Over the past decade mind and body practices, such as yoga and meditation, have raised interest in different scientific fields; in particular, the physiological mechanisms underlying the beneficial effects observed in meditators have been investigated. Neuroimaging studies have studied the effects of meditation on brain structure and function and findings have helped clarify the biological underpinnings of the positive effects of meditation practice and the possible integration of this technique in standard therapy. The large amount of data collected thus far allows drawing some conclusions about the neural effects of meditation practice. In the present study we used activation likelihood estimation (ALE) analysis to make a coordinate-based meta-analysis of neuroimaging data on the effects of meditation on brain structure and function. Results indicate that meditation leads to activation in brain areas involved in processing self-relevant information, self-regulation, focused problem-solving, adaptive behavior, and interoception. Results also show that meditation practice induces functional and structural brain modifications in expert meditators, especially in areas involved in self-referential processes such as self-awareness and self-regulation. These results demonstrate that a biological substrate underlies the positive pervasive effect of meditation practice and suggest that meditation techniques could be adopted in clinical populations and to prevent disease.

The role of emotional landmarks in navigation has been scarcely studied. Previous findings showed that valence and arousal of landmarks increase landmark’s salience and improve performance in navigational memory tasks. However, no study has directly explored the interplay between valence and arousal of emotionally laden landmarks in embodied and not-embodied navigational tasks. At the aim, 115 college students have been subdivided in five groups according to the landmarks they were exposed (High Positive Landmarks HPL; Low Positive Landmarks LPL; High Negative Landmarks HNL; Low Negative Landmarks LNL and Neutral Landmarks NeuL). In the embodied tasks participants were asked to learn a path in a first-person perspective and to recall it after five minutes, whereas in the not-embodied tasks participants were asked to track the learned path on a silent map and to recognize landmarks among distractors. Results highlighted firstly the key role of valence in the embodied task related to the immediate learning, but not to the delayed recall of the path, probably because of the short retention interval used. Secondly, results showed the importance of the interplay between valence and arousal in the non-embodied tasks, specifically, neutral and high negative emotional landmarks yielded the lowest performance probably because of the avoidance learning effect. Implications for future research directions are discussed.

In the present study we analysed the bisecting behaviour of 287 chronic right brain-damaged patients by taking into account the presence and severity of extrapersonal and/or personal neglect diagnosed with the hemineglect battery. We also analysed right brain-damaged patients who had (or did not have) neglect according to their line bisection performance. Our results showed that performance of the line bisection task correlates with performance of cancellation tasks, reading and perceptual tasks, but not with the presence of personal neglect. Personal neglect seems to be unrelated to line bisection behaviour. Indeed, patients affected by extrapersonal and personal neglect do not show more severe neglect in line bisection than patients with only extrapersonal neglect. Furthermore, we observed that 20.56% of the patients were considered affected or not by neglect on the line bisection task compared with the other spatial tasks of the hemineglect battery. We conclude that using a battery with multiple tests is the only way to guarantee a reliable diagnosis and effectively plan for rehabilitative training.

Aging involves several changes depending on genetic and behavioral factors, such as lifestyle and the number and quality of social relationships, which in turn can be influenced by empathy. Here, the change in the perceived social support across the lifespan as a function of empathy was investigated, considering the mediating role of empathy after controlling for gender and education. In total, 441 people (18–91 years old) filled in the Italian short version of the Interpersonal Support Evaluation List (ISEL-12), the Social Support Questionnaire (SSQ6), as well as the Empathy Questionnaire (EQ), and the Reading the Mind in the Eyes test (RMET). The mediation analyses with ISEL-12 showed that age and the EQ fully mediated the relationship between age and appraisal, belonging, and tangible scores. Further, the EQ fully mediated only the relationship between age and SSQ6-People. These results showed that empathic skills are key in the relationships between age and social support. This suggests that empathy can trigger social support and, ultimately, well-being if stimulated across the lifespan, especially from a young age; this would help to form the socio-emotional competence across the years as a sort of cushion that can be useful in the older to fulfill active aging.

The ‘Reading the Mind in the Eyes’ test was developed by Baron-Cohen and his co-workers. This test provides them the unique opportunity to evaluate social cognition assessing the ability to recognize the mental state of others using only the expressions around the eyes. In healthy populations, however, it has produced conflicting results, particularly regarding sex differences and number of items to use. In this study we performed two studies: The first one investigated the presence of gender effects and the sensitivity of test stimuli; the second one considered other individual factors (i.e. artistic attitude, social empathy and personality traits) that could influence the ability to understand emotions from gaze. Our results demonstrated a sex effect, which can be more or less attenuated by the nature of the stimuli. This could be as aforementioned the result of the following, empathy or artistic attitude in being proficient in understanding the mental states of others.

Reliable and valid measures are necessary to assess subjective working memory complaints that can be distinct from objective memory performance. The Working Memory Questionnaire (WMQ) is a self-administered scale proposed by Vallat-Azouvi. It assesses the three different working memory domains (memory storage, attention, and executive functions) in accordance with Baddeley’s working memory model. Our aim was to propose an Italian translation of the WMQ and provide normative data. We collected normative data from 697 healthy Italian participants aged between 18 and 88 years. Percentiles and cutoff scores, taking into consideration age, gender, and education, were provided for the WMQ total scores and the three separate domains. The performance on the WMQ was influenced by age and education. In particular, age and education affected self-perceived working memory efficacy. Our data demonstrate a significant correlation between the WMQ and paper-and-pencil tests assessing working memory, attention, and executive functions. This study provides normative data that have been adjusted for relevant demographics and percentile grids in an Italian population. The results are in line with a previous French study that also supported the use of the WMQ as a valid prescreening instrument for working memory deficits in clinical practice.