Scanning edentulous arches during complete denture fabrication is a crucial step; however, the quality of the resulting digital scan is still questionable. The purpose of this study is to systematically review studies (both clinical and in vitro) and determine whether intraoral scanners have clinically acceptable accuracy when recording completely edentulous arches for the fabrication of removable complete dentures. An electronic search in medical databases like PubMed, Scopus, and Web of Science (WOS), using a combination of relevant keywords, retrieved 334 articles. After full-text evaluation, twelve articles fulfilled the inclusion criteria for this review (eight clinical studies and four in vitro studies). A quality analysis of the included studies was carried out using the QUADAS-2 tool. The accuracy values varied between different intraoral scanners. Different regions of the edentulous arches showed differences in trueness and precision values in both in vitro and clinical studies. Peripheral borders, the inner seal, and poorly traceable structures like the soft palate showed maximum discrepancies. The accuracy of intraoral scanners in recording clear anatomic landmarks like hard tissues with attached mucosa was comparable to conventional edentulous arch impressions. However, higher discrepancies were recorded when digitizing mobile and poorly traceable structures. Intraoral scanners can be used to digitize denture-bearing areas, but the interpretation of the peripheral border and the soft palate should be carefully carried out.

Journal of Clinical and Diagnostic Research aims to publish findings of doctors at grass root level and post graduate students, so that all unique medical experiences are recorded in literature.

Epidermoid cyst of the neck or auricular area are relatively more common than that of the oral cavity. In most cases about 80% they remain asymptomatic. But in about 20% cases it becomes painful because of secondary infection seeking treatment. Here we present a case report of biopsy proved Epidermoid cyst with life threatening infection.

To validate the reproducibility and inter-observer variability of 4 different indices Pink Esthetic Score/White Esthetic Score (PES/WES), Peri-Implant and Crown Index (PICI), Implant Crown Aesthetic Index (ICAI), and Copenhagen Index Score (CIS) in assessing the esthetics at single anterior maxilla tooth-supported prosthesis fabricated of 3 materials. Eight observers, 2 from each dental specialty (Prosthodontics, Orthodontics, Periodontics, and Oral Surgery) evaluated 45 patient photographs, with 15 patients randomly assigned to 1 of 3 treatment groups: porcelain-fused-to-metal (PFM), monolithic zirconia, or lithium disilicate single tooth-supported prostheses. Standardized photographs of each prosthesis were assessed in comparison with the contralateral tooth using 4 esthetic indices: PES/WES, ICAI, CIS, and PICI. Inter-examiner reliability within each specialty group was analyzed using the Intraclass Correlation Coefficient (ICC). To evaluate the effects of the index type and dental specialty (as within-subject factors), treatment group (as a between-subject factor), and their interactions, an ANOVA-type test statistic (ATS) was applied. Among the evaluated indices, ICAI and CIS demonstrated the highest levels of interobserver agreement across all crown types, whereas PES/WES and PICI exhibited comparatively lower reliability. Post hoc test with Bonferroni correction revealed that ICAI consistently yielded significantly lower esthetic scores compared to all other indices across crown types. (P=.006), Inter-group comparisons based on PES/WES scores indicated that zirconia crowns achieved significantly higher esthetic ratings than both PFM (P<.001) and lithium disilicate crowns (P=.048). Intra-group comparisons showed that, for each specialty, scores assigned using PES/WES, PICI and CIS were significantly higher than those obtained with ICAI. Pattern differences among specialties varied depending on the esthetic index utilized, indicating a significant interaction effect between specialty and scoring system. The findings of this study highlight that the choice of index significantly influences the esthetic assessment outcomes, and that certain indices may be more appropriate for detecting subtle esthetic differences, depending on examiner's clinical experience.

Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder characterized by hypogammaglobulinemia and impaired antibody production, pre