous monitoring of suture strain with high sensitivity (a gauge factor of ∼686) and mechanical durability (being able to endure more than 3000 stretching cycles). The thermoresponsive shell layer composed of flexible poly(vinyl alcohol) (PVA) grafted onto poly(N-isopropylacrylamide) (PNIPAm) facilitates on-demand drug release via Joule heating. The results of an in vitro scratch assay showed a 66% decrease in wound area upon heat-activation after 48 hours demonstrating the stimuli-responsive therapeutic efficacy of DRESS by promoting cell migration. Moreover, ex vivo testing on porcine skin demonstrated the applicability of DRESS as a electronic suture. The approach used for DRESS provides insight into multifunctional sutures and offers additional therapeutic and diagnostic options for clinical applications.
This paper aims to discuss the key accomplishments and further prospects of active-matrix (AM) quantum-dot (QD) light-emitting diodes (QLEDs) display. We present an overview and state-of-the-art of QLEDs as a frontplane and non-Si-based thin-film transistors (TFTs) as a backplane to meet the requirements for the next-generation displays, such as flexibility, transparency, low power consumption, fast response, high efficiency, and operational reliability. After a brief introduction, we first review the research on non-Si-based TFTs using metal oxides, transition metal dichalcogenides, and semiconducting carbon nanotubes as the driving unit of display devices. Next, QLED technologies are analyzed in terms of the device structure, device engineering, and QD patterning technique to realize high-performance, full-color AM-QLEDs. Lastly, recent research on the monolithic integration of TFT–QLED is examined, which proposes a new perspective on the integrated device. We anticipate that this review will help the readership understand the fundamentals, current state, and issues on TFTs and QLEDs for future AM-QLED displays.
23 December 2024 in ACS Applied Materials & Interfaces
Colloidal quantum dots (QDs) offer size-tunable optoelectronic properties and solution processability, yet achieving uniformly packed emissive layers remains a bottleneck for high-performance quantum-dot light-emitting diodes (QLEDs). Here, we report a machine learning -guided solvent optimization strategy to produce homogeneous QD films. Five representative solvent parameters are evaluated, and multiple regression models are trained against film uniformity derived from atomic force microscopy. Among them, support vector regression provides the highest predictive accuracy for film homogeneity. Guided by these predictions, we formulate a mixed solvent that closely matches the target profile, yielding superior packing homogeneity, which is confirmed by grazing-incidence small-angle x-ray scattering. QLEDs fabricated with this formulation exhibit an external quantum efficiency of 20.6% and an operational lifetime of 468.5 h at 20 000 cd m −2 , surpassing all single-solvent controls. These findings establish packing homogeneity as a decisive factor for device performance and introduce a generalizable and scalable framework for data-driven design of solution-processed devices, holding strong potential for next-generation optoelectronic systems.