The nutritional status of the mother-to-be has a key impact on the proper development of the fetus. Although all nutrients are important for the developing baby, recent research indicates the importance of adequate choline intake during the periconceptional period, pregnancy, and lactation. Choline plays a key role in the biosynthesis of cell membranes, supporting liver function, neurotransmission, brain development, and DNA and histone methylation. Choline participates in the formation of a child’s nervous system, supports its cognitive development, and reduces the risk of neural tube defects. The human body is incapable of producing sufficient choline to meet its needs; therefore, it must be obtained from the diet. Current data indicate that most women in their reproductive years do not achieve the recommended daily intake of choline. The presented narrative review indicates the importance of educating mothers-to-be and thereby increasing their awareness of the effects of choline on maternal and child health, which can lead to a more aware and healthy pregnancy and proper child development.

Background: Psoriasis is a chronic inflammatory disease frequently associated with metabolic comorbidities, psychological distress, and reduced quality of life. Its multifactorial nature and frequent overlap with other conditions pose substantial challenges in clinical management. Purpose: This narrative review emphasizes the importance of a multidisciplinary approach to psoriasis care, integrating dietary counseling, physical activity promotion, psychological support, and sleep interventions. While multidisciplinary care models such as integrated clinics and coordinated care pathways have been proposed, to our knowledge, this is the first review to comprehensively synthesize evidence across these interrelated domains. Methodology: A comprehensive literature search was conducted using PubMed, Scopus, Cochrane, and Web of Science to identify studies addressing psoriasis in the context of lifestyle, nutrition, mental health, and interdisciplinary collaboration. Results: Lifestyle modifications, including weight management, anti-inflammatory dietary patterns, stress reduction strategies, regular physical activity, and sleep optimization, may significantly reduce disease severity and improve patient-reported outcomes. Mental health disorders and sleep disturbances are common among individuals with psoriasis and are increasingly recognized as important determinants of disease progression and treatment response. Conclusion: Psoriasis management should extend beyond pharmacotherapy to address modifiable lifestyle-related factors. Integrating care from dermatologists, dietitians, psychologists, and physiotherapists facilitates a more comprehensive and individualized approach. This model has the potential to improve not only clinical outcomes but also sleep quality, psychological well-being, and long-term self-management in patients with psoriasis.

Background/Objectives: Generalized anxiety disorder (GAD) is one of the most commonly diagnosed anxiety disorders in primary care. The global lifetime prevalence of GAD is estimated at 3.7%, ranging from 1.6% in low-income countries to 5.0% in high-income countries, underscoring its widespread impact. Given the frequent co-occurrence of GAD with obesity, this association has important clinical implications, particularly for screening, prevention, and treatment strategies. The aim of this review is to identify potential biological mechanisms linking obesity and GAD, summarize the current state of knowledge in this area, and highlight existing research gaps, as well as directions for future research. Methods: This narrative review is based on the literature published between 2015 and 2025 concerning the co-occurrence of GAD and obesity, with a focus on potential shared mechanisms including HPA axis dysregulation, chronic inflammation, oxidative stress, insulin resistance, gut–brain axis and microbiota dysbiosis, sleep disturbance, and maladaptive eating behaviors. Results/Conclusions: A growing body of evidence suggests an important, albeit still ambiguously defined, relationship between obesity and GAD. GAD and obesity may reinforce each other, leading to a mutually reinforcing relationship. Despite growing interest, high-quality prospective and interventional studies focusing specifically on GAD are lacking. A potentially effective therapeutic approach should be integrated and multidisciplinary, combining psychological, pharmacological, and lifestyle interventions. It may also be beneficial for clinicians to consider routine assessment of anxiety in patients with obesity and, conversely, to monitor metabolic risk in individuals with GAD. Such an approach, targeting both mental and metabolic domains, holds promise for improving outcomes.

Background/Objectives: Childhood obesity is a global health problem that affects at least 41 million children under the age of five. Increased BMI in children is associated with serious long-term health consequences, such as type 2 diabetes, cardiovascular disease, and psychological problems, including depression and low self-esteem. Although the etiology of obesity is complex, research suggests that the diet and lifestyle of pregnant women play a key role in shaping metabolic and epigenetic changes that can increase the risk of obesity in their children. Excessive gestational weight gain, unhealthy dietary patterns (including the Western diet), and pregnancy complications (such as gestational diabetes) are some of the modifiable factors that contribute to childhood obesity. The purpose of this narrative review is to summarize the most important and recent information on the impact of the diet and lifestyle of pregnant women on the risk of childhood obesity. Methods: This article is a narrative review that aims to summarize the available literature on the impact of pregnant women’s diet and lifestyle on the risk of obesity in their offspring, with a focus on metabolic and epigenetic mechanisms. Results/Conclusions: Current evidence suggests that a pregnant woman’s lifestyle and diet can significantly contribute to lowering the risk of obesity in their offspring. However, further high-quality research is needed to understand better the metabolic and epigenetic relationships concerning maternal factors that predispose offspring to obesity.

The role of soy isoflavones, which are an example of functional food, is increasingly emphasised in the context of multiple diseases, including those related to fertility. One of the most common causes of female infertility is polycystic ovary syndrome (PCOS), which, in addition to hormonal disorders, is usually accompanied by metabolic and systemic disorders. Soy isoflavones may be helpful in treating conditions such as insulin resistance, inflammation, cardiovascular disease, and intestinal dysbiosis. The current article is a narrative review aimed at summarizing the available scientific reports on the impact of soy isoflavones on endocrine and metabolic mechanisms in women with PCOS. Despite the limitations, current scientific evidence suggests that soy isoflavones can significantly contribute to lowering metabolic risk and affect hormonal balance in women with PCOS. Promising results have come from studies on PCOS and the gut microbiota, where a bidirectional relationship is suggested: the influence of the gut microbiota on the bioavailability of soy isoflavones and the modulation of microbiota composition by these compounds. However, further interventional studies involving humans are needed to better understand the endocrine and metabolic relationships regarding the role and importance of soy isoflavones in the pathomechanisms of the development and treatment of these disorders.

BACKGROUND:Hypertension is one of the main modifiable risk factors linked to cardiovascular disease and its prevalence is currently increasing in various age groups. This study aimed to evaluate blood pressure, demographic data, workload, and lifestyle factors in nurses employed in hospitals in the Subcarpathian region of southeastern Poland. MATERIAL AND METHODS:This cross-sectional observational study was conducted among 627 professionally active nurses. Certified devices were used for measurements: body mass analyzer (Tanita MC-980 PLUS MA), automated sphygmomanometer (Welch Allyn 4200B), stadiometer (Seca 213), and tape measure (Seca 201). The frequency of consumption of specific product groups was assessed using a survey method. Analysis using R software (version 4.3.1) employed logistic regression to examine variables affecting hypertension occurrence. RESULTS:The study found that elevated blood pressure is more prevalent among nurses than they self-report. Logistic regression analysis identified significant predictors for hypertension, including age (odds ratio; OR=1.061; OR=1.045), working more than 1 job (OR=1.579; OR=1.864), and body mass index (OR=1.152; OR=1.113). CONCLUSIONS:Regular monitoring of blood pressure is necessary for early detection and timely intervention of hypertension. Enhancing nurses’ awareness of their own health will encourage proactive preventive measures. Implementing comprehensive education programs focused on the latest advances in cardiovascular disease prevention is essential.