Changes in lipid metabolism occur during the development and progression non-alcoholic fatty liver disease (NAFLD). However, the fatty acid (FA) profile in red blood cells (RBC) from patients with liver fibrosis remains unexplored. Thus, the goal of this study was to evaluate the fatty acid profile in RBC, dietary lipid intake and insulin resistance indicators in patients with NAFLD, according to the degree of hepatic fibrosis. Using elastography, patients were classified with (n = 52) and without (n = 37) advanced liver fibrosis. The fatty acid profile in RBC was analyzed using gas chromatography and the lipid intake was evaluated through a 24-h dietary recall. Subjects with advanced liver fibrosis had higher levels of palmitic, stearic and oleic acid and total monounsaturated fatty acid (MUFA) and insulin (p < 0.05), and lower levels of elongase very long chain fatty acids protein-6 and the delta-5-desaturase enzymatic activity (p < 0.05). These results suggest a lack of regulation of enzymes related to FA metabolism in patients with advanced fibrosis.

Food Consumption According to the Days of the Week – National Food Survey, 2008-2009

The study aimed to describe the use of table sugar and artificial sweeteners (AS) in Brazil. A representative sample (n = 32,749) of individuals aged > 10 years was examined from the Brazilian National Dietary Survey (2008–2009). Participants reported whether they use table sugar, AS, both, or none as sweeteners for their foods and beverages. Energy intake and the contribution of selected food groups to energy intake were evaluated according to the type of sweetener reported. Sample weights and design effects were considered in the analysis. The majority of the population (85.7%) used sugar to sweeten foods and beverages, 7.6% used AS, and 5.1% utilized both products. The use of AS was more frequent among the elderly (20%), women (10% versus 5.5%), overweight individuals (10% versus 6%), those who live in urban areas (8.5% versus 3%), and those who belong to the highest income quartile (14% versus 1.6%), compared with men, normal weight individuals, those who live in rural areas, and those who belong to the first income quartile, respectively. Overall, the mean daily energy intake of individuals using only sugar was approximately 16% higher than those who used AS exclusively. The contribution of staple foods to daily energy intake was higher in individuals who used sugar than those who used AS.

Objective To describe meal consumption habits and assess their associations with anthropometric indicators. Methods A cross-sectional study was performed on 1,749 elementary and high school students from public and private schools in the city of Rio de Janeiro, Brazil (mean age=15.3 years), who were selected for the baseline of the Longitudinal Study for Nutritional Assessment of Adolescents. Meal habits and meals consumed in the company of parents were assessed using a self-administered questionnaire. The consumption of the main meals was categorized as regular (daily) or irregular (≤6 times a week). The meal consumption profile was considered either satisfactory (breakfast, lunch, and dinner consumed on a daily basis) or unsatisfactory. Body Mass Index, waist-to-height ratio, and body fat percentage were calculated. The association between meal consumption habits and anthropometric indicators was estimated using multivariate logistic regression models, adjusted for age and sex and stratified according to the type of school. Results Regular lunch consumption was more frequent among private schools students, who also had higher frequency of eating dinner irregularly. Among students from private schools, the unsatisfactory meal consumption profile and irregular meal habits were associated with being overweight, having a high waist-to-height ratio, and increased body fat percentage. Among students from public schools, it was observed association between being overweight with irregular breakfast habits. Conclusion In adolescents, the association between meal habits and weight status may be modulated by socioeconomic condition.