César I. Hernández Vázquez

César I. Hernández Vázquez

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 October 2022 in Fibres & Textiles in Eastern Europe
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JJJagoda Jóźwik-Pruska
Jagoda Jóźwik-Pruska
PBPatrycja Bobowicz
Patrycja Bobowicz
CVCésar I. Hernández Vázquez
César I. Hernández Vázquez
MSMagdalena Szalczyńska
Magdalena Szalczyńska
The paper describes the results of research on consumer awareness and attitudes in the field of the ecology and labelling of packaging products. The research was divided into two parts. The first one was related to the perception of the respondents regarding ecology, while the second one was related to the classification of the cosmetics packaging products presented. The results obtained were analysed statistically. The correlation analysis performed showed the existence of a relationship between the variables selected (consumer attitudes). Strong correlations were noticed. The research showed that consumers equate labelling to the properties of products and packaging. The labelling of packaging and products can be ambiguous, which results in a problem with classifying waste to the appropriate segregation and collection system.

9 August 2025 in Marine Drugs
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MKMarcin Henryk Kudzin
Marcin Henryk Kudzin
AKAnna Magdalena Kaczmarek
Anna Magdalena Kaczmarek
ZMZdzisława Mrozińska
Zdzisława Mrozińska
CVCésar I. Hernández Vázquez
César I. Hernández Vázquez
KPKlaudia Piekarska
Klaudia Piekarska
PKPaulina Król
Paulina Król
Alginate-based materials are widely studied for biomedical use, but their limited mechanical properties and variable biocompatibility pose challenges. In this work, hybrid composites composed of alginate, calcium, and graphene oxide were fabricated using a freeze-drying method and cross-linked with calcium ions via calcium chloride at different concentrations. Structural and morphological features were assessed using SEM, EDS, ICP-MS, and BET analysis. The resulting composites exhibited a porous architecture, with calcium incorporation confirmed by elemental analysis. Surface characteristics and pore parameters were influenced by the presence of graphene oxide and the cross-linking process. The effects of the materials on haemostasis were evaluated through activated partial thromboplastin time (aPTT) and prothrombin time (PT) assays, revealing modulation of the intrinsic coagulation pathway without significant changes in the extrinsic pathway. In this study, we analysed the effect of alginate–graphene oxide composites on the viability of peripheral blood mononuclear (PBM) cells and human foreskin fibroblasts from the Hs68 cell line. We also assessed the genotoxic potential of alginate–graphene oxide composites on these cells. Our results showed no cyto- or genotoxic effects of the material on either cell type. These findings suggest the biocompatibility and safe character of alginate–graphene oxide composites for use with blood and skin cells.

7 February 2024 in Polymers
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CVCésar I. Hernández Vázquez
César I. Hernández Vázquez
ZDZbigniew Draczyński
Zbigniew Draczyński
DBDominik Borkowski
Dominik Borkowski
DKDorota Kaźmierczak
Dorota Kaźmierczak
Chitosan, a well-established biomaterial known for its biocompatibility, biodegradability, and bioactivity, has been the focus of extensive research in recent years. This study explores the enhancement of chitosan fibers’ properties through wet impregnation with either ursolic acid (UA) or cross-linking with tripolyphosphate (TPP). In the first experiment, chitosan fibers were treated with UA, for varying immersion set points (1, 2, 4, 6, and 8 h). FTIR, SEM, and UV-Vis spectroscopy analyses demonstrated a chemical reaction between chitosan and UA, with stability reached after 2 h of immersion. Antibacterial testing revealed that chitosan fibers impregnated with UA exhibited significant antibacterial activity against Gram-positive bacteria, notably Staphylococcus aureus. The second experiment involved modifying chitosan fibers’ surfaces with a 1% w/v TPP solution for the same periods of time (1, 2, 4, 6, and 8 h). Subsequently, the investigation involved FTIR, SEM, and dynamometry analyses, which revealed successful cross-linking between chitosan and TPP ions, resulting in improved tensile strength after 2 h of immersion. This dual-approach study highlights the potential of chitosan fibers for diverse applications, from wound-healing dressings to antibacterial materials against Gram-positive bacteria.

