Due to specific immune recognition receptors on the surface of T cells, their membranes are promising mimic nanocarriers for delivering drugs to tumor lesions. However, this single targeting strategy potentially compromises therapy efficacy for tumor targeting due to inter‐ and intra‐heterogeneity of tumors. Azide (N ₃ ) or bicyclo [6.1.0] nonyne (BCN) modified unnatural sugars can be successfully incorporated into surface glycans of various tumor cells as artificial receptors, which is expected to overcome the insufficiency of single targeting. Based on this artificial tumor targeting strategy, indocyanine green nanoparticles (INPs) coated with N ₃ ‐labeled T cell membrane (N ₃ ‐TINPs) are constructed, which can specifically target the natural antigen and BCN artificial receptors on tumors through immune recognition and bioorthogonal chemistry, respectively. The results show that the fluorescence intensity in the tumors of mice treated with N ₃ ‐TINPs is 1.5 fold compared with that of the mice treated with unlabeled TINPs. The accumulated N ₃ ‐TINPs in the tumor significantly increase the photothermal therapeutic effect without adverse effect. Therefore, this T cell membrane mimicking nanoparticles based bioorthogonal chemistry may provide an alternative artificial targeting strategy for further tumor targeting photothermal therapy.

The title compound is a potential candidate for developing novel luminescence sensors for the selective sensing of nitrobenzene which can be deployed for explosives, Fe³⁺ and organic dyes.

A new three-dimensional microporous metal–organic framework based on Zn(II) clusters with the formula {[Zn₇(NDC)_5.5(μ₄-OH)₃]·7DMF}_n (1) (H₂NDC = 1,4-naphthalenedicarboxylic acid) had been synthesized and characterized. The MOF 1 displays an uncommon bsn topology, which is based on a unique heptanuclear Zn₇(OH)₃(CO₂)₁₁ cluster as a secondary building unit. The MOF had been employed as a photocatalyst for the photodegradation of model organic dyes rhodamine B and methyl violet in light. The results of photocatalytic experiments showed that 1 can successfully be employed as the photocatalyst for the benign decomposition of these dyes. A mechanism for the photcatalysis exhibited by 1 had been proposed using the results of density of states (DOS) and partial DOS calculations. The fluorescence properties of the MOF have been investigated, which revealed that 1 could be exploited as the luminescent sensor to recognize Fe³⁺ ions with perceptible quenching (K_sv = 6.55 × 10⁴ M–¹) and a limit of detection of 1.16 ppm.

A new metal–organic framework, formulated as {[Zn₂(L)(DMF)₃]·2DMF·2H₂O} (1), has been synthesized using a symmetrical rigid carboxylate ligand terphenyl-3,3′′,5,5′′-tetracarboxylic acid (H₄L). Single-crystal X-ray diffraction analysis shows that 1 possesses a 3D uninodal 4-c lonsdaleite (lon) topology based on binuclear Zn clusters. 1 behaves as a fluorescent chemosensor for highly selective and sensitive detection of Fe³⁺/Fe²⁺ ions, 2,4-dinitrophenol (2,4-DNP), p-nitrophenol (PNP) and 2,4,6-trinitrophenol (TNP). Furthermore, the photocatalytic properties of 1 for degradation of methyl violet (MV) and Rhodamine B (RhB) have been explored. The possible emission quenching of 1 in the presence of aromatic compounds has been addressed by theoretical calculations and the photocatalytic activity of 1 against organic dyes has been addressed using density of states (DOS) calculations.

A new Cd(II) based metal–organic framework (MOF), having formula {(CH₃)₂NH₂)₆[Cd₅(L)₄]·H₂O·3DMF}_n (1), has been synthesized based on a rigid tetracarboxylate ligand of terphenyl-3,3′′,5,5′′-tetracarboxylic acid (H₄L). 1 shows a complicated 3D tetranodal 3,3,4,8-c network with uncoordinated –COO⁻ groups. The highly selective luminescent sensing of 2,4-dinitrophenol (2,4-DNP), 2,4,6-trinitrophenol (TNP) and ferric ions was studied for 1 through the alleviation in its fluorescence intensity. The detection limit of 2,4-DNP was found to be 0.84 ppm, which is 20 times higher than that of 1,3,5-trimethylbenzene, demonstrating greater and selective quenching ability. The possible mechanism associated with the decrease in fluorescence intensity of 1 in the presence of nitroaromatics (NACs) has been addressed by theoretical calculations. Furthermore, 1 displays excellent capacity to adsorb methylene blue (MB) with high selectivity, and it maintains an almost identical adsorption performance after being recycled five times.