This page has only limited features, please log in for full access.

Unclaimed
Maria Maddalena Storelli
Biosciences, Biotechnlogies and Biopharmaceutical Department, University of Bari “Aldo Moro”, 70010 Valenzano, Bari, Italy

Basic Info


Fingerprints

Heavy metals
Risk Assessment
Food safety

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 20 February 2021 in Toxics
Reads 0
Downloads 0

Total mercury (THg), methylmercury (MeHg), and selenium (Se) concentrations were measured in various commercially important fish species. The benefit–risk binomial associated with these chemicals was assessed in children through the probability of exceeding the provisional tolerable weekly intakes (PTWIs) of the contaminants and the Se recommended dietary allowance (RDA). The Se:Hg molar ratios, selenium health benefit values (HBVSe), and monthly consumption rate limits (CRmm) for each species were also calculated. THg and Se were analyzed by atomic absorption spectrophotometer (Shimadzu, Milan, Italy), while MeHg was determined by Trace Ultra gas chromatograph connected with a PolarisQ MS (Thermo Fisher Scientific, Waltham, MA, USA). None of the analyzed fish had Hg levels above the European Community regulatory limits, while most large predators had MeHg levels over the threshold concentration set by US EPA. The estimated weekly intakes of THg and MeHg exceeded in many cases the PTWIs and the Se estimated daily intakes were provided from 0.71% to 2.75% of the RDA. Se:Hg molar ratios above 1 and positive HBVSe index suggested that Se in fish could be enough to alleviate the potential toxic effect of Hg. However, high-risk groups as children should consume fish in moderation because a large consumption pattern, especially of swordfish and tunas, might be of concern for health.

ACS Style

Grazia Barone; Arianna Storelli; Daniela Meleleo; Angela Dambrosio; Rita Garofalo; Antonio Busco; Maria Storelli. Levels of Mercury, Methylmercury and Selenium in Fish: Insights into Children Food Safety. Toxics 2021, 9, 39 .

AMA Style

Grazia Barone, Arianna Storelli, Daniela Meleleo, Angela Dambrosio, Rita Garofalo, Antonio Busco, Maria Storelli. Levels of Mercury, Methylmercury and Selenium in Fish: Insights into Children Food Safety. Toxics. 2021; 9 (2):39.

Chicago/Turabian Style

Grazia Barone; Arianna Storelli; Daniela Meleleo; Angela Dambrosio; Rita Garofalo; Antonio Busco; Maria Storelli. 2021. "Levels of Mercury, Methylmercury and Selenium in Fish: Insights into Children Food Safety." Toxics 9, no. 2: 39.

Article
Published: 12 November 2020 in Biological Trace Element Research
Reads 0
Downloads 0

This study provides valuable information on the levels of various trace metals (Pb, Cd, Hg, Zn, Cu, Cr) in meat products (baked ham, raw ham, mortadella, cured sausage, würstel, salami) from South Italy and calculates potential health risk toxicity associated with their consumption for the total population and for children. In the samples studied metal concentrations are within the permissible legal limits (Cd: 0.01–0.03 μg g−1 w.w., Hg: 0.01–0.02 μg g−1 w.w., Zn: 5.71–7.32 μg g−1 w.w., Cu: 1.08–1.21 μg g−1 w.w., Cr: 0.15–0.23 μg g−1 w.w.), except for Pb (Pb: 0.22–0.38 μg g−1 w.w.). The estimated intake values are within the provisional tolerable daily intake limits for toxic metals and recommended daily intake values for essential metals in both tested groups. The noncarcinogenic risk values of the individual metals indicate that there is no health risk, but their combined effects might constitute a potential risk for children. Furthermore, the cumulative cancer risk of all samples studied exceeds the recommended threshold risk limit (> 10−4) in both total population and children, indicating a risk of potential health problems for consumers especially for children, who are more vulnerable to toxic metal exposure.

ACS Style

Grazia Barone; Arianna Storelli; Nicoletta C. Quaglia; Rita Garofalo; Daniela Meleleo; Antonio Busco; Maria Maddalena Storelli. Trace Metals in Pork Meat Products Marketed in Italy: Occurrence and Health Risk Characterization. Biological Trace Element Research 2020, 199, 2826 -2836.

AMA Style

Grazia Barone, Arianna Storelli, Nicoletta C. Quaglia, Rita Garofalo, Daniela Meleleo, Antonio Busco, Maria Maddalena Storelli. Trace Metals in Pork Meat Products Marketed in Italy: Occurrence and Health Risk Characterization. Biological Trace Element Research. 2020; 199 (8):2826-2836.

Chicago/Turabian Style

Grazia Barone; Arianna Storelli; Nicoletta C. Quaglia; Rita Garofalo; Daniela Meleleo; Antonio Busco; Maria Maddalena Storelli. 2020. "Trace Metals in Pork Meat Products Marketed in Italy: Occurrence and Health Risk Characterization." Biological Trace Element Research 199, no. 8: 2826-2836.

Journal article
Published: 08 August 2020 in Biophysical Chemistry
Reads 0
Downloads 0

Aβ42 is a small peptide formed from 42 aminoacids that presents a great propensity to aggregate until it forms fibrils. Aβ42 aggregation and fibrillation are very complex processes whose molecular mechanisms seem to depend on characteristics intrinsic to the peptide molecule, as well as extrinsic factors. Peptide concentration, mean pH and several substances, including metal ions, are principal extrinsic factors for the oligomerization process. Different metals affect the aggregation of the Aβ42 molecule, and their toxicity favours the misfolding and aggregation of the peptide. In this study, we evaluate the effect of different concentrations of Cd2+ and Hg2+ on the Aβ42 peptide in solution by different methods. The toxicity of Aβ42 was evaluated with the MTT assay, while the aggregation process was monitored by single-channel measurements, electrophoresis and western blot. Cd2+ and Hg2+ seem to favour the formation of high-molecular-weight aggregates, to decrease ion channel turnover inside the membrane and to significantly increase Aβ42 toxicity.

