Kairat Saparkhanovich Zhakipbekov

Prof. Dr. Kairat Saparkhanovich Zhakipbekov

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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12 January 2024 in Molecules
Verified
Journal Article
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KZKairat Saparkhanovich Zhakipbekov
Kairat Saparkhanovich Zhakipbekov
ATAknur Turgumbayeva
Aknur Turgumbayeva
SASholpan Akhelova
Sholpan Akhelova
KBKymbat Bekmuratova
Kymbat Bekmuratova
OBOlga Blinova
Olga Blinova
ZKZhanylsyn Karasova
Zhanylsyn Karasova
Since ancient times, various scientists and doctors have utilized different herbs to heal diseases. Due to the rise in drug resistance and the negative effects of chemosynthetic drugs, researchers and the general public around the world have become more interested in medicinal herbs and plant metabolites/extracts. This is due to its non-toxicity and its several health benefits when used to treat diseases in clinical and medical settings. Ocimum basilicum is one such plant, possessing a wide range of bioactive phytochemicals including alkaloids, phenolics, flavonoids, tannins, saponins, reducing sugars, cardiac glycosides, steroids and glycosides, as well as complex pharmacological activities, including anti-inflammatory, antifungal, antibacterial, antioxidant, wound healing and antiviral properties. The results of many studies on Ocimum basilicum plant extracts are collected and presented in this review. The plant extracts have excellent potential to be used as medicinal raw materials, and exhibit an extensive variety of therapeutic capacities, including antibacterial, antioxidant, wound healing, anti-inflammatory, antifungal, and antiviral properties.

1 August 2023 in Pharmaceuticals
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Journal Article
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KZKairat Saparkhanovich Zhakipbekov
Kairat Saparkhanovich Zhakipbekov
ATAknur Turgumbayeva
Aknur Turgumbayeva
IIIssayeva Issayeva
Issayeva Issayeva
AKAliya Kipchakbayeva
Aliya Kipchakbayeva
GKGulnara Kadyrbayeva
Gulnara Kadyrbayeva
YTYerbol Tileuberdi
Yerbol Tileuberdi
Since ancient times, many scientists and doctors have used various herbs to treat diseases. Conventional drugs often have side effects, and pathogens are becoming resistant to these types of drugs. In such circumstances, the study of traditional medicinal plants is an effective and logical strategy for finding new herbal medicines. One such herb is Plantago major, a perennial plant in the Plantaginaceae family that is found throughout the world. The Plantago major plant has been used as a medicine for the treatment of various diseases. Studies have shown that plant extracts of Plantago major exhibit antimicrobial, antiviral, and anti-inflammatory effects, and have wound-healing properties. This review collects and presents the results of various studies of Plantago major plant extracts with antimicrobial, antiviral, antifungal, anti-inflammatory, and wound-healing properties, which demonstrate a wide range of therapeutic possibilities of Plantago major plant extracts and have a huge potential for use as a medicinal raw material.

31 May 2023 in Molecules
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ZSZhanybek Shegebayev
Zhanybek Shegebayev
ATAknur Turgumbayeva
Aknur Turgumbayeva
DMDatkhayev Ubaidilla Makhambetovich
Datkhayev Ubaidilla Makhambetovich
KZKairat Saparkhanovich Zhakipbekov
Kairat Saparkhanovich Zhakipbekov
AKAssem Kalykova
Assem Kalykova
KOKulpan Orynbassarova
Kulpan Orynbassarova
The genus Anabasis is a member of the family Amaranthaceae (former name: Chenopodiaceae) and includes approximately 102 genera and 1400 species. The genus Anabasis is one of the most significant families in salt marshes, semi-deserts, and other harsh environments. They are also renowned for their abundance in bioactive compounds, including sesquiterpenes, diterpenes, triterpenes, saponins, phenolic acids, flavonoids, and betalain pigments. Since ancient times, these plants have been used to treat various diseases of the gastrointestinal tract, diabetes, hypertension, and cardiovascular diseases and are used as an antirheumatic and diuretic. At the same time, the genus Anabasis is very rich in biologically active secondary metabolites that exhibit great pharmacological properties such as antioxidant, antibacterial, antiangiogenic, antiulcer, hypoglycemic, hepatoprotective, antidiabetic, etc. All of the listed pharmacological activities have been studied in practice by scientists from different countries and are presented in this review article to familiarize the entire scientific community with the results of these studies, as well as to explore the possibilities of using four plant species of the genus Anabasis as medicinal raw materials and developing medicines based on them.

