Background/Objectives: This literature review aims to provide guidance on the treatment of recurrent aphthous stomatitis (RAS) based on studies published over the past 10 years. Methods: This study included randomized clinical trials involving human patients from 2013 and 2023, published in any language. The trials examined both pharmacological and non-pharmacological treatments for aphthous lesions, mainly focusing on the adult population, with pain management as the primary outcome. The research was conducted using PubMed, EMBASE, and CINHAL databases. Results: Most of the 45 analyzed studies focused on non-pharmacological therapies, which led to positive results with minimal adverse effects or contraindications, even when compared to cortisone-based treatments. Laser therapy also showed excellent results, particularly in the immediate post-treatment period. Non-pharmacological therapies appeared to offer the best risk–benefit ratio for patients suffering from RAS. Conclusions: Treatment should be individualized based on the patient’s specific form of RAS, and laser therapy can be used either as a standalone treatment or as an adjunct to other treatments considered in the review.

This retrospective study aimed to evaluate a possible correlation between the characteristics of the mandibular ramus and lower third molar impaction by comparing a group of subjects with an impacted lower third molar and a second group with normal eruption for an early prediction of this pathology. This comparison was made using linear and angular measurements, which were taken on digital panoramic radiographs. Materials and methods: A total of 726 orthopantomographs (OPT) were examined, and 81 were considered suitable for the present study. The results were divided into two groups: a control group and an experimental group. The control group comprised 38 cases in which patients had at least one lower third molar that had erupted, and the experimental group comprised 43 cases in which patients had at least one lower third molar that was impacted or partially impacted. In total, 16 variables (11 linear, 4 angular, and 1 ratio) were determined and measured by an experienced observer. Results: The control group had a larger retromolar space, a larger impaction angle and a higher ratio of retromolar area to the third molar, compared to the experimental group. In contrast, the experimental group showed a deeper sigmoid notch depth than the control group did. In the control group, moderate positive correlations were found between both the length of the coronoid and the width of the third molar, and the retromolar space. Furthermore, in the experimental group, moderate positive correlations were found between both the angular condyle–coronoid process and the inclination of the lower posterior teeth, and the retromolar space. Conclusion: this study showed that the angle of a lower third molar, in relation to mandibular pain, can be an index for predicting tooth inclusion.