ACS Style

Daniela Meleleo; Cesare Sblano; Maria Maddalena Storelli; Rosanna Mallamaci. Evidence of cadmium and mercury involvement in the Aβ42 aggregation process. Biophysical Chemistry 2020, 266, 106453 .

AMA Style

Daniela Meleleo, Cesare Sblano, Maria Maddalena Storelli, Rosanna Mallamaci. Evidence of cadmium and mercury involvement in the Aβ42 aggregation process. Biophysical Chemistry. 2020; 266 ():106453.

Chicago/Turabian Style

Daniela Meleleo; Cesare Sblano; Maria Maddalena Storelli; Rosanna Mallamaci. 2020. "Evidence of cadmium and mercury involvement in the Aβ42 aggregation process." Biophysical Chemistry 266, no. : 106453.

Journal article
Published: 03 May 2018 in International Journal of Environmental Research and Public Health
Reads 0
Downloads 0

Polychlorinated biphenyls (PCBs) and polychlorinated dibenzo-furans (PCDD/Fs) were measured in Mediterranean bluefin tuna (Thunnus thynnus) to verify the compliance with the EU regulations for food commercialization. The estimated intakes were also evaluated. The analyses were performed by gas chromatography-ion trap tandem mass spectrometry (GC-MS-MS). The PCBs were dominant (1132.0 ng g−1 l.w.), followed by PCDFs (23.2 pg g−1 l.w.) and PCDDs (8.5 pg g−1 l.w.). The pollutant levels (dl-PCBs: 0.7 pg TEQ/g w.w.; PCDD/Fs: 1.9 pg TEQ/g w.w.) and their sum expressed as TEQ values (2.6 pg TEQ/g w.w.) remained below the limits for human consumption proposed by the European Union. On the contrary, the sum of the six indicator non-dioxin-like PCBs (84.2 ng g−1 w.w.) was slightly above the maximum level fixed by the in-force legislation. The estimated dietary intakes for PCDD/Fs plus dl-PCBs were below the toxicological reference values (TRVs) set by various international bodies, while non-cancer and cancer risk assessment revealed a safety concern. Additionally, the estimated intake of ndl-PCBs exceeded the maximum levels set by different European countries. These findings suggest caution in tuna consumption together with an active and frequent surveillance of the chemical quality of its flesh.

ACS Style

Grazia Barone; Arianna Storelli; Rita Garofalo; Rosanna Mallamaci; Nicoletta C. Quaglia; Maria Maddalena Storelli. PCBs and PCDD/Fs in Bluefin Tuna: Occurrence and Dietary Intake. International Journal of Environmental Research and Public Health 2018, 15, 911 .

AMA Style

Grazia Barone, Arianna Storelli, Rita Garofalo, Rosanna Mallamaci, Nicoletta C. Quaglia, Maria Maddalena Storelli. PCBs and PCDD/Fs in Bluefin Tuna: Occurrence and Dietary Intake. International Journal of Environmental Research and Public Health. 2018; 15 (5):911.

Chicago/Turabian Style

Grazia Barone; Arianna Storelli; Rita Garofalo; Rosanna Mallamaci; Nicoletta C. Quaglia; Maria Maddalena Storelli. 2018. "PCBs and PCDD/Fs in Bluefin Tuna: Occurrence and Dietary Intake." International Journal of Environmental Research and Public Health 15, no. 5: 911.

Journal article
Published: 03 April 2018 in Toxics
Reads 0
Downloads 0

Trace element (Hg, Pb, Cd, Zn, Cu, Ni, and Cr) occurrence was determined in the muscle tissue of swordfish collected in the Mediterranean Sea to assess whether the intakes complied with the recommended levels for essential metals and permissible levels for toxic elements. Metals were analyzed by an atomic absorption spectrophotometer (Shimadzu AA 7000). The methodology of Target Hazard Quotient (THQ) was also evaluated. The ranking order of toxic metal concentration was Hg > Cd > Pb, while for essential elements the distribution pattern followed the sequence Zn > Cu > Ni > Cr. The Estimated Weekly Intakes (EWI) as well as THQ for Cd and Pb indicated that swordfish consumption did not pose a risk to human health, whereas the major concern was for Hg. Fish size-related changes in Hg concentrations resulted in high EWI and THQ values relative to larger fish consumption, implying a potential risk to human health. For consumer protection, catches of swordfish approximately above 44 kg should be avoided as these fish have a higher risk of containing toxic levels of Hg.

ACS Style

Grazia Barone; Angela Dambrosio; Arianna Storelli; Rita Garofalo; Vito Pietro Busco; Maria Maddalena Storelli. Estimated Dietary Intake of Trace Metals from Swordfish Consumption: A Human Health Problem. Toxics 2018, 6, 22 .

AMA Style

Grazia Barone, Angela Dambrosio, Arianna Storelli, Rita Garofalo, Vito Pietro Busco, Maria Maddalena Storelli. Estimated Dietary Intake of Trace Metals from Swordfish Consumption: A Human Health Problem. Toxics. 2018; 6 (2):22.