5 December 2022 in Pharmacia
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ATAknur Turgumbayeva
Aknur Turgumbayeva
KZKairat Saparkhanovich Zhakipbekov
Kairat Saparkhanovich Zhakipbekov
ZSZhanar Shimirova
Zhanar Shimirova
SASholpan Akhelova
Sholpan Akhelova
AAAkerke Amirkhanova
Akerke Amirkhanova
DADaniyar Abdambayev
Daniyar Abdambayev
Leaves of Plantago major have been used for centuries to treat diseases relating to skin, digestive organs and blood circulation like wounds, inflammation and hypertension. P. major leaves contain biologically active substance and naturally compounds such as essential oils, minerals and amino acids beside polysaccharides, lipids, caffeic acid and its derivatives, iridoid glycosides, flavonoids and terpenoids. This work carried out an examination of Plantago major leaves in terms of phytochemical composition of methanol extract. The leaves contents in chosen nutrients, specifically amino acids and minerals, are moreover depicted. Gas Chromatography -Mass Spectrometry analysis identified the presence of 31 phytochemical compounds and a total amount of 20 amino acids (essential and nonessential) justifying its use as drugs and biological active supplements and its mineral content showed the presence of 7 essential chemical elements in Plantago major leaves. Nonetheless, additional research into this plant is needed because it has the potential to be used to development of new drugs and biological active supplements.

24 March 2024 in Fitoterapia
Verified
Journal Article
Closed access
BOBotagoz A. Omarova
Botagoz A. Omarova
Elvira ShultsElvira Shults
Elvira Shults
KZKairat Saparkhanovich Zhakipbekov
Kairat Saparkhanovich Zhakipbekov
АAАssima О. Abekova
Аssima О. Abekova
MIMargarita Yu Ishmuratova
Margarita Yu Ishmuratova
EKElmira B. Kartbayeva
Elmira B. Kartbayeva

22 April 2022 in International Journal of Biomaterials
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MTMeruyert Tleubayeva
Meruyert Tleubayeva
RARaisa M. Abdullabekova
Raisa M. Abdullabekova
UDUbaidilla Datkhayev
Ubaidilla Datkhayev
MIMargarita Yulaevna Ishmuratova
Margarita Yulaevna Ishmuratova
MAMereke Alimzhanova
Mereke Alimzhanova
EFElena V. Flisyuk
Elena V. Flisyuk
Medicinal plants remain as an important resource in the fight against many diseases, especially in developing countries. Antioxidants are substances capable of delaying, retarding, and preventing the oxidation of lipids or substances that delay or prevent free radical reactions during lipid oxidation. Natural antioxidants such as ascorbic acid, tocopherol, phenolic compounds, and flavonoids are a safe alternative to chemical antioxidants. In present work, results of antioxidant activity of raw materials from the cultivated plant Portulaca oleracea are presented. The extraction time was optimized to 780 minutes; the yield of extractive substances was 1.25 in the production of CO2 extract under subcritical conditions. For the first time, the antioxidant activity of Portulaca oleracea CO2 extract was determined by the amperometric method. Gas chromatography-mass spectrometry (GC-MS) chemical analysis of Portulaca oleracea CO2 extract dissolved in hexane revealed 37 components, including a complex mixture of aldehydes, alkanes, alkenes, esters, diterpenes, steroids, vitamin E, and carbohydrates. The investigation results showed that the Portulaca oleracea CO2 extract was promising for pharmaceutical, cosmetic, and food industries and had great potential for the prevention and treatment of diseases caused by oxidative stress.