The world is facing a global financial loss and health effects due to food quality adulteration and contamination, which are seriously affecting human health. Synthetic colors, flavors, and preservatives are added to make food more attractive to consumers. Therefore, food safety has become one of the fundamental needs of mankind. Due to the importance of food safety, the world is in great need of developing desirable and accurate methods for determining the quality of food. In recent years, the electrochemical methods have become more popular, due to their simplicity, ease in handling, economics, and specificity in determining food safety. Common food contaminants, such as pesticides, additives, and animal drug residues, cause foods that are most vulnerable to contamination to undergo evaluation frequently. The present review article discusses the electrochemical detection of the above food contaminants using different carbon nanomaterials, such as carbon nanotubes (CNTs), graphene, ordered mesoporous carbon (OMC), carbon dots, boron doped diamond (BDD), and fullerenes. The voltammetric methods, such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV), have been proven to be potential methods for determining food contaminants. The use of carbon-based electrodes has the added advantage of electrochemically sensing the food contaminants due to their excellent sensitivity, specificity, large surface area, high porosity, antifouling, and biocompatibility.

Ageing is a complex process that is associated with changes in the composition and functions of gut microbiota. Reduction of gut commensals is the hallmarks of ageing, which favours the expansion of pathogens even in healthy centenarians. Interestingly, gut Enterobacteriaceae have been found to be increased with age and also consistently observed in the patients with metabolic diseases. Thus, they are associated with all-cause mortality, regardless of genetic origin, lifestyle, and fatality rate. Moreover, Enterobacteriaceae are also implicated in accelerating the ageing process through telomere attrition, cellular senescence, inflammasome activation and impairing the functions of mitochondria. However, acceleration of ageing is likely to be determined by intrinsic interactions between Enterobacteriaceae and other associated gut bacteria. Several studies suggested that Enterobacteriaceae possess genes for the synthesis of uraemic toxins. In addition to intestine, Enterobacteriaceae and their toxic metabolites have also been found in other organs, such as adipose tissue and liver and that are implicated in multiorgan dysfunction and age-related diseases. Therefore, targeting Enterobacteriaceae is a nuance approach for reducing inflammaging and enhancing the longevity of older people. This review is intended to highlight the current knowledge of Enterobacteriaceae-mediated acceleration of ageing process.

Globally, breast cancer is one of the most widespread malignancies among women, posing a significant Healthcare challenge that necessitates a comprehensive treatment approach. This paper explores the potential of phytochemicals as therapeutic agents for breast cancer, focusing on their extraction processes, bioavailability challenges, and advancements in drug delivery systems. Phytochemicals, which originate from natural sources, exhibit remarkable bioactivity and can modulate various biochemical pathways involved in cancer progression, making them potential adjuncts or alternatives to conventional therapies. While over 100 phytochemicals with anticancer properties have been identified, only ten have progressed to clinical trials. This limited progress is largely due to challenges in identifying, extracting, and isolating bioactive compounds from crude extracts. Employing in silico approaches alongside advanced extraction technologies can significantly reduce the time required to identify and isolate the therapeutic compounds. However, the therapeutic application of phytochemicals remains constrained by issues such as low solubility, poor absorption, and inadequate tissue penetration. To overcome these limitations, innovative drug delivery systems—particularly nanoparticle-based technologies—are being developed to improve the solubility, bioavailability, and targeted delivery of these compounds. Leveraging advanced delivery methods and maximizing the therapeutic potential of plant-derived bioactive compounds could significantly contribute to the development of effective and sustainable breast cancer treatments.

In this research article we report the potentials of chitin-based silver nanoparticles (chitin AgNPs) derived from Indian mimic goatfish (Mulloidichthys ayliffe) scales as an effective food preservation agent. The study comprehensively presents the multifaceted attributes of chitin AgNPs, including their synthesis, characterization, and antimicrobial properties. Chitin yield from M. ayliffe scales and three-spot swimming crab (P. sanguinolentus) exoskeleton was determined, with the insoluble content quantified. FTIR analysis unveiled distinct absorption peaks for chitin, and scanning electron microscopy revealed the ultrastructure of chitin from both the sources. Using UV–visible spectroscopy, the biosynthesis of AgNPs was accomplished and characterized, with the color shift of the solution serving as proof of a successful synthesis. UV–vis spectra provided insights into nanoparticle size and shape. SEM micrographs exhibited spherical particle morphology, while FTIR spectra indicated amino group interactions contributing to AgNP stabilization. The antimicrobial potential of chitin AgNPs was assessed against the food pathogen, Vibrio spp. Chitin films displayed significant antimicrobial activity, particularly AgNP-synthesized chitin from M. ayliffe scales, demonstrated the highest Vibrio spp. inhibition activity. Furthermore, chitin AgNPs were incorporated into the common chili, Capsicum annuum and the tomato, Solanum lycopersicum to extend their shelf life at room temperature. This study reveals the efficacy of chitin AgNPs from M. ayliffe scales as potent agents for food preservation, offering insights into their physical, mechanical, and antimicrobial attributes. The application of chitin AgNPs to perishable food items highlights their potential in enhancing shelf life and quality, opening innovative avenues for sustainable food preservation.