Chicago/Turabian Style

Grazia Barone; Angela Dambrosio; Arianna Storelli; Rita Garofalo; Vito Pietro Busco; Maria Maddalena Storelli. 2018. "Estimated Dietary Intake of Trace Metals from Swordfish Consumption: A Human Health Problem." Toxics 6, no. 2: 22.

Journal article
Published: 01 March 2018 in Journal of Food Composition and Analysis
Reads 0
Downloads 0
ACS Style

Grazia Barone; Angela Dambrosio; Arianna Storelli; Antonio Busco; Federica Ioanna; Nicoletta Cristiana Quaglia; Roberto Giacominelli-Stuffler; Maria Maddalena Storelli. Traditional Italian cheeses: Trace element levels and estimation of dietary intake. Journal of Food Composition and Analysis 2018, 66, 205 -211.

AMA Style

Grazia Barone, Angela Dambrosio, Arianna Storelli, Antonio Busco, Federica Ioanna, Nicoletta Cristiana Quaglia, Roberto Giacominelli-Stuffler, Maria Maddalena Storelli. Traditional Italian cheeses: Trace element levels and estimation of dietary intake. Journal of Food Composition and Analysis. 2018; 66 ():205-211.

Chicago/Turabian Style

Grazia Barone; Angela Dambrosio; Arianna Storelli; Antonio Busco; Federica Ioanna; Nicoletta Cristiana Quaglia; Roberto Giacominelli-Stuffler; Maria Maddalena Storelli. 2018. "Traditional Italian cheeses: Trace element levels and estimation of dietary intake." Journal of Food Composition and Analysis 66, no. : 205-211.

Journal article
Published: 01 January 2016 in Food and Chemical Toxicology
Reads 0
Downloads 0

The objectives of this study were to investigate the trace element (Hg, Cd, Pb, Cu, Zn, Ni, Fe, Cr and Se) and polychlorinated biphenyl (PCBs) content of several commercially available brands of green and black tea marketed in Italy. The concentrations these chemicals were found to be variable and largely dependent upon the type and brand of analysed tea. The most abundant element among the essential elements was Fe, followed by Zn, Cu, Se, Ni and Cr, whereas Pb was the predominant among the tested nonessential elements followed by Hg and Cd. Assessment based on several available guidelines showed that element content were low, except for Hg and Ni. The PCBs concentrations were generally low, with a homologue profile dominated by low-chlorinated congeners, namely three- and tetra-PCBs accounting for more than 60% of the total residue. Apart from trace elements, this is the first study documenting in detail the concentrations and congener distribution of PCBs in tea samples of different origin.

ACS Style

Grazia Barone; Roberto Giacominelli-Stuffler; Maria M. Storelli. Evaluation of trace metal and polychlorinated biphenyl levels in tea brands of different origin commercialized in Italy. Food and Chemical Toxicology 2016, 87, 113 -119.

AMA Style

Grazia Barone, Roberto Giacominelli-Stuffler, Maria M. Storelli. Evaluation of trace metal and polychlorinated biphenyl levels in tea brands of different origin commercialized in Italy. Food and Chemical Toxicology. 2016; 87 ():113-119.

Chicago/Turabian Style

Grazia Barone; Roberto Giacominelli-Stuffler; Maria M. Storelli. 2016. "Evaluation of trace metal and polychlorinated biphenyl levels in tea brands of different origin commercialized in Italy." Food and Chemical Toxicology 87, no. : 113-119.

Original articles
Published: 13 June 2015 in Food Additives & Contaminants: Part A
Reads 0
Downloads 0

Mercury (Hg) and cadmium (Cd) were quantified in fish, cephalopods and crustaceans from Italian supermarkets. Sample compliance with European dietary standards as well as human health risks according to provisional tolerable weekly intake (PTWI) and the methodology of target hazard quotient (THQ) were evaluated. Both element levels were under European legal limits, except for some fish having Hg and Cd contents exceeding or equal to critical values. Estimated weekly intakes (Hg: fish = 0.07–1.44 µg kg−1 bw week–1; cephalopods = 0.05–0.15 µg kg−1 bw week–1; crustaceans = 0.04–0.08 µg kg−1 bw week–1; and Cd: fish = 0.04–0.32 µg kg−1 bw week–1; cephalopods = 0.07–0.27 µg kg−1 bw week–1; crustaceans = 0.05–0.11 µg kg−1 bw week–1) as well as THQ < 1 were within safe limits. Although there seems to be no important risks associated with seafood consumption, Hg exposure was in some cases close to safety margins and thus levels of this metal should be under frequent surveillance.

ACS Style

Grazia Barone; Arianna Storelli; Rita Garofalo; Vito Pietro Busco; Nicoletta Cristiana Quaglia; Giuseppe Centrone; Maria Maddalena Storelli. Assessment of mercury and cadmium via seafood consumption in Italy: estimated dietary intake (EWI) and target hazard quotient (THQ). Food Additives & Contaminants: Part A 2015, 32, 1277 -1286.

AMA Style

Grazia Barone, Arianna Storelli, Rita Garofalo, Vito Pietro Busco, Nicoletta Cristiana Quaglia, Giuseppe Centrone, Maria Maddalena Storelli. Assessment of mercury and cadmium via seafood consumption in Italy: estimated dietary intake (EWI) and target hazard quotient (THQ). Food Additives & Contaminants: Part A. 2015; 32 (8):1277-1286.

Chicago/Turabian Style

Grazia Barone; Arianna Storelli; Rita Garofalo; Vito Pietro Busco; Nicoletta Cristiana Quaglia; Giuseppe Centrone; Maria Maddalena Storelli. 2015. "Assessment of mercury and cadmium via seafood consumption in Italy: estimated dietary intake (EWI) and target hazard quotient (THQ)." Food Additives & Contaminants: Part A 32, no. 8: 1277-1286.

