Background: Since periodontitis prevalence has increased globally and there is a bidirectional relationship between periodontitis and diabetes mellitus (DM), new methods of preventing and screening involving DM biomarkers could impact periodontitis management. We aimed to develop a fuzzy system to estimate the risk of periodontitis in patients with DM. Methods: Body mass index (BMI), glycemia (G), total cholesterol (C), and triglyceride (T) measurements were collected from 87 patients diagnosed with DM. Oral examinations were performed, and the number of the periodontal pockets (nrPPs) was determined. A fuzzy system was developed: BMI and G as inputs resulted in Periodontitis Risk 1 (PRisk1) output; C and T as inputs resulted in Periodontitis Risk 2 (PRisk2) output. From PRisk1 and PRisk2, the cumulative periodontitis risk (PCRisk) was assessed. Linguistic terms and linguistic grades (very small, small, medium, big, and very big) were assigned to the numerical variables by using 25 different membership functions. PCRisk and nrPP values were statistically processed. Results: In our developed fuzzy system, BMI, G, C, and T as input data resulted in periodontitis risk estimation. PCRisk was correlated with nrPP: when PCRisk increased by 1.881 units, nrPP increased by 1 unit. The fuzzy logic-based system effectively estimated periodontitis risk in type 2 diabetes patients, showing a significant correlation with the number of periodontal pockets. These findings highlight its potential for early diagnosis and improved interdisciplinary care.
The paper is a partial synthesis of the work that a team within the Faculty of Managerial and Technological Engineering has in the field of modeling and simulation of systems with Petri nets. The paper deals with three issues. The first part is Modeling and simulation of manufacturing systems with timed Petri nets. The first part presents the way in which the performances of some manufacturing systems are evaluated using timed Petri nets. The first example is a manufacturing system specific to the textile industry. The system has three production lines. In this case, the modeling with timed Petri nets allows the analysis of the operation of the flow lines and highlights the bottleneck. Another modeled manufacturing system is specific to a series production, more precisely it refers to the manufacture of gas cookers within a company from Oradea. The model with Petri nets also describes the supply sequences of the stocks of parts and subassemblies. The next modeled system is an automated manufacturing system for the packaging of detergents. The complexity of the Detergent Packing System and the high level of automation, require the use of efficient modeling and simulation methods to verify the validity of the solutions adopted. In this chapter is present the model of a robotic welding cell. The second part of the paper, the transition from timed Petri nets to hierarchical colored Petri nets, shows how Petri nets were developed for a robotic cell for metallographic analysis. The third part is dedicated to modeling with colored Petri nets timed with complex colors of the flexible manufacturing cell A007 within the Department of Industrial Engineering.
1 January 2021 in IOP Conference Series: Materials Science and Engineering
The assimilation process must take place in the shortest possible time and with the lowest costs. These desires are achievable through the most efficient procedures. The paper proposes a procedure for managing the assimilation process of a new product, based on the critical path method. The procedure is intended for a company producing plastic products. In the first phase there was a critical analysis of the existing procedure for assimilating a new product. In the following the study presents how the activities carried out for the assimilation of a new product were organized into a project. To implement this project it was used the Microsoft Project software. This is a tool that allows project management to use the critical path method. By applying this method, it can identify the critical activities within the project. In order to minimize the execution time of the project, the execution time of the critical activities must be reduced. The duration of an activity can be reduced by allocating additional resources. Using the Microsoft Project software in the analyzed case, provides to decision makers information that allows them to make decisions that will reduce the duration of the assimilation process of a new product.
Platelet‐rich plasma (PRP) is gaining popularity across various medical fields, including orthopedics, for its potential in tissue regeneration and wound healing. As intra‐articular treatments evolve, PRP has emerged as a promising option for managing knee osteoarthritis, meniscus, and ligament injuries. This review aims to provide an update on the current applications of PRP in treating knee osteoarthritis and its clinical implications in orthopedic and sports medicine. We reviewed 180 eligible studies, and our findings suggest that PRP injections significantly improve knee joint function compared to alternative treatments. The use of PRP across various medical fields has been growing in popularity recently. PRP is a biological product derived from the plasma portion of a patient’s own blood, containing a higher concentration of platelets than normal. Its potential for tissue regeneration and wound healing has drawn significant attention from orthopedic surgeons, especially as intra‐articular treatment options continue to evolve. The benefits of PRP in treating various osteoarticular conditions have sparked considerable interest within the orthopedic community, particularly for managing knee osteoarthritis, meniscus tears, and ligament injuries. This review aims to provide an updated overview of the current applications of PRP in the treatment of knee osteoarthritis and to offer clinical insights into its use in orthopedic and sports medicine practices. We reviewed 180 relevant titles and abstracts that met the inclusion criteria. Compared to other treatment options, PRP injections significantly enhance knee joint function.
The aim of this study was to evaluate the effect of multi-walled carbon nanotubes (CNTs) on various material properties of the polyamide 66 (PA66) nanocomposites. This is achieved first by investigating the effect of CNTs (0.1–5 wt.%) on the material properties of PA66 pellets, and second, on the injection-molded PA66/CNT nanocomposites. Thermal analysis revealed that CNTs do not have a significant effect on the melting behavior and melting temperature of PA66/CNT nanocomposites, but they increase the crystallization temperature of the nanocomposites. Rheological analysis showed that the melt shear viscosity of the PA66 increased with increasing CNT content particularly above 1 wt.%. Additionally, the PA66 nanocomposites exhibit shear-thinning behavior, and this effect is more significant at higher CNT contents. The FT-IR analysis revealed the absence of chemical bonds between PA66 and CNTs and, consequently, the uniform dispersion of CNTs in the PA66 matrix. Mechanical testing indicated that the inclusion of CNTs (0.1 to 5 wt.%) in PA66 matrix could not improve the tensile modulus to a great extent, while it decreased the ultimate tensile strength of PA66 nanocomposites under tension. On the other hand, CNTs positively influenced the mechanical behavior under bending (+15% increase at 5 wt.%). Among the nanocomposites, PA66 filled with 5 wt.% CNTs exhibited the optimal mechanical performance in terms of tensile strength (58 MPa), tensile modulus (2689 MPa), bending modulus (2072 MPa), and bending strength (104 MPa). The experimental results also showcase the significant improvement in the tensile and bending mechanical properties of the injection-molded PA66 nanocomposites after thermal annealing at −40 °C and 180 °C for one hour. This experimental study provides guidelines for the structure–property–processability of the PA66 nanocomposites, revealing the complex relationship between the CNTs and the enhancement of mechanical properties, while highlighting the potential of thermal annealing in improving the mechanical performance of PA66 nanocomposites. This will be further investigated to promote the use of PA66 nanocomposite in industrial applications.