Single-task construction robots (STCRs) have become a popular research topic for decades. However, there is still a gap in the ubiquitous application of STCRs for onsite construction due to various reasons, such as cost concerns. Therefore, cost–benefit analysis (CBA) can be used to measure the net economic benefit of the STCRs, compared to traditional construction methods, in order to boost the implementation of STCRs. This paper presents a simple and practical framework for the economic evaluation of STCRs and conducts a case study of a cable-driven facade installation robot to verify the method. The results show that the cable-driven robot for facade installation is worth investing in in the UK, as well as in the majority of G20 countries. Furthermore, other socioenvironmental implications of STCRs and the limitations of the study are also discussed. In conclusion, the proposed method is highly adaptable and reproducible. Therefore, researchers, engineers, investors, and policy makers can easily follow and customize this method to assess the economic advantages of any STCR systems, compared to traditional construction technologies.

The transition towards a Circular Economy (CE) in the construction sector is essential to achieving sustainable, inclusive smart cities. This study examines the integration of CE principles into construction policies across four key global contexts: the European Union (focusing on Italy and Germany), the United States, and Japan. Through a comparative policy analysis, the research identifies best practices, implementation barriers, and the role of digitalization in advancing CE strategies. In Europe, CE is embedded in policy frameworks such as the Green Deal and the New Circular Economy Action Plan, driving the shift toward sustainable urban development. The United States, while in the early stages of CE adoption, is fostering circular initiatives at local levels, particularly in waste management and building deconstruction. Japan’s policy landscape integrates CE within a broader strategy for resource efficiency, emphasizing technological innovation. The findings highlight the necessity of a research-driven approach to inform policies that leverage digital tools, such as Building Information Modeling and Digital Product Passports, to enhance material traceability and urban circularity. This study contributes to the global effort of designing smart cities that are not only technologically advanced but also environmentally and socially sustainable through the adoption of CE principles in the built environment.

(1) The overall energy requirement of a building may be impacted by the building design, the selection of materials, the construction methods, and lifecycle management. To achieve an optimum energy-efficiency level when dealing with a new building or renovation project, it is important to improve the entire construction process as it is not enough to merely focus on the operational phase. If conventional construction practices do not evolve, compromise, or adapt to necessary changes, then it becomes challenging to deliver an ultimate low energy building. (2) This paper demonstrates the trend of off-site prefabrication and its production principles and the notions of open-building design and Design for X, as well as offering an overview of the development of automation in construction, which provides both insights and evaluations based on the context of the research. (3) Three European Union Horizon 2020 research projects were evaluated, and the outcome of the projects served as the backbone for the research and inspired the design of the proposed integrated façade system. Two design scenarios were proposed to demonstrate the potential improvements that could be achieved in a new build as well as in renovation projects. (4) The research lays a foundation for establishing a larger cross-disciplinary collaboration in the future.

Background: A considerable proportion of people with schizophrenia spectrum disorders do not take antipsychotic medication but seem to be functioning well. However, little is known about this group. To test the assumption that absence of medication is compensated for by more effective coping and increased social support, this study compared symptoms, functioning, coping strategies and social support in non-medicated and medicated individuals with schizophrenia spectrum disorders.Method: In all, 48 participants with a DSM-IV schizophrenia spectrum disorder who were taking (n= 25) or not taking antipsychotic medication (n= 23) were included. Assessment consisted of self-ratings of symptoms, symptom-related distress and social support combined with a semi-structured interview that assessed general and social functioning, subjective evaluation of symptoms and coping strategies.Results: Symptom severity and distress did not differ between the groups. However, the non-medicated participants had significantly higher levels of general functioning than medicated participants and a longer duration of being non-medicated was significantly associated with a higher level of general functioning. In contrast to the hypotheses, not taking medication was not associated with more effective coping strategies or with higher levels of social support. Medicated participants more frequently reported the use of professional help as a coping strategy.Conclusions: Our results corroborate previous studies finding improved functioning in individuals with schizophrenia spectrum disorders who do not take medication compared with those who take medication, but do not support the notion that this difference is explicable by better coping or higher levels of social support. Alternative explanations and avenues for research are discussed.

Objectives: The noradrenergic innervation of lymphoid organs controls several immune cell functions and local blood perfusion. Considering that cell and antigen uptake depend on the blood supply to lymphoid organs, the hypothesis was tested that feedback signals from activated immune cells control sympathetic vasomotor activity. Methods: We determined the blood flow in spleen and mesenteric lymph nodes (mLN) of Wistar Kyoto rats during immune stimulation with endotoxin (LPS; 10 µg/kg) and following disruption of the noradrenergic transmission. Results: Our data indicate that (a) the splenic noradrenaline content, which reflects the density of the sympathetic innervation, is 5 times higher in the spleen than in other peripheral organs and the spleen receives stronger tonic sympathetic input than mLN; (b) immune stimulation with LPS causes a 4-fold increase in the IL-1β production in the spleen, but only 2-fold in mLN; (c) IL-1β causes an inhibition of the sympathetic vasoconstrictor tonus in the spleen, but has no significant effect on the noradrenergic vascular tonus in mLN, and (d) in mLN, the local hyperemia induced by LPS is attenuated by the degranulation of vesicular stores of histamine and serotonin, indicating that these monoamines participate in the vasodilator effect of LPS in mLN. Conclusions: The present experiments, taken together with our previous studies, indicate that the control of blood supply to the spleen and mLN involves different mechanisms. While blood perfusion in the spleen depends on the inhibition of the noradrenergic vasoconstriction by endogenously produced IL-1β, other vasoactive mediators such as serotonin and histamine play a role in the control of mLN perfusion.