Journal article
Published: 14 April 2015 in Journal of biological regulators and homeostatic agents
Reads 0
Downloads 0
ACS Style

G Di Guardo; A Falconi; A Di Francesco; Sandro Mazzariol; Cinzia Centelleghe; Cristina Casalone; Alessandra Pautasso; C Cocumelli; C Eleni; A Petrella; C E Di Francesco; Annalaura Sabatucci; L Leonardi; Anna Serroni; Letizia Marsili; Maria Maddalena Storelli; R Giacominelli-Stuffler. Western blot expression of 5-lipoxygenase in the brain from striped dolphins (stenella coeruleoalba) and bottlenose dolphins (tursiops truncatus) with or without encephalitis/meningo-encephalitis of infectious nature. Journal of biological regulators and homeostatic agents 2015, 29, 1 .

AMA Style

G Di Guardo, A Falconi, A Di Francesco, Sandro Mazzariol, Cinzia Centelleghe, Cristina Casalone, Alessandra Pautasso, C Cocumelli, C Eleni, A Petrella, C E Di Francesco, Annalaura Sabatucci, L Leonardi, Anna Serroni, Letizia Marsili, Maria Maddalena Storelli, R Giacominelli-Stuffler. Western blot expression of 5-lipoxygenase in the brain from striped dolphins (stenella coeruleoalba) and bottlenose dolphins (tursiops truncatus) with or without encephalitis/meningo-encephalitis of infectious nature. Journal of biological regulators and homeostatic agents. 2015; 29 (1):1.

Chicago/Turabian Style

G Di Guardo; A Falconi; A Di Francesco; Sandro Mazzariol; Cinzia Centelleghe; Cristina Casalone; Alessandra Pautasso; C Cocumelli; C Eleni; A Petrella; C E Di Francesco; Annalaura Sabatucci; L Leonardi; Anna Serroni; Letizia Marsili; Maria Maddalena Storelli; R Giacominelli-Stuffler. 2015. "Western blot expression of 5-lipoxygenase in the brain from striped dolphins (stenella coeruleoalba) and bottlenose dolphins (tursiops truncatus) with or without encephalitis/meningo-encephalitis of infectious nature." Journal of biological regulators and homeostatic agents 29, no. 1: 1.

Journal article
Published: 01 December 2014 in Food and Chemical Toxicology
Reads 0
Downloads 0

PCB and PCDD/F concentrations and congener specific profiles were determined in seafood (fish, cephalopods,\ud crustaceans) purchased in supermarkets in Southern Italy. The results intended to assess and\ud compare the levels and congener profiles among the various organisms and evaluate whether the pollutant\ud concentrations exceed the maximum permitted levels according to European Union guidelines.\ud Contaminant accumulation followed the order PCBs > PCDFs > PCDDs in all samples. Species-specific\ud bioaccumulation of contaminants and differences in PCB and PCDD/F profiles among the three different\ud groups of seafood were noted. Pollutant concentrations, given as sum of WHO-TEQ, in all samples (fish:\ud 0.28 pg g−1 wet wt; cephalopods: 0.01 pg g−1 wet wt; crustaceans: 0.03 pg g−1 wet wt) did not exceed the\ud maximum limits for human consumption. Also the sum of six indicator PCBs (fish: 0.07–16.7 ng g−1 wet\ud weight; cephalopods: 0.05–0.21 ng g−1 wet weight; crustaceans: 0.07–0.57 ng g−1 wet weight) was below\ud the level prescribed by the legislation in all the species tested. The estimated dietary intakes (fish: 0.52\ud TEQs/kg bw/week; cephalopods: 0.01 TEQs/kg bw/week; crustaceans: 0.02 TEQs/kg bw/week) were below\ud the tolerable weekly intake (TWI) proposed by the European Commission. Therefore, the samples analyzed\ud can be considered safe considering the levels obtained and the in-force legislation

ACS Style

Grazia Barone; Roberto Giacominelli-Stuffler; Rita Garofalo; Domenico Castiglia; Maria M. Storelli. PCBs and PCDD/PCDFs in fishery products: Occurrence, congener profile and compliance with European Union legislation. Food and Chemical Toxicology 2014, 74, 200 -205.

AMA Style

Grazia Barone, Roberto Giacominelli-Stuffler, Rita Garofalo, Domenico Castiglia, Maria M. Storelli. PCBs and PCDD/PCDFs in fishery products: Occurrence, congener profile and compliance with European Union legislation. Food and Chemical Toxicology. 2014; 74 ():200-205.

Chicago/Turabian Style

Grazia Barone; Roberto Giacominelli-Stuffler; Rita Garofalo; Domenico Castiglia; Maria M. Storelli. 2014. "PCBs and PCDD/PCDFs in fishery products: Occurrence, congener profile and compliance with European Union legislation." Food and Chemical Toxicology 74, no. : 200-205.

