Determining the gene expression and serum profile of the indicators linked to clinical endometritis susceptibility in Egyptian buffalo cows was the aim of this investigation. The buffalo cows that were enrolled were divided into two groups: forty infected buffalo cows with clinical endometritis and forty seemingly healthy buffalo cows that served as the control group. For the purposes of gene expression and biochemical analysis, ten milliliters of blood was obtained via jugular venipuncture from each buffalo cow. TLR4, IL-8, IL-17, NFKB, SLCA11A1, NCF4, Keap1, HMOX1, OXSR1, ST1P1, and SERP1 were manifestly expressed at much higher levels in the buffaloes with endometritis. On the other hand, the genes that encode SOD, CAT, NDUFS6, Nrf2, and PRDX2 were down-regulated. There was a significant (p < 0.05) elevation of the serum levels of non-esterified fatty acids (NEFAs), beta hydroxy butyric acid (BHBA), triglycerides (TGs), globulin, creatinine, and cortisol, along with a reduction in the serum levels of glucose, cholesterol, total protein albumin, urea, estrogen (E2), progesterone (P4), follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroxine (T4), prostaglandin F2 α (PGF2α), calcium, iron, and selenium, in the endometritis group in comparison with the control. However, no significant change was observed in the values of phosphorus, magnesium, copper, or zinc in either group. Within the selective breeding of naturally resistant animals, the variation in the genes under study and the changes in the serum profiles of the indicators under investigation may serve as a reference guide for reducing endometritis in Egyptian buffalo cows.

Background: The use of pre-workout supplements has surged among fitness practitioners, with various ingredients purported to enhance performance and recovery. This study aims to explore the potential link between pre-workout supplement consumption and aggression, as well as the correlation between the Big Five personality traits and aggression levels. Methods: The sample comprised 62 male fitness practitioners aged 20–55 years, divided into two groups: 32 pre-workout consumers and 30 non-consumers. Participants were assessed using the Buss and Perry Aggression Questionnaire and the NEO Five-Factor Inventory (NEO-FFI). Results: The results indicated no statistically significant differences in aggression levels between the supplement users and the control group. However, notable personality differences were observed, with pre-workout users showing lower Neuroticism and higher Agreeableness and Conscientiousness compared to non-users. Correlation analyses revealed a significant positive relationship between Neuroticism and all forms of aggression, while Agreeableness and Conscientiousness were negatively correlated with aggression. Conclusions: These findings suggest that personality traits may play a more substantial role in moderating aggression among pre-workout users than the supplements themselves. Further research is needed to clarify the potential long-term effects of pre-workout supplementation on aggression and personality dynamics.

Background/Objectives: Dental graduates make clinical decisions shaped by ethical principles, legal obligations, patient expectations, and private-practice economics. This study synthesized empirical findings from Romanian healthcare education and practice and proposes an exploratory model for teaching ethical decision-making in entrepreneurial dentistry. Methods: Exploratory conceptual framework development informed by four previously published Romanian healthcare studies examining business-ethics attitudes using the Attitudes Toward Business Ethics Questionnaire (ATBEQ), moral reasoning using an adapted Defining Issues Test-2 (DIT-2; 242 valid cases), scenario-based ethical decision-making (n = 244), and ethical reasoning profiles derived from the joint administration of the ATBEQ and 35-item scenario questionnaire (n = 277). Results: “It depends” accounted for 47.8% of scenario responses. Students and practitioners differed regarding vaccination of healthcare workers, risk-based insurance contributions, and organ-market policy (chi-square, df = 2, uncorrected). Practitioners endorsed law-oriented arguments more strongly but weighted patient autonomy more heavily at end of life. Idealism/Legalism showed an isolated exploratory association with fewer conditional responses (B = −0.69, 95% CI −1.28 to −0.11, p = 0.021); however, the overall regression model was not statistically significant and had low explanatory power (R² = 0.04, adjusted R² = 0.02, p = 0.08). Four ethical reasoning profiles were identified. Conclusions: The G.D.C. framework is a theory-informed, hypothesis-generating educational framework derived from mixed Romanian healthcare samples. It has not been validated specifically in entrepreneurial dentistry and requires prospective, dental-specific validation.