In this study, a minimal setup for the ankle joint kinematics estimation is proposed relying only on proximal information of the lower-limb, i.e. thigh muscles activity and joint kinematics. To this purpose, myoelectric activity of Rectus Femoris (RF), Biceps Femoris (BF), and Vastus Medialis (VM) were recorded by surface electromyography (sEMG) from six healthy subjects during unconstrained walking task. For each subject, the angular kinematics of hip and ankle joints were synchronously recorded with sEMG signal for a total of 288 gait cycles. Two feature sets were extracted from sEMG signals, i.e. time domain (TD) and wavelet (WT) and compared to have a compromise between the reliability and computational capacity, they were used for feeding three regression models, i.e. Artificial Neural Networks, Random Forest, and Least Squares - Support Vector Machine (LS-SVM). BF together with LS-SVM provided the best ankle angle estimation in both TD and WT domains (RMSE < 5.6 deg). The inclusion of Hip joint trajectory significantly enhanced the regression performances of the model (RMSE < 4.5 deg). Results showed the feasibility of estimating the ankle trajectory using only proximal and limited information from the lower limb which would maximize a potential transfemoral amputee user’s comfortability while facing the challenge of having a small amount of information thus requiring robust data-driven models. These findings represent a significant step towards the development of a minimal setup useful for the control design of ankle active prosthetics and rehabilitative solutions.

Recent studies have highlighted the possibility of using surface electromyographic (EMG) signals to develop human–computer interfaces that are also able to recognize complex motor tasks involving the hand as the handwriting of digits. However, the automatic recognition of words from EMG information has not yet been studied. The aim of this study is to investigate the feasibility of using combined forearm and wrist EMG probes for solving the handwriting recognition problem of 30 words with consolidated machine-learning techniques and aggregating state-of-the-art features extracted in the time and frequency domains. Six healthy subjects, three females and three males aged between 25 and 40 years, were recruited for the study. Two tests in pattern recognition were conducted to assess the possibility of classifying fine hand movements through EMG signals. The first test was designed to assess the feasibility of using consolidated myoelectric control technology with shallow machine-learning methods in the field of handwriting detection. The second test was implemented to assess if specific feature extraction schemes can guarantee high performances with limited complexity of the processing pipeline. Among support vector machine, linear discriminant analysis, and K-nearest neighbours (KNN), the last one showed the best classification performances in the 30-word classification problem, with a mean accuracy of 95% and 85% when using all the features and a specific feature set known as TDAR, respectively. The obtained results confirmed the validity of using combined wrist and forearm EMG data for intelligent handwriting recognition through pattern recognition approaches in real scenarios.

Gait phase recognition systems based on surface electromyographic signals (EMGs) are crucial for developing advanced myoelectric control schemes that enhance the interaction between humans and lower limb assistive devices. However, machine learning models used in this context, such as Linear Discriminant Analysis (LDA) and Support Vector Machine (SVM), typically experience performance degradation when modeling the gait cycle with more than just stance and swing phases. This study introduces a generalized phasor-based feature extraction approach (PHASOR) that captures spatial myoelectric features to improve the performance of LDA and SVM in gait phase recognition. A publicly available dataset of 40 subjects was used to evaluate PHASOR against state-of-the-art feature sets in a five-phase gait recognition problem. Additionally, fully data-driven deep learning architectures, such as Rocket and Mini-Rocket, were included for comparison. The separability index (SI) and mean semi-principal axis (MSA) analyses showed mean SI and MSA metrics of 7.7 and 0.5, respectively, indicating the proposed approach’s ability to effectively decode gait phases through EMG activity. The SVM classifier demonstrated the highest accuracy of 82% using a five-fold leave-one-trial-out testing approach, outperforming Rocket and Mini-Rocket. This study confirms that in gait phase recognition based on EMG signals, novel and efficient muscle synergy information feature extraction schemes, such as PHASOR, can compete with deep learning approaches that require greater processing time for feature extraction and classification.

The volitional control of powered assistive devices is commonly performed by mapping the electromyographic (EMG) activity of the lower limb to joints’ angular kinematics, which are then used as the input for regulation. However, during walking, the ground reaction force (GRF) plays a central role in the modulation of the gait, providing dynamic stability and propulsion during the stance phase. Including this information within the control loop of prosthetic devices can improve the quality of the final output, providing more physiological walking dynamics that enhances the usability and patient comfort. In this work, we explored the feasibility of the estimation of the ground reaction force vertical component (VGRF) by using only the EMG activities of the thigh and shank muscles. We compared two deep learning models in three experiments that involved different muscular configurations. Overall, the outcomes show that the EMG signals could be leveraged to obtain a reliable estimation of the VGRF during walking, and the shank muscles alone represent a viable solution if a reduced recording setup is needed. On the other hand, the thigh muscles failed in providing performance enhancements, either when used alone or together with the shank muscles. The results outline the feasibility of including GRF information within an EMG-driven control scheme for prosthetic and assistive devices.

The early diagnosis of diabetic neuropathy (DN) is fundamental in order to enact timely therapeutic strategies for limiting disease progression. In this work, we explored the suitability of standing balance task for identifying the presence of DN. Further, we proposed two diagnosis pathways in order to succeed in distinguishing between different stages of the disease. We considered a cohort of non-neuropathic (NN), asymptomatic neuropathic (AN), and symptomatic neuropathic (SN) diabetic patients. From the center of pressure (COP), a series of features belonging to different description domains were extracted. In order to exploit the whole information retrievable from COP, a majority voting ensemble was applied to the output of classifiers trained separately on different COP components. The ensemble of kNN classifiers provided over 86% accuracy for the first diagnosis pathway, made by a 3-class classification task for distinguishing between NN, AN, and SN patients. The second pathway offered higher performances, with over 97% accuracy in identifying patients with symptomatic and asymptomatic neuropathy. Notably, in the last case, no asymptomatic patient went undetected. This work showed that properly leveraging all the information that can be mined from COP trajectory recorded during standing balance is effective for achieving reliable DN identification. This work is a step toward a clinical tool for neuropathy diagnosis, also in the early stages of the disease.

Surface electromyography (sEMG) and pressure-based force myography (pFMG) are two complementary modalities adopted in hand gesture recognition due to their ability to capture muscle electrical and mechanical activity, respectively. While sEMG carries rich neural information about the intended gestures and has long been established as the primary control signal in myoelectric interfaces, pFMG has recently emerged as a stable modality that is less sensitive to sweat and can indicate motion onset earlier than sEMG, making their fusion promising for robust pattern recognition. However, gesture classification systems based on these signals often suffer from performance degradation due to limb position changes, which affect signal characteristics. To address this, we introduce MyoPose, a novel and lightweight spatial synergy–based feature set for enhancing neuromechanical control. MyoPose works on effectively decoding colocated sEMG-pFMG information to improve hand gesture recognition under limb position variability while remaining computationally efficient for resource-constrained hardware. The proposed MyoPose feature combined with Linear Discriminant Analysis (LDA), achieved 87.7% accuracy in a nine-hand gesture recognition task, outperforming standard myoelectric feature sets and comparable to a state-of-the-art decision-level multimodal fusion parallel CNN. Notably, MyoPose maintained computational efficiency, achieving real-time feasibility with an estimated controller delay of 110.62 ms, well within the operational requirement of 100–125 ms, as well as ultra-light memory requirement of 0.011 KB. The novelty of this study lies in providing an effective feature set for multimodal driven hand gesture recognition, handling limb position variations with robust accuracy, and showing potential for real-time feasibility for human-machine interfaces without the need for deep learning.