Journal article
Published: 01 November 2014 in Journal of Food Composition and Analysis
Reads 0
Downloads 0

PCBs including “indicator” and “dioxin-like” congeners were measured in a marine gastropod, Hexaplex trunculus, from Mediterranean areas exposed to anthropogenic pressure, to evaluate their compliance with European Union (EU) legislation. Total PCB concentrations showed location-dependent variation, and were higher in samples from Ionian Sea-Taranto (1001 ng g−1 lipid weight) compared with those from Adriatic Sea-Bari (519 ng g−1 lipid weight) and Adriatic-Sea-Brindisi (253 ng g−1 lipid weight). All sample concentrations were compliant with EU regulation limits for the sum of six “indicator” PCBs (Ionian Sea-Taranto: 40.7 ng g−1 wet weight; Adriatic Sea-Bari: 24.0 ng g−1 wet weight; Adriatic Sea-Brindisi: 11.0 ng g−1 wet weight). Also “dioxin-like” PCBs content expressed as toxic equivalent (TEQ) values, in samples from Adriatic Sea (Adriatic Sea-Bari: 2.48 pg WHO-TEQ/g wet weight; Adriatic Sea-Brindisi: 2.14 pg WHO-TEQ/g wet weight), were below the limit, while the specimens from the Ionian Sea (Ionian Sea-Taranto: 3.53 pg WHO-TEQ/g wet weight) showed levels exceeding the maximum threshold

ACS Style

Maria Maddalena Storelli; Angela Dambrosio; Arianna Storelli; Grazia Barone; Federica Ioanna; Giovanni Normanno. Levels of polychlorinated biphenyls (PCBs) in marine gastropod Hexaplex trunculus: Compliance with European Union legislation. Journal of Food Composition and Analysis 2014, 36, 35 -39.

AMA Style

Maria Maddalena Storelli, Angela Dambrosio, Arianna Storelli, Grazia Barone, Federica Ioanna, Giovanni Normanno. Levels of polychlorinated biphenyls (PCBs) in marine gastropod Hexaplex trunculus: Compliance with European Union legislation. Journal of Food Composition and Analysis. 2014; 36 (1-2):35-39.

Chicago/Turabian Style

Maria Maddalena Storelli; Angela Dambrosio; Arianna Storelli; Grazia Barone; Federica Ioanna; Giovanni Normanno. 2014. "Levels of polychlorinated biphenyls (PCBs) in marine gastropod Hexaplex trunculus: Compliance with European Union legislation." Journal of Food Composition and Analysis 36, no. 1-2: 35-39.

Journal article
Published: 01 June 2014 in Veterinary Parasitology
Reads 0
Downloads 0

Leukotrienes are products of the arachidonic acid metabolism and act as potent inflammatory mediators modulating the immune response and various physiological processes. This study evaluated the expression and activity of 5-lipoxygenase (5-LOX), the enzyme that catalyzes the first two steps in the biosynthesis of leukotrienes, in horses infected by larval cyathostomins. Tissue samples from dorsal and ventral colon, and from the cecum were collected from 16 horses slaughtered for human consumption. Samples were analyzed to estimate the burdens of encysted cyathostomin larvae and adult luminal stages, and then processed for the evaluation of biochemical parameters. No significant differences were found in the protein expression and enzymatic activity of 5-LOX between animals harbouring only adult parasites and negative horses. The protein expression and enzyme activity of 5-LOX were significantly higher in horses harbouring encysted larvae in comparison with horses free of encysted larvae. Although preliminary, these results indicate that 5-LOX is an important mediator in the course of horse cyathostominosis and further studies are warranted to unveil the possible role this enzyme plays in the pathogenesis of horse cyathostominosis, and its potential as a diagnostic marker

ACS Style

Roberto Giacominelli-Stuffler; Antonio Frangipane DI Regalbono; Donato Traversa; Thomas Geurden; Federica Marcer; Andrea Di Francesco; Chiara Angelini; Angela Di Cesare; Maria Maddalena Storelli; Mauro Maccarrone. The expression and activity of 5-LOX in the large intestine of horses harbouring encysted cyathostomin larvae. Veterinary Parasitology 2014, 203, 96 -101.

AMA Style

Roberto Giacominelli-Stuffler, Antonio Frangipane DI Regalbono, Donato Traversa, Thomas Geurden, Federica Marcer, Andrea Di Francesco, Chiara Angelini, Angela Di Cesare, Maria Maddalena Storelli, Mauro Maccarrone. The expression and activity of 5-LOX in the large intestine of horses harbouring encysted cyathostomin larvae. Veterinary Parasitology. 2014; 203 (1-2):96-101.

Chicago/Turabian Style

Roberto Giacominelli-Stuffler; Antonio Frangipane DI Regalbono; Donato Traversa; Thomas Geurden; Federica Marcer; Andrea Di Francesco; Chiara Angelini; Angela Di Cesare; Maria Maddalena Storelli; Mauro Maccarrone. 2014. "The expression and activity of 5-LOX in the large intestine of horses harbouring encysted cyathostomin larvae." Veterinary Parasitology 203, no. 1-2: 96-101.

Journal article
Published: 01 February 2014 in Science of The Total Environment
Reads 0
Downloads 0

Livers of 12 loggerhead sea turtles, Caretta caretta from the Eastern Mediterranean Sea (Adriatic Sea) were analyzed for the presence of polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Pathological and microbiological studies were also carried out in order to provide a contribution to the knowledge of causes of Mediterranean turtle death. Boat-strike injuries, entanglement in derelict fishing nets and ingestion of hooks and monofilament lines are the causes of death most frequently observed. PCBs (average: 1399ngg-1 fat basis) were the dominant chemicals, followed by PCDFs (average: 61pgg-1 fat basic) and PCDDs (average: 16pgg-1 fat basis). Hexachlorobiphenyl 153 accounted for the greatest proportion of the total PCBs, followed in order by PCB 138 and PCB 180 (14.1%). Mid-chlorinated, penta-through hepta-PCBs were among the top contributors to the sum of total PCBs, while the homolog pattern of PCCD/Fs was dominated by the tetra- to hexa-substituted congeners. In general the contamination level observed here was comparable with that reported in literature for specimens from different marine areas. Average TEQPCDD/Fs+Dl-PCBs concentration was 27.02pgg-1 wet weight (305.1pgg-1 lipid weight), with dioxin like-PCBs (93.4%) contributing much more to the total than PCDFs (3.9%) and PCDDs (2.7%). The appreciable concentration of TEQ would at first suggest that there are signs of potential threats to the health of these marine reptiles. Apart from PCBs, this is the first study documenting concentrations of PCDD/Fs in marine turtles from the Mediterranean Sea. Further investigations are urgently needed to characterize their contamination level for a better future protection and conservation of this endangered animal

