Jose Aranguren

Dr. Jose Aranguren

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 December 2022 in Applied Sciences
Verified
Journal Article
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Vincenzo ToscoVincenzo Tosco
Vincenzo Tosco
Riccardo MonterubbianesiRiccardo Monterubbianesi
Riccardo Monterubbianesi
JAJose Aranguren
Jose Aranguren
LMLucia Memè
Lucia Memè
Angelo PutignanoAngelo Putignano
Angelo Putignano
Giovanna OrsiniGiovanna Orsini
Giovanna Orsini
Irrigation represents a crucial step in endodontics for bacteria disinfection and smear layer removal. Several irrigation strategies have been proposed, although their effects are controversial. This study aims to assess the comparison of four different irrigation systems on the smear layer removal utilizing scanning electron microscopy (SEM). Forty sound monoradicular teeth were collected and casually allocated into four groups (n = 10): Group A, conventional irrigation; Group B, IrriFlex irrigation; Group C, ultrasonic irrigation system; Group D, apical negative pressure irrigation. After chemo-mechanical preparation and longitudinal root separation, the three root thirds were analyzed by SEM. Micrographs were carried out at ×2000 to analyze the smear layer residual in each third of the root canal. Statistically significant differences were found between Group A and Group D (p < 0.05). Groups B and C showed satisfactory results in the coronal and middle thirds, while Group D was the only system that achieved satisfactory results in the apical third. However, the complete smear layer removal in the root canal was never achieved with any of the four systems tested. In conclusion, among the four tested irrigation systems, the greatest efficacy on smear layer removal was reached by Group D.

30 October 2024 in Materials
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Journal Article
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RARamírez Muñoz Ana
Ramírez Muñoz Ana
MEMarta Escribano-Capdevila
Marta Escribano-Capdevila
NMNATALIA NAVARRETE MARABINI
NATALIA NAVARRETE MARABINI
GVGaya C. S. Vieira
Gaya C. S. Vieira
MSMarcela Salamanca
Marcela Salamanca
Alejandro R. PérezAlejandro R. Pérez
Alejandro R. Pérez
(1) Background: This study aimed to compare the shaping abilities of modern minimally invasive endodontic systems using natural teeth and 3D-printed resin replicas. These replicas offer a standardized approach for studying root canal preparation while eliminating the variability and scarcity of natural teeth. (2) Methods: Eleven mandibular molars with Vertucci class IV anatomy and their 3D-printed replicas (n = 132 canals) were scanned using micro-CT before and after preparation with six rotary systems. Shaping abilities were assessed by comparing volume, surface area, and unprepared areas between natural teeth and their 3D replicas, focusing on the apical third. Statistical analysis included the Shapiro–Wilk test to assess data normality and ANOVA and t-tests to compare different endodontic systems. (3) Results: Both qualitative and quantitative analyses revealed high similarity between natural teeth and 3D replicas. No significant differences in volume or surface area were found except in the apical third, where 3D replicas showed slightly larger increases in volume. (4) Conclusions: 3D resin replicas closely mimic natural teeth and provide a practical tool for assessing the shaping abilities of endodontic systems. This study demonstrates that 3D-printed models are suitable for endodontic research, offering a standardized and accessible alternative to natural teeth.

21 February 2025 in Materials
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Journal Article
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MSMarcela Salamanca
Marcela Salamanca
JAJose Aranguren
Jose Aranguren
GMGiulia Malvicini
Giulia Malvicini
CGCesar De Gregorio
Cesar De Gregorio
CBCarmen Bonilla
Carmen Bonilla
Alejandro R. PérezAlejandro R. Pérez
Alejandro R. Pérez
This study aimed to analyze the effect of 1% sodium hypochlorite (NaOCl) solution at different temperatures on endodontic file resistance to cyclic fatigue. A total of 90 files, Reciproc NiTi M-Wire® (REC) (n = 30), WaveOne Gold® (WOG) (n = 30), and Reciproc Blue® (RB) (n = 30) were activated under constant irrigation with 1% NaOCl at 5, 37, and 60 °C in a stainless-steel artificial canal (curvature angle = 60°; radius = 5 mm). The time to the fracture and the maximum and minimum load were recorded for each instrument, and data were subjected to statistical analysis. A higher number of cycles to fracture at 5 °C was observed between WOG and RB compared to the REC system (p < 0.05). The RB files were more resistant to cyclic fatigue fracture at 60 °C than WOG and REC (p < 0.05). No statistically significant differences were found between the mean values of the three file types used at 37 °C. The high temperature of NaOCl significantly affects the lifespan of endodontic files, making them more prone to fractures due to cyclic fatigue. The files manufactured with heat treatment showed a longer life than M-wire reciproc files.

30 September 2024 in Materials
Verified
Journal Article
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JAJose Aranguren
Jose Aranguren
FOFelipe Oliveros-Porras
Felipe Oliveros-Porras
RARamírez Muñoz Ana
Ramírez Muñoz Ana
IPIrene Pérez
Irene Pérez
MSMarcela Salamanca
Marcela Salamanca
Alejandro R. PérezAlejandro R. Pérez
Alejandro R. Pérez
This study aims to compare the cyclic fatigue resistance of nickel–titanium (NiTi) endodontic instruments, focusing on the impact of various alloy treatments and manufacturing processes across different generations of these instruments; Twenty instrumentation systems from different generations, comprising both continuous and reciprocating motion designs, were tested. Four hundred instruments underwent cyclic fatigue testing using an INSTRON machine, with the time and number of cycles to fracture (NCF) recorded for each instrument. Statistical analyses were performed to compare the fatigue resistance between systems, generations, and motion types; Instruments treated with advanced thermal processing, such as Excalibur, Reciproc Blue, and TruNatomy, demonstrated superior resistance to fracture, whereas systems like Protaper Universal, K3XF, and 2Shape showed the lowest resistance. Reciprocating instruments generally exhibited higher cyclic fatigue resistance than continuously rotating instruments; Technological advancements in NiTi instrument design, especially the implementation of heat-treated alloys, have improved cyclic fatigue resistance, enhancing the safety and efficiency of endodontic treatments. Reciprocating systems, in particular, exhibit superior fracture resistance, suggesting their greater utility in challenging clinical conditions.

