Shaghayegh Shajari

Dr. Shaghayegh Shajari

Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois, USA
orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 November 2023 in Sensors
Verified
Journal Article
Open access
PDF file
Shaghayegh ShajariShaghayegh Shajari
Shaghayegh Shajari
KKKirankumar Kuruvinashetti
Kirankumar Kuruvinashetti
Amin KomeiliAmin Komeili
Amin Komeili
USUttandaraman Sundararaj
Uttandaraman Sundararaj
Disease diagnosis and monitoring using conventional healthcare services is typically expensive and has limited accuracy. Wearable health technology based on flexible electronics has gained tremendous attention in recent years for monitoring patient health owing to attractive features, such as lower medical costs, quick access to patient health data, ability to operate and transmit data in harsh environments, storage at room temperature, non-invasive implementation, mass scaling, etc. This technology provides an opportunity for disease pre-diagnosis and immediate therapy. Wearable sensors have opened a new area of personalized health monitoring by accurately measuring physical states and biochemical signals. Despite the progress to date in the development of wearable sensors, there are still several limitations in the accuracy of the data collected, precise disease diagnosis, and early treatment. This necessitates advances in applied materials and structures and using artificial intelligence (AI)-enabled wearable sensors to extract target signals for accurate clinical decision-making and efficient medical care. In this paper, we review two significant aspects of smart wearable sensors. First, we offer an overview of the most recent progress in improving wearable sensor performance for physical, chemical, and biosensors, focusing on materials, structural configurations, and transduction mechanisms. Next, we review the use of AI technology in combination with wearable technology for big data processing, self-learning, power-efficiency, real-time data acquisition and processing, and personalized health for an intelligent sensing platform. Finally, we present the challenges and future opportunities associated with smart wearable sensors.

3 December 2022 in Advanced Science
Verified
Journal Article
Open access
Shaghayegh ShajariShaghayegh Shajari
Shaghayegh Shajari
Razieh SalahandishRazieh Salahandish
Razieh Salahandish
AZAzam Zare
Azam Zare
MHMohsen Hassani
Mohsen Hassani
SMShirin Moossavi
Shirin Moossavi
ASAmir Sanati-Nezhad
Amir Sanati-Nezhad
Stress affects cognition, behavior, and physiology, leading to lasting physical and mental illness. The ability to detect and measure stress, however, is poor. Increased circulating cortisol during stress is mirrored by cortisol release from sweat glands, providing an opportunity to use it as an external biomarker for monitoring internal emotional state. Despite the attempts at using wearable sensors for monitoring sweat cortisol, there is a lack of reliable wearable sweat collection devices that preserve the concentration and integrity of sweat biomolecules corresponding to stress levels. Here, a flexible, self‐powered, evaporation‐free, bubble‐free, surfactant‐free, and scalable capillary microfluidic device, MicroSweat, is fabricated to reliably collect human sweat from different body locations. Cortisol levels are detected corresponding to severe stress ranging from 25 to 125 ng mL−1 averaged across multiple body regions and 100–1000 ng mL−1 from the axilla. A positive nonlinear correlation exists between cortisol concentration and stress levels quantified using the perceived stress scale (PSS). Moreover, owing to the sweat variation in response to environmental effects and physiological differences, the longitudinal and personalized profile of sweat cortisol is acquired, for the first time, for various body locations. The obtained sweat cortisol data is crucial for analyzing human stress in personalized and clinical healthcare sectors.