ACS Style

Maria M. Storelli; Nicola Zizzo. Occurrence of organochlorine contaminants (PCBs, PCDDs and PCDFs) and pathologic findings in loggerhead sea turtles, Caretta caretta, from the Adriatic Sea (Mediterranean Sea). Science of The Total Environment 2014, 472, 855 -861.

AMA Style

Maria M. Storelli, Nicola Zizzo. Occurrence of organochlorine contaminants (PCBs, PCDDs and PCDFs) and pathologic findings in loggerhead sea turtles, Caretta caretta, from the Adriatic Sea (Mediterranean Sea). Science of The Total Environment. 2014; 472 ():855-861.

Chicago/Turabian Style

Maria M. Storelli; Nicola Zizzo. 2014. "Occurrence of organochlorine contaminants (PCBs, PCDDs and PCDFs) and pathologic findings in loggerhead sea turtles, Caretta caretta, from the Adriatic Sea (Mediterranean Sea)." Science of The Total Environment 472, no. : 855-861.

Journal article
Published: 16 December 2013 in Drug and Chemical Toxicology
Reads 0
Downloads 0

Hydroxytyrosol (2-(3,4dihydroxyphenyl)ethanol, (DPE), a phenolic compound present in olive oil, is known to have antioxidant properties. The aim of this study was to investigate the effect of DPE on oxidative stress induced by cadmium injections (CdCl2 2.5 mg/kg body weight) in spleen and testes of adult male rats. Oxidative stress was evaluated by measuring lipid peroxidation by thiobarbituric acid reactive substances (TBARS) as well as superoxide dismutase (SOD) and catalase (CAT) activities in cytosol and mitochondria. We found that in spleen no TBARS formation was detected following CdCl2 injections; however, DPE induces decrease in TBARS level in treated and untreated rats. On the contrary, we observed that DPE showed no effect on cadmium-induced lipid peroxidation in testes. Cytosolic activities of SOD and CAT decreased significantly only in spleen, where DPE restores the values to the control levels. Noteworthy, mitochondrial activities of SOD and CAT were strongly reduced by cadmium treatment both in spleen and testes, and DPE was not be able to restore their activity. Overall, the results from this study indicated that the DPE has different antioxidant efficiency in spleen and testis of cadmium intoxicated rats.

ACS Style

Elisabetta Merra; Giovanna Calzaretti; Antonella Bobba; Maria Maddalena Storelli; Elisabetta Casalino. Antioxidant role of hydroxytyrosol on oxidative stress in cadmium-intoxicated rats: different effect in spleen and testes. Drug and Chemical Toxicology 2013, 37, 420 -426.

AMA Style

Elisabetta Merra, Giovanna Calzaretti, Antonella Bobba, Maria Maddalena Storelli, Elisabetta Casalino. Antioxidant role of hydroxytyrosol on oxidative stress in cadmium-intoxicated rats: different effect in spleen and testes. Drug and Chemical Toxicology. 2013; 37 (4):420-426.

Chicago/Turabian Style

Elisabetta Merra; Giovanna Calzaretti; Antonella Bobba; Maria Maddalena Storelli; Elisabetta Casalino. 2013. "Antioxidant role of hydroxytyrosol on oxidative stress in cadmium-intoxicated rats: different effect in spleen and testes." Drug and Chemical Toxicology 37, no. 4: 420-426.

Comparative study
Published: 07 August 2013 in Ecotoxicology and Environmental Safety
Reads 0
Downloads 0

Metal concentrations (Hg, Cd, Pb, As, Cr, Cu, Zn and Ni) were measured in the liver of two fish, Torpedo nobiliana (electric ray) and Torpedo marmorata (marbled electric ray), from the Mediterranean Sea in order to comparatively investigate their current pollution status. Maximum mean levels of Hg were detected in electric ray (mean: 2.16 μg g−1 ww), while marbled electric ray accumulated especially Cd (mean: 0.06 μg g−1 ww), Cu (mean: 3.83 μg g−1 ww) and As (mean: 32.64 μg g−1 ww). The metal concentrations are similar to those reported in literature, except for Cd, As and Ni. Hg concentrations increased with increasing fish body length in both species, whilst no significant concentration–size relationship was found for other metals. To the best of our knowledge this is the first report providing information on trace metal levels and relationship between concentration and size of these cartilaginous fishes. Future studies on the concentrations and effects of environmental contaminants in various torpedinid species are surely needed.

ACS Style

Grazia Barone; Roberto Giacominelli-Stuffler; Maria M. Storelli. Comparative study on trace metal accumulation in the liver of two fish species (Torpedinidae): Concentration–size relationship. Ecotoxicology and Environmental Safety 2013, 97, 73 -77.

AMA Style

Grazia Barone, Roberto Giacominelli-Stuffler, Maria M. Storelli. Comparative study on trace metal accumulation in the liver of two fish species (Torpedinidae): Concentration–size relationship. Ecotoxicology and Environmental Safety. 2013; 97 ():73-77.

