Energy consumption in the drying industry has made drying an energy-intensive operation. In this study, the drying time, quality properties (color, shrinkage, water activity and rehydration ratio), specific energy consumption (S.E.C), thermal, energy and exergy efficiency of corn drying using a hybrid dryer convective-infrared-rotary (CV-IR-D) were analyzed. In addition, the energy parameters and exergy efficiency of corn were predicted using the artificial neural network (ANN) technique. The experiments were conducted at three rotary rotation speeds of 4, 8 and 12 rpm, drying temperatures of 45, 55 and 65 °C, and infrared power of 0.25, 0.5 and 0.75 kW. By increasing drying temperature, infrared power and rotary rotation speed, the drying time, S.E.C and water activity decreased while the D_eff, energy, thermal and exergy efficiency increased. In addition, the highest values of rehydration ratio and redness (a*) and the lowest values of shrinkage, brightness (L*), yellowness (b*) and color changes (ΔE) were obtained at an infrared power of 0.5 kW, air temperature of 55 °C and rotation speed of 8 rpm. The range of changes in S.E.C, energy, thermal and exergy efficiency during the corn drying process was 5.05–28.15 MJ/kg, 3.26–29.29%, 5.5–32.33% and 21.22–55.35%. The prediction results using ANNs showed that the R for the drying time, S.E.C, thermal, energy and exergy data were 0.9938, 0.9906, 0.9965, 0.9874 and 0.9893, respectively, indicating a successful prediction.

The use of colchicine to induce polyploids increases secondary metabolite production potential and has been used for many years for the production of valuable compounds in plants. This project took advantage of this method to increase the production of secondary metabolites in licorice. For this purpose, seeds of licorice, Glycyrrhiza glabra var. glandulifera, were treated with different concentrations of colchicine for 24 hours and then cultivated in vitro. After a month, the effect of colchicine on the cellular DNA level of cotyledons was analyzed by spectrophotometry and flow cytometry. For callus induction, root explants of one month old plantlets derived from colchicine treated seeds were transferred to MS medium containing growth regulators and the anthocyanin and glycyrrhizic acid levels of the callus tissues were measured after two months of growth. The total DNA content of plantlets derived from seeds treated with 0.05%, 0.08% and 0.1% of colchicine for 24 hours was increased significantly. Treated plants had increased numbers of larger stomata, significantly in those treated with 0.1% of colchicine for 24 hours. After colchicine treatment, the root, shoot and leaf thickness was found to be increased, while their length was decreased. Results of flow cytometry showed changes in ploidy level in plantlets obtained from treatment with 0.08% (mixoploids) and 0.1% (tetraploids) of colchicine. Anthocyanin level was significantly increased in callus obtained from plantlets treated with 0.08% of colchicine. The amount of glycyrrhizic acid in all treatments increased, especially in the 0.1 and 0.03% colchicine treatments and this seems to prove an increased production of metabolites in polyploid licorice tissues.

Background: Hormonal imbalances related to women's health, physical activity, and fluctuations are prevalent metabolic disorders in several nations and have significantly impacted women's health for an extended period. The application of individual or combined botanical extracts in traditional, alternative, and complementary medicine is employed to manage and alleviate these issues. Objectives: The objective of this study is to examine the suppressive properties of horehound (Marrubium vulgare L.) on pivotal hormones associated with feminine disorders. Methods: The horehound plant was exposed to ultrasonic radiation while five different solvents (methanol, ethyl acetate, n-hexane, acetone, and water) were used to extract its components. The individuals were isolated using high-performance thin-layer chromatography (HPTLC). The most powerful compounds were analyzed using a direct antioxidant assay (DPPH test) and a hormone inhibitory assay (Oestrogen, Progesterone, Estradiol, and Testosterone) on the HPTLC plate. The compounds that had a significant effect were then identified using LC-ESI/MSMS. Results: The antioxidant properties of the extracts and hormone inhibitors were evaluated, and the substances were separated from the HPTLC plate and analyzed using mass spectrometry. The results showed strong antioxidant capabilities, with an IC50 range of 8.24 - 12.42 µg/mL. Moreover, the plant extract showed beneficial effects on hormones associated with female health issues. Conclusions: The extract was subjected to chemical and molecular analysis using the HPTLC technique, followed by LC-ESI/MSMS. The study revealed the presence of vulgarole, marrubiin, and marrubenol chemicals.