In recent years, studies that investigate the effects of chemical compounds on organisms have increased in direct proportion to their widespread use. In this study, four different bidentate imine ligands and bidentate imine ligands+Cu(II) complexes were synthesized from the bioactive synthetic diarylmethylamine compound. After the ligands and metal complexes obtained were purified using chromatographic and analytical methods, their mutagenic effects were investigated with the Ames/Salmonella test system. In addition, interactions of four different Cu(II) complexes with B-DNA were evaluated with molecular docking analysis. Accordingly, the results indicated a significant increase in the colonies formed in the presence (+S9) and absence (-S9) of the metabolic activation system, meaning a mutagenic effect against strain TA98 and TA100 strains in general.

Bartholin gland cysts are common masses in the vulvar region that can range from asymptomatic to large and infected, requiring treatment [1]. In this case report, we wanted to discuss a case of a large Bartholin gland cyst that presented with painful genital swelling to our clinic and its treatment. A woman in perimenopausal age presented with a large mass in the vulva, and physical examination revealed an 18x10 cm mass originating from the left labia minora. MRI confirmed the mass, and the initial diagnosis was Bartholin gland cyst. The cyst was surgically excised totally under the operating room conditions and sent for histopathological examination. Although Bartholin gland cysts can present in various sizes and clinical features, cysts of this size are rare and can be confused with malignant masses.

Background: The aim of this study was to compare maternal and neonatal birth outcomes in pregnant women who re-ceived epidural anesthesia during labor and those who did not.Methods: The study included 129 term pregnant women. The women were divided into two groups based on whether they received epidural anesthesia (Epidural group: n=57, Control group: n=72). Demographic characteristics, delivery times, maternal outcomes (mode of delivery, episiotomy, hemoglobin decrease), and neonatal outcomes such as birth weight, APGAR scores, and neonatal intensive care requirements were retrospectively evaluated.Results: No significant differences were found between the groups in terms of age (24.40±5.09 vs 25.61±5.68, p>0.05) and gestational age (38.65±1.40 vs 38.69±1.47, p>0.05). The second stage of labor was significantly longer in the epidural anesthesia group (38.18±25.50 min vs 24.27±13.50 min, p=0.001). The episiotomy rate was higher in the epidural anes-thesia group (61.4% vs. 51.4%). Birth weight (3230.73±438.89 g vs. 3208.60±384.86 g), 1-minute APGAR score (8.40±0.74 vs 8.43±0.65), and 5-minute APGAR score (9.47±0.66 vs 9.44±0.65). Hemoglobin decrease was similar in both groups (1.44±0.97 g/dL vs 1.41±0.81 g/dL).Conclusions: Epidural anesthesia prolongs the second stage of labor and was not independently associated with in-creased episiotomy rates. However, it has no adverse effect on neonatal outcomes and is safe in terms of maternal bleed-ing. Epidural anesthesia can be used as an effective and safe option for labor pain management.

OBJECTIVE: The aim of this study was to compare body perception during sexual intercourse in pregnant women according to trimesters. MATERIAL and METHODS: This descriptive and comparative study was conducted in the Obstetrics and Gynecology Outpatient Clinic of a training and research hospital in southeastern Türkiye between April and October 2024 with 183 pregnant women selected by random sampling method. “Personal Information Form” and ‘(Body Exposure During Sexual Activities Questionnaire (BESAQ))’ were used as data collection tools. Data were analyzed with Mann Whitney-U, Kruskal Wallis and Spearman correlation tests. Dunn’s test was used for further analysis. RESULTS: The mean BESAQ scores of pregnant women were found to be 1st trimester (1.54±0.42), 2nd trimester (1.51±0.51) and 3rd trimester (1.46±0.58). In the study, no statistically significant difference was observed between the mean scores of pregnant women according to trimesters (p>0.05). CONCLUSION: In the study, although there was no significant difference in the way pregnant women perceived the body during sexual intercourse according to trimesters, it was found that the anxiety levels of pregnant women in each trimester due to focusing on body images during sexual intercourse were below the average. It was recommended that healthcare professionals should have in-depth knowledge about the changes in body perception of pregnant women during sexual intercourse in each trimester and provide evidence-based healthcare services. Keywords: pregnancy, body perception, sexual intercourse, sexuality, nursing