27 November 2025 in Dentistry Journal
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Journal Article
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RPRocío Piñas-Alonzo
Rocío Piñas-Alonzo
Alejandro R. PérezAlejandro R. Pérez
Alejandro R. Pérez
JAJose Aranguren
Jose Aranguren
GVGaya C. S. Vieira
Gaya C. S. Vieira
JPJuan Carlos Paz
Juan Carlos Paz
GMGiulia Malvicini
Giulia Malvicini
Background/Objectives: The objective of this study was to investigate current endodontic practice patterns and the adoption of newer technologies among dentists, endodontic specialists, and postgraduate students in Spain and Latin America. Methods: A cross-sectional survey was conducted using a structured 30-item questionnaire covering demographics, training, technology adoption (NiTi instrumentation, magnification, CBCT, irrigation adjuncts, bioceramic sealers), obturation techniques, irrigant selection, and clinical procedures. The survey was distributed through a professional Instagram account and WhatsApp groups of dentists, specialists, and postgraduate students. Participation was voluntary, anonymous, and restricted to qualified professionals. Data were collected via Google Forms, cleaned, and grouped into Spain, Mexico, Venezuela, Colombia, Southern Cone & Andes (Argentina, Chile, Peru, Ecuador, Bolivia), and other countries. Descriptive statistics were calculated, and intergroup comparisons were performed using Chi-square or Fisher’s exact tests with Bonferroni correction (p < 0.05). Multiple regression analyses were performed. Results: A total of 1358 valid responses were analyzed, distributed as follows: Spain (219), Mexico (353), Venezuela (162), Colombia (108), Southern Cone & Andes (260), and other countries (256). Most respondents (62.8%) had ≤10 years of experience, and 61.2% reported postgraduate training. Loupes (55.4%) were the most frequent magnification system, followed by microscopes (18.6%). Sodium hypochlorite (98.3%) was the irrigant of choice, commonly used with EDTA (83.5%) and, to a lesser extent, chlorhexidine (33.4%). Sonic (83.2%) and ultrasonic (52.9%) activation were frequent. Bioceramic sealers were used by 18.9%, while calcium hydroxide medication was applied by 37.4%. Specialists and master-level clinicians showed greater use of rotary NiTi systems, CBCT, magnification, and bioceramic sealers, whereas general practitioners relied more on manual instrumentation and single-cone obturation. Success was mainly verified by combined clinical and radiographic evaluation (86.7%). Spain demonstrated higher adoption of microscopes, warm vertical compaction, and CBCT. Conclusions: Core practices such as sodium hypochlorite irrigation and rubber dam use were widespread, while advanced technologies and irrigant protocols varied with training level and region. Continuous education remains essential to promote evidence-based practice and reduce disparities in endodontic innovation.

15 August 2025 in Dentistry Journal
Verified
Journal Article
Open access
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Jesus A. AparicioJesus A. Aparicio
Jesus A. Aparicio
PSPedro M. Mendez S
Pedro M. Mendez S
GMGiulia Malvicini
Giulia Malvicini
SGSimone Grandini
Simone Grandini
CGCarlo Gaeta
Carlo Gaeta
Alejandro R. PérezAlejandro R. Pérez
Alejandro R. Pérez
Objectives: This study aimed to compare the clinical durability, mechanical performance, and stress behavior of three NiTi rotary systems—BlueShaper (Blue), BlueShaper Pro (Dual Wire), and BlueShaper Gold (fully gold-treated NiTi)—through a multimodal evaluation that included simulated instrumentation in 3D-printed replicas, mechanical testing, and finite element analysis (FEA). Methods: Sixty instruments (n = 20 per group) were tested. Simulated canal preparation was conducted in standardized 3D-printed mandibular molars with a 40° mesial root curvature until fracture occurred. Mechanical tests included torsional and flexural loading using a universal testing machine and stainless steel blocks with a standardized 40° curvature. FEA simulations evaluated von Mises stress, shear stress, total deformation, cyclic fatigue behavior, and contact pressure between the instrument and canal wall. Results: BlueShaper Gold prepared an average of 7.5 canals before fracture, followed by BlueShaper Pro (5.67 canals) and Blue (5.00 canals) (p < 0.001). Gold exhibited the highest torsional resistance (6.08 ± 3.08 N) and the longest fatigue life (325 ± 55.7 cycles), with the lowest von Mises stress and damage factor in FEA. BlueShaper Pro showed the longest time to fracture in mechanical testing (73.85 ± 7.10 s) and balanced mechanical behavior. Blue demonstrated the lowest performance across most parameters, including the shortest fatigue life and highest stress concentration. Conclusions: BlueShaper Gold exhibited the highest mechanical strength and fatigue resistance. BlueShaper Pro demonstrated the longest fatigue life and balanced mechanical behavior. Blue showed the lowest performance across most parameters. The strong correlation among clinical, mechanical, and FEA data reinforces the critical role of alloy composition in determining instrument durability, even when design remains constant.