Eleonora Zirone

Dr. Eleonora Zirone

orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 July 2020 in Science Advances
Verified
Journal Article
Open access
PDF file
LZLaura Zapparoli
Laura Zapparoli
SSS. Seghezzi
S. Seghezzi
EZEleonora Zirone
Eleonora Zirone
Giacomo GuidaliGiacomo Guidali
Giacomo Guidali
MTM. Tettamanti
M. Tettamanti
EPE. Paulesu
E. Paulesu
The feeling that physical events are caused by us is tied to our action planning rather than being a mere post hoc deduction.

30 July 2023 in Journal of Neurology
Verified
Journal Article
Open access
PDF file
FMFrancesca Mameli
Francesca Mameli
EZEleonora Zirone
Eleonora Zirone
RGRoberta Girlando
Roberta Girlando
ESElena Scagliotti
Elena Scagliotti
GRGiulia Rigamonti
Giulia Rigamonti
FRFabiana Ruggiero
Fabiana Ruggiero
Deep brain stimulation (DBS) is a well-established treatment that significantly improves the motor symptoms of patients with Parkinson’s disease (PD); however, patients may experience post-operative psychological distress and social maladjustments. This phenomenon has been shown to be related to patients’ pre-operative cognitive representations, such as expectations. In this systematic review, we discuss the findings on the role of the expectations of patients with PD regarding the clinical outcomes of DBS to identify areas of intervention to improve pre-operative patient education and promote successful post-operative psychosocial adjustment. PubMed was searched for relevant articles published up to 16 January 2023. Of the 84 identified records, 10 articles focusing on the treatment expectations of patients with PD undergoing DBS were included in this review. The selected studies were conducted among cohorts of patients with different DBS targets, among which the most common was the bilateral subthalamic nucleus. Overall, the data showed that patients’ expectations contribute to treatment efficacy. Experiments investigating the placebo effect itself have shown clinical improvement after the induction of positive therapeutic expectations; conversely, unrealistic treatment expectations can affect patient satisfaction after surgery, clinical outcomes, and subjective well-being. This review highlights the need for routine clinical practice to better investigate and manage patients' pre-operative expectations, as well as multidisciplinary education to improve patient satisfaction and psychosocial adjustment after DBS.

27 June 2023 in Neurological Sciences
Verified
Journal Article
Open access
PDF file
FRFabiana Ruggiero
Fabiana Ruggiero
EZEleonora Zirone
Eleonora Zirone
MMMaria Takeko Molisso
Maria Takeko Molisso
TCTiziana Carandini
Tiziana Carandini
GFGiorgio Fumagalli
Giorgio Fumagalli
FMFrancesca Mameli
Francesca Mameli
Objective: This study aimed to evaluate the experience with telemedicine in patients with cognitive impairments and their caregivers. Methods: We conducted a survey-based study of patients who completed neurological consultation via video link between January and April 2022. Results: A total of 62 eligible neurological video consultations were conducted for the following categories of patients: Alzheimer’s disease (33.87%), amnesic mild cognitive impairment (24.19%), frontotemporal dementia (17.74%), Lewy body dementia (4.84%), mixed dementia (3.23%), subjective memory disorders (12.90%), non-amnesic mild cognitive impairment (1.61%), and multiple system atrophy (1.61%). The survey was successfully completed by 87.10% of the caregivers and directly by the patients in 12.90% of cases. Our data showed positive feedback regarding the telemedicine experience; both caregivers and patients reported that they found neurological video consultation useful (caregivers: 87.04%, ‘very useful’; patients: 87.50%, ‘very useful’) and were satisfied overall (caregivers: 90.74%, ‘very satisfied’; patients: 100%, ‘very satisfied’). Finally, all caregivers (100%) agreed that neurological video consultation was a useful tool to reduce their burden (Visual Analogue Scale mean ± SD: 8.56 ± 0.69). Conclusions: Telemedicine is well received by patients and their caregivers. However, successful delivery incorporates support from staff and care partners to navigate technologies. The exclusion of older adults with cognitive impairment in developing telemedicine systems may further exacerbate access to care in this population. Adapting technologies to the needs of patients and their caregivers is critical for the advancement of accessible dementia care through telemedicine.

1 April 2020 in Archives of Physical Medicine and Rehabilitation
Verified
Journal Article
Closed access
FNFrancesco Negrini
Francesco Negrini
MPMatteo Preti
Matteo Preti
EZEleonora Zirone
Eleonora Zirone
DMDaniele Mazziotti
Daniele Mazziotti
MBMarco Biffi
Marco Biffi
LZLaura Zapparoli
Laura Zapparoli

22 July 2022 in Frontiers in Psychology
Verified
Journal Article
Open access
FMFrancesca Mameli
Francesca Mameli
EZEleonora Zirone
Eleonora Zirone
BCBenedetta Capetti
Benedetta Capetti
DMDenise Mellace
Denise Mellace
Roberta FerrucciRoberta Ferrucci
Roberta Ferrucci
FRFabiana Ruggiero
Fabiana Ruggiero
This review discussed the effects of the impact of the Coronavirus Disease 2019 (COVID-19) pandemic on the psychological wellbeing of people with Parkinson's disease (PD) focusing specifically on depressive symptoms, anxiety levels, sleep, and quality of life (QoL). Together with motor symptoms, psychological symptoms are common and disabling conditions in the clinical course of PD becoming a relevant topic as a result of the lockdown measure due to alter their everyday life. We searched on PubMed online electronic databases for English articles published between January 2020 and 31 December 2021. Twenty-eight relevant studies were found and included in the review. Heterogeneous data emerged from the topics analyzed. Overall, data from depression studies showed significant depressive symptoms if the patient was analyzed longitudinally or vs. a control group consisting in healthy subjects, while these differences become minimal when the control group is a family member. Differently, in most of the studies reviewed there is no evidence of a statistically significant impact on anxiety disorders, nor on the quality of sleep. Conversely, PD patients showed a statistically significant negative impact of QoL compared with control groups or other neurological conditions. Although these findings must be interpreted carefully in the light of the studies' limitations, both in methodology and design, collectively our review showed that COVID-19 pandemic has had negative effects on the mental health of people with PD, due to disruption of healthcare services, loss of usual activities and supports and reduction in physical activity.

28 March 2023 in Journal of Neural Transmission
Verified
Journal Article
Closed access
PDF file
EAEdoardo Nicolò Aiello
Edoardo Nicolò Aiello
ADAlfonsina D'Iorio
Alfonsina D'Iorio
FSFederica Solca
Federica Solca
STSilvia Torre
Silvia Torre
RBRuggero Bonetti
Ruggero Bonetti
BPBarbara Poletti
Barbara Poletti