The context-based convolutional neural network (CNN) is one of the most well-known CNNs to improve the performance of semantic segmentation. It has achieved remarkable success in various medical image segmentation tasks. However, extracting rich and useful context information from complex and changeable medical images is a challenge for medical image segmentation. In this study, a novel Multi-Receptive-Field CNN (MRFNet) is proposed to tackle this challenge. MRFNet offers the optimal receptive field for each subnet in the encoder-decoder module (EDM) and generates multi-receptive-field context information at the feature map level. Moreover, MRFNet fuses these multi-feature maps by the concatenation operation. MRFNet is evaluated on 3 public medical image data sets, including SISS, 3DIRCADb, and SPES. Experimental results show that MRFNet achieves the outstanding performance on all 3 data sets, and outperforms other segmentation methods on 3DIRCADb test set without pre-training the model.

Osteoarthritis (OA) is the most common disease of arthritis. Analgesics are widely used in the treat of arthritis, which may increase the risk of cardiovascular diseases by 20% to 50% overall.There are few studies on the side effects of OA medication, especially the risk prediction models on side effects of analgesics. In addition, most prediction models do not provide clinically useful interpretable rules to explain the reasoning process behind their predictions. In order to assist OA patients, we use the eXtreme Gradient Boosting (XGBoost) method to balance the accuracy and interpretability of the prediction model. In this study we used the XGBoost model as a classifier, which is a supervised machine learning method and can predict side effects of analgesics for OA patients and identify high-risk features (RFs) of cardiovascular diseases caused by analgesics. The Electronic Medical Records (EMRs), which were derived from public knee OA studies, were used to train the model. The performance of the XGBoost model is superior to four well-known machine learning algorithms and identifies the risk features from the biomedical literature. In addition the model can provide decision support for using analgesics in OA patients. Compared with other machine learning methods, we used XGBoost method to predict side effects of analgesics for OA patients from EMRs, and selected the individual informative RFs. The model has good predictability and interpretability, this is valuable for both medical researchers and patients.

Cotton aphids (Aphis gossypii Glover) pose a significant threat to cotton growth, exerting detrimental effects on both yield and quality. Conventional methods for pest and disease surveillance in agricultural settings suffer from a lack of real-time capability. The use of edge computing devices for real-time processing of cotton aphid-damaged leaves captured by field cameras holds significant practical research value for large-scale disease and pest control measures. The mainstream detection models are generally large in size, making it challenging to achieve real-time detection on edge computing devices with limited resources. In response to these challenges, we propose GVC-YOLO, a real-time detection method for cotton aphid-damaged leaves based on edge computing. Building upon YOLOv8n, lightweight GSConv and VoVGSCSP modules are employed to reconstruct the neck and backbone networks, thereby reducing model complexity while enhancing multiscale feature fusion. In the backbone network, we integrate the coordinate attention (CA) mechanism and the SimSPPF network to increase the model’s ability to extract features of cotton aphid-damaged leaves, balancing the accuracy loss of the model after becoming lightweight. The experimental results demonstrate that the size of the GVC-YOLO model is only 5.4 MB, a decrease of 14.3% compared with the baseline network, with a reduction of 16.7% in the number of parameters and 17.1% in floating-point operations (FLOPs). The mAP@0.5 and mAP@0.5:0.95 reach 97.9% and 90.3%, respectively. The GVC-YOLO model is optimized and accelerated by TensorRT and then deployed onto the embedded edge computing device Jetson Xavier NX for detecting cotton aphid damage video captured from the camera. Under FP16 quantization, the detection speed reaches 48 frames per second (FPS). In summary, the proposed GVC-YOLO model demonstrates good detection accuracy and speed, and its performance in detecting cotton aphid damage in edge computing scenarios meets practical application needs. This research provides a convenient and effective intelligent method for the large-scale detection and precise control of pests in cotton fields.