Chicago/Turabian Style

Grazia Barone; Roberto Giacominelli-Stuffler; Maria M. Storelli. 2013. "Comparative study on trace metal accumulation in the liver of two fish species (Torpedinidae): Concentration–size relationship." Ecotoxicology and Environmental Safety 97, no. : 73-77.

Journal article
Published: 01 August 2013 in Journal of Food Composition and Analysis
Reads 0
Downloads 0

Concentrations of 11 polycyclic aromatic hydrocarbons (PAHs) and toxic metals (Hg, Cd and Pb) were measured in three fish species [(Raja miraletus (brown ray), Lepidorhombus whiffiagonis (megrim) and Lophius piscatorius (angler)] from Mediterranean Sea (Adriatic Sea). No significant difference in PAHs and metal concentrations was encountered among the fish species examined. Total PAH concentrations ranged from 209.9ngg-1 wet weight to 227.2ngg-1 wet weight. Low-molecular weight (two and three rings) PAHs were observed dominating over the high molecular weight (from four to six rings) PAHs. With regard to metals, Hg exhibited the highest concentrations (0.68-0.98μgg-1 weight wet), followed by Pb (0.08-0.12μgg-1 weight wet) and Cd (0.05-0.10μgg-1 weight wet). The health risks by consumption of these species were assessed and did not present threat to public health concerning PAH, Pb and Cd intakes. However, the estimated exposure from Hg illustrates the importance of limiting the dietary consumption of larger-sized fish

ACS Style

Maria Maddalena Storelli; Grazia Barone; Veronica Giuliana Perrone; Arianna Storelli. Risk characterization for polycyclic aromatic hydrocarbons and toxic metals associated with fish consumption. Journal of Food Composition and Analysis 2013, 31, 115 -119.

AMA Style

Maria Maddalena Storelli, Grazia Barone, Veronica Giuliana Perrone, Arianna Storelli. Risk characterization for polycyclic aromatic hydrocarbons and toxic metals associated with fish consumption. Journal of Food Composition and Analysis. 2013; 31 (1):115-119.

Chicago/Turabian Style

Maria Maddalena Storelli; Grazia Barone; Veronica Giuliana Perrone; Arianna Storelli. 2013. "Risk characterization for polycyclic aromatic hydrocarbons and toxic metals associated with fish consumption." Journal of Food Composition and Analysis 31, no. 1: 115-119.

Journal article
Published: 09 July 2013 in Environmental Science and Pollution Research
Reads 0
Downloads 0

This study provides, for the first time, data regarding levels of toxic metals (Hg, Cd, and Pb) and organochlorine compounds (PCBs and DDTs) in various aromatic herbs as rosemary (Rosmarinus officinalis), sage (Salvia officinalis), laurel (Laurus nobilis), oregano (Origanum vulgare), and spearmint (Mentha viridis) collected in some towns of the Southern Italy with different anthropogenic and population pressure. Metal and organochlorine compound concentrations were determined using atomic absorption spectrophotometer and gas-chromatography mass spectrometer (GC/MS), respectively. Pb emerged as the most abundant element, followed by Cd and Hg, while between organochlorine compounds, PCB concentrations were higher than those of DDTs. The pollutant concentrations were found to vary depending on the different herbs. The highest Pb levels were observed in rosemary (1.66 μg g(-1) dry weight) and sage (1.41 μg g(-1) dry weight), this latter showing also the highest Cd concentrations (0.75 μg g(-1) dry weight). For PCBs, the major concentrations were found in rosemary (2.75 ng g(-1) dry weight) and oregano (2.39 ng g(-1) dry weight). The principal component analysis applied in order to evaluate possible similarities and/or differences in the contamination levels among sampling sites indicated differences area-specific contamination.

ACS Style

Maria Maddalena Storelli. Evaluation of toxic metal (Hg, Cd, Pb), polychlorinated biphenyl (PCBs), and pesticide (DDTs) levels in aromatic herbs collected in selected areas of Southern Italy. Environmental Science and Pollution Research 2013, 21, 946 -953.

AMA Style

Maria Maddalena Storelli. Evaluation of toxic metal (Hg, Cd, Pb), polychlorinated biphenyl (PCBs), and pesticide (DDTs) levels in aromatic herbs collected in selected areas of Southern Italy. Environmental Science and Pollution Research. 2013; 21 (2):946-953.

Chicago/Turabian Style

Maria Maddalena Storelli. 2013. "Evaluation of toxic metal (Hg, Cd, Pb), polychlorinated biphenyl (PCBs), and pesticide (DDTs) levels in aromatic herbs collected in selected areas of Southern Italy." Environmental Science and Pollution Research 21, no. 2: 946-953.

Journal article
Published: 11 January 2013 in Journal of Food Science
Reads 0
Downloads 0

Mercury (Hg), cadmium (Cd), and lead (Pb) were quantified in muscle tissue of 5 species of demersal fish (european conger eel, rosefish, brown ray, blackbellied angler, and red mullet) commonly consumed in Italy. In all species studied, Hg was the most abundant element, followed by Pb and Cd, which exhibited comparable levels. Cd and Pb concentrations did not differ either within individuals of the same species or among various species examined, whereas Hg accumulation was species-specific. Significant positive correlations between Hg concentrations and fish length for the 5 characterized species were observed. From a public health standpoint, Pb concentrations were under the legal limit for human consumption indicated by European Regulation, whereas Hg and Cd content occurred at levels exceeding the respective critical values in most of the samples examined. The estimated weekly intakes (EWIs) as well as the target hazard quotients (THQs) for Cd and Pb indicated that fish were safe for human consumption, whereas major concern was related to Hg. Fish size-related changes in Hg concentrations determined high THQ and EWI values relatively to larger size fish consumption of these species, except for red mullet, suggesting potential health human risk. A continuous surveillance system of Hg content in fishery products, especially in certain species that for physiological reasons concentrate Hg more easily than others is crucial for consumer health protection

ACS Style

Maria Maddalena Storelli; Grazia Barone. Toxic Metals (Hg, Pb, and Cd) in Commercially Important Demersal Fish from Mediterranean Sea: Contamination Levels and Dietary Exposure Assessment. Journal of Food Science 2013, 78, T362 -T366.