10 September 2024 in Marine Drugs
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MŚMałgorzata Świerczyńska
Małgorzata Świerczyńska
PKPaulina Król
Paulina Król
CVCésar I. Hernández Vázquez
César I. Hernández Vázquez
KPKlaudia Piekarska
Klaudia Piekarska
KWKatarzyna Wozniak
Katarzyna Wozniak
MKMarcin Henryk Kudzin
Marcin Henryk Kudzin
The aim of this research was to synthesize and characterize alginate–calcium composites using a freeze-drying method, with a focus on their potential applications in biomedicine. This study specifically explored the biochemical properties of these composites, emphasizing their role in blood coagulation and their capacity to interact with DNA. Additionally, the research aimed to assess how the cross-linking process influences the structural and chemical characteristics of the composites. Detailed analyses, including microscopic examination, surface area assessment, and atomic absorption spectrometry, yielded significant results. The objective of this study was to examine the impact of calcium chloride concentration on the calcium content in alginate composites. Specifically, the study assessed how varying concentrations of the cross-linking solution (ranging from 0.5% to 2%) influence the calcium ion saturation within the composites. This investigation is essential for understanding the physicochemical properties of the materials, including calcium content, porosity, and specific surface area. The results are intended to identify the optimal cross-linking conditions that maximize calcium enrichment efficiency while preserving the material’s structural integrity. The study found that higher calcium chloride concentrations in alginate cross-linking improve the formation of a porous structure, enhanced by two-stage freeze-drying. Increased calcium levels led to a larger surface area and pore volume, and significantly higher calcium content. Furthermore, assays of activated partial thromboplastin time (aPTT) showed a reduction in clotting time for alginate composites containing calcium ions, indicating their potential as hemostatic agents. The aPTT test showed shorter clotting times with higher calcium ion concentrations, without enhanced activation of the extrinsic clotting pathway. The developed alginate material with calcium effectively supports hemostasis and reduces the risk of infection. The study also explored the capacity of these composites to interact with and modify the structure of plasmid DNA, underscoring their potential for future biomedical applications.

17 May 2023 in Preprints.org
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CVCésar I. Hernández Vázquez
César I. Hernández Vázquez
ZDZbigniew Draczyński
Zbigniew Draczyński
Chitosan's favourable characteristics, such as biocompatibility, biodegradability, and bioactivity, have made it a popular biomaterial and the subject of numerous studies over the last years. This study investigates the enhancement of mechanical properties of chitosan fibres through wet impregnation using tripolyphosphate (TPP) as cross-linker. A 1% w/v solution of TPP was prepared and five separate chitosan fibre specimens were immersed individually in TPP solution for varying times (1, 2, 4, 6, and 8 hours). The specimens were then characterized using FTIR, SEM, and dynamometry to evaluate their physical, chemical, and mechanical properties. The FTIR results indicated successful interaction between the protonated amine groups of chitosan and TPP ions, with the crosslinking reaction reaching completion after 2 hours of immersion. SEM images showed that the surface of the fibres became rougher after the crosslinking reaction, suggesting the formation of new chemical bonds. Mechanical testing revealed a significant improvement in tensile strength for the treated samples compared to untreated ones, indicating successful strengthening through crosslinking. The fibres demonstrate significant potential for use in wound healing dressings.

13 January 2026 in Macromol
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AKAnna Magdalena Kaczmarek
Anna Magdalena Kaczmarek
MKMarcin Henryk Kudzin
Marcin Henryk Kudzin
MJMichał Juszczak
Michał Juszczak
KWKatarzyna Wozniak
Katarzyna Wozniak
PKPaulina Król
Paulina Król
Jerzy J. ChruścielJerzy J. Chruściel
Jerzy J. Chruściel
Fibrous polycaprolactone-based composite materials with the addition of hardystonite (1, 3, and 5 wt.%) were developed using the electrospinning method. The obtained PCL and PCL-HT nonwovens were evaluated in terms of their physiochemical properties (SEM, EDS, BET, and zeta potential). Furthermore, the antioxidant potential [measured by thiobarbituric acid reactive substance (TBARS) levels], blood plasma coagulation parameters, and cyto- and genotoxicity towards PBM and Hs68 cells were assessed to determine the biochemical activity of the composites. The conducted experiments confirmed that hardystonite was successfully incorporated into the PCL matrix. No substantial changes in the fibres’ surface morphology and the structure of the composites were observed. Similarly, the specific surface area, total pore volume, and average pore size did not change significantly. The addition of hardystonite to the polymer solution resulted in a shift in zeta potential toward less negative values. With regard to plasma coagulation parameters, no significant changes were observed in the aPTT, PT, or TT, likely due to the counterbalancing effect of Zn2+ and Ca2+ ions. Furthermore, the PCL-HT composites exhibited a lowered TBARS level, suggesting antioxidant properties, which could be attributed to the presence of zinc in hardystonite. The PCL and PCL-HT composites demonstrated no cytotoxic or genotoxic effects on the tested blood or skin cell types, suggesting their safety.