Mao-Hung Liao

Dr. Mao-Hung Liao


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Verified
Journal Article
Open access
PDF file
CWChieh-Chen Wu
Chieh-Chen Wu
MLMao-Hung Liao
Mao-Hung Liao
Chun-Hsien SuChun-Hsien Su
Chun-Hsien Su
TPTahmina Nasrin Poly
Tahmina Nasrin Poly
MLMing-Chin Lin
Ming-Chin Lin
The prevalence of dementia among the elderly is high, and it is the leading cause of death globally. However, the relationship between benzodiazepine use and dementia risk has produced inconsistent results, necessitating an updated review of the evidence. To address this, we conducted an umbrella review of meta-analyses to summarize the available evidence on the association between benzodiazepine use and dementia risk and evaluate its credibility. We systematically evaluated the meta-analyses of observational studies that examined the connection between benzodiazepine use and dementia risk. For each meta-analysis, we collected the overall effect size, heterogeneity, risk of bias, and year of the most recent article and graded the evidence based on pre-specified criteria. We also used AMSTAR, a measurement tool to evaluate systematic reviews, to assess the methodological quality of each study. Our review included five meta-analyses encompassing 30 studies, and the effect size of the association between benzodiazepine use and dementia risk ranged from 1.38 to 1.78. Nonetheless, the evidence supporting this relationship was weak, and the methodological quality of the studies included was low. In conclusion, our findings revealed limited evidence of a link between benzodiazepine use and dementia risk, and more research is required to determine a causal connection. Physicians should only prescribe benzodiazepine for appropriate indications.

15 March 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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CWChieh-Chen Wu
Chieh-Chen Wu
MLMao-Hung Liao
Mao-Hung Liao
Woon‑Man KungWoon‑Man Kung
Woon‑Man Kung
YWYao-Chin Wang
Yao-Chin Wang
Previous epidemiological studies have raised the concern that the use of proton pump inhibitors (PPIs) is associated with an increased risk of kidney diseases. To date, no comprehensive meta-analysis has been conducted to assess the association between PPIs and the risk of chronic kidney disease (CKD). Therefore, we conducted a systematic review and meta-analysis to address the association between PPIs and CKD. The primary search was conducted in the most popular databases, such as PubMed, Scopus, and Web of Science. All observational studies evaluated the risk of CKD among PPI users, and non-users were considered for inclusion. Two reviewers conducted data extraction and assessed the risk of bias. Random-effect models were used to calculate pooled effect sizes. A total of 6,829,905 participants from 10 observational studies were included. Compared with non-PPI use, PPI use was significantly associated with an increased risk of CKD (RR 1.72, 95% CI: 1.02–2.87, p = 0.03). This updated meta-analysis showed that PPI was significantly associated with an increased risk of CKD. Association was observed in the same among moderate-quality studies. Until further randomized control trials (RCTs) and biological studies confirm these results, PPI therapy should not stop patients with gastroesophageal reflux disease (GERD). However, caution should be used when prescribing to patients with high-risk kidney disease.

19 June 2023 in Diagnostics
Verified
Journal Article
Open access
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CWChieh-Chen Wu
Chieh-Chen Wu
Chun-Hsien SuChun-Hsien Su
Chun-Hsien Su
Md. Mohaimenul IslamMd. Mohaimenul Islam
Md. Mohaimenul Islam
MLMao-Hung Liao
Mao-Hung Liao
The applications of artificial intelligence (AI) in dementia research have garnered significant attention, prompting the planning of various research endeavors in current and future studies. The objective of this study is to provide a comprehensive overview of the research landscape regarding AI and dementia within scholarly publications and to suggest further studies for this emerging research field. A search was conducted in the Web of Science database to collect all relevant and highly cited articles on AI-related dementia research published in English until 16 May 2023. Utilizing bibliometric indicators, a search strategy was developed to assess the eligibility of titles, utilizing abstracts and full texts as necessary. The Bibliometrix tool, a statistical package in R, was used to produce and visualize networks depicting the co-occurrence of authors, research institutions, countries, citations, and keywords. We obtained a total of 1094 relevant articles published between 1997 and 2023. The number of annual publications demonstrated an increasing trend over the past 27 years. Journal of Alzheimer’s Disease (39/1094, 3.56%), Frontiers in Aging Neuroscience (38/1094, 3.47%), and Scientific Reports (26/1094, 2.37%) were the most common journals for this domain. The United States (283/1094, 25.86%), China (222/1094, 20.29%), India (150/1094, 13.71%), and England (96/1094, 8.77%) were the most productive countries of origin. In terms of institutions, Boston University, Columbia University, and the University of Granada demonstrated the highest productivity. As for author contributions, Gorriz JM, Ramirez J, and Salas-Gonzalez D were the most active researchers. While the initial period saw a relatively low number of articles focusing on AI applications for dementia, there has been a noticeable upsurge in research within this domain in recent years (2018–2023). The present analysis sheds light on the key contributors in terms of researchers, institutions, countries, and trending topics that have propelled the advancement of AI in dementia research. These findings collectively underscore that the integration of AI with conventional treatment approaches enhances the effectiveness of dementia diagnosis, prediction, classification, and monitoring of treatment progress.

