This paper presents the reliability assessment of an IoT-based sensor node designed for detecting combustible gas leaks in residential environments. Building on a previously published design that integrates low-power micromachined (Micro-Electro-Mechanical Systems, MEMS) pellistors and electrochemical Volatile Organic Compounds (VOC) sensors, this study evaluates the node’s long-term robustness and stability under both realistic and accelerated operating conditions. The system employs a dual-sensor strategy in which the VOC sensor acts as a sentinel, activating the pellistor only when necessary, thereby optimizing power consumption and extending battery life. BLE and LoRa communication capabilities support flexible deployment and real-time data transmission. To ensure suitability for safety-critical applications, we conducted comprehensive reliability testing, including accelerated life tests and environmental stress testing in compliance with IEC 60068 standards. The results confirm the system’s ability to maintain consistent performance and data integrity under thermal, mechanical, and chemical stress, demonstrating its robustness for prolonged operation in demanding environments. Overall, this work underscores the importance of rigorous reliability validation for IoT-based safety devices and positions the proposed solution as a significant step toward enhancing residential gas safety, with potential applications in broader industrial monitoring scenarios.

Thromboembolism, a global leading cause of mortality, needs accurate risk assessment for effective prophylaxis and treatment. Current stratification methods fall short in predicting thrombotic events, emphasizing the need for a deeper understanding of clot properties. Fibrin clot permeability, a crucial parameter in hypercoagulable states, impacts clot structure and resistance to lysis. Current clot permeability measurement limitations propel the need for standardized methods. Prior findings underscore the importance of clot permeability in various thrombotic conditions but call for improvements and more precise, repeatable, and standardized methods. Addressing these challenges, our study presents an upgraded, portable, and cost-effective system for measuring blood clot permeability, which utilizes a pressure-based approach that adheres to Darcy’s law. By enhancing precision and sensitivity in discerning clot characteristics, this innovation provides a valuable tool for assessing thrombotic risk and associated pathological conditions. In this paper, the authors present a device that is able to automatically perform the permeability measurements on plasma or fibrinogen in vitro-induced clots on specific holders (filters). The proposed device has been tailored to distinguish clot permeability, with high precision and sensitivity, between healthy subjects and high cardiovascular-risk patients. The precise measure of clot permeability represents an excellent indicator of thrombotic risk, thus allowing the clinician, also on the basis of other anamnestic and laboratory data, to attribute a risk score to the subject. The proposed instrument was characterized by performing permeability measurements in plasma and purified fibrinogen clots derived from 17 Behcet patients and 15 sex- and age-matched controls. As expected, our results clearly indicate a significant difference in plasma clot permeability in Behcet patients with respect to controls (0.0533 ± 0.0199 d vs. 0.0976 ± 0.0160 d, p < 0.001). This difference was confirmed in the patient’s vs. control fibrin clots (0.0487 ± 0.0170 d vs. 0.1167 ± 0.0487 d, p < 0.001). In conclusion, our study demonstrates the feasibility, efficacy, portability, and cost-effectiveness of a novel device for measuring clot permeability, allowing healthcare providers to better stratify thrombotic risk and tailor interventions, thereby improving patient outcomes and reducing healthcare costs, which could significantly improve the management of thromboembolic diseases.