Dr. Zulema Vargas-Osorio
FunGlass – Centre for Functional and Surface Functionalized Glass, Alexander Dubček University of Trenčín, Trenčín, Slovakia
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Academic Career Length
13Years (2014-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications20 August 2015 in European Journal of Inorganic Chemistry
Journal Article
YPYolanda Piñeiro
Yolanda PiñeiroZulema Vargas-Osorio
José RivasMLManuel Arturo López‐Quintela
Manuel Arturo López‐Quintela1 October 2019 in Food Chemistry
Journal Article
JGJesús M. González-Jartín
Jesús M. González-JartínLALisandra Alves
Lisandra AlvesAAAmparo Alfonso
Amparo AlfonsoYPYolanda Piñeiro
Yolanda PiñeiroSVSusana Yáñez Vilar
Susana Yáñez Vilar
Luis M. Botana +5
8 June 2022 in Biomedical Materials
Journal Article
Zulema Vargas-OsorioFRFlorian Ruther
Florian RutherSCSi Chen
Si Chen
SSSusanta Sengupta
Susanta Sengupta
Liliana Liverani
Aldo R. Boccaccini +2
Electrospun fibers based on biodegradable polyanionic or polycationic biopolymers are highly beneficial for biomedical applications. In this work, electrospun nanofibers made from poly(epsilon caprolactone) (PCL), chitosan (CS) and κ-carrageenan (κ-C) were successfully fabricated using several mixtures of benign solvents containing formic acid and acetic acid. The addition of κ-C improved the preparation procedure for the production of PCL/CS fibers by electrospinning. Moreover, a polymer mixture was selected to be stored at −20 °C for one month with the purpose to study the properties of the resulting fiber mat. The results indicated that fiber characteristics were not seriously compromised compared to the ones of those fabricated with the original solution, which represents an important reduction in produced waste. Thus, the interactions that occur between positively and negatively charged hydrophilic polysaccharides might induce higher stability to the linear aliphatic polyester in the polymer mixture. All fiber mats were morphologically, physico-chemically and mechanically characterized, showing average fiber diameters in the nano scale. A direct cell viability assay using ST-2 cells demonstrated cell proliferation after seven days of incubation for all prepared fiber mats, confirming their suitability as potential candidates for bone tissue engineering and wound healing applications.
9 November 2017 in Journal of Materials Chemistry B
Journal Article
Zulema Vargas-OsorioMGM. A. González-Gómez
M. A. González-Gómez
YPYolanda Piñeiro
Yolanda PiñeiroCVCarlos Vazquez-Vazquez
Carlos Vazquez-VazquezCRCarlos Rodríguez-Abreu
Carlos Rodríguez-AbreuJosé Rivas +1
In this paper, novel magnetic silica nanocomposites were prepared by anchoring magnetite nanoparticles onto the outer surface of mesoporous SBA-15 silica; the magnetic nanoparticles were prepared by microemulsion and solvothermal methods, varying the synthesis conditions in order to control the final physicochemical, textural and magnetic properties. The morphology and mesostructure of the materials were characterized by X-ray diffraction (XRD), Fourier-Transform Infrared Spectroscopy (FTIR), N2 adsorption–desorption, and Transmission and Scanning Electron Microscopy (TEM and SEM). Magnetic silica nanocomposites feature a two-dimensional hexagonal arrangement constituted by a homogeneous pore channel system with diameters between 13 and 18 nm and a Brunauer–Emmett–Teller (BET) surface area higher than 260 m2 g−1. The different morphologies of the samples are given by the presence of diverse magnetic nanoparticle arrangements covalently linked onto the outer surface of the mesoporous silica rods. This confers on them a superparamagnetic behaviour with a magnetic response between 50–80 emu g−1, even though the weight percent of magnetite present in the samples does not exceed 21.7%. In addition, the magnetic nanocomposites exhibit magnetic hyperthermia with moderate Specific Absorption Rate (SAR) values.
1 October 2020 in Chemosphere
Journal Article
JGJesús M. González-Jartín
Jesús M. González-JartínLALisandra Alves
Lisandra AlvesAAAmparo Alfonso
Amparo AlfonsoYPYolanda Piñeiro
Yolanda PiñeiroSVSusana Yáñez Vilar
Susana Yáñez VilarLuis M. Botana +6
11 April 2017 in Journal of Nanobiotechnology
Journal Article
ASAndres da Silva-Candal
Andres da Silva-CandalBABárbara Argibay
Bárbara ArgibayRIRamón Iglesias-Rey
Ramón Iglesias-ReyZulema Vargas-OsorioAVAlba Vieites-Prado
Alba Vieites-PradoJCJosé Castillo
José Castillo +8
Neurological diseases of diverse aetiologies have significant effects on the quality of life of patients. The limited self-repairing capacity of the brain is considered to be the origin of the irreversible and progressive nature of many neurological diseases. Therefore, neuroprotection is an important goal shared by many clinical neurologists and neuroscientists. In this review, we discuss the main obstacles that have prevented the implementation of experimental neuroprotective strategies in humans and propose alternative avenues for the use of neuroprotection as a feasible therapeutic approach. Special attention is devoted to nanotechnology, which is a new approach for developing highly specific and localized biomedical solutions for the study of the multiple mechanisms involved in stroke. Nanotechnology is contributing to personalized neuroprotection by allowing us to identify mechanisms, determine optimal therapeutic windows, and protect patients from brain damage. In summary, multiple aspects of these new players in biomedicine should be considered in future in vivo and in vitro studies with the aim of improving their applicability to clinical studies.
About Me
Dr. Zulema Vargas-Osorio is a Senior Researcher at FunGlass Centre, Alexander Dubček University of Trenčín, Slovakia. She received her PhD in Materials Science and Engineering from the National Autonomous University of Mexico (UNAM) in 2016, graduating with Summa Cum Laude Honors. In recognition of her outstanding academic achievements, she was awarded the prestigious Alfonso Caso Medal and the Third Youth Prize of Mexico City. With over 18 years of research experience, Dr. Vargas-Osorio specializes in the design and development of advanced nanomaterials and biomaterials for biomedical, environmental, and technological applications. Her work includes drug delivery carriers, theranostics, MRI contrast agents, hierarchical hybrid structures, tissue engineering scaffolds, and wastewater treatment. She has established strong international collaborations with leading research institutions, including the Institute of Materials (USC, Spain) and the Institute of Biomaterials (FAU, Germany), participating in several European research initiatives. She has authored more than 25 peer-reviewed publications in high-impact Q1 journals and serves as Guest Editor for MDPI. She is also a key partner in the SIBILA Project (APVV-23-0097), contributing to the development of innovative biomaterial solutions. Her work combines fundamental materials science with translational research, aiming to create smart multifunctional systems that address current challenges in healthcare and sustainability.