1 October 2022 in Healthcare
Verified
Journal Article
Open access
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TCTsung Chen
Tsung Chen
CWChyi-In Wu
Chyi-In Wu
MCMing-Hsin Phoebe Chiu
Ming-Hsin Phoebe Chiu
JHJia-Lien Hsu
Jia-Lien Hsu
MLMao-Hung Liao
Mao-Hung Liao
WSWei-Chih Su
Wei-Chih Su
Objective: To explore the factors associated with the different uses of report cards, physician rating websites, social media, and Google, including awareness, physician finding, and decision-making based on reviews from the patient/client perspective. Methods: We used computer-assisted telephone interviews to conduct a nationwide representative survey in Taiwan. Results: The urbanization level of the area, income, and long-term health conditions were not associated with the three kinds of usage of the websites studied. Seeking health information was an important factor in the three kinds of website use. The employment industry was associated with awareness, and education level was associated with physician seeking and actions based on reviews. Conclusions: Different factors influenced the three kinds of usage: awareness, actual use (i.e., finding an appropriate physician), and decision-making based on reviews. Seeking health information is of primary importance regardless of how the websites are used. Practical implications: Policy-makers should focus on educating individuals working outside the health care sector to increase awareness of these websites and to assist individuals with low levels of education in increasing their use of these websites.

7 May 2026 in Healthcare
Verified
Journal Article
Open access
PDF file
MLMao-Hung Liao
Mao-Hung Liao
YTYafang Tsai
Yafang Tsai
SWShih-Wang Wu
Shih-Wang Wu
CLChien-Ying Lee
Chien-Ying Lee
SSShwn-Huey Shieh
Shwn-Huey Shieh
Background: Interdisciplinary teamwork is widely recognized as a critical component of high-quality healthcare delivery. Healthcare services are delivered through interactions between healthcare professionals and patients; employees’ attitudes and behaviors may play a pivotal role in determining healthcare quality. Purpose: This study aimed to examine the effects of teamwork climate on employees’ job satisfaction and perceived healthcare quality. Methods: A cross-sectional survey design was employed to assess hospital employees’ perceptions of teamwork climate, job satisfaction, and healthcare quality. We adopted a structured questionnaire to collect data. A total of 528 questionnaires were distributed, and 462 valid responses were obtained, yielding a valid response rate of 87.5%. Data were analyzed using SPSS version 22.0. Descriptive statistics and one-way analysis of variance (ANOVA) were conducted to examine differences across demographic characteristics. Correlation analyses were performed to evaluate the relationships among teamwork climate, job satisfaction, and healthcare quality. Results: The findings indicated that teamwork climate was positively associated with perceived healthcare quality (r = 0.4333, p < 0.001) and job satisfaction (r = 0.695, p < 0.001). Conclusions: A positive teamwork climate is associated with higher levels of job satisfaction and improved perceptions of healthcare quality. These results suggest that hospital administrators should prioritize interventions that foster a supportive teamwork environment, as such efforts may enhance employees’ work attitudes and contribute to better healthcare quality.