Background: Emerging evidence suggests shared neurobiological mechanisms between epilepsy and autism spectrum disorder (ASD), including alterations in GABAergic signaling, synaptic plasticity, and functional connectivity. However, the prevalence of autistic traits and cognitive flexibility impairments in adolescents with epilepsy without ASD remains underexplored. Methods: This cross-sectional study compared 47 adolescents with epilepsy (12–18 years), 40 siblings, and 43 healthy controls. Participants were assessed using the Autism Spectrum Quotient–Adolescent Version (AQ-Adolescent) and the Cognitive Flexibility Scale (CFS). Clinical and developmental data were collected via standardized forms. Group differences were analyzed using ANOVA and Kruskal-Wallis tests, with post-hoc corrections. Correlations and logistic regression models examined associations between epileptic features, autistic traits, and cognitive flexibility. Results: The epilepsy group exhibited significantly higher autistic traits (mean AQ = 31.2) compared to siblings (26.3) and controls (19.8; p < 0.001), with focal seizures linked to a 7.5-fold increased risk of clinically significant traits (AQ ≥ 30; p = 0.040). Cognitive flexibility was markedly lower in the epilepsy group (mean CFS = 48.2) versus siblings (56.5) and controls (58.2; p < 0.001). A strong negative correlation emerged between AQ and CFS scores ( r = − 0.430, p < 0.001). Siblings of individuals with epilepsy had a 25-fold higher likelihood of elevated autistic traits ( p = 0.012), supporting familial endophenotypes. Conclusions: Adolescents with epilepsy demonstrate elevated autistic traits and cognitive inflexibility, independent of ASD diagnosis. The sibling findings suggest shared genetic or environmental risk factors. Early screening for these traits may guide targeted interventions to improve psychosocial outcomes.

HSV 1 encephalitis is the most common cause of sporadic and focal viral encephalitis. Opercular syndrome is characterized by swallowing and speech difficulties which are associated with deterioration of voluntary control of face, pharynx, tongue and chewing muscles. It can be developed in patients with Herpes simplex encephalitis (HSE). Here, a twelve-year-old boy who was diagnosed with HSE and Opercular syndrome, is presented. The patient recovered without sequela as a result of 30 days of intravenous and 10 days of oral acyclovir treatment. It might be important as well, to personalize and elongate the treatment in terms of prognosis.

Akademisyen Yayınevi yöneticileri, yaklaşık 30 yıllık yayın tecrübesini, kendi tüzel kişiliklerine aktararak uzun zamandan beri, ticarî faaliyetlerini sürdürmektedir. Anılan süre içinde, başta sağlık ve sosyal bilimler, kültürel ve sanatsal konular dahil 1000 kitabı yayımlamanın gururu içindedir. Uluslararası yayınevi olmanın alt yapısını tamamlayan Akademisyen, Türkçe ve yabancı dillerde yayın yapmanın yanında, küresel bir marka yaratmanın peşindedir. Bilimsel ve düşünsel çalışmaların kalıcı belgeleri sayılan kitaplar, bilgi kayıt ortamı olarak yüzlerce yılın tanıklarıdır. Matbaanın icadıyla varoluşunu sağlam temellere oturtan kitabın geleceği, her ne kadar yeni buluşların yörüngesine taşınmış olsa da, daha uzun süre hayatımızda yer edineceği muhakkaktır. Ağlayan Çocuk ve Ailesi Kübra İRDAY DEMİR Mehmet Cenk BELİBAĞLI Akut Nöromusküler Güçsüzlüğe Yaklaşım Arzu YILMAZ Özlem YAYICI KÖKEN Aşı Karşıtlığı Tarihçesi Önder KILIÇASLAN Corpus Callozum Agenezisi Arzu YILMAZ Özlem YAYICI KÖKEN Çocuk Acil Servisinde Status Epileptikusa Yaklaşım Tuğçe NALBANT Çocuklarda Kuduz Hastalığı ve Aşılamada Son Gelişmeler Gökce CELEP Çocuklarda Vulvovajinal Hastalıkların Değerlendirilmesi Dilek ORBATU Demet ALAYGUT Çocukluk Çağı Akut Lenfoblastik Lösemisi, Tedavisi ve Tedaviye Bağlı Erken Dönemde Görülen Yan Etkiler Meriç KAYMAK CİHAN Febril Nöbeti Olan Çocuğa Yaklaşım Emine TEKİN Obez Çocuk Muayenesinde Özellikli Bulgular Mehmet Cenk BELİBAĞLI Kübra İRDAY DEMİR PFAPA Sendromu Zafer BAĞCI Sakrokoksigeal Teratomlar Meriç KAYMAK CİHAN