Background and Aim: Coronavirus disease (COVID-19) has been announced as a life-threatening, highly transmissible infectious novel emerging disease worldwide. Rapid detection and epidemiological information are desperately needed to overcome the existing pandemic situation and alleviate national and international crises. Still, to date, there is no significant epidemiological study of COVID-19 available in Bangladesh, especially in the Chattogram division. However, the current study focuses on molecular detection, prevalence, and risk factors associated with COVID-19 in Southern Bangladesh. Materials and Methods: Standard diagnostic protocols through real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) were performed for molecular confirmation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Different patient demographics were analyzed for exploring the relationship of four factors – region, sex, age, and symptoms with the accumulated number of COVID-19 cases in the Southern Bangladesh during the period of May 13, 2020, to June 12, 2020. Results: A total of 2954 samples were tested where the cumulative prevalence of circulating SARS-CoV-2 was 29.76% (n=879; 95% CI: 28.11-31.44) in the selected study region. Among the risk factors, the present study revealed that flatland people (35.62%, 95% CI 33.61-37.67, OR=3.13) were more vulnerable to getting infected by SARS-CoV-2 than the people living in hill tracts (13.04%, 95% CI 10.73-15.63). People older than 50 years (34.68%, 95% CI 30.38-39.18) were designated the highest risk than other different age groups. A higher number of COVID-19 cases were confirmed in patients (36.0%, 95% CI 33.77-38.29, OR=1.76) with typical symptoms, but interestingly a significant number of asymptomatic carriers (20.39%, 95% CI 18.13-22.80) also positive for SARS-CoV-2. Conclusion: To the best of our knowledge, this is the first epidemiological report in the Southern Bangladesh for COVID- 19. The study's findings will contribute to health professionals and the policy-makers to take preventive measures against the next outbreak emergency for Bangladesh.

The global threat of antimicrobial resistance (AMR) to public health, especially in the animal ecosystems, is alarming. This review focuses on how antimicrobial use in aquaculture and livestock contributes to the emergence and spread of AMR on the basis of a One Health (OH) approach. Aquaculture and livestock are essential for meeting the global food demand. However, the use of antimicrobials to manage diseases and promote growth has contributed to the menace of AMR in human and environmental health. We suggest that an integrated approach to AMR management could be achieved by applying OH, which recognizes the common existence and interconnectivity between human, animal, and environmental health. It highlights sustainable actions, international guidelines, and even cross‐sectoral collaboration. These are demonstrated through case studies of existing solutions from various regions, offering models that can be adapted globally. The review concludes with recommendations regarding the stewardship of antimicrobials, regulatory changes, and surveillance improvements to address the growing global threat that AMR poses.

COVID-19 causes mild to severe respiratory illness in humans. Government and non-government authorities along with telecommunication, print and electronic media undertook extensive advertising campaign regarding protective measures against COVID-19 to raise the public awareness. Therefore, this web-based cross-sectional study was conducted to evaluate peoples' responses towards COVID-19 during the first wave of COVID-19 in Bangladesh. We performed univariate and multivariate analyses to estimate the association between demographic characteristics, awareness, and individual preventive measures. The overall awareness level of the majority of the respondents (89%, n=920) was good, but the overall score for individual-level preventive measures during lockdown was poor to moderate. The relation between a good level of awareness and a higher level of educational status was found statistically significant (aOR 5.87, 95% CI: 1.58-21.86). Service holders were two times more likely to follow COVID-19 prevention practices than students (aOR 2.08, 95% CI: 1.24-3.51). Despite having adequate knowledge on awareness, many respondents were reluctant to follow preventive measures during the lockdown. The outcomes of this study highlight the requirement for stringent execution of preventative measures by law enforcement agencies to stop the transmission of the COVID-19 virus.