AMA Style

Maria Maddalena Storelli, Grazia Barone. Toxic Metals (Hg, Pb, and Cd) in Commercially Important Demersal Fish from Mediterranean Sea: Contamination Levels and Dietary Exposure Assessment. Journal of Food Science. 2013; 78 (2):T362-T366.

Chicago/Turabian Style

Maria Maddalena Storelli; Grazia Barone. 2013. "Toxic Metals (Hg, Pb, and Cd) in Commercially Important Demersal Fish from Mediterranean Sea: Contamination Levels and Dietary Exposure Assessment." Journal of Food Science 78, no. 2: T362-T366.

Journal article
Published: 31 October 2012 in Research in Veterinary Science
Reads 0
Downloads 0

Enzootic pneumonia by Mycoplasma hyopneumoniae and pleuropneumonia by Actinobacillus pleuropneumoniae are among the most common and economically relevant pulmonary diseases in swine herds. We herein investigated the activity and expression of 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) in healthy and diseased porcine lungs, by means of immunohistochemical, immunochemical and biochemical assays. Diseased lungs showed a significantly higher activity and expression of 5-LOX and COX-2 in a wide range of cell types, thus suggesting the likely involvement of both enzymes in the pathogenesis of bacterial porcine pneumonia. Consistently, increased enzyme activities were paralleled by increased leukotriene B4 (LTB4), a 5-LOX product and prostaglandin E2 (PGE2), a COX-2 product, content in diseased versus healthy lungs.

ACS Style

R. Giacominelli-Stuffler; G. Marruchella; Maria Maddalena Storelli; Annalaura Sabatucci; C.B. Angelucci; M. Maccarrone. 5-Lipoxygenase and cyclooxygenase-2 in the lungs of pigs naturally affected by enzootic pneumonia and porcine pleuropneumonia. Research in Veterinary Science 2012, 93, 898 -903.

AMA Style

R. Giacominelli-Stuffler, G. Marruchella, Maria Maddalena Storelli, Annalaura Sabatucci, C.B. Angelucci, M. Maccarrone. 5-Lipoxygenase and cyclooxygenase-2 in the lungs of pigs naturally affected by enzootic pneumonia and porcine pleuropneumonia. Research in Veterinary Science. 2012; 93 (2):898-903.

Chicago/Turabian Style

R. Giacominelli-Stuffler; G. Marruchella; Maria Maddalena Storelli; Annalaura Sabatucci; C.B. Angelucci; M. Maccarrone. 2012. "5-Lipoxygenase and cyclooxygenase-2 in the lungs of pigs naturally affected by enzootic pneumonia and porcine pleuropneumonia." Research in Veterinary Science 93, no. 2: 898-903.

Journal article
Published: 27 March 2012 in Bulletin of Environmental Contamination and Toxicology
Reads 0
Downloads 0

The present study provides novel data regarding levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides (DDTs) in muscle tissue of European conger eel (Conger conger) from Ionian Sea (Mediterranean Sea). The mean concentration of PCBs (891 ng g−1 lipid weight) was higher than those of DDTs (543 ng g−1 lipid weight). PCB pattern was dominated by higher chlorinated congeners (hexa-CBs: 69.3 %, penta-CBs: 17.2 %, hepta-CBs: 13.3 %). Regarding DDT pattern, p,p′-DDE was prevalent in all samples (85.5 %), suggesting no recent DDT input. The total 2,3,7,8-TCDD toxic equivalent (TEQs) of coplanar PCBs, including mono-and non-ortho congeners was 0.41 pg g−1 wet weight (29.92 pg g−1 lipid weight). The PCB and DDT levels, as well as TEQ concentrations were lower than most of the corresponding published data for fish from Mediterranean and non-Mediterranean regions, probably reflecting a moderately contaminated area.

ACS Style

Maria Maddalena Storelli; Veronica Giuliana Perrone; Vito Pietro Busco; Daniela Spedicato; Grazia Barone. Persistent Organic Pollutants (PCBs and DDTs) in European Conger Eel, Conger conger L., from the Ionian Sea (Mediterranean Sea). Bulletin of Environmental Contamination and Toxicology 2012, 88, 928 -932.

AMA Style

Maria Maddalena Storelli, Veronica Giuliana Perrone, Vito Pietro Busco, Daniela Spedicato, Grazia Barone. Persistent Organic Pollutants (PCBs and DDTs) in European Conger Eel, Conger conger L., from the Ionian Sea (Mediterranean Sea). Bulletin of Environmental Contamination and Toxicology. 2012; 88 (6):928-932.

Chicago/Turabian Style

Maria Maddalena Storelli; Veronica Giuliana Perrone; Vito Pietro Busco; Daniela Spedicato; Grazia Barone. 2012. "Persistent Organic Pollutants (PCBs and DDTs) in European Conger Eel, Conger conger L., from the Ionian Sea (Mediterranean Sea)." Bulletin of Environmental Contamination and Toxicology 88, no. 6: 928-932.