20 February 2014 in The Scientific World Journal
Verified
Journal Article
Open access
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Shaghayegh ShajariShaghayegh Shajari
Shaghayegh Shajari
MSMohammad Hossein Sadeghi
Mohammad Hossein Sadeghi
HHHamed Hassanpour
Hamed Hassanpour
Advancement in machining technology of curved surfaces for various engineering applications is increasing. Various methodologies and computer tools have been developed by the manufacturers to improve efficiency of freeform surface machining. Selection of the right sets of cutter path strategies and appropriate cutting conditions is extremely important in ensuring high productivity rate, meeting the better quality level, and lower cutting forces. In this paper, cutting force as a new decision criterion for the best selection of tool paths on convex surfaces is presented. Therefore, this work aims at studying and analyzing different finishing strategies to assess their influence on surface texture, cutting forces, and machining time. Design and analysis of experiments are performed by means of Taguchi technique and analysis of variance. In addition, the significant parameters affecting the cutting force in each strategy are introduced. Machining strategies employed include raster, 3D-offset, radial, and spiral. The cutting parameters were feed rate, cutting speed, and step over. The experiments were carried out on low curvature convex surfaces of stainless steel 1.4903. The conclusion is that radial strategy provokes the best surface texture and the lowest cutting forces and spiral strategy signifies the worst surface texture and the highest cutting forces.

15 January 2026 in Nature Sensors
Verified
Journal Article
Open access
PDF file
SCSoongwon Cho
Soongwon Cho
Shaghayegh ShajariShaghayegh Shajari
Shaghayegh Shajari
YXYirui Xiong
Yirui Xiong
Kenneth MadsenKenneth Madsen
Kenneth Madsen
ZLZengyao Lv
Zengyao Lv
John A. RogersJohn A. Rogers
John A. Rogers
Cortisol is a key regulator of stress and circadian physiology, yet current monitoring relies on invasive blood sampling or saliva assays that are prone to contamination and provide limited temporal resolution. Wearable sweat cortisol sensors are promising, but require electronic sensing systems and have limited capability for long-term, time-sequenced monitoring. Here we present a wearable paper-based microfluidic platform that integrates plasmonic-gold-nanoflower-based colorimetric assays to enable non-invasive tracking of cortisol in eccrine sweat. Sweat is induced by carbachol iontophoresis and directed through collection channels using either electronically timed sequential activation or paper-based delay valves with self-powered electrochromic indicators. In human studies, the system resolved circadian variations, acute stress responses to cold pressor challenges, and jet-lag-associated disruptions, with the results closely matching those from saliva and serum assays. This wearable lateral flow technology establishes sweat as a viable medium for real-time hormone monitoring and may enable personalized management of stress, sleep and circadian misalignment.

29 December 2023 in Polymers
Verified
Journal Article
Open access
PDF file
RMRoxana Moaref
Roxana Moaref
Shaghayegh ShajariShaghayegh Shajari
Shaghayegh Shajari
USUttandaraman Sundararaj
Uttandaraman Sundararaj
The use of plastics in automobiles is increasing dramatically due to their advantages of low weight and cost-effectiveness. Various products can be manufactured by recycling end-of-life vehicle (ELV) plastic waste, enhancing sustainability within this sector. This study presents the development of an electromagnetic interference (EMI) shield that can be used for protecting electronic devices in vehicles by recycling waste bumpers of ethylene propylene diene monomer (EPDM) rubber from ELVs. EPDM waste was added to a unique combination of 40/60: PP/CaCO3 master batch and conductive nanofiller of carbon nanotubes using an internal melt mixing process. This nanocomposite was highly conductive, with an electrical conductivity of 5.2×10−1S·cm−1 for 5 vol% CNT in a 30 wt% EPDM/70 wt% PP/CaCO3 master batch and showed a high EMI shielding effectiveness of 30.4 dB. An ultra-low percolation threshold was achieved for the nanocomposite at 0.25 vol% CNT. Waste material in the composite improved the yield strain by about 46% and strain at break by 54% in comparison with the same composition without waste. Low cost and light-weight fabricated composite from ELV waste shows high EMI SE for application in electronic vehicles and opens a new path to convert waste to wealth.

17 June 2026 in Nature Biomedical Engineering
Verified
Journal Article
Closed access
SCSoongwon Cho
Soongwon Cho
SSSeongeun Son
Seongeun Son
HZHaohui Zhang
Haohui Zhang
Kenneth MadsenKenneth Madsen
Kenneth Madsen
ZCZiyu Chen
Ziyu Chen
John A. RogersJohn A. Rogers
John A. Rogers