Background: We compared corneal visualization Scheimpflug technology (CST) parameters between eyes with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Methods: A retrospective analysis was performed on data from 89 eyes with POAG and 83 eyes with PACG that had CST examinations. CST parameters were compared between eyes with POAG and those with PACG using a linear mixed model (LMM). Results: No differences were observed in age, central corneal thickness, intraocular pressure, or use of antiglaucoma eye drops between the two groups. Patients with PACG had a significantly shorter axial length (AL), a higher proportion of females, CST parameters, longer applanation 2 (A2) time, deeper A2 deformation amplitude, shorter peak distance, longer whole eye movement, and longer whole eye movement time than patients with POAG. The highest concavity (HC) length and PD showed a significant positive correlation with AL. However, A1 length, A1 deformation amplitude, A2 time, A2 velocity, A2 length, A2 deformation amplitude, HC time, whole eye movement, and whole eye movement time were negatively correlated with AL. Conclusions: The biomechanical properties of the cornea differed between POAG and PACG. In some parts, AL differences between the POAG and PACG groups might contribute to the variation in CST parameters.

This retrospective study evaluated differences in Corvis ST tonometry (CST) parameters between eyes with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) using propensity score matching. We analyzed 48 eyes with POAG and 48 eyes with PACG. Twelve CST parameters were compared using linear mixed-effects models, with group as a fixed effect and subject ID as a random intercept to account for inter-eye correlation, adjusting for age, sex, axial length, intraocular pressure, and central corneal thickness. Multiple comparisons were controlled using the Benjamini–Hochberg procedure. Compared with POAG eyes, PACG eyes showed longer A2 time, greater A2 deformation amplitude, and greater whole-eye movement; however, these differences were no longer statistically significant after correction for multiple testing. After adjustment for relevant covariates and correction for multiple comparisons, this study did not demonstrate statistically significant differences in CST parameters between POAG and PACG eyes. The uncorrected trends toward greater indentation-related responses in PACG eyes should be regarded as exploratory.

This study investigated the relationship between Corvis ST tonometry parameters and mean blur rate in the optic nerve head tissue area (MBR-T) in healthy eyes. Corneal biomechanical properties and MBR-T were measured in 100 eyes from 56 healthy participants in Japan using Corvis ST tonometry and laser speckle flowgraphy, respectively. Axial length, central corneal thickness, and intraocular pressure were also recorded. Linear mixed-effects models were applied to evaluate the associations between corneal biomechanical properties and MBR-T. Model selection was performed using the second-order bias-corrected Akaike Information Criterion (AICc). The optimal predictive model for MBR-T was as follows: MBR-T = 21.1607 (intercept) – 1.6317 × Sex (Male) – 4.8626 × A2 deformation amplitude – 5.7932 × HC deformation amplitude (AICc = 409.9). In healthy eyes, greater corneal deformability was associated with lower MBR-T.

Background: We compared corneal visualization Scheimpflug technology (CST) parameters between eyes with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Methods: A retrospective analysis was done on data from 89 eyes with POAG and 83 eyes with PACG that had CST examinations. CST parameters were compared between eyes with POAG and those with PACG using a linear mixed model (LMM). Results: No differences were observed in age, central corneal thickness, intraocular pressure, or use of antiglaucoma eye drops between the two groups. Patients with PACG had a significantly shorter axial length (AL), a higher proportion of females, CST parameters, longer applanation 2 (A2) time, deeper A2 deformation amplitude, shorter peak distance (PD), longer whole eye movement, and longer whole eye movement time than patients with POAG. Highest concavity (HC) length and PD showed a significant positive correlation with AL. However, A1 length, A1 deformation amplitude, A2 time, A2 velocity, A2 length, A2 deformation amplitude, HC time, whole eye movement, and whole eye movement time were negatively correlated with AL. Conclusions: Biomechanical properties of the cornea differed between PACG and POAG. In some parts, AL differences between the POAG and PACG groups might contribute to the variation in CST parameters.

To evaluate differences in Corvis ST tonometry (CST) parameters between healthy eyes and eyes with primary angle-closure glaucoma (PACG). We retrospectivel