Mario Lusini

Prof. Mario Lusini

orcid

Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 April 2021 in Sensors
Verified
Journal Article
Open access
PDF file
Alessandro ZompantiAlessandro Zompanti
Alessandro Zompanti
ASAnna Sabatini
Anna Sabatini
SGSimone Grasso
Simone Grasso
Giorgio PennazzaGiorgio Pennazza
Giorgio Pennazza
Giuseppe FerriGiuseppe Ferri
Giuseppe Ferri
Marco SantonicoMarco Santonico
Marco Santonico
The use of wearable sensors for health monitoring is rapidly growing. Over the past decade, wearable technology has gained much attention from the tech industry for commercial reasons and the interest of researchers and clinicians for reasons related to its potential benefit on patients’ health. Wearable devices use advanced and specialized sensors able to monitor not only activity parameters, such as heart rate or step count, but also physiological parameters, such as heart electrical activity or blood pressure. Electrocardiogram (ECG) monitoring is becoming one of the most attractive health-related features of modern smartwatches, and, because cardiovascular disease (CVD) is one of the leading causes of death globally, the use of a smartwatch to monitor patients could greatly impact the disease outcomes on health care systems. Commercial wearable devices are able to record just single-lead ECG using a couple of metallic contact dry electrodes. This kind of measurement can be used only for arrhythmia diagnosis. For the diagnosis of other cardiac disorders, additional ECG leads are required. In this study, we characterized an electronic interface to be used with multiple contactless capacitive electrodes in order to develop a wearable ECG device able to perform several lead measurements. We verified the ability of the electronic interface to amplify differential biopotentials and to reject common-mode signals produced by electromagnetic interference (EMI). We developed a portable device based on the studied electronic interface that represents a prototype system for further developments. We evaluated the performances of the developed device. The signal-to-noise ratio of the output signal is favorable, and all the features needed for a clinical evaluation (P waves, QRS complexes and T waves) are clearly readable.

17 November 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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AMAlessia Mattei
Alessia Mattei
ASAlessandro Strumia
Alessandro Strumia
MBMaria Benedetto
Maria Benedetto
Antonio NennaAntonio Nenna
Antonio Nenna
LSLorenzo Schiavoni
Lorenzo Schiavoni
MCMassimiliano Carassiti
Massimiliano Carassiti
Right ventricular (RV) dysfunction frequently occurs after cardiac surgery and is linked to adverse postoperative outcomes, including mortality, reintubation, stroke, and prolonged ICU stays. While various criteria using echocardiography and hemodynamic parameters have been proposed, a consensus remains elusive. Distinctive RV anatomical features include its thin wall, which presents a triangular shape in a lateral view and a crescent shape in a cross-sectional view. Principal causes of RV dysfunction after cardiac surgery encompass ischemic reperfusion injury, prolonged ischemic time, choice of cardioplegia and its administration, cardiopulmonary bypass weaning characteristics, and preoperative risk factors. Post-left ventricular assist device (LVAD) implantation RV dysfunction is common but often transient, with a favorable prognosis upon resolution. There is an ongoing debate regarding the benefits of concomitant surgical repair of the RV in the presence of regurgitation. According to the literature, the gold standard techniques for assessing RV function are cardiac magnetic resonance imaging and hemodynamic assessment using thermodilution. Echocardiography is widely favored for perioperative RV function evaluation due to its accessibility, reproducibility, non-invasiveness, and cost-effectiveness. Although other techniques exist for RV function assessment, they are less common in clinical practice. Clinical management strategies focus on early detection and include intravenous drugs (inotropes and vasodilators), inhalation drugs (pulmonary vasodilators), ventilator strategies, volume management, and mechanical support. Bridging research gaps in this field is crucial to improving clinical outcomes associated with RV dysfunction in the near future.

31 August 2007 in Clinical Therapeutics
Verified
Journal Article
Closed access
RCRaffaella Coccia
Raffaella Coccia
CSCristiano Spadaccio
Cristiano Spadaccio
CFCesira Foppoli
Cesira Foppoli
MPMarzia Perluigi
Marzia Perluigi
ECElvio Covino
Elvio Covino
MCMassimo Chello
Massimo Chello


11 October 2022 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
FNFrancesco Nappi
Francesco Nappi
OGOmar Giacinto
Omar Giacinto
MLMario Lusini
Mario Lusini
MGMaria Luisa Garo
Maria Luisa Garo
CCClaudio Caponio
Claudio Caponio
MCMassimo Chello
Massimo Chello
(1) Background: Bicuspid aortic valve (BAV) is the most frequent congenital cardiac disease. Alteration of ascending aorta diameter is a consequence of shear stress alterations due to haemodynamic abnormalities developed from inadequate valve cusp coaptation. (2) Objective: This narrative review aims to discuss anatomical, pathophysiological, genetical, ultrasound, and radiological aspects of BAV disease, focusing on BAV classification related to imaging patterns and flux models involved in the onset and developing vessel dilatation. (3) Methods: A comprehensive search strategy was implemented in PubMed from January to May 2022. English language articles were selected independently by two authors and screened according to the following criteria. (4) Key Contents and Findings: Ultrasound scan is the primary step in the diagnostic flowchart identifying structural and doppler patterns of the valve. Computed tomography determines aortic vessel dimensions according to the anatomo-pathology of the valve. Magnetic resonance identifies hemodynamic alterations. New classifications and surgical indications derive from these diagnostic features. Currently, indications correlate morphological results, dissection risk factors, and genetic alterations. Surgical options vary from aortic valve and aortic vessel substitution to aortic valve repair according to the morphology of the valve. In selected patients, transcatheter aortic valve replacement has an even more impact on the treatment choice. (5) Conclusions: Different imaging approaches are an essential part of BAV diagnosis. Morphological classifications influence the surgical outcome.

24 September 2022 in Current Infectious Disease Reports
Verified
Journal Article
Closed access
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EZEnrico Maria Zardi
Enrico Maria Zardi
MCMassimo Chello
Massimo Chello
DZDomenico Maria Zardi
Domenico Maria Zardi
RBRaffaele Barbato
Raffaele Barbato
OGOmar Giacinto
Omar Giacinto
MLMario Lusini
Mario Lusini